The Bills may have to lean heavily again on a rush attack lead by LeSean McCoy that has produced just 597 total yards on the ground on 3.6 yards per carry.
The good news for the Indianapolis Colts is that they’ve begun to hit their offensive stride. The bad news is, not even a sudden scoring surge has moved them back into the win column as they bring a four-game losing streak into Sunday’s encounter with visiting Buffalo. The Colts have averaged better than 30 points over their previous three games but have fallen short in all three, having surrendered a whopping 39 points per game in that span.
NFL Point Spread and Betting Analysis
Line History
Sports Interaction customers are placing their bets on:
time | fav | line | total |
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Opening 17 Oct 2:18am | BUF | -7.5 -110 | O +43 -110 |
Closing 21 Oct 4:03pm | BUF | -7 -115 | O +43.5 -110 |
It has been nearly four years since Indy has been favoured by a touchdown or more – but when the Colts have given away that many points, they’ve been a really good cover option, having gone 6-1-1 ATS in their previous eight games when giving away seven or more points. The Bills put together their best game of the season away from Buffalo with a 27-6 victory over Minnesota, but scored just 19 total points in their past four road games aside from that one.
Not surprisingly, the Bills enter the weekend having been one of the more reliable under options on the road, having gone below the number in 10 of their previous 14 games outside Buffalo. The Colts have cashed the over in consecutive home games after reeling off a streak of five consecutive unders, but are 4-11 O/U in their previous 15 contests at Lucas Oil Stadium. And the under has come through in six of the past seven meetings between the teams.
Buffalo Bills
The Bills are already struggling mightily on offence, averaging a league-low 12.7 points per game – and things are even more dire with word that rookie quarterback Josh Allen will miss up to a month with an elbow injury. Look for the Bills to lean even more heavily on a rush attack lead by LeSean McCoy that has produced just 597 total yards on the ground on 3.6 yards per carry. The Colts have been surprisingly stingy against the run in 2018, limiting opponents to 3.7 yards per tote.
Indianapolis Colts
While the Colts’ defence hopes for a reprieve against the Bills’ woeful pass attack, they’d love nothing more than to see Andrew Luck continue his solid play. Luck has thrown for more than 1,100 yards over the previous three weeks while tossing 11 touchdown passes. But Luck has also thrown five interceptions over the past two weeks, giving him eight for the season – tied with Case Keenum, Blake Bortles and Derek Carr for the league lead.
Weather

temp | 44 |
condition | dome |
wind | North 3mph |
Injuries
Deonte Thompson (WR)
Patrick DiMarco (FB)
Corey Thompson (LB)
Stephen Hauschka (K)
Ryan Lewis (CB)
Isaiah McKenzie (WR)
Jason Croom (TE)
Lafayette Pitts (CB)
Russell Bodine (C)
Shaq Lawson (DE)
J.J. Wilcox (S)
Jordan Wilkins (RB)
Daurice Fountain (WR)
George Odum (S)
Skai Moore (LB)
Mark Glowinski (G)
Chester Rogers (WR)
Mo Alie-Cox (TE)
Al Woods (DT)
D.J. Killings (CB)
Injuries
player (position) | status | ats*current | o/u* | notes | |
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Deonte Thompson (WR) | Out Sun | Toe - 28 / 12 / 18 | 1-0 | 0-1 | + - |
Thompson will not take the field against the Dolphins on Sunday due to a toe injury. |
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Patrick DiMarco (FB) | Prob Sun | Ankle - 19 / 12 / 18 | 1-1 | 0-2 | + - |
DiMarco is battling an ankle injury but is expected to be available Sunday against the Patriots. |
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Corey Thompson (LB) | Prob Sun | Ankle - 19 / 12 / 18 | 1-1 | 0-2 | + - |
Thompson is hampered by an ankle injury but it is not expected to affect his status for Sunday's tilt against the Patriots. |
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Stephen Hauschka (K) | Prob Sun | Back - 10 / 12 / 18 | 1-2 | 1-2 | + - |
Hauschka missed the last game with a lower-back injury but it is anticipated that he will participate in Sunday's contest against the Patriots. |
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Ryan Lewis (CB) | Out Sun | Concussion - 10 / 12 / 18 | 1-2 | 1-2 | + - |
Lewis has missed the last two games battling a concussion and will not be able to pass the league-mandated protocol in time for Sunday's game against the Dolphins. |
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Isaiah McKenzie (WR) | Ques Sun | Toe - 06 / 12 / 18 | 1-3 | 1-3 | + - |
McKenzie is hampered by a toe injury and it is unclear if he will take the field Sunday versus the Jets. |
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Jason Croom (TE) | Prob Sun | Groin - 05 / 12 / 18 | 1-3 | 1-3 | + - |
Croom missed the last game with a groin injury but is likely to play against the Lions on Sunday. |
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Lafayette Pitts (CB) | Ques Sun | Concussion - 25 / 11 / 18 | 3-3 | 3-3 | + - |
Pitts left the last game due to a concussion and his status for Sunday's contest against the Dolphins is up in the air. |
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Russell Bodine (C) | Ques Sun | Shoulder - 21 / 11 / 18 | 3-3 | 3-3 | + - |
Bodine is battling a shoulder injury and it is undetermined if he will play Sunday against the Jaguars. |
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Shaq Lawson (DE) | Ques Sun | Elbow - 21 / 11 / 18 | 3-3 | 3-3 | + - |
Lawson has an elbow injury and it is unknown if he will play Sunday against the Jaguars. |
player (position) | status | ats*current | o/u* | notes | |
---|---|---|---|---|---|
J.J. Wilcox (S) | Prob Sat | Ankle - 03 / 01 / 19 | 2-0 | 1-1 | + - |
Wilcox missed the last game with an ankle injury but is expected to suit up against the Chiefs in the AFC divisional round. |
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Jordan Wilkins (RB) | Prob Sat | Knee - 01 / 01 / 19 | 2-0 | 1-1 | + - |
Wilkins is bothered by injuries to his knee and ankle. He is likely to line up against the Texans in the AFC wild-card round. |
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Daurice Fountain (WR) | Prob Sat | Ankle - 28 / 12 / 18 | 2-1 | 2-1 | + - |
Fountain missed the last game dealing with an ankle injury but will likely participate in the AFC wild-card round against the Texans. |
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George Odum (S) | Ques Sun | Knee - 19 / 12 / 18 | 3-1 | 2-2 | + - |
Odum hurt his knee and his status is up in the air against the Giants on Sunday. |
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Skai Moore (LB) | I-R | Neck - 13 / 12 / 18 | 4-1 | 2-3 | + - |
Moore has been placed on the injured reserve list due to a neck injury. |
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Mark Glowinski (G) | Ques Sun | Ankle - 09 / 12 / 18 | 4-2 | 2-4 | + - |
Glowinski was held out the last two games due to an ankle injury and it is unclear if he will play Sunday against the Titans. |
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Chester Rogers (WR) | Ques Sun | Groin - 30 / 11 / 18 | 4-3 | 2-5 | + - |
Rogers is dealing with a groin injury and it is unknown if he will play Sunday against the Jaguars. |
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Mo Alie-Cox (TE) | Ques Sun | Calf - 24 / 11 / 18 | 5-3 | 2-6 | + - |
Alie-Cox has missed the last three games due to a calf injury and it is uncertain if he will return to action against the Cowboys on Sunday. |
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Al Woods (DT) | Ques Sun | Illness - 21 / 11 / 18 | 5-3 | 2-6 | + - |
Woods is ailing from an illness and it is uncertain if the symptoms will subside in time for Sunday's game against the Dolphins. |
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D.J. Killings (CB) | I-R | Ankle - 15 / 11 / 18 | 5-3 | 3-6 | + - |
Killings has been placed on injured reserve with an ankle injury. |
Bills vs. Colts Prediction
-
BUFFALO BILLS
17 -
INDIANAPOLIS COLTS
24
Score
Prediction
-
Line History
Sports Interaction customers are placing their bets on:
time fav line total Opening 17 Oct 2:18am BUF -7.5 -110 O +43 -110 Closing 21 Oct 4:03pm BUF -7 -115 O +43.5 -110 -
Weather
temp 44 condition dome wind North 3mph -
Injuries
Deonte Thompson (WR)
Out Sun Toe - 28 / 12 / 18Patrick DiMarco (FB)
Prob Sun Ankle - 19 / 12 / 18Corey Thompson (LB)
Prob Sun Ankle - 19 / 12 / 18Stephen Hauschka (K)
Prob Sun Back - 10 / 12 / 18Ryan Lewis (CB)
Out Sun Concussion - 10 / 12 / 18Isaiah McKenzie (WR)
Ques Sun Toe - 06 / 12 / 18Jason Croom (TE)
Prob Sun Groin - 05 / 12 / 18Lafayette Pitts (CB)
Ques Sun Concussion - 25 / 11 / 18Russell Bodine (C)
Ques Sun Shoulder - 21 / 11 / 18Shaq Lawson (DE)
Ques Sun Elbow - 21 / 11 / 18J.J. Wilcox (S)
Prob Sat Ankle - 03 / 01 / 19Jordan Wilkins (RB)
Prob Sat Knee - 01 / 01 / 19Daurice Fountain (WR)
Prob Sat Ankle - 28 / 12 / 18George Odum (S)
Ques Sun Knee - 19 / 12 / 18Skai Moore (LB)
I-R Neck - 13 / 12 / 18Mark Glowinski (G)
Ques Sun Ankle - 09 / 12 / 18Chester Rogers (WR)
Ques Sun Groin - 30 / 11 / 18Mo Alie-Cox (TE)
Ques Sun Calf - 24 / 11 / 18Al Woods (DT)
Ques Sun Illness - 21 / 11 / 18D.J. Killings (CB)
I-R Ankle - 15 / 11 / 18Injuries
player (position) status ats*current o/u* notes Deonte Thompson (WR) Out Sun Toe - 28 / 12 / 18 1-0 0-1 + - Thompson will not take the field against the Dolphins on Sunday due to a toe injury.
Patrick DiMarco (FB) Prob Sun Ankle - 19 / 12 / 18 1-1 0-2 + - DiMarco is battling an ankle injury but is expected to be available Sunday against the Patriots.
Corey Thompson (LB) Prob Sun Ankle - 19 / 12 / 18 1-1 0-2 + - Thompson is hampered by an ankle injury but it is not expected to affect his status for Sunday's tilt against the Patriots.
Stephen Hauschka (K) Prob Sun Back - 10 / 12 / 18 1-2 1-2 + - Hauschka missed the last game with a lower-back injury but it is anticipated that he will participate in Sunday's contest against the Patriots.
Ryan Lewis (CB) Out Sun Concussion - 10 / 12 / 18 1-2 1-2 + - Lewis has missed the last two games battling a concussion and will not be able to pass the league-mandated protocol in time for Sunday's game against the Dolphins.
Isaiah McKenzie (WR) Ques Sun Toe - 06 / 12 / 18 1-3 1-3 + - McKenzie is hampered by a toe injury and it is unclear if he will take the field Sunday versus the Jets.
Jason Croom (TE) Prob Sun Groin - 05 / 12 / 18 1-3 1-3 + - Croom missed the last game with a groin injury but is likely to play against the Lions on Sunday.
Lafayette Pitts (CB) Ques Sun Concussion - 25 / 11 / 18 3-3 3-3 + - Pitts left the last game due to a concussion and his status for Sunday's contest against the Dolphins is up in the air.
Russell Bodine (C) Ques Sun Shoulder - 21 / 11 / 18 3-3 3-3 + - Bodine is battling a shoulder injury and it is undetermined if he will play Sunday against the Jaguars.
Shaq Lawson (DE) Ques Sun Elbow - 21 / 11 / 18 3-3 3-3 + - Lawson has an elbow injury and it is unknown if he will play Sunday against the Jaguars.
player (position) status ats*current o/u* notes J.J. Wilcox (S) Prob Sat Ankle - 03 / 01 / 19 2-0 1-1 + - Wilcox missed the last game with an ankle injury but is expected to suit up against the Chiefs in the AFC divisional round.
Jordan Wilkins (RB) Prob Sat Knee - 01 / 01 / 19 2-0 1-1 + - Wilkins is bothered by injuries to his knee and ankle. He is likely to line up against the Texans in the AFC wild-card round.
Daurice Fountain (WR) Prob Sat Ankle - 28 / 12 / 18 2-1 2-1 + - Fountain missed the last game dealing with an ankle injury but will likely participate in the AFC wild-card round against the Texans.
George Odum (S) Ques Sun Knee - 19 / 12 / 18 3-1 2-2 + - Odum hurt his knee and his status is up in the air against the Giants on Sunday.
Skai Moore (LB) I-R Neck - 13 / 12 / 18 4-1 2-3 + - Moore has been placed on the injured reserve list due to a neck injury.
Mark Glowinski (G) Ques Sun Ankle - 09 / 12 / 18 4-2 2-4 + - Glowinski was held out the last two games due to an ankle injury and it is unclear if he will play Sunday against the Titans.
Chester Rogers (WR) Ques Sun Groin - 30 / 11 / 18 4-3 2-5 + - Rogers is dealing with a groin injury and it is unknown if he will play Sunday against the Jaguars.
Mo Alie-Cox (TE) Ques Sun Calf - 24 / 11 / 18 5-3 2-6 + - Alie-Cox has missed the last three games due to a calf injury and it is uncertain if he will return to action against the Cowboys on Sunday.
Al Woods (DT) Ques Sun Illness - 21 / 11 / 18 5-3 2-6 + - Woods is ailing from an illness and it is uncertain if the symptoms will subside in time for Sunday's game against the Dolphins.
D.J. Killings (CB) I-R Ankle - 15 / 11 / 18 5-3 3-6 + - Killings has been placed on injured reserve with an ankle injury.