Clemson Tigers vs. Louisville Cardinals Odds, Stats - November 14, 2025

Final Score
Clemson
Tigers
Louisville
Cardinals
20
19
Clemson Tigers
Louisville Cardinals
Scoreboard 1 2 3 4 Odds
Clemson Tigers 7-5 3 7 3 7 +60.5
Louisville Cardinals 8-4 3 6 10 0 +6.5

Latest Encounters

Date Result Competition Stats Recap
12/27/25
Penn State Nittany Lions PSU ( 6-6 )
Clemson Tigers CLEM ( 7-5 )
22   -   10
12/23/25
Toledo Rockets TOL ( 8-4 )
Louisville Cardinals LOU ( 8-4 )
22   -   27
11/29/25
Clemson Tigers CLEM ( 7-5 )
South Carolina Gamecocks SOCAR ( 4-8 )
28   -   14
11/29/25
Kentucky Wildcats UK ( 5-7 )
Louisville Cardinals LOU ( 8-4 )
0   -   41
11/22/25
Furman Paladins FUR ( 6-6 )
Clemson Tigers CLEM ( 7-5 )
10   -   45
11/22/25
Louisville Cardinals LOU ( 8-4 )
Southern Methodist Mustangs SMU ( 8-4 )
6   -   38
11/08/25
Florida State Seminoles FSU ( 5-7 )
Clemson Tigers CLEM ( 7-5 )
10   -   24
11/08/25
California Golden Bears CAL ( 7-5 )
Louisville Cardinals LOU ( 8-4 )
29   -   26
11/01/25
Louisville Cardinals LOU ( 8-4 )
Virginia Tech Hokies VT ( 3-9 )
28   -   16
11/01/25
Clemson Tigers CLEM ( 7-5 )
46   -   45

Line History

time fav line total
Opening 10 Jul 2:35am CLEM O +60.5 -110
Closing 15 Nov 3:29am CLEM U +39.5 -140

Line History

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Matchup Edge - Scoring Stats

avg rank edge in rank avg
28.67 65 Points Per Game 52 30.17
20.42 32 Points Allowed Per Game 37 21.08
6.92 35 1st Quarter Scoring Per Game 35 6.92
4.75 39 1st Quarter Scoring Allowed Per Game 55 5.83
10.92 24 2nd Quarter Scoring Per Game 53 8.83
7.42 52 2nd Quarter Scoring Allowed Per Game 30 6
4.42 74 3rd Quarter Scording Per Game 49 6.25
4 26 3rd Quarter Scoring Allowed Per Game 17 3.25
6.42 61 4th Quarter Scoring Per Game 45 7.67
4.25 21 4th Quarter Scoring Allowed Per Game 28 5
80.0 67 Red Zone Efficiency 48 84.2
405.25 50 Total Yards Per Game 70 388.83
11.18 97 Total Yards Per Play 85 11.84
4.09 71 Rushing Yards Per Play 23 5.07
36.25 15 Passing Attempts Per Game 35 32.83
11.46 78 Passing Yards Per Completion 102 10.77
1.83 16 Passing Tds Per Game 25 1.33
23.92 10 Completions Per Game 32 21
66.0 32 Completion % 44 64.0
142.94 55 Qb Rating 87 130.68
1.42 33 Defense Sacks Per Game 27 1.75
0.58 15 Defense Interceptions Per Game 11 0.75
0.67 7 Opponent Fumbles Lost Per Game 9 0.58
4.67 40 Penalties Per Game 76 7
45.17 82 Penalty Yards Per Game 155 64.5
15 13 Takeaway / Giveaway Differential 14 16
2.67 74 Yards Per Punt Return 7 8.92
18.08 115 Yards Per Kickoff Return 39 22.69

Team Leaders

Clemson Tigers CLEM
Louisville Cardinals LOU
Adam Randall
Running Back Louisville
12 Touchdowns 6
Chris Bell
Wide Receiver Clemson
Isaac Brown
Running Back Clemson
782 Rushing 779
Adam Randall
Running Back Louisville
Cade Klubnik
Quarterback Louisville
2750 Passing 2526
Miller Moss
Quarterback Clemson
Chris Bell
Wide Receiver Clemson
72 Receiving 55
Antonio Williams
Wide Receiver Louisville
Clev Lubin
Defensive Lineman Clemson
6.5 Sacks 6
Will Heldt
Defensive End Louisville
Ricardo Jones
Safety Louisville
6 Interceptions 3
Antonio Watts
Linebacker Clemson
Clemson Tigers CLEM
Louisville Cardinals LOU
Isaac Brown
Running Back Clemson
2 Touchdowns 1
Adam Randall
Running Back Louisville
Keyjuan Brown
Running Back Clemson
112 Rushing 35
Adam Randall
Running Back Louisville
Cade Klubnik
Quarterback Louisville
193 Passing 153
Miller Moss
Quarterback Clemson
Caullin Lacy
Wide Receiver Clemson
6 Receiving 6
T.J. Moore
Wide Receiver Louisville
Clev Lubin
Defensive Lineman Clemson
1.5 Sacks 1
Ashton Hampton
Cornerback Louisville
Isaac Brown
Running Back Clemson
0 Interceptions 0
Jeremiah Alexander
Linebacker Louisville

Matchup Details

team win loss last 10 w/l streak ats money home away total
Clemson Tigers Clemson Tigers
4 5 6-4 4W 3-6 0 0-0 0-0 4-5
Louisville Cardinals Louisville Cardinals
7 2 6-4 1W 3-6 0 0-0 0-0 5-4

Team Rankings

offence
Clemson Tigers CLEM
Season stats rank
Total Yards 405.3 50
Passing Yards 274 21
Rushing Yards 131.25 99
Points Scored 28.67 284
Field Goal % 0.84 75
Louisville Cardinals LOU
Season stats rank
Total Yards 388.8 70
Passing Yards 226.25 67
Rushing Yards 162.58 64
Points Scored 30.17 222
Field Goal % 0.82 80
defence
Clemson Tigers CLEM
Season stats rank
Total Yards 405.3 50
Passing Yards 274 21
Rushing Yards 131.25 99
Points Scored 28.67 284
Field Goal % 0.84 75
Louisville Cardinals LOU
Season stats rank
Total Yards 388.8 70
Passing Yards 226.25 67
Rushing Yards 162.58 64
Points Scored 30.17 222
Field Goal % 0.82 80

Weather

No weather to report.

Injuries

Clemson Tigers CLEM
Louisville Cardinals LOU