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Wyoming Cowboys vs. Colorado Buffaloes Odds, Stats - September 20, 2025

Final Score
Sep 20th, 10:15 PM EDT
Wyoming
Cowboys
Colorado
Buffaloes
20
37
Wyoming Cowboys
Colorado Buffaloes
Scoreboard 1 2 3 4 Odds
Wyoming Cowboys 4-8 0 3 10 7 +45.5
Colorado Buffaloes 3-9 0 21 7 9 -12.5

Latest Encounters

Date Result Competition Stats Recap
11/29/25
Wyoming Cowboys WYO ( 4-8 )
Hawaii Rainbow Warriors HAW ( 8-4 )
7   -   27
11/29/25
Colorado Buffaloes COLO ( 3-9 )
Kansas State Wildcats KSU ( 6-6 )
14   -   24
11/22/25
Arizona State Sun Devils ASU ( 8-4 )
Colorado Buffaloes COLO ( 3-9 )
42   -   17
11/22/25
Nevada Wolf Pack NEV ( 3-9 )
Wyoming Cowboys WYO ( 4-8 )
13   -   7
11/15/25
Wyoming Cowboys WYO ( 4-8 )
Fresno State Bulldogs FRES ( 8-4 )
3   -   24
11/08/25
Colorado Buffaloes COLO ( 3-9 )
West Virginia Mountaineers WVU ( 4-8 )
22   -   29
11/01/25
Wyoming Cowboys WYO ( 4-8 )
San Diego State Aztecs SDSU ( 9-3 )
7   -   24
11/01/25
Arizona Wildcats ARIZ ( 9-3 )
Colorado Buffaloes COLO ( 3-9 )
52   -   17
10/25/25
Colorado Buffaloes COLO ( 3-9 )
Utah Utes UTAH ( 10-2 )
7   -   53
10/25/25
Colorado State Rams CSU ( 2-10 )
Wyoming Cowboys WYO ( 4-8 )
0   -   28
10/18/25
Wyoming Cowboys WYO ( 4-8 )
Air Force Falcons AFA ( 4-8 )
21   -   24
10/11/25
Iowa State Cyclones ISU ( 8-4 )
Colorado Buffaloes COLO ( 3-9 )
17   -   24

Matchup Odds

Team Spread Moneyline Over / Under
Wyoming Cowboys WYO
+12.5 0 0 U+45.50
Colorado Buffaloes COLO
-12.5 0 0 O+45.50

Line History

time fav line total
Opening 14 Sep 7:33pm WYO O +44.5 -105
Closing 21 Sep 5:34am WYO O +51.5 -102

Line History

Team Leaders

Wyoming Cowboys WYO
Colorado Buffaloes COLO
Omarion Miller
Wide Receiver Wyoming
8 Touchdowns 4
Chris Durr Jr.
Wide Receiver Colorado
Samuel Harris
Running Back Colorado
558 Rushing 384
Micah Welch
Running Back Wyoming
Kaden Anderson
Quarterback Colorado
1971 Passing 1414
Kaidon Salter
Quarterback Wyoming
Omarion Miller
Wide Receiver Wyoming
45 Receiving 45
Chris Durr Jr.
Wide Receiver Colorado
Ben Florentine
Nose Tackle Colorado
4 Sacks 2.5
Keaten Wade
Defensive End Wyoming
John Slaughter
Safety Wyoming
2 Interceptions 2
Desman Hearns
Safety Colorado

Matchup Details

team win loss last 10 w/l streak ats money home away total
Wyoming Cowboys Wyoming Cowboys
2 1 2-8 4L 2-1 0 0-0 0-0 0-3
Colorado Buffaloes Colorado Buffaloes
1 2 2-8 5L 1-2 0 0-0 0-0 1-2

Recent Meetings

date home-away ats o/u COLO:Total Net Yards COLO:Net Rushing Yards COLO:Passing Yards WYO:Total Net Yards WYO:Net Rushing Yards WYO:Passing Yards
09/20/2025 COLO 37 - WYO 20 COLO -13.5 Over 45.5 497 193 304 347 165 182
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
11/29/2025 HAW 27 - WYO 7 L +10.5 Under 44.5 256 54 202
11/22/2025 WYO 7 - NEV 13 L -7.5 Under 39.5 271 213 58
11/15/2025 FRES 24 - WYO 3 L +3 Under 40.5 184 107 77
11/01/2025 SDSU 24 - WYO 7 L +10.5 Under 41.5 185 89 96
10/25/2025 WYO 28 - CSU 0 W -4.5 Under 46.5 305 94 211
10/18/2025 AFA 24 - WYO 21 W +5.5 Under 57.5 409 198 211
10/11/2025 WYO 35 - SJSU 28 W +1.5 Over 49.5 383 43 340
10/04/2025 WYO 17 - UNLV 31 L +4.5 Under 50.5 255 153 102
09/20/2025 COLO 37 - WYO 20 L +13.5 Over 45.5 347 165 182
09/13/2025 WYO 6 - UTAH 31 L +23.5 Under 46.5 541 311 230
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
11/29/2025 KSU 24 - COLO 14 W +17 Under 49.5 321 206 115
11/22/2025 COLO 17 - ASU 42 L +7.5 Over 47.5 300 135 165
11/08/2025 WVU 29 - COLO 22 L +5.5 Under 52.5 369 167 202
11/01/2025 COLO 17 - ARIZ 52 L +4.5 Over 52.5 299 129 170
10/25/2025 UTAH 53 - COLO 7 L +14 Over 50.5 587 422 165
10/11/2025 COLO 24 - ISU 17 W +4.5 Under 51.5 395 140 255
10/04/2025 TCU 35 - COLO 21 L +13.5 Under 57.5 369 94 275
09/27/2025 COLO 21 - BYU 24 W +6.5 Under 48.5 291 172 119
09/20/2025 COLO 37 - WYO 20 W -13.5 Over 45.5 497 193 304
09/12/2025 HOU 36 - COLO 20 L +4.5 Over 45.5 431 209 222

Matchup Edge - Scoring Stats

Wyoming Cowboys WYO
Colorado Buffaloes COLO
avg rank edge in rank avg
16 147 Points Per Game 122 20.92
20.5 33 Points Allowed Per Game 120 30.5
4 75 1st Quarter Scoring Per Game 80 3.5
4.83 40 1st Quarter Scoring Allowed Per Game 51 5.5
3.08 111 2nd Quarter Scoring Per Game 75 7.08
7.08 48 2nd Quarter Scoring Allowed Per Game 92 10.58
3.75 82 3rd Quarter Scording Per Game 65 5.17
3.25 17 3rd Quarter Scoring Allowed Per Game 63 6.33
5.17 80 4th Quarter Scoring Per Game 80 5.17
5.33 35 4th Quarter Scoring Allowed Per Game 78 8.08
68.0 92 Red Zone Efficiency 37 86.1
314.67 121 Total Yards Per Game 111 328.42
9.81 121 Total Yards Per Play 101 11.04
4.05 72 Rushing Yards Per Play 100 3.5
32.08 41 Passing Attempts Per Game 60 29.75
10.21 120 Passing Yards Per Completion 70 11.59
1.08 29 Passing Tds Per Game 23 1.42
17.92 62 Completions Per Game 68 17.5
55.8 103 Completion % 85 58.8
108.67 150 Qb Rating 100 125.65
1.58 31 Defense Sacks Per Game 7 3.25
1 7 Defense Interceptions Per Game 8 0.92
0.5 11 Opponent Fumbles Lost Per Game 11 0.5
6.58 70 Penalties Per Game 56 5.67
56.25 122 Penalty Yards Per Game 98 49.92
18 16 Takeaway / Giveaway Differential 15 17
3.61 49 Yards Per Punt Return 113 1.22
16.92 129 Yards Per Kickoff Return 35 22.87

Odds Analysis

Team Rankings

offence
Wyoming Cowboys WYO
Season stats rank
Total Yards 314.7 122
Passing Yards 183 110
Rushing Yards 131.67 99
Points Scored 16 603
Field Goal % 0.5 186
Colorado Buffaloes COLO
Season stats rank
Total Yards 328.4 112
Passing Yards 202.83 93
Rushing Yards 125.58 104
Points Scored 20.92 509
Field Goal % 0.75 131
defence
Wyoming Cowboys WYO
Season stats rank
Total Yards 314.7 122
Passing Yards 183 110
Rushing Yards 131.67 99
Points Scored 16 603
Field Goal % 0.5 186
Colorado Buffaloes COLO
Season stats rank
Total Yards 328.4 112
Passing Yards 202.83 93
Rushing Yards 125.58 104
Points Scored 20.92 509
Field Goal % 0.75 131

Injuries

Wyoming Cowboys WYO
Colorado Buffaloes COLO

Betting News + Tweets

Wyoming Cowboys WYO

No posts found.
Colorado Buffaloes COLO

No posts found.

Wyoming Vs Colorado Betting Trends

Wyoming Cowboys WYO

Cowboys are 6-0 ATS in their last 6 games following a straight up loss.

Cowboys are 12-3-1 ATS in their last 16 games as a favorite of 3.5-10.0.

Cowboys are 13-4-1 ATS in their last 18 games following a ATS loss.

Under is 4-0 in Cowboys last 4 games as an underdog of 10.5 or greater.

Under is 6-0 in Cowboys last 6 games overall.

Colorado Buffaloes COLO

Buffaloes are 9-1-1 ATS in their last 11 games following a straight up loss.

Buffaloes are 9-0 ATS in their last 9 games as a favorite of 3.5-10.0.

Buffaloes are 6-1 ATS in their last 7 games following a ATS loss.

Under is 5-1 in Buffaloes last 6 games overall.

Buffaloes are 7-2 ATS in their last 9 games as a favorite.

Mountain West Standings

Big 12 Standings

Line Up - Last Game

Wyoming Cowboys
Pitchers
POS Player
Hitters
POS Player
Colorado Buffaloes
Pitchers
POS Player
Hitters
POS Player
  • WYO
  • +12.5 -12.5
  • COLO
NCAAF Odds