Commanders vs. 49ers Week 6 Betting Odds, Prediction and Picks: Purdy Leads Unbeaten Niners Into MNF

Washington

1-3

October 19, 2026, 8:15 PM ET

Levi's Stadium

San Francisco

5-0

Pointspread	+7.5 0
Moneyline	0
Over / Under	o +52

Matchup Odds

Pointspread	-7.5 0
Moneyline	0
Over / Under	u +52

Matchup Odds

Mon Oct 19 8:15PM ET

WAS +7.5

SF -7.5

Thu Oct 22 8:15PM ET

NE +3

50.5

CHI -3

Sun Oct 25 9:30AM ET

PIT -3

44.5

NO +3

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Offensive Leaders		Full Passing Yards Stats

1	Matthew Stafford Matthew Stafford	L.A. Rams Rams LAR	1794
2	C.J. Stroud C.J. Stroud	Houston Texans HOU	1714
3	Jordan Love Jordan Love	Green Bay Packers GB	1684
4	Dak Prescott Dak Prescott	Dallas Cowboys DAL	1639
5	Kirk Cousins Kirk Cousins	Las Vegas Raiders LV	1582

Offensive Leaders		Full Rushing Yards Stats

1	Kenneth Walker III Kenneth Walker III	Kansas City Chiefs KC	665
2	Bijan Robinson Bijan Robinson	Atlanta Falcons ATL	641
3	James Cook III James Cook III	Buffalo Bills BUF	627
4	Derrick Henry Derrick Henry	Baltimore Ravens BAL	534
5	Jahmyr Gibbs Jahmyr Gibbs	Detroit Lions DET	504

Offensive Leaders		Full Receiving Yards Stats

1	Jaxon Smith-Njigba Jaxon Smith-Njigba	Seattle Seahawks SEA	717
2	Chris Olave Chris Olave	New Orleans Saints NO	580
3	CeeDee Lamb CeeDee Lamb	Dallas Cowboys DAL	577
4	Drake London Drake London	Atlanta Falcons ATL	550
5	Christian Watson Christian Watson	Green Bay Packers GB	538

Defensive Leaders		Full Tackles Stats

1	Alex Singleton Alex Singleton	Denver Broncos DEN	66
2	Ernest Jones IV Ernest Jones IV	Seattle Seahawks SEA	59
3	Jacob Rodriguez Jacob Rodriguez	Miami Dolphins MIA	57
4	Nakobe Dean Nakobe Dean	Las Vegas Raiders LV	57
5	Anthony Hill Jr. Anthony Hill Jr.	Tennessee Titans TEN	56

Defensive Leaders		Full Sacks Stats

1	Will Anderson Jr. Will Anderson Jr.	Houston Texans HOU	7.5
2	Greg Rousseau Greg Rousseau	Buffalo Bills BUF	6
3	Chase Young Chase Young	New Orleans Saints NO	5.5
4	Dallas Turner Dallas Turner	Minnesota Vikings MIN	5.5
5	Elijah Ponder Elijah Ponder	New England Patriots NE	5.5

Defensive Leaders		Full Interceptions Stats

1	Renardo Green Renardo Green	San Francisco 49ers SF	3
2	Byron Murphy Jr. Byron Murphy Jr.	Minnesota Vikings MIN	3
3	Jevon Holland Jevon Holland	N.Y. Giants Giants NYG	3
4	Hezekiah Masses Hezekiah Masses	Las Vegas Raiders LV	3
5	Xavier McKinney Xavier McKinney	Green Bay Packers GB	3

American Football Conference - AFCW

team	w	l	pf	pa	home	away	div	conf	ats	o/u
Kansas City Chiefs KC	5	0	140	83	0-1	0-1	0-0	0-0	3-2	2-3
Denver Broncos DEN	4	2	114	125	1-1	1-2	0-0	0-0	4-2	1-5
Las Vegas Raiders LV	3	3	162	162	1-2	2-1	0-0	0-0	5-1	4-2
L.A. Chargers Chargers LAC	0	6	90	151	0-2	1-0	0-0	0-0	0-5	1-4

American Football Conference - AFCS

team	w	l	pf	pa	home	away	div	conf	ats	o/u
Jacksonville Jaguars JAC	4	2	154	104	3-1	1-1	0-0	0-0	3-2	1-4
Indianapolis Colts IND	2	4	144	164	1-2	1-2	0-0	0-0	3-3	4-2
Houston Texans HOU	2	4	144	143	0-2	2-1	0-0	0-0	2-4	3-3
Tennessee Titans TEN	1	5	84	129	1-1	1-2	0-0	0-0	4-2	2-4

American Football Conference - AFCE

team	w	l	pf	pa	home	away	div	conf	ats	o/u
Buffalo Bills BUF	5	1	197	171	2-1	1-0	0-0	0-0	4-1	4-1
New England Patriots NE	4	2	136	113	1-0	1-2	0-0	0-0	4-1	3-3
N.Y. Jets Jets NYJ	2	4	112	122	1-1	1-3	0-0	0-0	2-2	2-4
Miami Dolphins MIA	0	5	70	132	0-2	0-1	0-0	0-0	1-3	2-3

American Football Conference - AFCN

team	w	l	pf	pa	home	away	div	conf	ats	o/u
Cleveland Browns CLE	4	2	106	122	1-1	1-2	0-0	0-0	4-2	3-3
Pittsburgh Steelers PIT	4	2	137	128	1-1	1-2	0-0	0-0	4-2	4-2
Baltimore Ravens BAL	4	2	156	132	1-1	3-1	0-0	0-0	2-3	3-3
Cincinnati Bengals CIN	3	2	128	109	1-1	2-1	0-0	0-0	2-2	3-2

American Football Conference - AFCW

Denver Broncos DEN	0-0	0-0	0-0	0-0
L.A. Chargers Chargers LAC	0-0	0-0	0-0	0-0
Las Vegas Raiders LV	0-0	0-0	0-0	0-0

American Football Conference - AFCS

Jacksonville Jaguars JAC	0	0	0	0	0	0-0	0-0	0-0	0-0
Tennessee Titans TEN	0	0	0	0	0	0-0	0-0	0-0	0-0

American Football Conference - AFCE

Buffalo Bills BUF	0-0	0-0	0-0	0-0
New England Patriots NE	0-0	0-0	0-0	0-0
N.Y. Jets Jets NYJ	0-0	0-0	0-0	0-0

American Football Conference - AFCN

Baltimore Ravens BAL	0-0	0-0	0-0	0-0
Cincinnati Bengals CIN	0-0	0-0	0-0	0-0
Cleveland Browns CLE	0-0	0-0	0-0	0-0
Pittsburgh Steelers PIT	0-0	0-0	0-0	0-0

American Football Conference

National Football Conference - NFCW

team	w	l	pf	pa	home	away	div	conf	ats	o/u
San Francisco 49ers SF	5	0	154	93	0-1	2-0	0-0	0-0	4-1	3-2
Seattle Seahawks SEA	3	3	148	122	2-1	1-2	0-0	0-0	2-4	3-3
Arizona Cardinals ARI	2	4	126	178	0-2	2-2	0-0	0-0	3-3	3-3
L.A. Rams Rams LAR	2	4	135	138	1-3	1-1	0-0	0-0	2-4	2-4

National Football Conference - NFCS

team	w	l	pf	pa	home	away	div	conf	ats	o/u
Carolina Panthers CAR	3	2	146	123	1-1	2-1	0-0	0-0	3-2	2-3
Atlanta Falcons ATL	2	4	142	153	0-1	2-1	0-0	0-0	2-4	4-2
New Orleans Saints NO	2	4	152	178	0-1	2-1	0-0	0-0	3-3	4-2
Tampa Bay Buccaneers TB	1	5	119	138	1-0	1-1	0-0	0-0	0-4	3-2

National Football Conference - NFCE

team	w	l	t	pf	pa	home	away	div	conf	ats	o/u
N.Y. Giants Giants NYG	3	2	1	136	140	3-1	0-1	0-0	0-0	3-3	3-3
Philadelphia Eagles PHI	2	4	0	106	137	1-2	1-2	0-0	0-0	1-5	1-5
Dallas Cowboys DAL	2	4	0	151	159	1-2	1-2	0-0	0-0	2-2	3-2
Washington Commanders WAS	1	3	1	115	149	1-1	0-2	0-0	0-0	2-3	3-2

National Football Conference - NFCN

team	w	l	pf	pa	home	away	div	conf	ats	o/u
Minnesota Vikings MIN	5	0	109	64	0-1	1-1	0-0	0-0	4-1	1-4
Green Bay Packers GB	4	2	127	125	2-1	2-1	0-0	0-0	2-2	2-4
Chicago Bears CHI	4	2	150	119	2-1	2-1	0-0	0-0	4-2	2-4
Detroit Lions DET	3	2	164	148	1-0	1-2	0-0	0-0	2-3	5-0

National Football Conference - NFCW

L.A. Rams Rams LAR	0-0	0-0	0-0	0-0
San Francisco 49ers SF	0-0	0-0	0-0	0-0
Arizona Cardinals ARI	0-0	0-0	0-0	0-0

National Football Conference - NFCS

Carolina Panthers CAR	0-0	0-0	0-0	0-0
Tampa Bay Buccaneers TB	0-0	0-0	0-0	0-0
Atlanta Falcons ATL	0-0	0-0	0-0	0-0
New Orleans Saints NO	0-0	0-0	0-0	0-0

National Football Conference - NFCE

N.Y. Giants Giants NYG	0-0	0-0	0-0	0-0
Dallas Cowboys DAL	0-0	0-0	0-0	0-0
Washington Commanders WAS	0-0	0-0	0-0	0-0

National Football Conference - NFCN

Green Bay Packers GB	0-0	0-0	0-0	0-0
Chicago Bears CHI	0-0	0-0	0-0	0-0
Detroit Lions DET	0-0	0-0	0-0	0-0
Minnesota Vikings MIN	0-0	0-0	0-0	0-0

National Football Conference

Nfl Betting News and Matchup Odds

Commanders vs. 49ers Week 6 Betting Odds, Prediction and Picks: Purdy Leads Unbeaten Niners Into MNF

WAS +7.5

SF -7.5

NE +3

CHI -3

PIT -3

NO +3

NFL Betting News

League Leaders