Betting Action
Recent Meetings
| date | home-away | ats | o/u | BUF:Total Net Yards | BUF:Net Rushing Yards | BUF:Passing Yards | SF:Total Net Yards | SF:Net Rushing Yards | SF:Passing Yards |
|---|---|---|---|---|---|---|---|---|---|
| 12/01/2024 | BUF 35 - SF 10 | BUF -6.5 | Under 46 | 372 | 220 | 152 | 239 | 153 | 86 |
| 12/07/2020 | SF 24 - BUF 34 | BUF -3 | Over 48 | 449 | 81 | 368 | 402 | 86 | 316 |
| date | score | ats | o/u | Total Net Yards | Net Rushing Yards | Passing Yards |
|---|---|---|---|---|---|---|
| 01/05/2025 | ARI 47 - SF 24 | L +4.5 | Over 43.5 | 436 | 138 | 298 |
| 12/30/2024 | SF 34 - DET 40 | L +3.5 | Over 51.5 | 439 | 152 | 287 |
| 12/22/2024 | MIA 29 - SF 17 | L +2.5 | Under 46 | 374 | 81 | 293 |
| 12/12/2024 | SF 6 - LAR 12 | L -1.5 | Under 48.5 | 302 | 142 | 160 |
| 12/08/2024 | SF 38 - CHI 13 | W -3.5 | Over 43.5 | 162 | 68 | 94 |
| 12/01/2024 | BUF 35 - SF 10 | L +6.5 | Under 46 | 239 | 153 | 86 |
| 11/24/2024 | GB 38 - SF 10 | L +6 | Over 45 | 241 | 44 | 197 |
| 11/17/2024 | SF 17 - SEA 20 | L -6 | Under 48.5 | 289 | 94 | 195 |
| 11/10/2024 | TB 20 - SF 23 | L -6.5 | Under 49.5 | 413 | 75 | 338 |
| 10/27/2024 | SF 30 - DAL 24 | W -5.5 | Over 47.5 | 292 | 56 | 236 |
| date | score | ats | o/u | Total Net Yards | Net Rushing Yards | Passing Yards |
|---|---|---|---|---|---|---|
| 01/26/2025 | KC 32 - BUF 29 | L +1.5 | Over 49 | 368 | 135 | 233 |
| 01/19/2025 | BUF 27 - BAL 25 | W +1 | Over 51.5 | 273 | 147 | 126 |
| 01/12/2025 | BUF 31 - DEN 7 | W -7.5 | Under 47 | 471 | 210 | 261 |
| 01/05/2025 | NE 23 - BUF 16 | L -3 | Under 40 | 309 | 77 | 232 |
| 12/29/2024 | BUF 40 - NYJ 14 | W -10.5 | Over 44 | 348 | 97 | 251 |
| 12/22/2024 | BUF 24 - NE 21 | L -14 | Under 46.5 | 324 | 172 | 152 |
| 12/15/2024 | DET 42 - BUF 48 | W +2.5 | Over 56 | 521 | 48 | 473 |
| 12/08/2024 | LAR 44 - BUF 42 | L -4.5 | Over 51 | 457 | 137 | 320 |
| 12/01/2024 | BUF 35 - SF 10 | W -6.5 | Under 46 | 372 | 220 | 152 |
| 11/17/2024 | BUF 30 - KC 21 | W -2.5 | Over 47 | 366 | 104 | 262 |
Odds Analysis
Team Rankings
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Injuries
| player (position) | status | ats*current | o/u* | notes | |
|---|---|---|---|---|---|
| Ji'ayir Brown (S) | Questionable | Ankle - 02 / 01 / 25 | 0-0 | 0-0 | Details |
| Isaac Yiadom (CB) | Questionable | Pelvis - 02 / 01 / 25 | 0-0 | 0-0 | Details |
| Colton McKivitz (OL) | Questionable | Knee - 02 / 01 / 25 | 0-0 | 0-0 | Details |
| Deommodore Lenoir (DB) | Out | Shoulder - 02 / 01 / 25 | 0-0 | 0-0 | Details |
| Ricky Pearsall (WR) | Questionable | Illness - 02 / 01 / 25 | 0-0 | 0-0 | Details |
| Deebo Samuel Sr. (WR) | Out | Ribs - 02 / 01 / 25 | 0-0 | 0-0 | Details |
| Demetrius Flannigan-Fowles (LB) | Out indefinitely | Calf - 31 / 12 / 24 | 0-0 | 0-0 | Details |
| Brock Purdy (QB) | Out | Elbow - 31 / 12 / 24 | 0-0 | 0-0 | Details |
| Leonard Floyd (DL) | Questionable | Shoulder - 31 / 12 / 24 | 0-0 | 0-0 | Details |
| Charvarius Ward (CB) | Questionable | Personal - 29 / 12 / 24 | 0-0 | 0-0 | Details |
| player (position) | status | ats*current | o/u* | notes | |
|---|---|---|---|---|---|
| Matt Milano (LB) | Questionable | Hamstring - 22 / 01 / 25 | 0-0 | 0-0 | Details |
| Baylon Spector (LB) | Out indefinitely | Calf - 22 / 01 / 25 | 0-0 | 0-0 | Details |
| Taylor Rapp (S) | Out | Hip - 20 / 01 / 25 | 0-0 | 0-0 | Details |
| Christian Benford (CB) | Questionable | Concussion - 20 / 01 / 25 | 0-0 | 0-0 | Details |
| Alec Anderson (OT) | Questionable | Calf - 15 / 01 / 25 | 0-0 | 0-0 | Details |
| Ray Davis (RB) | Questionable | Concussion - 14 / 01 / 25 | 0-0 | 0-0 | Details |
| Ray Davis (RB) | Questionable | Head - 12 / 01 / 25 | 0-0 | 0-0 | Details |
| Ja'Marcus Ingram (CB) | Questionable | Personal - 08 / 01 / 25 | 0-0 | 0-0 | Details |
| Brandon Codrington (CB) | Questionable | Hamstring - 08 / 01 / 25 | 0-0 | 0-0 | Details |
| Amari Cooper (WR) | Questionable | Personal - 07 / 01 / 25 | 0-0 | 0-0 | Details |
San Francisco Vs Buffalo Betting Trends
49ers are 4-11 ATS in their last 15 games as a favorite of 3.5-10.0.
Over is 5-2 in 49ers last 7 games as an underdog of 10.5 or greater.
Under is 4-0 in 49ers last 4 games following a bye week.
49ers are 2-7 ATS in their last 9 games as a road favorite of 3.5-10.0.
49ers are 4-10 ATS in their last 14 games as a favorite.
Bills are 5-2 ATS in their last 7 games as a favorite of 3.5-10.0.
Under is 4-1 in Bills last 5 games as an underdog of 10.5 or greater.
Under is 4-1 in Bills last 5 games following a bye week.
Over is 5-1 in Bills last 6 games overall.
Bills are 6-1 ATS in their last 7 games as a favorite.
National Football Conference Standings
Line Up - Last Game
Pitchers
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