Sports Interaction

Panthers vs. 49ers Prediction, Odds & Stats - November 24, 2025

Final Score
Carolina
Panthers
San Francisco
49ers
9
20
Carolina Panthers
San Francisco 49ers
Scoreboard 1 2 3 4 Odds
Carolina Panthers 8-9 0 3 6 0 +49
San Francisco 49ers 12-5 7 3 7 3 -7

Latest Encounters

Date Result Competition Stats Recap
01/17/26
San Francisco 49ers SF ( 12-5 )
Seattle Seahawks SEA ( 14-3 )
6   -   41
NFC West
01/11/26
San Francisco 49ers SF ( 12-5 )
Philadelphia Eagles PHI ( 11-6 )
23   -   19
NFC West
01/10/26
L.A. Rams Rams LAR ( 12-5 )
Carolina Panthers CAR ( 8-9 )
34   -   31
NFC West
01/03/26
Seattle Seahawks SEA ( 14-3 )
San Francisco 49ers SF ( 12-5 )
13   -   3
NFC West
01/03/26
Carolina Panthers CAR ( 8-9 )
Tampa Bay Buccaneers TB ( 8-9 )
14   -   16
NFC South
12/28/25
Chicago Bears CHI ( 11-6 )
San Francisco 49ers SF ( 12-5 )
38   -   42
NFC North
12/28/25
Seattle Seahawks SEA ( 14-3 )
Carolina Panthers CAR ( 8-9 )
27   -   10
NFC West
12/22/25
San Francisco 49ers SF ( 12-5 )
Indianapolis Colts IND ( 8-9 )
48   -   27
NFC West
12/21/25
Tampa Bay Buccaneers TB ( 8-9 )
Carolina Panthers CAR ( 8-9 )
20   -   23
NFC South
12/14/25
Carolina Panthers CAR ( 8-9 )
New Orleans Saints NO ( 6-11 )
17   -   20
NFC South
12/14/25
Tennessee Titans TEN ( 3-14 )
San Francisco 49ers SF ( 12-5 )
24   -   37
AFC South
11/30/25
L.A. Rams Rams LAR ( 12-5 )
Carolina Panthers CAR ( 8-9 )
28   -   31
NFC West

Line History

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Matchup Details

team win loss last 10 w/l streak ats money home away total
Carolina Panthers Carolina Panthers
6 5 4-6 2L 7-4 0 0-0 0-0 6-5
San Francisco 49ers San Francisco 49ers
7 4 7-3 1L 6-5 0 0-0 0-0 7-4

Recent Meetings

date home-away ats o/u SF:Total Net Yards SF:Net Rushing Yards SF:Passing Yards CAR:Total Net Yards CAR:Net Rushing Yards CAR:Passing Yards
11/24/2025 SF 20 - CAR 9 SF -7 Under 49 340 147 193 230 69 161
10/09/2022 CAR 15 - SF 37 SF -6 Over 39.5 397 153 244 308 64 244
10/27/2019 SF 51 - CAR 13 SF -4.5 Over 42 230 130 100 388 232 156
09/10/2017 SF 3 - CAR 23 CAR -4.5 Under 45.5 287 116 171 217 51 166
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
01/10/2026 CAR 31 - LAR 34 W +10 Over 46.5 411 116 295
01/03/2026 TB 16 - CAR 14 W +3 Under 42.5 285 19 266
12/28/2025 CAR 10 - SEA 27 L +7.5 Under 42.5 288 163 125
12/21/2025 CAR 23 - TB 20 W +2.5 Under 44.5 296 169 127
12/14/2025 NO 20 - CAR 17 L -2.5 Under 41.5 281 127 154
11/30/2025 CAR 31 - LAR 28 W +9.5 Over 45 379 152 227
11/24/2025 SF 20 - CAR 9 L +7 Under 49 230 69 161
11/16/2025 ATL 27 - CAR 30 W +3.5 Over 42 486 67 419
11/09/2025 CAR 7 - NO 17 L -4.5 Under 38.5 388 122 266
11/02/2025 GB 13 - CAR 16 W +11.5 Under 43.5 265 163 102
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
01/17/2026 SEA 41 - SF 6 L +7 Over 45.5 281 175 106
01/11/2026 PHI 19 - SF 23 W +5.5 Under 46.5 307 140 167
01/03/2026 SF 3 - SEA 13 L +2.5 Under 48.5 173 53 120
12/28/2025 SF 42 - CHI 38 W -3 Over 51.5 496 200 296
12/22/2025 IND 27 - SF 48 W -5.5 Over 46.5 312 58 254
12/14/2025 SF 37 - TEN 24 W -12.5 Over 44.5 430 138 292
11/30/2025 CLE 8 - SF 26 W -6.5 Under 41.5 253 138 115
11/24/2025 SF 20 - CAR 9 W -7 Under 49 340 147 193
11/16/2025 ARI 22 - SF 41 W -3.5 Over 47.5 488 36 452
11/09/2025 SF 26 - LAR 42 L +6 Over 46.5 393 74 319

Matchup Edge - Scoring Stats

avg rank edge in rank avg
18.29 26 Points Per Game 9 25.71
22.35 15 Points Allowed Per Game 13 21.82
3.71 23 1st Quarter Scoring Per Game 8 5.59
4.29 11 1st Quarter Scoring Allowed Per Game 9 4.06
4.24 23 2nd Quarter Scoring Per Game 8 7.71
8.94 24 2nd Quarter Scoring Allowed Per Game 14 7.12
4.18 16 3rd Quarter Scording Per Game 9 5.47
4.29 12 3rd Quarter Scoring Allowed Per Game 12 4.29
6 17 4th Quarter Scoring Per Game 12 6.76
4.82 4 4th Quarter Scoring Allowed Per Game 14 6.35
53.3 19 Red Zone Efficiency 4 65.2
295.59 26 Total Yards Per Game 7 351.41
9.76 19 Total Yards Per Play 15 10.41
4.29 17 Rushing Yards Per Play 27 3.78
30.29 18 Passing Attempts Per Game 9 33.76
9.26 25 Passing Yards Per Completion 14 10.44
1.41 10 Passing Tds Per Game 4 1.94
19.35 19 Completions Per Game 4 23.41
63.9 16 Completion % 3 69.3
87.88 22 Qb Rating 6 98.76
2.06 16 Defense Sacks Per Game 19 1.59
0.71 9 Defense Interceptions Per Game 5 0.94
0.94 6 Opponent Fumbles Per Game 10 1.18
0.65 3 Opponent Fumbles Lost Per Game 8 0.35
5.59 4 Penalties Per Game 2 4.88
44.82 7 Penalty Yards Per Game 3 38.29
23 11 Takeaway / Giveaway Differential 10 22
3.14 25 Yards Per Punt Return 3 6.61
24.15 29 Yards Per Kickoff Return 7 27.16

Odds Analysis

Team Rankings

offence
Carolina Panthers CAR
Season stats rank
Total Yards 295.6 27
Passing Yards 179.29 26
Rushing Yards 116.29 19
Points Scored 18.29 27
Field Goal % 0.83 22
San Francisco 49ers SF
Season stats rank
Total Yards 351.4 8
Passing Yards 244.53 5
Rushing Yards 106.88 24
Points Scored 25.71 10
Field Goal % 0.92 6
defence
Carolina Panthers CAR
Season stats rank
Total Yards 295.6 27
Passing Yards 179.29 26
Rushing Yards 116.29 19
Points Scored 18.29 27
Field Goal % 0.83 22
San Francisco 49ers SF
Season stats rank
Total Yards 351.4 8
Passing Yards 244.53 5
Rushing Yards 106.88 24
Points Scored 25.71 10
Field Goal % 0.92 6

Injuries

Carolina Panthers CAR
San Francisco 49ers SF

Line Up - Last Game

Pitchers
POS Player
Hitters
POS Player
Pitchers
POS Player
Hitters
POS Player