CFL

2025 CFL Week 16 Picks and Betting Odds: Quarterback health is key around the league

• Jordan Ramsay

• Last Updated: September 19, 2025

Week 16 of the CFL season is here and we've got a full slate of games with playoff implications on the line.

CFL

CFL

Alouettes vs. Argonauts Prediction: CFL Week 16 Point Spread, Odds

• Jordan Ramsay

• Last Updated: September 19, 2025

There's major playoff implications on the line in Week 16 as the Argonauts host the Alouettes in an East Division matchup.

CFL

CFL

Lions vs. Stampeders Prediction: CFL Week 16 Point Spread, Odds

• Daniel Coyle

• Last Updated: September 18, 2025

The Calgary Stampeders can pull to within two points of the idle Saskatchewan Roughriders in the race for the top of the CFL West standings with a win on Friday, when they host the BC Lions in CFL Week 16 betting action.

CFL

CFL

Elks vs. Tiger-Cats Prediction: CFL Week 16 Point Spread, Odds

• Payton Matthews

• Last Updated: September 18, 2025

The last game in Week 16 around the CFL is Saturday evening and could be the biggest mismatch of the weekend as East Division-leading Hamilton hosts West last-place Edmonton.

CFL

CFL

Blue Bombers vs. RedBlacks Prediction: CFL Week 16 Point Spread, Odds

• Payton Matthews

• Last Updated: September 17, 2025

The first game of a Saturday doubleheader in Week 16 around the CFL features Winnipeg trying to snap a three-game losing streak as it visits East Division last-place Ottawa in a matinee.

CFL

CFL

Alouettes vs. Roughriders Prediction: CFL Week 15 Point Spread, Odds

• Daniel Coyle

• Last Updated: September 13, 2025

The Montreal Alouettes look to put the brakes on a five-game losing streak that has threatened to dump them out of the playoff picture in the CFL East standings when they visit the league-leading Saskatchewan Roughriders on Saturday night in CFL Week 15 betting action at Mosaic Stadium.

CFL

CFL

Elks vs. Argonauts Prediction: CFL Week 15 Point Spread, Odds

• Daniel Coyle

• Last Updated: September 12, 2025

CFL Week 15 betting action on Saturday afternoon features a clash of teams in desperate need of points to return to playoff contention as the Toronto Argonauts host the Edmonton Elks at BMO Field.

CFL

CFL

Blue Bombers vs. Tiger-Cats Prediction: CFL Week 15 Point Spread, Odds

• Jordan Ramsay

• Last Updated: September 12, 2025

The Hamilton Tiger-Cats will look to improve their position at the top of the East Division standings on Friday night when they host the Winnipeg Blue Bombers.

CFL

2025 CFL Week 15 Picks and Betting Odds: Lions head home looking for revenge against RedBlacks

• Jordan Ramsay

• Last Updated: September 11, 2025

Betting odds and picks for all four Week 15 games in the CFL.

CFL

CFL Odds: Blue Bombers QB Zach Collaros out for Friday’s game against Tiger-Cats

• Jordan Ramsay

• Last Updated: September 11, 2025

Zach Collaros is dealing with a neck injury suffered in Winnipeg's 21-13 Week 14 loss against Saskatchewan.