Eagles vs. Bills Prediction, Odds & Stats - December 28, 2025

Game Scheduled
Philadelphia
Eagles
W W L L L
Buffalo
Bills
W W W L W
VS
Philadelphia Eagles
Buffalo Bills
Scoreboard Spread Moneyline O/U
Philadelphia Eagles 10-5 Philadelphia Eagles +1.5 (-115) on Sports Interaction Philadelphia Eagles +105 on Sports Interaction 44 (-110) on Sports Interaction
Buffalo Bills 11-4 Buffalo Bills -1.5 (-105) on Sports Interaction Buffalo Bills -125 on Sports Interaction 44 (-110) on Sports Interaction

Latest Encounters

Date Result Competition Stats Recap
12/21/25
Buffalo Bills BUF ( 11-4 )
Cleveland Browns CLE ( 3-12 )
23   -   20
AFC East
12/20/25
Philadelphia Eagles PHI ( 10-5 )
Washington Commanders WAS ( 4-12 )
29   -   18
NFC East
12/14/25
Las Vegas Raiders LV ( 2-13 )
Philadelphia Eagles PHI ( 10-5 )
0   -   31
AFC West
12/14/25
Buffalo Bills BUF ( 11-4 )
New England Patriots NE ( 12-3 )
35   -   31
AFC East
12/08/25
Philadelphia Eagles PHI ( 10-5 )
L.A. Chargers Chargers LAC ( 11-4 )
19   -   22
NFC East
12/07/25
Cincinnati Bengals CIN ( 5-10 )
Buffalo Bills BUF ( 11-4 )
34   -   39
AFC North
11/30/25
Buffalo Bills BUF ( 11-4 )
Pittsburgh Steelers PIT ( 9-6 )
26   -   7
AFC East
11/28/25
Chicago Bears CHI ( 11-4 )
Philadelphia Eagles PHI ( 10-5 )
24   -   15
NFC North
11/23/25
Philadelphia Eagles PHI ( 10-5 )
Dallas Cowboys DAL ( 7-8 )
21   -   24
NFC East
11/20/25
Buffalo Bills BUF ( 11-4 )
Houston Texans HOU ( 10-5 )
19   -   23
AFC East
11/16/25
Detroit Lions DET ( 8-7 )
Philadelphia Eagles PHI ( 10-5 )
9   -   16
NFC North
11/16/25
Tampa Bay Buccaneers TB ( 7-8 )
Buffalo Bills BUF ( 11-4 )
32   -   44
NFC South

Betting Action

Spread Bets • 1.5
Philadelphia Eagles PHI
0%
Buffalo Bills BUF
0%
Totals (O/U) • 44
Over 0%
Under 0%
Money Bets •
Philadelphia Eagles PHI
33%
Buffalo Bills BUF
67%

Line History

Matchup Details

team win loss last 10 w/l streak ats money home away total
Philadelphia Eagles Philadelphia Eagles
10 5 6-4 2W 9-6 0 0-0 0-0 7-8
Buffalo Bills Buffalo Bills
11 4 7-3 4W 6-8 0 0-0 0-0 8-7

Recent Meetings

date home-away ats o/u BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards PHI:Total Net Yards PHI:Net Rushing Yards PHI:Passing Yards
11/26/2023 PHI 37 - BUF 34 PHI -3 Over 48.5 505 173 332 378 185 193
10/27/2019 BUF 13 - PHI 31 PHI +1 Over 43.5 371 218 153 253 98 155
08/17/2017 PHI 20 - BUF 16 PHI -4 Under 39 408 136 272 329 66 263
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
12/20/2025 WAS 18 - PHI 29 W -6 Over 43.5 385 207 178
12/14/2025 PHI 31 - LV 0 W -13.5 Under 37 75 46 29
12/08/2025 LAC 22 - PHI 19 L -2.5 Over 40.5 365 134 231
11/28/2025 PHI 15 - CHI 24 L -6.5 Under 43.5 425 281 144
11/23/2025 DAL 24 - PHI 21 L -3 Under 47.5 339 63 276
11/16/2025 PHI 16 - DET 9 W -2.5 Under 46.5 317 74 243
11/10/2025 GB 7 - PHI 10 W +2.5 Under 45.5 294 111 183
10/26/2025 PHI 38 - NYG 20 W -10.5 Over 43.5 246 68 178
10/19/2025 MIN 22 - PHI 28 W -2.5 Over 44 361 45 316
10/09/2025 NYG 34 - PHI 17 L -7.5 Over 41.5 339 73 266
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
12/21/2025 CLE 20 - BUF 23 L -10 Over 41 294 160 134
12/14/2025 NE 31 - BUF 35 W -4.5 Over 49.5 385 246 139
12/07/2025 BUF 39 - CIN 34 L -6 Over 32.5 416 183 233
11/30/2025 PIT 7 - BUF 26 W -3.5 Under 47.5 166 58 108
11/20/2025 HOU 23 - BUF 19 L -5 Under 44.5 261 108 153
11/16/2025 BUF 44 - TB 32 W -6 Over 45.5 414 97 317
11/09/2025 MIA 30 - BUF 13 L -9.5 Under 48.5 370 197 173
11/02/2025 BUF 28 - KC 21 W -2.5 Under 52.5 404 141 263
10/26/2025 CAR 9 - BUF 40 W -7.5 Over 48 244 114 130
10/13/2025 ATL 24 - BUF 14 L -5.5 Under 49.5 443 210 233

Matchup Edge - Scoring Stats

avg rank edge in rank avg
23.27 14 Points Per Game 4 28.93
19.27 3 Points Allowed Per Game 14 22.93
6.4 2 1st Quarter Scoring Per Game 9 5.2
4.2 11 1st Quarter Scoring Allowed Per Game 18 5
6.33 18 2nd Quarter Scoring Per Game 10 7.4
4.93 3 2nd Quarter Scoring Allowed Per Game 25 8.87
4.67 17 3rd Quarter Scording Per Game 1 7.47
3.4 5 3rd Quarter Scoring Allowed Per Game 2 2.87
5.87 21 4th Quarter Scoring Per Game 2 8.87
6.53 14 4th Quarter Scoring Allowed Per Game 11 6.2
71.8 1 Red Zone Efficiency 5 64.3
319.6 22 Total Yards Per Game 4 373.07
11.15 9 Total Yards Per Play 1 12.98
4.22 20 Rushing Yards Per Play 2 5.06
28.67 28 Passing Attempts Per Game 27 28.73
10.45 16 Passing Yards Per Completion 13 10.75
1.6 8 Passing Tds Per Game 7 1.67
18.93 26 Completions Per Game 19 19.93
66.0 12 Completion % 2 69.4
100.41 6 Qb Rating 5 103.01
2.07 15 Defense Sacks Per Game 11 2.33
0.4 12 Defense Interceptions Per Game 8 0.67
1 9 Opponent Fumbles Per Game 12 1.2
0.53 5 Opponent Fumbles Lost Per Game 5 0.53
7 14 Penalties Per Game 9 6.27
60.93 28 Penalty Yards Per Game 17 52
14 6 Takeaway / Giveaway Differential 10 18
3.4 22 Yards Per Punt Return 24 3.3
23.76 29 Yards Per Kickoff Return 3 28

Odds Analysis

Team Rankings

offence
Philadelphia Eagles PHI
Season stats rank
Total Yards 319.6 22
Passing Yards 197.87 23
Rushing Yards 121.73 16
Points Scored 23.27 17
Field Goal % 0.71 32
Buffalo Bills BUF
Season stats rank
Total Yards 373.1 4
Passing Yards 214.2 18
Rushing Yards 158.87 1
Points Scored 28.93 4
Field Goal % 0.9 8
defence
Philadelphia Eagles PHI
Season stats rank
Total Yards 319.6 22
Passing Yards 197.87 23
Rushing Yards 121.73 16
Points Scored 23.27 17
Field Goal % 0.71 32
Buffalo Bills BUF
Season stats rank
Total Yards 373.1 4
Passing Yards 214.2 18
Rushing Yards 158.87 1
Points Scored 28.93 4
Field Goal % 0.9 8

Injuries

Philadelphia Eagles PHI
Buffalo Bills BUF

National Football Conference Standings

American Football Conference Standings

Line Up - Last Game

Pitchers
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Hitters
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Pitchers
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Hitters
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