Sports Interaction

Patriots vs. Bills Prediction, Odds & Stats - October 05, 2025

Final Score
New England
Patriots
Buffalo
Bills
23
20
New England Patriots
Buffalo Bills
Scoreboard 1 2 3 4 Odds
New England Patriots 14-3 3 3 7 10 +49.5
Buffalo Bills 12-5 0 3 7 10 -8

Latest Encounters

Date Result Competition Stats Recap
01/18/26
Houston Texans HOU ( 12-5 )
New England Patriots NE ( 14-3 )
16   -   28
AFC South
01/17/26
Buffalo Bills BUF ( 12-5 )
Denver Broncos DEN ( 14-3 )
30   -   33
AFC East
01/11/26
L.A. Chargers Chargers LAC ( 11-6 )
New England Patriots NE ( 14-3 )
3   -   16
AFC West
01/11/26
Buffalo Bills BUF ( 12-5 )
Jacksonville Jaguars JAC ( 13-4 )
27   -   24
AFC East
01/04/26
Miami Dolphins MIA ( 7-10 )
New England Patriots NE ( 14-3 )
10   -   38
AFC East
01/04/26
N.Y. Jets Jets NYJ ( 3-14 )
Buffalo Bills BUF ( 12-5 )
8   -   35
AFC East
12/28/25
Philadelphia Eagles PHI ( 11-6 )
Buffalo Bills BUF ( 12-5 )
13   -   12
NFC East
12/28/25
New England Patriots NE ( 14-3 )
N.Y. Jets Jets NYJ ( 3-14 )
42   -   10
AFC East
12/21/25
New England Patriots NE ( 14-3 )
Baltimore Ravens BAL ( 8-9 )
28   -   24
AFC East
12/21/25
Buffalo Bills BUF ( 12-5 )
Cleveland Browns CLE ( 5-12 )
23   -   20
AFC East
12/14/25
Buffalo Bills BUF ( 12-5 )
New England Patriots NE ( 14-3 )
35   -   31
AFC East

Line History

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Matchup Details

team win loss last 10 w/l streak ats money home away total
New England Patriots New England Patriots
2 2 9-1 3W 2-2 0 0-0 0-0 2-2
Buffalo Bills Buffalo Bills
4 0 7-3 1W 1-2 0 0-0 0-0 3-1

Recent Meetings

date home-away ats o/u BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards NE:Total Net Yards NE:Net Rushing Yards NE:Passing Yards
12/14/2025 NE 31 - BUF 35 BUF -4.5 Over 49.5 349 168 181 385 246 139
10/05/2025 BUF 20 - NE 23 NE +8.5 Under 49.5 363 118 245 338 71 267
01/05/2025 NE 23 - BUF 16 NE +3 Under 40 259 130 129 309 77 232
12/22/2024 BUF 24 - NE 21 NE +14 Under 46.5 379 126 253 324 172 152
12/31/2023 BUF 27 - NE 21 NE +12 Over 40 294 103 191 281 127 154
10/22/2023 NE 29 - BUF 25 NE +8.5 Over 41 339 81 258 364 96 268
01/08/2023 BUF 35 - NE 23 BUF -8 Over 44 341 107 234 327 90 237
12/01/2022 NE 10 - BUF 24 BUF -5.5 Under 44 355 132 223 242 60 182
01/15/2022 BUF 47 - NE 17 BUF -4.5 Over 43.5 305 89 216 482 174 308
12/26/2021 NE 21 - BUF 33 BUF +1 Over 44.5 428 114 314 288 149 139
12/06/2021 BUF 10 - NE 14 NE +3 Under 41 241 222 19 230 99 131
12/28/2020 NE 9 - BUF 38 BUF -6.5 Under 47.5 474 130 344 201 145 56
11/01/2020 BUF 24 - NE 21 NE +4 Over 41 349 188 161 339 190 149
12/21/2019 NE 24 - BUF 17 NE -6.5 Over 38.5 268 92 176 414 143 271
09/29/2019 BUF 10 - NE 16 BUF +7.5 Under 41.5 224 74 150 375 135 240
12/23/2018 NE 24 - BUF 12 BUF +13.5 Under 45 289 72 217 390 273 117
10/29/2018 BUF 6 - NE 25 NE -13 Under 44.5 387 76 311 333 46 287
12/24/2017 NE 37 - BUF 16 NE -11 Over 47 326 84 242 411 193 218
12/03/2017 BUF 3 - NE 23 NE -7.5 Under 48.5 435 191 244 268 183 85
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
01/18/2026 NE 28 - HOU 16 W -3.5 Over 41.5 241 48 193
01/11/2026 NE 16 - LAC 3 W -3.5 Under 45.5 207 87 120
01/04/2026 NE 38 - MIA 10 W -14 Over 44.5 180 63 117
12/28/2025 NYJ 10 - NE 42 W -12.5 Over 42.5 440 155 285
12/21/2025 BAL 24 - NE 28 W +2.5 Over 48.5 453 79 374
12/14/2025 NE 31 - BUF 35 L +4.5 Over 49.5 349 168 181
12/01/2025 NE 33 - NYG 15 W -7.5 Over 46.5 239 111 128
11/23/2025 CIN 20 - NE 26 L -6.5 Under 50 392 107 285
11/13/2025 NE 27 - NYJ 14 W -5.5 Under 42.5 245 140 105
11/09/2025 TB 23 - NE 28 W +2.5 Over 48 435 166 269
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
01/17/2026 DEN 33 - BUF 30 L +1.5 Over 46.5 349 70 279
01/11/2026 JAC 24 - BUF 27 W -1 Under 51.5 359 154 205
01/04/2026 BUF 35 - NYJ 8 W -13 Over 39 470 211 259
12/28/2025 BUF 12 - PHI 13 L -2.5 Under 44.5 331 120 211
12/21/2025 CLE 20 - BUF 23 L -10 Over 41 294 160 134
12/14/2025 NE 31 - BUF 35 W -4.5 Over 49.5 385 246 139
12/07/2025 BUF 39 - CIN 34 L -6 Over 32.5 416 183 233
11/30/2025 PIT 7 - BUF 26 W -3.5 Under 47.5 166 58 108
11/20/2025 HOU 23 - BUF 19 L -5 Under 44.5 261 108 153
11/16/2025 BUF 44 - TB 32 W -6 Over 45.5 414 97 317

Matchup Edge - Scoring Stats

avg rank edge in rank avg
28.82 2 Points Per Game 4 28.29
18.82 4 Points Allowed Per Game 12 21.47
7.18 1 1st Quarter Scoring Per Game 10 5
4.35 12 1st Quarter Scoring Allowed Per Game 16 4.82
10.24 2 2nd Quarter Scoring Per Game 11 7.35
5.12 5 2nd Quarter Scoring Allowed Per Game 19 8.18
6.12 7 3rd Quarter Scording Per Game 3 7.06
3.35 6 3rd Quarter Scoring Allowed Per Game 1 2.53
5.29 22 4th Quarter Scoring Per Game 1 8.88
6 12 4th Quarter Scoring Allowed Per Game 11 5.94
57.1 13 Red Zone Efficiency 3 66.2
379.35 3 Total Yards Per Game 4 376.29
12.85 3 Total Yards Per Play 2 12.92
4.44 12 Rushing Yards Per Play 2 4.96
29.53 19 Passing Attempts Per Game 21 29.12
11.8 2 Passing Yards Per Completion 12 10.71
1.82 5 Passing Tds Per Game 6 1.71
21.24 12 Completions Per Game 15 20.24
71.9 1 Completion % 2 69.5
112.96 1 Qb Rating 4 104.62
2.82 7 Defense Sacks Per Game 11 2.35
0.47 13 Defense Interceptions Per Game 11 0.59
0.82 4 Opponent Fumbles Per Game 8 1.06
0.47 6 Opponent Fumbles Lost Per Game 5 0.53
5.82 5 Penalties Per Game 7 5.94
50.24 17 Penalty Yards Per Game 16 49.88
16 5 Takeaway / Giveaway Differential 8 19
7.12 2 Yards Per Punt Return 18 3.96
25.46 19 Yards Per Kickoff Return 4 27.91

Odds Analysis

Team Rankings

offence
New England Patriots NE
Season stats rank
Total Yards 379.4 3
Passing Yards 250.47 4
Rushing Yards 128.88 6
Points Scored 28.82 2
Field Goal % 0.84 19
Buffalo Bills BUF
Season stats rank
Total Yards 376.3 4
Passing Yards 216.65 15
Rushing Yards 159.65 1
Points Scored 28.29 4
Field Goal % 0.9 8
defence
New England Patriots NE
Season stats rank
Total Yards 379.4 3
Passing Yards 250.47 4
Rushing Yards 128.88 6
Points Scored 28.82 2
Field Goal % 0.84 19
Buffalo Bills BUF
Season stats rank
Total Yards 376.3 4
Passing Yards 216.65 15
Rushing Yards 159.65 1
Points Scored 28.29 4
Field Goal % 0.9 8

Injuries

New England Patriots NE
Buffalo Bills BUF

AFC East Standings

Line Up - Last Game

Pitchers
POS Player
Hitters
POS Player
Pitchers
POS Player
Hitters
POS Player