Bills vs. Raiders NFL Week 6 Betting Odds, Picks: Buffalo, Las Vegas combine for highest Over/Under of the week
The Buffalo Bills look for their fifth victory in six games when they visit the Las Vegas Raiders on Sunday afternoon.
Buffalo improved to 4-1 with a dramatic 37-34 overtime victory over the Los Angeles Rams on Monday. Josh Allen led the comeback, while James Cook helped power the rushing attack.
Las Vegas dropped to 3-2 following a 45-17 defeat to New England. The Raiders have lost two consecutive games after opening the season with three victories.
Bills vs. Raiders Kickoff, Weather, TV, Streaming Info
Kickoff is Sunday at 4:25 p.m. ET at Allegiant Stadium in Las Vegas. The game airs on CBS and streams on Paramount+ and NFL+ for eligible viewers.
Sunday’s forecast calls for mostly sunny skies and approximately 78°F at the 1:25 p.m. local kickoff, warming to 80°F by 3 p.m.. The precipitation chance is just 3.0 per cent.
Allegiant Stadium’s enclosed, climate-controlled environment eliminates weather concerns.
NFL Betting Odds, Point Spread, Trends
Buffalo is a 4.5-point favourite on the NFL odds with a -275 moneyline, while Las Vegas is listed at +225. The total is 53.5 points.
The Bills are 4-1 against the spread this season, while the Raiders are also 4-1 ATS.
The Over has hit in seven consecutive meetings between these teams.
These teams last played each other in September 2023, when Buffalo won 38-10.
NFL Player Odds and Props
Buffalo Bills
Josh Allen anytime touchdown (-170)
Allen has scored eight rushing touchdowns through five games, leading the NFL. His ability to run near the goal line makes him a strong candidate against a Raiders defence that has struggled to contain opposing rushing attacks.
James Cook Over 91.5 rushing yards (-113)
Cook has rushed for 532 yards and five touchdowns through five games, averaging 5.6 yards per carry. Las Vegas has struggled against the run, allowing approximately 141 rushing yards per game. Cook has a favourable opportunity to surpass the 91.5-yard line, particularly if Buffalo establishes an early lead.
Las Vegas Raiders
Brock Bowers anytime touchdown (-110)
Brock Bowers leads Las Vegas with 312 receiving yards and has scored three touchdowns. He caught a touchdown against New England and should remain a primary target for Kirk Cousins against Buffalo’s vulnerable pass defence.
Ashton Jeanty Under 54.5 rushing yards (-114)
Ashton Jeanty has rushed for 291 yards through five games and managed just 27 against New England last week. He has dealt with ankle and foot injuries but participated fully in Wednesday’s practice. Las Vegas could abandon the running game if Buffalo builds an early lead, making the under an appealing selection.
Buffalo Bills
Buffalo enters Sunday averaging 32.8 points per game, tied for the NFL lead.
Allen has thrown for 1,249 yards and seven touchdowns while adding eight rushing scores.
However, the Bills have allowed at least 29 points in four of their five games, including 34 against Los Angeles.
Injuries are another concern. Offensive tackle Spencer Brown and receiver Joshua Palmer were limited Wednesday, while defensive tackle Ed Oliver remained sidelined.
Buffalo must improve defensively while containing Las Vegas’ passing attack.
Las Vegas Raiders
The Raiders face a difficult test after allowing 536 yards against New England.
Cousins has thrown for 1,269 yards and 12 touchdowns, but the offence struggled to sustain drives against the Patriots.
Jeanty managed just 27 rushing yards last week, although coach Klint Kubiak confirmed he is expected to play Sunday.
Receiver Jalen Nailor is progressing through concussion protocol, while defensive tackle Tonka Hemingway is dealing with a concussion.
Las Vegas needs better protection for Cousins and a stronger defensive performance to challenge Buffalo.
BUF
LV