How to Bet Week 9 of the 2025 NFL Season: Is it a possible AFC Championship preview in Buffalo?

As the NFL nears the halfway point of the 2025 season, playoff teams and real Super Bowl contenders are starting to emerge.

We’re back with picks and predictions for all the Week 9 prime-time games and couple Sunday afternoon matinees.

Here’s everything you need to know to bet Week 9 of the 2025 NFL season.

Sports Interaction

Pick
Odds
HomeTeam
Moneyline
NFL • Kansas City Chiefs @ Buffalo Bills
115 on Sports Interaction
CLOSED • 11/02/2025
Tally (Win %)
2-4-0 (33%)
Money Meter
$-19.41
ROI
-32.4%
Betslip #1761766065404-53c6-511

Make sure to check out Sports Interaction’s complete list of NFL game oddsNFL futures and NFL specials and props.

TNF Ravens at Dolphins

The trends all point to this being a high scoring game at Hard Rock Stadium.

The Over has hit in nine straight Dolphins home games and the offence has scored at least 27 points in eight straight at home, including all three home dates this season.

Another key point is both defences are terrible, with Miami ranking 23rd overall and 28th against the rush, while Baltimore is 28th both overall and against the pass and 23rd against the rush.

The Ravens have also trended toward higher scoring games, with the Over hitting in six of seven this season.

The four games Lamar Jackson has played this year have totalled at least 57 combined points, with an average of 66. In fact, Baltimore has scored 30 or more points in seven of Lamar Jackson’s last eight regular season starts.

Pick: Over 50.5

Colts at Steelers

Raise your hand if you expected Daniel Jones to be a legitimate MVP candidate after leading the Colts to a 7-1 record to start the year. You won’t see my hand raised.

I’ll ride with Indy in this spot spot against a Steelers team that took a big L on the field last week against Green Bay and an even bigger L in the jersey department. Seriously, look up Pittsburgh’s Week 8 uniforms, but don’t do it if you’re eating.

The Colts’ offence is torching opponents, scoring 30 or more points in four straight games and six of eight on the season. Indianapolis leads the NFL in total yards (385.3) and points per game (33.8) while ranking sixth in both passing yards (250.9) and rushing yards per game (134.4).

Meanwhile, the Steelers defence has been one of the worst units in the league, ranking 30th overall and dead last against the pass. Pittsburgh has allowed 30 or more points four times this season, including giving up 35 against the Packers last week and 33 against the Bengals two weeks ago.

Pick: Colts -3

Chiefs at Bills

Almost everyone seems to be predicting a Bills vs. Chiefs AFC Championship matchup, so this is a huge measuring stick game in Western New York.

Buffalo is the play for me this week. While Kansas City has won in the playoffs when it matters most, the Bills have actually been fairly dominant in regular season action, going 4-1 both straight up and against the spread in regular season head-to-heads since 2020.

I’m also expecting Buffalo to be the more rested and prepared team. The Chiefs just played on Monday Night Football and with the Bills facing the brutal Panthers team in Week 8, I expect they looked past Carolina and started game planning for KC during their Week 7 bye.

The Chiefs’ defence has been solid this season, but they have a weak spot at stopping the run. Buffalo running back James Cook just torched the Panthers for 216 rushing yards and two TDs and he’ll be tough for Kansas City to contain.

Pick: Bills moneyline

SNF Seahawks at Commanders

The Seahawks are in a tight race with the Rams and 49ers for control of the NFC West as they look for a third straight win on Sunday Night Football when they face the struggling Washington Commanders.

I don’t see this being a high scoring game, mostly because of Seattle. The Seahawks are one of the most run-heavy offences in the NFL and they also boast a top-10 defence capable of shutting Washington down.

Seattle has two legitimate rushing threats in Kenneth Walker III and Zach Charbonnet, which leads them to run the ball at the second-highest rate in the league, handing it off on almost half of their snaps.

The Commanders are also susceptible against the rush. Washington is allowing 5.1 yards per carry over their last three games and they just gave up 148 rushing yards to Kansas City last week.

I think this will be a run-heavy game and my rule of thumb for run-heavy games is bet the under.

Pick: Under 47.5

MNF Cardinals at Cowboys

The Dallas Cowboys return home looking to get back to .500 on the year as they prepare to face a bad Arizona Cardinals squad on Monday Night Football.

Dallas has been night and day at home versus the road this season. The Cowboys are 2-0-1 at AT&T Stadium compared to 1-4 on the road.

On the flip side, Arizona struggles everywhere, posting just one home win and one road win this season.

The Cardinals have one of the worst passing defences in the league, which some people might view as concerning considering Dallas averages an NFL-best 263.8 passing yards per game.

I’m rolling with Dak Prescott and co. to win big in a high scoring game.

Pick: Cowboys -2.5, Over 54

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