NFL Point Spreads Week 7: Best Picks Against the Spread

Payton Matthews | Updated Oct 18, 2018


Week 7 brings a first in the 2018 NFL season: More than two teams on the bye. The four off are Green Bay, Seattle, Oakland and Pittsburgh.

Here’s a quick look at all the Week 7 matchups with Sports Interaction’s NFL betting odds. Games Sunday unless noted.

Denver Broncos at Arizona Cardinals, Thursday

We are trying to be glass half-full here and think of something positive about this rather unappealing Thursday night matchup. OK, here’s two: It should be close and you can bet on it here at Sports Interaction! Don’t expect much offence, though. Arizona is wretched on that side of the ball. Here’s our full preview of the Broncos vs. Cardinals game.

Point spread: Broncos -1.5

Pick ATS: Arizona

Tennessee Titans at Los Angeles Chargers

This game from Wembley Stadium in London and with a 9:30 a.m. ET start. Seems especially unfair to the Chargers players as that means 6:30 ET Pacific time. Los Angeles won its third in a row Sunday, 38-14 in Cleveland. Melvin Gordon rushed for three scores. Instead of flying back to L.A. and then overseas, the team is staying in Cleveland before leaving Thursday for London. The Titans’ offensive woes continued in a 21-0 home loss to Baltimore. QB Marcus Mariota was sacked 11 times. Here’s our extended preview of this matchup.

Point spread: Chargers -6.5

Pick ATS: LA Chargers

New England Patriots at Chicago Bears

The Bears could have and should have won Sunday in Miami but found inventive ways to lose 31-28 in overtime out of their bye, easily the team’s worst defensive effort of the season. The Bears were favored by nearly a touchdown on the road on for the first time since 2010. New England handed Kansas City its first loss Sunday night in the first-ever NFL game to end with a score of 43-40. Tom Brady threw for 340 yards and a score and had a rare rushing TD. Sports Interaction’s full preview of this matchup is here.

Point spread: Patriots -3.5

Pick ATS: New England

Buffalo Bills at Indianapolis Colts

The Bills lost rookie quarterback Josh Allen to injury Sunday in Houston and watched as horrible backup Nathan Peterman threw two interceptions in his place, including the game-losing pick-six late in the fourth quarter. Too early to tell if Allen can play here. The Colts are really banged up and lost their fourth straight Sunday, 42-34 at the Jets. Andrew Luck can’t do it all by himself. Get more betting details on this matchup here.

Point spread: Colts -6.5

Pick ATS: Indianapolis

Detroit Lions at Miami Dolphins

The Lions come off their bye and are really hard to judge. They have beaten very good teams in the Patriots and Packers and also lost to bad teams like the Jets and 49ers. Miami surprisingly scratched starting QB Ryan Tannehill on Sunday due to a shoulder injury that seemed to come out of nowhere and upset the Bears 31-28 in overtime in a very wild game. Brock Osweiler had a big day in Tannehill’s spot. Not clear yet if Tannehill plays here. Click here for Sports Interaction’s complete betting preview of this game.

Point spread: Dolphins -4

Pick ATS: Detroit

Minnesota Vikings at New York Jets

Minnesota won its second in a row Sunday, 27-17 over visiting Arizona. With top running back Dalvin Cook out injured, Latavius Murray picked up the slack with 155 yards and a score on 24 carries. Adam Thielen had his sixth straight 100-yard game to open the season. The Jets won their second in a row Sunday, 42-34 over the Colts. Jason Myers kicked a franchise-record seven field goals. Our full betting preview to the Vikings vs. Jets game is right here.

Point spread: Vikings -3

Pick ATS: Minnesota

Carolina Panthers at Philadelphia Eagles

Carolina welcomed back two very important pieces in linebacker Thomas Davis (suspension) and tight end Greg Olsen (broken foot) but lost in Washington on Sunday largely due to three turnovers. Philadelphia is on extra rest after spanking the Giants on Thursday night in easily the Eagles’ best game of the season. For more on this game, click here.

Point spread: Eagles -4

Pick ATS: Philadelphia

Cleveland Browns at Tampa Bay Buccaneers

It’s two of the franchises in the NFL that have had winless seasons! It’s also former No. 1 overall picks and Heisman winners facing off in Browns QB Baker Mayfield and Bucs counterpart Jameis Winston. Cleveland is much improved this year but didn’t look like it Sunday in a 38-14 home loss to the Chargers. Tampa Bay’s defence is pitiful this year and it allowed 34 more points in a loss in Atlanta. Check out our complete betting preview of Browns vs. Bucs here.

Point spread: Bucs -3

Pick ATS: Tampa Bay

Houston Texans at Jacksonville Jaguars

These teams are tied for first in the mediocre AFC South at 3-3 along with Tennessee. The Texans won a third consecutive game Sunday, 20-13 over Buffalo. Jonathan Joseph returned an interception 28 yards for a score with just over a minute left. Jacksonville’s once-vaunted defence has been ripped apart in a two-game skid, allowing 70 combined points. Click here for our full preview of the Texans vs. Jaguars game. Click here for the full preview of this game.

Point spread: Jaguars -4.5

Pick ATS: Jacksonville

New Orleans Saints at Baltimore Ravens

The Saints are off their bye and atop the NFC South. Drew Brees became the NFL’s all-time passing yardage leader in New Orleans’ Week 5 win over Washington, and he should become the fourth member of the 500 TD passing club here. Baltimore set a franchise record with 11 sacks Sunday in a 21-0 win at Tennessee. This is the Ravens’ first home game in nearly a month. Sports Interaction’s complete preview of this game is here.

Point spread: Ravens -2.5

Pick ATS: Baltimore

Los Angeles Rams at San Francisco 49ers

If you have an NFL schedule printed from this summer, you will see this game was to be played on Sunday night. However, NBC wanted no part of the 49ers so this was “flexed” out. The Rams are the NFL’s lone unbeaten following a 23-20 win in snowy Denver on Sunday. It’s a short week for the Niners after playing Monday in Green Bay. Click here for our full betting guide to this game between the Rams and the 49ers.

Point spread: TBA (likely Rams -11)

Pick ATS: San Francisco

Dallas Cowboys at Washington Redskins

The Cowboys are just a different team at home than on the road as they are 0-3 away from Big D and improved to 3-0 there with Sunday’s 40-7 wipeout of the Jaguars. Cole Beasley caught two touchdown passes from Dak Prescott. Washington looked horrific last Monday in a loss in New Orleans but rebounded with a 23-17 home win over Carolina on Sunday. Here’s our extended preview of the Cowboys vs. Redskins game.

Point spread: Redskins -2

Pick ATS: Washington

Cincinnati Bengals at Kansas City Chiefs

This game was “flexed” from the afternoon to the Sunday night matchup – the second straight SNF game for the Chiefs. The Bengals just can’t beat the Steelers these days and blew a late lead Sunday in a 28-21 home defeat vs. Pittsburgh. Kansas City’s spectacular offence hung 40 on the Patriots Sunday night but its porous defence allowed 43 in the Chiefs’ first loss of the year. Click here for our complete betting preview of this SNF matchup.

Point spread: Chiefs -6

Pick ATS: Kansas City

New York Giants at Atlanta Falcons, Monday

Hmmm, how can we be glass half-full here? Some of the best offensive players at their position in the NFL will be on the field in Falcons quarterback Matt Ryan and receiver Julio Jones, and Giants rookie running back Saquon Barkley and receiver Odell Beckham Jr. However, neither team as a whole is any good. Giants fans are tired of Eli Manning and want a change at quarterback, but Coach Pat Shurmur isn’t ready to dump the two-time Super Bowl winner yet.

Point spread: Falcons -6

Pick ATS: Atlanta

NFL Week 7 Odds and Picks ATS

Time (ET)MatchupOddsPick ATS
8:20PMDenver Broncos at Arizona CardinalsBroncos -1.5Arizona
9:30AMTennessee Titans at Los Angeles ChargersChargers -6.5LA
1:00PMNew England Patriots at Chicago BearsPatriots -3.5New England
1:00PMBuffalo Bills at Indianapolis ColtsColts -6.5Indianapolis
1:00PMDetroit Lions at Miami DolphinsDolphins -4Detroit
1:00PMMinnesota Vikings at New York JetsVikings -3Minnesota
1:00PMCarolina Panthers at Philadelphia EaglesEagles -4Philadelphia
1:00PMCleveland Browns at Tampa Bay BuccaneersBucs -3Tampa Bay
1:00PMHouston Texans at Jacksonville JaguarsJaguars -4.5Jacksonville
4:05PMNew Orleans Saints at Baltimore RavensRavens -2.5Baltimore
4:25PMLos Angeles Rams at San Francisco 49ersTBA (likely Rams -11)San Francisco
4:25PMDallas Cowboys at Washington RedskinsRedskins -2Washington
8:20PMCincinnati Bengals at Kansas City ChiefsChiefs -6Kansas City
8:15PMNew York Giants at Atlanta Falcons, MondayFalcons -6Atlanta