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Patriots vs. Bills Prediction, Odds & Stats October 04, 2026

Game Scheduled
AFC East
Oct 4th, 1:00 PM EDT
New England
Patriots
L W L L W
Buffalo
Bills
W W W W W
VS
New England Patriots
Buffalo Bills
Scoreboard Spread Moneyline O/U
New England Patriots 1-2 - - -
Buffalo Bills 3-0 - - -
Loading odds...

Latest Encounters

Date Result Competition Stats Recap
09/27/26
L.A. Chargers Chargers LAC ( 0-3 )
Buffalo Bills BUF ( 3-0 )
16   -   24
 AFC West
09/27/26
New England Patriots NE ( 1-2 )
Jacksonville Jaguars JAC ( 2-1 )
6   -   35
 AFC East
09/20/26
Pittsburgh Steelers PIT ( 2-1 )
New England Patriots NE ( 1-2 )
3   -   20
 AFC North

Line History

Matchup Details

New England Patriots NE
Buffalo Bills BUF
Stat
0 Games Won 0
0 Games Lost 0
1-2 Last 10 3-0
0-0 W L Streak 0-0
0-0 Against The Spread 0-0
0 Money 0
0-0 Home 0-0
0-0 Away 0-0
0-0 Total 0-0

Recent Meetings

date home-away ats o/u BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards NE:Total Net Yards NE:Net Rushing Yards NE:Passing Yards
12/14/2025 NE 31 - BUF 35 BUF -4.5 Over 49.5 349 168 181 385 246 139
10/05/2025 BUF 20 - NE 23 NE +8.5 Under 49.5 338 71 267 363 118 245
01/05/2025 NE 23 - BUF 16 NE +3 Under 40 259 130 129 309 77 232
12/22/2024 BUF 24 - NE 21 NE +14 Under 46.5 379 126 253 324 172 152
12/31/2023 BUF 27 - NE 21 NE +12 Over 40 294 103 191 281 127 154
10/22/2023 NE 29 - BUF 25 NE +8.5 Over 41 339 81 258 364 96 268
01/08/2023 BUF 35 - NE 23 BUF -8 Over 44 341 107 234 327 90 237
12/01/2022 NE 10 - BUF 24 BUF -5.5 Under 44 355 132 223 242 60 182
01/15/2022 BUF 47 - NE 17 BUF -4.5 Over 43.5 305 89 216 482 174 308
12/26/2021 NE 21 - BUF 33 BUF +1 Over 44.5 428 114 314 288 149 139
12/06/2021 BUF 10 - NE 14 NE +3 Under 41 241 222 19 230 99 131
12/28/2020 NE 9 - BUF 38 BUF -6.5 Under 47.5 474 130 344 201 145 56
11/01/2020 BUF 24 - NE 21 NE +4 Over 41 349 188 161 339 190 149
12/21/2019 NE 24 - BUF 17 NE -6.5 Over 38.5 268 92 176 414 143 271
09/29/2019 BUF 10 - NE 16 BUF +7.5 Under 41.5 224 74 150 375 135 240
12/23/2018 NE 24 - BUF 12 BUF +13.5 Under 45 289 72 217 390 273 117
10/29/2018 BUF 6 - NE 25 NE -13 Under 44.5 387 76 311 333 46 287
12/24/2017 NE 37 - BUF 16 NE -11 Over 47 326 84 242 411 193 218
12/03/2017 BUF 3 - NE 23 NE -7.5 Under 48.5 435 191 244 268 183 85
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
09/27/2026 JAC 35 - NE 6 L +2.5 Under 45 317 83 234
09/20/2026 NE 20 - PIT 3 W -5 Under 43 235 91 144
09/09/2026 SEA 13 - NE 10 L +3.5 Under 44.5 277 109 168
08/27/2026 CLE 37 - NE 13 L -1 Over 35 276 114 162
08/22/2026 NE 24 - PHI 21 W -1 Over 37 301 90 211
08/13/2026 NE 13 - IND 13 W +1 Under 38 355 133 222
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
09/27/2026 BUF 24 - LAC 16 W -7 Under 50.5 350 176 174
09/17/2026 BUF 41 - DET 31 W -3 Over 52.5 446 203 243
09/13/2026 HOU 31 - BUF 36 W -1.5 Over 44.5 381 124 257
08/27/2026 BUF 28 - PIT 27 L -1 Over 35 266 89 177
08/22/2026 CLE 7 - BUF 31 W +1 Under 39.5 194 84 110
08/15/2026 BUF 29 - CAR 14 W +1 Over 38 420 151 269

Odds Analysis

Team Rankings

New England Patriots NE
Season stats rank
Total Yards 278.3 5
Passing Yards 170 3
Rushing Yards 108.33 17
Points Scored 17 6
Field Goal % 0.6 3
Buffalo Bills BUF
Season stats rank
Total Yards 361.3 24
Passing Yards 254.33 27
Rushing Yards 107 16
Points Scored 26 21
Field Goal % 0.83 13
New England Patriots NE
Season stats rank
Total Yards 307 22
Passing Yards 197.67 20
Rushing Yards 109.33 14
Points Scored 12 31
Field Goal % 0.71 27
Buffalo Bills BUF
Season stats rank
Total Yards 401.7 4
Passing Yards 246.67 9
Rushing Yards 155 4
Points Scored 33.67 1
Field Goal % 1 1

Injuries

New England Patriots NE
Buffalo Bills BUF

New England vs. Buffalo Betting News

New England Patriots NE

No posts found.
Buffalo Bills BUF

No posts found.

AFC East Standings

Line Up - Last Game

New England Patriots
Pitchers
POS Player
Hitters
POS Player
Buffalo Bills
Pitchers
POS Player
Hitters
POS Player