49ers vs. Seahawks NFL Week 5 Betting Odds, Picks: Seattle favoured by a field goal in NFL West battle
The undefeated San Francisco 49ers face a major NFC West test when they visit the Seattle Seahawks on Sunday afternoon.
San Francisco improved to 4-0 with a 24-14 victory over the Denver Broncos in Week 4. Brock Purdy threw for 218 yards and two touchdowns, while Christian McCaffrey rushed for 52 yards and a score.
Seattle improved to 3-1 with a 30-23 victory over the Los Angeles Chargers. The Seahawks bounced back after suffering their first loss of the season at Washington in Week 3.
San Francisco leads Seattle by one game atop the NFC West.
49ers vs. Seahawks Kickoff, Weather, TV, Streaming Info
Kickoff is Sunday at 4:25 p.m. ET at Lumen Field in Seattle. The game airs on FOX and streams on NFL+.
The forecast calls for sunny skies and temperatures in the upper 50sF with little chance of rain.
NFL Betting Odds, Point Spread, Trends
Seattle is currently a 3-point home favourite on the NFL odds with a -155 moneyline, while San Francisco is +130. The total is 47.5 points.
The 49ers have scored at least 24 points in all four games and lead the NFC with 122 points. Purdy has thrown for 1,007 yards, 11 touchdowns and one interception while completing nearly 70 per cent of his passes.
Seattle has scored 105 points and allowed 73 through four games. The Seahawks have won both home games this season.
NFL Player Odds and Props
San Francisco 49ers
Christian McCaffrey Over 53.5 rushing yards (-111)
McCaffrey leads San Francisco with 218 rushing yards and has scored four touchdowns. He is averaging 54.5 rushing yards per game, putting him just above this number as San Francisco looks to establish its ground game.
Brock Purdy Over 1.5 passing touchdowns (+103)
Purdy has thrown at least two touchdown passes in all four games, including four against Arizona in Week 3. He has 11 touchdowns against only one interception this season.
Seattle Seahawks
Jaxon Smith-Njigba Over 91.5 receiving yards (-113)
Jaxon Smith-Njigba has 481 receiving yards through four games, averaging 120.3 per contest. He topped 120 yards in each of Seattle’s first three games before finishing with 76 against the Chargers.
Sam Darnold Over 1.5 passing touchdowns (-111)
Sam Darnold threw two touchdown passes against the Chargers and has six through his first three appearances. San Francisco’s injuries on defence could create opportunities for Seattle’s passing attack.
San Francisco 49ers
San Francisco has been one of the NFL’s most efficient offensive teams during its perfect start. Purdy has not been sacked through four games and has thrown only one interception in 113 attempts.
The 49ers have also won six of their past eight regular-season meetings with Seattle and four straight at Lumen Field.
San Francisco will be without fullback Kyle Juszczyk, who is expected to miss several weeks with a hyperextended right knee and bone bruise. Defensive end Nick Bosa also missed Wednesday’s practice with knee and calf injuries.
Seattle Seahawks
Seattle responded well after its Week 3 loss, building a 27-6 lead against the Chargers before holding on for the victory.
Sam Darnold completed 13 of 22 passes for 168 yards, two touchdowns and an interception. Emanuel Wilson contributed a rushing touchdown and a 23-yard touchdown reception.
Smith-Njigba remains Seattle’s biggest offensive threat, while Wilson could again carry a significant workload with Zach Charbonnet unavailable.
Seattle will need to play with more discipline after being penalized 14 times for a franchise-record 150 yards against Los Angeles.
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