After suffering their first defeat of the season at the hands of PSG in midweek, Manchester City return to Premier League action at home to Ipswich Town.
The Chicago Bears visit Atlanta in a tight Week 6 matchup, with Caleb Williams nearing a return and both teams looking to bounce back from disappointing losses.
One of just three teams yet to taste defeat in the 2026/27 Premier League season, Everton welcome Chelsea to Merseyside for a blockbuster lunchtime kick-off on Saturday afternoon.
The Colts have dominated in head-to-head action versus the Titans, claiming six straight victories while averaging 31.8 points per game over that stretch.
The Ravens visit Cleveland with first place in the AFC North on the line, while Lamar Jackson’s uncertain status adds another layer to a matchup between two strong recent home and road ATS teams.