Buccaneers vs. Bills Prediction, Odds & Stats - November 16, 2025

Final Score
Tampa Bay
Buccaneers
Buffalo
Bills
32
44
Tampa Bay Buccaneers
Buffalo Bills
Scoreboard 1 2 3 4 Odds
Tampa Bay Buccaneers 7-8 3 17 6 6 +45.5
Buffalo Bills 11-4 7 14 10 13 -6.5

Latest Encounters

Date Result Competition Stats Recap
12/21/25
Tampa Bay Buccaneers TB ( 7-8 )
Carolina Panthers CAR ( 8-7 )
20   -   23
NFC South
12/21/25
Buffalo Bills BUF ( 11-4 )
Cleveland Browns CLE ( 3-12 )
23   -   20
AFC East
12/14/25
Buffalo Bills BUF ( 11-4 )
New England Patriots NE ( 12-3 )
35   -   31
AFC East
12/11/25
Atlanta Falcons ATL ( 6-9 )
Tampa Bay Buccaneers TB ( 7-8 )
29   -   28
NFC South
12/07/25
New Orleans Saints NO ( 5-10 )
Tampa Bay Buccaneers TB ( 7-8 )
24   -   20
NFC South
12/07/25
Cincinnati Bengals CIN ( 5-10 )
Buffalo Bills BUF ( 11-4 )
34   -   39
AFC North
11/30/25
Buffalo Bills BUF ( 11-4 )
Pittsburgh Steelers PIT ( 9-6 )
26   -   7
AFC East
11/30/25
Arizona Cardinals ARI ( 3-12 )
Tampa Bay Buccaneers TB ( 7-8 )
17   -   20
NFC West
11/23/25
Tampa Bay Buccaneers TB ( 7-8 )
L.A. Rams Rams LAR ( 11-4 )
7   -   34
NFC South
11/20/25
Buffalo Bills BUF ( 11-4 )
Houston Texans HOU ( 10-5 )
19   -   23
AFC East

Betting Action

Line History

Matchup Details

team win loss last 10 w/l streak ats money home away total
Tampa Bay Buccaneers Tampa Bay Buccaneers
6 3 3-7 3L 5-4 0 0-0 0-0 5-4
Buffalo Bills Buffalo Bills
6 3 7-3 4W 3-5 0 0-0 0-0 4-5

Recent Meetings

date home-away ats o/u BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards TB:Total Net Yards TB:Net Rushing Yards TB:Passing Yards
11/16/2025 BUF 44 - TB 32 BUF -6 Over 45.5 414 97 317 367 202 165
08/23/2025 TB 19 - BUF 23 BUF +1.5 Over 37.5 375 105 270 241 45 196
10/26/2023 BUF 24 - TB 18 TB +10 Under 42.5 302 78 224 427 115 312
12/12/2021 TB 33 - BUF 27 TB -3 Over 53 466 173 293 488 137 351
10/22/2017 BUF 30 - TB 27 BUF -3 Over 44 447 69 378 434 173 261
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
12/21/2025 CAR 23 - TB 20 L -2.5 Under 44.5 296 169 127
12/11/2025 TB 28 - ATL 29 L -5.5 Over 43.5 476 111 365
12/07/2025 TB 20 - NO 24 L -8.5 Over 41.5 260 139 121
11/30/2025 TB 20 - ARI 17 L -3 Under 45.5 386 95 291
11/23/2025 LAR 34 - TB 7 L +7 Under 49.5 193 123 70
11/16/2025 BUF 44 - TB 32 L +6 Over 45.5 367 202 165
11/09/2025 TB 23 - NE 28 L -2.5 Over 48 435 166 269
10/26/2025 NO 3 - TB 23 W -5.5 Under 45.5 212 88 124
10/20/2025 DET 24 - TB 9 L +6 Under 55 251 41 210
10/12/2025 TB 30 - SF 19 W -2.5 Over 47 363 67 296
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
12/21/2025 CLE 20 - BUF 23 L -10 Over 41 294 160 134
12/14/2025 NE 31 - BUF 35 W -4.5 Over 49.5 385 246 139
12/07/2025 BUF 39 - CIN 34 L -6 Over 32.5 416 183 233
11/30/2025 PIT 7 - BUF 26 W -3.5 Under 47.5 166 58 108
11/20/2025 HOU 23 - BUF 19 L -5 Under 44.5 261 108 153
11/16/2025 BUF 44 - TB 32 W -6 Over 45.5 414 97 317
11/09/2025 MIA 30 - BUF 13 L -9.5 Under 48.5 370 197 173
11/02/2025 BUF 28 - KC 21 W -2.5 Under 52.5 404 141 263
10/26/2025 CAR 9 - BUF 40 W -7.5 Over 48 244 114 130
10/13/2025 ATL 24 - BUF 14 L -5.5 Under 49.5 443 210 233

Matchup Edge - Scoring Stats

avg rank edge in rank avg
23.13 15 Points Per Game 3 28.93
25.13 24 Points Allowed Per Game 15 22.93
3.6 22 1st Quarter Scoring Per Game 8 5.2
5.47 20 1st Quarter Scoring Allowed Per Game 18 5
7.93 8 2nd Quarter Scoring Per Game 11 7.4
7.4 17 2nd Quarter Scoring Allowed Per Game 25 8.87
6.8 4 3rd Quarter Scording Per Game 1 7.47
5 17 3rd Quarter Scoring Allowed Per Game 2 2.87
4.8 27 4th Quarter Scoring Per Game 2 8.87
7.27 18 4th Quarter Scoring Allowed Per Game 11 6.2
54.5 20 Red Zone Efficiency 6 64.3
315.27 23 Total Yards Per Game 3 373.07
9.61 21 Total Yards Per Play 1 12.98
4.24 18 Rushing Yards Per Play 2 5.06
32.8 16 Passing Attempts Per Game 26 28.73
9.85 19 Passing Yards Per Completion 13 10.75
1.53 10 Passing Tds Per Game 7 1.67
20.13 17 Completions Per Game 19 19.93
61.4 19 Completion % 2 69.4
89.19 19 Qb Rating 5 103.01
2.2 15 Defense Sacks Per Game 12 2.33
0.53 11 Defense Interceptions Per Game 9 0.67
1.13 11 Opponent Fumbles Per Game 12 1.2
0.27 12 Opponent Fumbles Lost Per Game 5 0.53
5.6 4 Penalties Per Game 9 6.27
43.13 6 Penalty Yards Per Game 17 52
12 3 Takeaway / Giveaway Differential 9 18
4.47 16 Yards Per Punt Return 24 3.3
24.58 27 Yards Per Kickoff Return 3 28

Odds Analysis

Team Rankings

offence
Tampa Bay Buccaneers TB
Season stats rank
Total Yards 315.3 23
Passing Yards 198.33 22
Rushing Yards 116.93 20
Points Scored 23.13 18
Field Goal % 0.88 14
Buffalo Bills BUF
Season stats rank
Total Yards 373.1 3
Passing Yards 214.2 18
Rushing Yards 158.87 1
Points Scored 28.93 3
Field Goal % 0.9 8
defence
Tampa Bay Buccaneers TB
Season stats rank
Total Yards 315.3 23
Passing Yards 198.33 22
Rushing Yards 116.93 20
Points Scored 23.13 18
Field Goal % 0.88 14
Buffalo Bills BUF
Season stats rank
Total Yards 373.1 3
Passing Yards 214.2 18
Rushing Yards 158.87 1
Points Scored 28.93 3
Field Goal % 0.9 8

Injuries

Tampa Bay Buccaneers TB
Buffalo Bills BUF

National Football Conference Standings

American Football Conference Standings

Line Up - Last Game

Pitchers
POS Player
Hitters
POS Player
Pitchers
POS Player
Hitters
POS Player