Eagles vs. Bills Prediction, Odds & Stats - December 28, 2025

Scoreboard	1	2	3	4	Odds
Philadelphia Eagles 11-6	7	6	0	0	+45
Buffalo Bills 12-5	0	0	0	12	-3

Date	Result	Competition
01/17/26	Buffalo Bills BUF ( 12-5 ) Denver Broncos DEN ( 14-3 ) 30 - 33	AFC East
01/11/26	San Francisco 49ers SF ( 12-5 ) Philadelphia Eagles PHI ( 11-6 ) 23 - 19	NFC West
01/11/26	Buffalo Bills BUF ( 12-5 ) Jacksonville Jaguars JAC ( 13-4 ) 27 - 24	AFC East

Philadelphia Eagles PHI Buffalo Bills BUF

	Stat
10	Games Won	11
5	Games Lost	4
6-4	Last 10	7-3
0-0	W L Streak	0-0
9-6	Against The Spread	6-8
0	Money	0
0-0	Home	0-0
0-0	Away	0-0
7-8	Total	8-7

date	home-away	ats	o/u	BUF:Total Net Yards	BUF:Net Rushing Yards	BUF:Passing Yards	PHI:Total Net Yards	PHI:Net Rushing Yards	PHI:Passing Yards
12/28/2025	BUF 12 - PHI 13	PHI +2.5	Under 44.5	331	120	211	190	82	108
11/26/2023	PHI 37 - BUF 34	PHI -3	Over 48.5	505	173	332	378	185	193
10/27/2019	BUF 13 - PHI 31	PHI +1	Over 43.5	371	218	153	253	98	155
08/17/2017	PHI 20 - BUF 16	PHI -4	Under 39	408	136	272	329	66	263

date	score	ats	o/u	Total Net Yards	Net Rushing Yards	Passing Yards
01/11/2026	PHI 19 - SF 23	L -5.5	Under 46.5	361	75	286
01/04/2026	PHI 17 - WAS 24	L -3	Over 38.5	274	143	131
12/28/2025	BUF 12 - PHI 13	W +2.5	Under 44.5	190	82	108
12/20/2025	WAS 18 - PHI 29	W -6	Over 43.5	385	207	178
12/14/2025	PHI 31 - LV 0	W -13.5	Under 37	75	46	29
12/08/2025	LAC 22 - PHI 19	L -2.5	Over 40.5	365	134	231
11/28/2025	PHI 15 - CHI 24	L -6.5	Under 43.5	425	281	144
11/23/2025	DAL 24 - PHI 21	L -3	Under 47.5	339	63	276
11/16/2025	PHI 16 - DET 9	W -2.5	Under 46.5	317	74	243
11/10/2025	GB 7 - PHI 10	W +2.5	Under 45.5	294	111	183

date	score	ats	o/u	Total Net Yards	Net Rushing Yards	Passing Yards
01/17/2026	DEN 33 - BUF 30	L +1.5	Over 46.5	349	70	279
01/11/2026	JAC 24 - BUF 27	W -1	Under 51.5	359	154	205
01/04/2026	BUF 35 - NYJ 8	W -13	Over 39	470	211	259
12/28/2025	BUF 12 - PHI 13	L -2.5	Under 44.5	331	120	211
12/21/2025	CLE 20 - BUF 23	L -10	Over 41	294	160	134
12/14/2025	NE 31 - BUF 35	W -4.5	Over 49.5	385	246	139
12/07/2025	BUF 39 - CIN 34	L -6	Over 32.5	416	183	233
11/30/2025	PIT 7 - BUF 26	W -3.5	Under 47.5	166	58	108
11/20/2025	HOU 23 - BUF 19	L -5	Under 44.5	261	108	153
11/16/2025	BUF 44 - TB 32	W -6	Over 45.5	414	97	317

Philadelphia Eagles PHI

	Season stats	rank
Total Yards	314.2	13
Passing Yards	189.76	9
Rushing Yards	124.41	22
Points Scored	19.12	5
Field Goal %	0.83	12

Buffalo Bills BUF

	Season stats	rank
Total Yards	293.1	7
Passing Yards	156.94	1
Rushing Yards	136.18	28
Points Scored	21.47	12
Field Goal %	0.92	28

Philadelphia Eagles PHI

	Season stats	rank
Total Yards	311.2	23
Passing Yards	194.29	23
Rushing Yards	116.94	18
Points Scored	22.29	19
Field Goal %	0.74	31

Buffalo Bills BUF

	Season stats	rank
Total Yards	376.3	4
Passing Yards	216.65	15
Rushing Yards	159.65	1
Points Scored	28.29	4
Field Goal %	0.9	8

Philadelphia Eagles PHI

player (position)	status		ats*current	o/u*	notes
Jaelan Phillips (LB)	Questionable	Ankle - 02 / 01 / 26	1-1	1-1	Details
Jalen Carter (DT)	Ques Jan. 11	Hip - 02 / 01 / 26	1-1	1-1	Details
Dallas Goedert (TE)	Ques Jan. 11	Knee - 02 / 01 / 26	1-1	1-1	Details
Michael Carter II (CB)	Ques Sun	Hip - 01 / 01 / 26	1-1	1-1	Details
Marcus Epps (DB)	Ques Jan. 11	Concussion - 01 / 01 / 26	1-1	1-1	Details
Nakobe Dean (LB)	Ques Jan. 11	Hamstring - 26 / 12 / 25	2-1	2-1	Details
A.J. Brown (WR)	Ques Dec 28	Teeth - 25 / 12 / 25	2-1	2-1	Details
Fred Johnson (OT)	Questionable	Ankle - 12 / 12 / 25	3-2	3-2	Details
Landon Dickerson (G)	Questionable	Illness - 11 / 12 / 25	3-2	3-2	Details
Jaelan Phillips (LB)	Ques Dec 8	Concussion - 05 / 12 / 25	3-3	3-3	Details

Buffalo Bills BUF

player (position)	status		ats*current	o/u*	notes
Shaq Thompson (LB)	Ques Sat	Neck - 15 / 01 / 26	1-0	0-1	Details
Josh Allen (QB)	Ques Sat	Foot - 14 / 01 / 26	1-0	0-1	Details
Greg Rousseau (DE)	Ques Sat	Back - 14 / 01 / 26	1-0	0-1	Details
A.J. Epenesa (DE)	Ques Sat	Neck - 14 / 01 / 26	1-0	0-1	Details
Matt Milano (LB)	Ques Sat	Ankle - 14 / 01 / 26	1-0	0-1	Details
Landon Jackson (DE)	Out indefinitely	Knee - 14 / 01 / 26	1-0	0-1	Details
Dalton Kincaid (TE)	Ques Sat	Leg - 13 / 01 / 26	1-0	0-1	Details
Tyrell Shavers (WR)	Out Sat	Knee - 13 / 01 / 26	1-0	0-1	Details
Jordan Poyer (DB)	Out Sat	Hamstring - 13 / 01 / 26	1-0	0-1	Details
Gabe Davis (WR)	Out indefinitely	Knee - 13 / 01 / 26	1-0	0-1	Details

Philadelphia Eagles PHI

Eagles are 0-4 ATS in their last 4 games as a road underdog of 3.5-10.0.

Eagles are 4-1 ATS in their last 5 games following a ATS win.

Eagles are 4-0 ATS in their last 4 games as a road underdog.

Eagles are 10-4 ATS in their last 14 road games.

Eagles are 0-4 ATS in their last 4 games as a road favorite of 10.5 or greater.

Buffalo Bills BUF

Under is 4-1 in Bills last 5 games as a home underdog of 3.5-10.0.

Bills are 4-1 ATS in their last 5 games as a home underdog of 0.5-3.0.

Over is 4-0 in Bills last 4 games as a favorite of 10.5 or greater.

Over is 4-0 in Bills last 4 games in December.

Bills are 6-2-1 ATS in their last 9 games as a home favorite of 0.5-3.0.

Team	Win / Loss	ATS	OU
N.Y. Giants Giants NYG	4-13	8-8	10-6
Chicago Bears CHI	10-6	11-6	9-8-1
L.A. Rams Rams LAR	12-5	12-7	11-8
Tampa Bay Buccaneers TB	8-9	5-11	8-8
Philadelphia Eagles PHI	11-6	10-7	8-9
Green Bay Packers GB	9-6	6-10	9-8
San Francisco 49ers SF	12-5	11-6	10-8
Arizona Cardinals ARI	3-14	7-9	9-7
Seattle Seahawks SEA	14-3	14-5	11-8
Dallas Cowboys DAL	7-9	7-9	12-4
Minnesota Vikings MIN	9-8	8-8	8-8
Detroit Lions DET	9-8	7-9	10-6
Atlanta Falcons ATL	8-9	9-7	8-7-1
Carolina Panthers CAR	8-9	10-7	7-10
New Orleans Saints NO	6-11	8-8	5-11
Washington Commanders WAS	5-12	6-10	9-6-1

Team	Win / Loss	ATS	OU
Baltimore Ravens BAL	8-9	6-9	10-6
Denver Broncos DEN	14-3	9-9	8-10
Miami Dolphins MIA	7-10	8-8	8-6-2
Houston Texans HOU	12-5	10-8	6-12
Cleveland Browns CLE	5-12	7-9	8-8
Pittsburgh Steelers PIT	10-7	9-8	9-7-1
New England Patriots NE	14-3	14-6	12-8
Tennessee Titans TEN	3-14	5-11	10-6
L.A. Chargers Chargers LAC	11-6	9-8	8-9
Indianapolis Colts IND	8-9	8-8	8-8
N.Y. Jets Jets NYJ	3-14	7-9	10-6
Cincinnati Bengals CIN	6-11	8-8	9-7
Buffalo Bills BUF	12-5	8-9	9-9
Las Vegas Raiders LV	3-14	6-10	8-8
Jacksonville Jaguars JAC	13-4	12-5	10-7
Kansas City Chiefs KC	6-11	6-10	4-12

Philadelphia Eagles

Pitchers

POS	Player

Hitters

POS	Player

Buffalo Bills

Pitchers

POS	Player

Hitters

POS	Player

Game Statistics

190

331

Total Yards

108

211

Passing Yards

120

Rushing Yards

Touchdowns

100

Field Goal %

Turnovers

Team	Last 5 Matches
Philadelphia Eagles PHI ( 11-6 )	L L W W W
Buffalo Bills BUF ( 12-5 )	W W L W W

James Cook III Running Back Philadelphia	14	Touchdowns	11	Dallas Goedert Tight End Buffalo
James Cook III Running Back Philadelphia	1621	Rushing	1140	Saquon Barkley Running Back Buffalo
Josh Allen Quarterback Philadelphia	3668	Passing	3224	Jalen Hurts Quarterback Buffalo
A.J. Brown Wide Receiver Buffalo	78	Receiving	72	Khalil Shakir Wide Receiver Philadelphia
Greg Rousseau Defensive End Philadelphia	7	Sacks	6.5	Jalyx Hunt Linebacker Buffalo
Cole Bishop Safety Philadelphia	3	Interceptions	3	Jalyx Hunt Linebacker Buffalo

Dalton Kincaid Tight End Philadelphia	2	Touchdowns	2	Dallas Goedert Tight End Buffalo
James Cook III Running Back Philadelphia	163	Rushing	106	Saquon Barkley Running Back Buffalo
Josh Allen Quarterback Philadelphia	556	Passing	168	Jalen Hurts Quarterback Buffalo
Khalil Shakir Wide Receiver Philadelphia	19	Receiving	8	DeVonta Smith Wide Receiver Buffalo
Greg Rousseau Defensive End Philadelphia	1	Sacks	1	Jalen Carter Defensive Tackle Buffalo
Quinyon Mitchell Cornerback Buffalo	2	Interceptions	1	Cole Bishop Safety Philadelphia

team	w games_won	l games_lost	t games_tied	pf points
Arizona Cardinals ARI	0	0	0	0
L.A. Rams Rams LAR	0	0	0	0
San Francisco 49ers SF	0	0	0	0
Seattle Seahawks SEA	0	0	0	0
Atlanta Falcons ATL	0	0	0	0
Carolina Panthers CAR	0	0	0	0
New Orleans Saints NO	0	0	0	0
Tampa Bay Buccaneers TB	0	0	0	0
Dallas Cowboys DAL	0	0	0	0
N.Y. Giants Giants NYG	0	0	0	0
Philadelphia Eagles PHI	0	0	0	0
Washington Commanders WAS	0	0	0	0
Chicago Bears CHI	0	0	0	0
Detroit Lions DET	0	0	0	0
Green Bay Packers GB	0	0	0	0
Minnesota Vikings MIN	0	0	0	0

Game Preview

Eagles vs. Bills Point Spread: NFL Week 17 Odds, Prediction

The last NFL Sunday of 2025 brings us 10 big games, including an intra-conference battle between the Philadelphia Eagles and Buffalo Bills.

Team	Win / Loss	ATS	OU
N.Y. Giants Giants NYG	4-13	8-8	10-6
Chicago Bears CHI	10-6	11-6	9-8-1
L.A. Rams Rams LAR	12-5	12-7	11-8
Tampa Bay Buccaneers TB	8-9	5-11	8-8
Philadelphia Eagles PHI	11-6	10-7	8-9
Green Bay Packers GB	9-6	6-10	9-8
San Francisco 49ers SF	12-5	11-6	10-8
Arizona Cardinals ARI	3-14	7-9	9-7
Seattle Seahawks SEA	14-3	14-5	11-8
Dallas Cowboys DAL	7-9	7-9	12-4
Minnesota Vikings MIN	9-8	8-8	8-8
Detroit Lions DET	9-8	7-9	10-6
Atlanta Falcons ATL	8-9	9-7	8-7-1
Carolina Panthers CAR	8-9	10-7	7-10
New Orleans Saints NO	6-11	8-8	5-11
Washington Commanders WAS	5-12	6-10	9-6-1

Team	Win / Loss	ATS	OU
Baltimore Ravens BAL	8-9	6-9	10-6
Denver Broncos DEN	14-3	9-9	8-10
Miami Dolphins MIA	7-10	8-8	8-6-2
Houston Texans HOU	12-5	10-8	6-12
Cleveland Browns CLE	5-12	7-9	8-8
Pittsburgh Steelers PIT	10-7	9-8	9-7-1
New England Patriots NE	14-3	14-6	12-8
Tennessee Titans TEN	3-14	5-11	10-6
L.A. Chargers Chargers LAC	11-6	9-8	8-9
Indianapolis Colts IND	8-9	8-8	8-8
N.Y. Jets Jets NYJ	3-14	7-9	10-6
Cincinnati Bengals CIN	6-11	8-8	9-7
Buffalo Bills BUF	12-5	8-9	9-9
Las Vegas Raiders LV	3-14	6-10	8-8
Jacksonville Jaguars JAC	13-4	12-5	10-7
Kansas City Chiefs KC	6-11	6-10	4-12

Eagles vs. Bills Prediction, Odds & Stats December 28, 2025

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