NFL NFL Jets vs. Saints Point Spread: NFL Week 16 Odds, Prediction Brian Burden Last Updated: December 18, 2025 It took most of the season, as well as a change at the quarterback position, but the New Orleans Saints are finally gaining some momentum. JETS Away 17 SAINTS Home 28 ScorePredictions Matchup
NFL NFL Chargers vs. Cowboys Point Spread: NFL Week 16 Odds, Prediction Brian Burden Last Updated: December 18, 2025 The Chargers went on the road and eliminated division rival Kansas City from the playoffs last week and will look to do the same thing when they travel to Dallas to face the Cowboys on Sunday. CHARGERS Away 24 COWBOYS Home 21 ScorePredictions Matchup
NFL NFL Falcons vs. Cardinals Point Spread: NFL Week 16 Odds, Prediction Nik Kowalski Last Updated: December 18, 2025 The Arizona Cardinals host the Atlanta Falcons on Sunday afternoon in what could be a candidate for most combined passing attempts in an NFL game. FALCONS Away 30 CARDINALS Home 22 ScorePredictions Matchup
NFL NFL Jaguars vs. Broncos Point Spread: NFL Week 16 Odds, Prediction Nik Kowalski Last Updated: December 18, 2025 Two of the top contenders in the AFC go head-to-head on Sunday afternoon when the Jacksonville Jaguars face off with the conference-leading Denver Broncos. JAGUARS Away 24 BRONCOS Home 27 ScorePredictions Matchup
NFL NFL Eagles vs. Commanders Point Spread: NFL Week 16 Odds, Prediction Brian Burden Last Updated: December 17, 2025 Now that the defending Super Bowl champion Philadelphia Eagles have snapped out of a three-game losing streak, they can move forward with ending another long skid. EAGLES Away 27 COMMANDERS Home 13 ScorePredictions Matchup
NFL NFL Buccaneers vs. Panthers Point Spread: NFL Week 16 Odds, Prediction Caleb Wilfinger Last Updated: December 17, 2025 Week 16 of the 2025 NFL season will continue with a massive matchup in the NFC South, as the Bucs head to Carolina to take on the Panthers at 1:00 pm ET on Sunday. BUCCANEERS Away 23 PANTHERS Home 24 ScorePredictions Matchup
NFL NFL Bills vs. Browns Point Spread: NFL Week 16 Odds, Prediction Caleb Wilfinger Last Updated: December 17, 2025 Following another wild weekend of football, Week 16 has several compelling matchups, including a sneaky under-the-radar game in Cleveland between the Bills and Browns at Huntington Bank Field. BILLS Away 24 BROWNS Home 13 ScorePredictions Matchup
NFL NFL Patriots vs. Ravens Point Spread: NFL Week 16 Odds, Prediction Brian Burden Last Updated: December 17, 2025 The New England Patriots showed they are vulnerable last weekend, while the Baltimore Ravens showed they still have some fight left. PATRIOTS Away 21 RAVENS Home 24 ScorePredictions Matchup
NFL NFL Rams vs. Seahawks Point Spread: NFL Week 16 TNF Odds, Prediction Brian Burden Last Updated: December 16, 2025 Jaxon Smith-Njigba, the NFL leader in receiving yards (1,541), is +100 to record 100+ receiving yards on Thursday night. RAMS Away 24 SEAHAWKS Home 21 ScorePredictions Matchup
NFL NFL Packers vs. Bears Point Spread: NFL Week 16 Odds, Prediction Matthew Lowrimore Last Updated: December 16, 2025 The NFL regular season has nearly reached its conclusion, and Week 16 has a ton of crucial matchups, including an NFC North divisional game between the Green Bay Packers and the Chicago Bears. PACKERS Away 24 BEARS Home 27 ScorePredictions Matchup
NFL NFL Bengals vs. Dolphins Point Spread: NFL Week 16 Odds, Prediction Payton Matthews Last Updated: December 16, 2025 Two teams without much to play for meet in Week 16, with the Miami Dolphins hosting the Cincinnati Bengals. BENGALS Away 24 DOLPHINS Home 27 ScorePredictions Matchup
NFL NFL 49ers vs. Colts Point Spread: NFL Week 16 MNF Odds, Prediction Payton Matthews Last Updated: December 15, 2025 The Philip Rivers comeback story continues in Week 16 as the fading Indianapolis Colts play host to the San Francisco 49ers. 49ERS Away 23 COLTS Home 17 ScorePredictions Matchup
NFL NFL Titans vs. 49ers Point Spread: NFL Week 15 Odds, Prediction Daniel Coyle Last Updated: December 11, 2025 The San Francisco 49ers enjoy a golden opportunity to strengthen their grasp on a playoff spot and keep pace with the NFC West division leaders when they host the bottom-feeding Tennessee Titans on Sunday afternoon in NFL Week 15 betting action at Levi’s Stadium. TITANS Away 16 49ERS Home 29 ScorePredictions Matchup
NFL NFL Colts vs. Seahawks Point Spread: NFL Week 15 Odds, Prediction Daniel Coyle Last Updated: December 11, 2025 The Seattle Seahawks are heavy double-digit favourites as they prepare to host the fading Indianapolis Colts in Week 15. COLTS Away 10 SEAHAWKS Home 31 ScorePredictions Matchup
NFL NFL Commanders vs. Giants Point Spread: NFL Week 15 Odds, Prediction Brian Burden Last Updated: December 11, 2025 The NFL’s most depressing matchup this weekend takes place in East Rutherford, NJ, as the New York Giants host the Washington Commanders on Sunday at 1:00 pm ET. COMMANDERS Away 21 GIANTS Home 24 ScorePredictions Matchup
NFL NFL Raiders vs. Eagles Point Spread: NFL Week 15 Odds, Prediction Ricky Dimon Last Updated: December 11, 2025 The Philadelphia Eagles can only hope that a date with the lowly Las Vegas Raiders is just what the doctor ordered to cure their ailments. RAIDERS Away 14 EAGLES Home 23 ScorePredictions Matchup
NFL NFL Packers vs. Broncos Point Spread: NFL Week 15 Odds, Prediction Ricky Dimon Last Updated: December 11, 2025 Week 15 of the 2025 NFL season is highlighted in part by a potential Super Bowl preview between the Green Bay Packers and Denver Broncos on Sunday afternoon in Denver. PACKERS Away 21 BRONCOS Home 20 ScorePredictions Matchup
NFL NFL Bills vs. Patriots Point Spread: NFL Week 15 Odds, Prediction Brian Burden Last Updated: December 11, 2025 The New England Patriots, riding their longest winning streak in a decade, look to clinch the AFC East crown when they host the Buffalo Bills on Sunday at 1:00 pm ET. BILLS Away 28 PATRIOTS Home 31 ScorePredictions Matchup
NFL NFL Lions vs. Rams Point Spread: NFL Week 15 Odds, Prediction Nik Kowalski Last Updated: December 11, 2025 The Detroit Lions quest for a playoff spot doesn’t get any easier this weekend when they visit the NFC-leading Los Angeles Rams on Sunday. LIONS Away 33 RAMS Home 27 ScorePredictions Matchup
NFL NFL Panthers vs. Saints Point Spread: NFL Week 15 Odds, Prediction Nik Kowalski Last Updated: December 11, 2025 The New Orleans Saints can continue to play spoiler when they host the Carolina Panthers in a divisional bout on Sunday. PANTHERS Away 17 SAINTS Home 23 ScorePredictions Matchup
