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Bills vs. Rams Prediction, Odds & Stats October 12, 2026

Game Scheduled
AFC East
Oct 12th, 8:15 PM EDT
Buffalo
Bills
L W W W W
L.A. Rams
Rams
L W L W W
VS
Buffalo Bills
Los Angeles Rams
Scoreboard Spread Moneyline O/U
Buffalo Bills 3-1 - - -
Los Angeles Rams 2-2 - - -
Loading odds...

Latest Encounters

Date Result Competition Stats Recap
10/04/26
New England Patriots NE ( 2-2 )
Buffalo Bills BUF ( 3-1 )
29   -   26
 AFC East
10/04/26
L.A. Rams Rams LAR ( 2-2 )
Philadelphia Eagles PHI ( 2-2 )
24   -   20
 NFC West
09/27/26
L.A. Rams Rams LAR ( 2-2 )
Denver Broncos DEN ( 2-2 )
26   -   30
 NFC West

Line History

Matchup Details

Buffalo Bills BUF
L.A. Rams Rams LAR
Stat
3 Games Won 2
1 Games Lost 2
3-1 Last 10 2-2
0-0 W L Streak 0-0
3-1 Against The Spread 2-2
0 Money 0
0-0 Home 0-0
0-0 Away 0-0
3-1 Total 1-3

Recent Meetings

date home-away ats o/u LAR:Total Net Yards LAR:Net Rushing Yards LAR:Passing Yards BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards
12/08/2024 LAR 44 - BUF 42 LAR +4.5 Over 51 445 103 342 457 137 320
09/08/2022 LAR 10 - BUF 31 BUF -1 Under 51.5 413 121 292 243 52 191
09/27/2020 BUF 35 - LAR 32 BUF -1.5 Over 46.5 478 167 311 375 101 274
10/09/2016 LAR 19 - BUF 30 BUF +2.5 Over 40 305 193 112 345 102 243
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
10/04/2026 BUF 26 - NE 29 L -7 Over 49.5 405 143 262
09/27/2026 BUF 24 - LAC 16 W -7 Under 50.5 348 131 217
09/17/2026 BUF 41 - DET 31 W -3 Over 52.5 355 66 289
09/13/2026 HOU 31 - BUF 36 W -1.5 Over 44.5 409 86 323
08/27/2026 BUF 28 - PIT 27 L -1 Over 35 232 97 135
08/22/2026 CLE 7 - BUF 31 W +1 Under 39.5 368 138 230
08/15/2026 BUF 29 - CAR 14 W +1 Over 38 224 61 163
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
10/04/2026 PHI 20 - LAR 24 W -2.5 Under 47 172 104 68
09/27/2026 DEN 30 - LAR 26 L -2.5 Over 45.5 257 78 179
09/21/2026 LAR 28 - NYG 6 W -7 Under 47.5 481 163 318
09/10/2026 LAR 7 - SF 27 L -2.5 Under 48.5 290 122 168
08/27/2026 LAC 18 - LAR 20 W +2.5 Under 39.5 394 204 190
08/22/2026 LAR 34 - NO 0 W +1 Under 38.5 405 151 254
08/15/2026 KC 12 - LAR 20 W +1.5 Under 36.5 314 125 189

Odds Analysis

Team Rankings

Buffalo Bills BUF
Season stats rank
Total Yards 372.3 27
Passing Yards 256.25 27
Rushing Yards 116 19
Points Scored 26.75 25
Field Goal % 0.83 12
L.A. Rams Rams LAR
Season stats rank
Total Yards 247.5 2
Passing Yards 145.5 2
Rushing Yards 102 11
Points Scored 20.75 10
Field Goal % 0.75 7
Buffalo Bills BUF
Season stats rank
Total Yards 386.3 8
Passing Yards 247.25 12
Rushing Yards 139 5
Points Scored 31.75 1
Field Goal % 1 1
L.A. Rams Rams LAR
Season stats rank
Total Yards 417 2
Passing Yards 290.25 2
Rushing Yards 126.75 7
Points Scored 21.25 19
Field Goal % 0.71 27

Injuries

Buffalo Bills BUF
L.A. Rams Rams LAR

Buffalo vs. L.A. Rams Betting News

Buffalo Vs L.A. Rams Betting Trends

Buffalo Bills BUF

Over is 5-2 in Bills last 7 games after allowing more than 350 total yards in their previous game.

Over is 4-1 in Bills last 5 games as a favorite.

Under is 4-0 in Bills last 4 games in Week 5.

Over is 5-0 in Bills last 5 games as a favorite of 10.5 or greater.

Bills are 1-4 ATS in their last 5 games as a road favorite of 10.5 or greater.

L.A. Rams Rams LAR

Over is 9-2 in Rams last 11 games as a home underdog of 3.5-10.0.

Rams are 4-1 ATS in their last 5 home games.

Under is 7-1 in Rams last 8 Monday games.

Under is 4-1 in Rams last 5 games as a favorite.

Rams are 0-4 ATS in their last 4 games following a ATS win.

American Football Conference Standings

National Football Conference Standings

Line Up - Last Game

Buffalo Bills
Pitchers
POS Player
Hitters
POS Player
Los Angeles Rams
Pitchers
POS Player
Hitters
POS Player
  • BUF
  • +3 -3
  • LAR
Odds