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Virginia Cavaliers vs. Louisville Cardinals Odds, Stats - October 04, 2025

Final Score
Oct 4th, 3:30 PM EDT
Virginia
Cavaliers
Louisville
Cardinals
30
27
Virginia Cavaliers
Louisville Cardinals
Scoreboard Final(OT) 1 2 3 4 O Odds
Virginia Cavaliers 10-3 30 7 7 10 0 6 +60.5
Louisville Cardinals 8-4 27 7 7 0 10 3 -6.5

Latest Encounters

Date Result Competition Stats Recap
12/27/25
Virginia Cavaliers UVA ( 10-3 )
Missouri Tigers MIZZ ( 8-4 )
13   -   7
12/23/25
Toledo Rockets TOL ( 8-4 )
Louisville Cardinals LOU ( 8-4 )
22   -   27
12/06/25
Duke Blue Devils DUKE ( 8-5 )
Virginia Cavaliers UVA ( 10-3 )
27   -   20
11/29/25
Virginia Tech Hokies VT ( 3-9 )
Virginia Cavaliers UVA ( 10-3 )
7   -   27
11/29/25
Kentucky Wildcats UK ( 5-7 )
Louisville Cardinals LOU ( 8-4 )
0   -   41
11/22/25
Louisville Cardinals LOU ( 8-4 )
Southern Methodist Mustangs SMU ( 8-4 )
6   -   38
11/15/25
Virginia Cavaliers UVA ( 10-3 )
Duke Blue Devils DUKE ( 8-5 )
34   -   17
11/14/25
Clemson Tigers CLEM ( 7-5 )
Louisville Cardinals LOU ( 8-4 )
20   -   19
11/08/25
Wake Forest Demon Deacons WAKE ( 8-4 )
Virginia Cavaliers UVA ( 10-3 )
16   -   9
11/08/25
California Golden Bears CAL ( 7-5 )
Louisville Cardinals LOU ( 8-4 )
29   -   26
11/01/25
Virginia Cavaliers UVA ( 10-3 )
California Golden Bears CAL ( 7-5 )
31   -   21
11/01/25
Louisville Cardinals LOU ( 8-4 )
Virginia Tech Hokies VT ( 3-9 )
28   -   16

Matchup Odds

Team Spread Moneyline Over / Under
Virginia Cavaliers UVA
+6.5 0 0 U+60.50
Louisville Cardinals LOU
-6.5 0 0 O+60.50

Line History

time fav line total
Opening 28 Sep 8:38pm UVA O +61.5 -110
Closing 4 Oct 10:37pm UVA U +52.5 -185

Line History

Team Leaders

Virginia Cavaliers UVA
Louisville Cardinals LOU
J'Mari Taylor
Running Back Louisville
16 Touchdowns 6
Chris Bell
Wide Receiver Virginia
J'Mari Taylor
Running Back Louisville
1062 Rushing 782
Isaac Brown
Running Back Virginia
Chandler Morris
Quarterback Louisville
2802 Passing 2526
Miller Moss
Quarterback Virginia
Chris Bell
Wide Receiver Virginia
72 Receiving 59
Trell Harris
Wide Receiver Louisville
Daniel Rickert
Defensive Lineman Louisville
7 Sacks 6.5
Clev Lubin
Defensive Lineman Virginia
Antonio Watts
Linebacker Virginia
3 Interceptions 3
Ja'Son Prevard
Defensive Back Louisville
Virginia Cavaliers UVA
Louisville Cardinals LOU
Isaac Brown
Running Back Virginia
2 Touchdowns 1
Harrison Waylee
Running Back Louisville
Keyjuan Brown
Running Back Virginia
112 Rushing 68
Harrison Waylee
Running Back Louisville
Chandler Morris
Quarterback Louisville
198 Passing 153
Miller Moss
Quarterback Virginia
Caullin Lacy
Wide Receiver Virginia
6 Receiving 5
Sage Ennis
Tight End Louisville
Clev Lubin
Defensive Lineman Virginia
1.5 Sacks 0
Will Bettridge
PK Louisville
Emmanuel Karnley
Cornerback Louisville
1 Interceptions 0
Isaac Brown
Running Back Virginia

Matchup Details

team win loss last 10 w/l streak ats money home away total
Virginia Cavaliers Virginia Cavaliers
4 1 8-2 1L 4-1 0 0-0 0-0 4-1
Louisville Cardinals Louisville Cardinals
4 0 6-4 1W 1-3 0 0-0 0-0 3-1

Recent Meetings

date home-away ats o/u LOU:Total Net Yards LOU:Net Rushing Yards LOU:Passing Yards UVA:Total Net Yards UVA:Net Rushing Yards UVA:Passing Yards
10/04/2025 LOU 27 - UVA 30 UVA +6.5 Under 61.5 383 54 329 237 88 149
10/12/2024 UVA 20 - LOU 24 UVA +7 Under 56 408 177 231 449 148 301
11/09/2023 LOU 31 - UVA 24 UVA +20.5 Over 51 434 120 314 423 180 243
10/08/2022 UVA 17 - LOU 34 LOU -4.5 Over 47.5 475 200 275 319 6 313
10/09/2021 LOU 33 - UVA 34 UVA +2.5 Over 65.5 522 35 487 503 233 270
11/14/2020 UVA 31 - LOU 17 UVA -2.5 Under 64.5 478 317 161 368 165 203
10/26/2019 LOU 28 - UVA 21 LOU +3.5 Under 51 311 78 233 360 227 133
09/22/2018 UVA 27 - LOU 3 UVA -3.5 Under 56.5 214 66 148 401 204 197
11/11/2017 LOU 38 - UVA 21 LOU -13.5 Under 66 277 63 214 493 298 195
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
12/27/2025 MIZZ 7 - UVA 13 W +7 Under 50.5 308 110 198
12/06/2025 UVA 20 - DUKE 27 L -2.5 Under 58.5 333 137 196
11/29/2025 UVA 27 - VT 7 W -10.5 Under 52.5 197 119 78
11/15/2025 DUKE 17 - UVA 34 W +5.5 Under 60.5 540 224 316
11/08/2025 UVA 9 - WAKE 16 L -6.5 Under 48.5 203 139 64
11/01/2025 CAL 21 - UVA 31 W -6 Under 52.5 456 194 262
10/25/2025 UNC 16 - UVA 17 L -9.5 Under 52.5 259 59 200
10/18/2025 UVA 22 - WSU 20 L -15.5 Under 55.5 326 143 183
10/04/2025 LOU 27 - UVA 30 W +6.5 Under 61.5 237 88 149
09/26/2025 UVA 46 - FSU 38 W +7 Over 60.5 516 258 258
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
12/23/2025 LOU 27 - TOL 22 L -9.5 Over 44.5 333 180 153
11/29/2025 LOU 41 - UK 0 W -3.5 Under 47.5 440 258 182
11/22/2025 SMU 38 - LOU 6 L +3.5 Under 53.5 485 178 307
11/14/2025 LOU 19 - CLEM 20 W +5.5 Under 60.5 385 171 214
11/08/2025 LOU 26 - CAL 29 L -18.5 Over 49.5 351 148 203
11/01/2025 VT 16 - LOU 28 W -10.5 Under 54.5 240 164 76
10/25/2025 LOU 38 - BC 24 L -25.5 Over 54.5 506 319 187
10/17/2025 MIA 21 - LOU 24 W +10.5 Under 49.5 334 63 271
10/04/2025 LOU 27 - UVA 30 L -6.5 Under 61.5 383 54 329
09/27/2025 PITT 27 - LOU 34 W -3.5 Over 54.5 339 80 259

Matchup Edge - Scoring Stats

Virginia Cavaliers UVA
Louisville Cardinals LOU
avg rank edge in rank avg
32.15 39 Points Per Game 52 30.17
20.54 34 Points Allowed Per Game 37 21.08
8.23 23 1st Quarter Scoring Per Game 35 6.92
2.69 10 1st Quarter Scoring Allowed Per Game 55 5.83
9.85 37 2nd Quarter Scoring Per Game 53 8.83
7.38 51 2nd Quarter Scoring Allowed Per Game 30 6
7.54 31 3rd Quarter Scording Per Game 49 6.25
4.92 41 3rd Quarter Scoring Allowed Per Game 17 3.25
4.69 87 4th Quarter Scoring Per Game 45 7.67
4.08 18 4th Quarter Scoring Allowed Per Game 28 5
83.6 51 Red Zone Efficiency 48 84.2
426.31 28 Total Yards Per Game 70 388.83
12.21 73 Total Yards Per Play 84 11.84
4.72 35 Rushing Yards Per Play 22 5.07
34.92 21 Passing Attempts Per Game 33 32.83
10.86 96 Passing Yards Per Completion 98 10.77
1.38 24 Passing Tds Per Game 25 1.33
22.31 22 Completions Per Game 32 21
63.9 46 Completion % 45 64.0
130.84 83 Qb Rating 86 130.68
1.31 36 Defense Sacks Per Game 27 1.75
0.77 10 Defense Interceptions Per Game 11 0.75
0.23 17 Opponent Fumbles Lost Per Game 9 0.58
5.38 51 Penalties Per Game 76 7
45.23 83 Penalty Yards Per Game 154 64.5
13 11 Takeaway / Giveaway Differential 14 16
6.26 17 Yards Per Punt Return 7 8.92
30.6 5 Yards Per Kickoff Return 39 22.69

Odds Analysis

Team Rankings

offence
Virginia Cavaliers UVA
Season stats rank
Total Yards 426.3 28
Passing Yards 242.31 56
Rushing Yards 184 40
Points Scored 32.15 162
Field Goal % 0.81 89
Louisville Cardinals LOU
Season stats rank
Total Yards 388.8 70
Passing Yards 226.25 67
Rushing Yards 162.58 64
Points Scored 30.17 222
Field Goal % 0.82 80
defence
Virginia Cavaliers UVA
Season stats rank
Total Yards 426.3 28
Passing Yards 242.31 56
Rushing Yards 184 40
Points Scored 32.15 162
Field Goal % 0.81 89
Louisville Cardinals LOU
Season stats rank
Total Yards 388.8 70
Passing Yards 226.25 67
Rushing Yards 162.58 64
Points Scored 30.17 222
Field Goal % 0.82 80

Injuries

Virginia Cavaliers UVA
Louisville Cardinals LOU

Betting News + Tweets

Virginia Cavaliers UVA

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Louisville Cardinals LOU

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Virginia Vs Louisville Betting Trends

Virginia Cavaliers UVA

Cavaliers are 16-6-2 ATS in their last 24 games after scoring more than 40 points in their previous game.

Over is 11-3-1 in Cavaliers last 15 games as an underdog of 10.5 or greater.

Cavaliers are 15-7-1 ATS in their last 23 conference games.

Over is 4-0 in Cavaliers last 4 games overall.

Cavaliers are 5-1 ATS in their last 6 games as a favorite.

Louisville Cardinals LOU

Under is 4-0 in Cardinals last 4 games as an underdog of 10.5 or greater.

Over is 5-1 in Cardinals last 6 games overall.

Cardinals are 3-7 ATS in their last 10 games as a favorite.

Cardinals are 1-5 ATS in their last 6 home games.

Cardinals are 10-21 ATS in their last 31 games as a home underdog.

Line Up - Last Game

Virginia Cavaliers
Pitchers
POS Player
Hitters
POS Player
Louisville Cardinals
Pitchers
POS Player
Hitters
POS Player
  • UVA
  • +6.5 -6.5
  • LOU
NCAAF Odds