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Houston Astros vs. Cleveland Guardians Odds, Stats April 22, 2026

Final Score
American League West
Apr 22nd, 1:10 PM EDT
Houston
Astros
Cleveland
Guardians
2
0
Houston Astros
Cleveland Guardians
Scoreboard 1 2 3 4 5 6 7 8 9 R ML H E
Houston Astros 67-67 2 0 0 0 0 0 0 0 - 2 +135 6 1
Cleveland Guardians 68-66 0 0 0 0 0 0 0 0 - 0 -160 5 0
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Latest Encounters

Date Result Competition Stats Recap
08/27/26
Houston Astros HOU ( 67-67 )
NY Yankees Yankees NYY ( 75-58 )
5   -   1
 American League West
08/26/26
Houston Astros HOU ( 67-67 )
NY Yankees Yankees NYY ( 75-58 )
3   -   9
 American League West
08/26/26
Cleveland Guardians CLE ( 68-66 )
LA Angels Angels LAA ( 52-82 )
4   -   3
 American League Central

Matchup Odds

Team Runline Moneyline Over / Under
Houston Astros HOU
+1.5 0 0 U+8.50
Cleveland Guardians CLE
-1.5 0 0 O+8.50

Line History

time fav spread money line total
Opening 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110
Closing 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110

Line History

Team Leaders

Houston Astros HOU
Cleveland Guardians CLE
Yordan Alvarez
Designated Hitter Cleveland
36 HR 13
Chase DeLauter
Right Outfield Houston
Chase DeLauter
Right Outfield Houston
0.3 BA 0.3
Yordan Alvarez
Designated Hitter Cleveland
Jose Ramirez
Third Base Houston
31 SB 10
Cam Smith
Right Outfield Cleveland

Matchup Details

Houston Astros HOU
Cleveland Guardians CLE
Stat
9 Wins 14
16 Losses 11
4-6 Last 10 8-2
-11.77 Units 5.17
7-6 Wins Home 8-4
2-10 Wins Away 6-7
18-7 Covers Against Ou 13-12
9-16 Run Line Wins Losses 15-10
-7.75 Runline Units 4.15

Matchup Edge - Scoring Stats

Houston Astros HOU
Cleveland Guardians CLE
avg rank edge in rank avg
4.11 24 Runs Per 9 Innings 5 6.18
0.618 27 On Base Plus Slugging 9 0.819
0.197 24 Batting Average 13 0.256
19 21 Home Runs 3 46

Odds Analysis

Team Rankings

Houston Astros HOU
Season stats rank
ERA 4.65 6
WHIP 1.37 7
KS 1099 17
CG - -
Errors 60 9
Cleveland Guardians CLE
Season stats rank
ERA 3.73 24
WHIP 1.26 20
KS 1086 20
CG - -
Errors 70 15
Houston Astros HOU
Season stats rank
Runs / G 4.57 10
BA 0.24 17
OPS 0.73 11
HR 179 3
SB 40 29
Cleveland Guardians CLE
Season stats rank
Runs / G 4.05 28
BA 0.24 27
OPS 0.69 29
HR 124 29
SB 129 6

Injuries

Houston Astros HOU
Cleveland Guardians CLE

Houston vs. Cleveland Betting News

Houston Astros HOU

No posts found.
Cleveland Guardians CLE

No posts found.

Houston Vs Cleveland Betting Trends

Houston Astros HOU

Over is 5-1 in Astros last 6 games vs. a right-handed starter.

Under is 5-1 in Astros last 6 Wednesday games.

Over is 7-0 in Astros last 7 games with the total set at 9.0-10.5.

Astros are 19-7 in their last 26 games with the total set at 11.0 or higher.

Over is 10-4 in Astros last 14 games as a favorite.

Cleveland Guardians CLE

Under is 6-1-3 in Guardians last 10 Wednesday games.

Under is 3-1-2 in Guardians last 6 games with the total set at 9.0-10.5.

Guardians are 5-2 in their last 7 games with the total set at 11.0 or higher.

Over is 4-1 in Guardians last 5 games as a favorite.

Guardians are 3-7 in their last 10 when their opponent allows 5 runs or more in their previous game.

Pitchers & Umpires

Today - Overall

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (R) - - - - - - 67-67 - - - - -
Tanner Bibee (R) - - - - - - 68-66 - - - - -

Today - Last 3

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (R) - - - - - - 67-67 - - - - -
Tanner Bibee (R) - - - - - - 68-66 - - - - -
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Jason Alexander (R) 4.53 1-1 9.33 14 8 0 2 21 19 19 4 0 1.58 21:10
Spencer Arrighetti (R) 5.18 7-5 4.6 87 50 0 17 68 47 45 12 0 1.34 69:53
Ronel Blanco (R) 4.62 0-1 7.71 20 12 0 4 22 20 20 7 0 1.46 22:20
Hunter Brown (R) 5.29 3-3 3.51 76 43 0 14 56 31 29 10 0 1.33 85:29
J.P. France (R) 2.07 0 8.1 4 5 0 0 6 6 6 1 0 1.65 8:6
Colton Gordon (L) 2.28 0 11.57 11 3 0 1 21 12 12 6 0 2.57 7:3
Cristian Javier (R) 3.34 1-4 6.47 38 19 0 8 48 29 29 8 0 1.66 20:40
Bryan King (L) 1.04 2-3 4.75 44 19 0 1 57 30 28 8 0 1.43 61:23
Lance McCullers Jr. (R) 4.89 2-3 6.86 43 22 0 8 38 32 30 7 0 1.53 32:18
Jayden Murray (R) 1.64 0 7.43 8 7 0 0 19 11 11 1 0 1.95 9:14
Ryan Weiss (R) 2.89 0-3 7.62 30 20 0 2 35 24 22 8 0 2.12 18:12
Mike Burrows (R) 5.23 4-9 5.99 75 35 0 17 112 69 63 21 0 1.55 85:60
Tatsuya Imai (R) 3.73 6-4 5.32 83 44 0 15 55 40 40 9 0 1.46 57:32
Kai-Wei Teng (R) 2.6 5-6 4.22 71 30 0 10 63 37 33 10 0 1.32 59:35
Ethan Pecko (R) 4 0 7.88 5 7 0 2 8 7 7 2 0 1.88 5:5
Amilcar Chirinos (R) 0.2 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Wilmy Sanchez (R) 2 0 0 3 0 0 0 0 0 0 0 0 0 2:1
Trey Dombroski (L) 1.05 0-1 11.57 1 0 0 0 3 3 3 2 0 1.29 1:3
Joey Mancini (R) 2 0 0 1 2 0 0 0 0 0 0 0 1 2:0
Alex Santos II (R) 0.1 0 0 0 0 0 0 1 0 0 0 0 3 0:1
Nolan DeVos (R) 2 0 0 1 0 0 0 1 0 0 0 0 0.5 4:1
Dylan Howard (R) 2 0 0 2 1 0 0 2 0 0 0 0 1.5 2:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Logan Allen (L) 2.42 0 2.92 13 4 0 1 14 7 4 2 0 1.46 13:11
Tanner Bibee (R) 5.78 5-13 3.97 123 44 0 27 135 73 69 26 0 1.14 133:99
Slade Cecconi (R) 4.78 4-7 5.07 88 37 0 21 128 68 62 17 0 1.5 116:71
Daniel Espino (R) 1 0 4.5 12 4 0 0 5 3 3 1 0 1.5 3:2
Tim Herrin (L) 0.83 2-4 3.28 42 24 0 0 34 18 17 5 0 1.24 41:27
Doug Nikhazy (L) 0.8 0 14.73 3 4 0 0 8 6 6 0 0 3.27 4:2
Gavin Williams (R) 5.78 12-7 3.98 204 49 0 27 126 72 69 27 0 1.12 128:63
Yorman Gomez (R) 1.55 0 10.8 1 4 0 0 5 4 4 1 0 2.7 5:1
Austin Peterson (R) 1.1 0 27 1 1 0 0 4 4 4 0 0 3.75 2:1
Trenton Denholm (R) 1.55 0-1 13.5 2 2 0 0 7 5 5 1 0 2.7 5:2
Tommy Mace (R) 1 0 6 4 1 0 0 2 2 2 1 0 1 4:1
Ryan Webb (L) 1 1-0 6 4 1 0 0 4 2 2 0 0 1.67 3:2
Zane Petty (R) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 1:0
Foster Griffin (L) 5 3-1 4.05 19 8 0 4 21 11 9 4 0 1.45 17:16
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Bryan Abreu (R) 0.95 5-3 4.17 63 36 0 0 36 25 23 7 0 1.45 37:21
AJ Blubaugh (R) 1.61 4-2 3.17 84 34 0 0 62 31 29 10 0 1.17 58:61
Enyel De Los Santos (R) 1.06 2-3 4.67 57 14 0 0 59 36 32 8 0 1.18 48:40
Josh Hader (L) 0.97 4-1 0.79 46 11 0 0 13 3 3 1 0 0.7 22:18
Steven Okert (L) 1 6-2 2.17 66 14 0 1 44 17 16 7 0 0.87 39:45
Nate Pearson (R) 1.25 1-0 3.6 16 12 0 0 16 10 8 1 0 1.4 17:14
Bennett Sousa (L) 0.83 1-3 6.27 21 10 0 0 24 15 13 2 0 1.82 10:17
Logan VanWey (R) 1.2 1-0 1.5 5 0 0 0 5 2 1 0 0 0.83 5:4
Hayden Wesneski (R) 5.37 4-1 3.86 28 12 0 6 27 14 14 2 0 1.19 28:17
Miguel Ullola (R) 1.5 0 4.5 9 1 0 0 4 3 3 2 0 0.83 2:5
Cody Bolton (R) 2.5 0-1 5.4 22 14 0 3 21 12 12 3 0 1.75 18:11
Sam Carlson (R) 1.28 0 0 7 1 0 0 4 0 0 0 0 0.94 5:3
Michael Knorr (R) 1.03 0 2.7 3 1 0 0 4 2 1 0 0 1.5 3:5
Peter Lambert (R) 5.57 8-7 3.66 125 51 0 23 106 54 52 13 0 1.23 97:92
Hudson Leach (R) 1 0 0 3 0 0 0 2 0 0 0 0 0.67 2:2
Anthony Maldonado (R) 1.02 1-0 2.84 2 1 0 0 3 2 2 1 0 0.63 6:5
Roddery Munoz (R) 1.33 0 15.75 6 6 0 0 7 7 7 3 0 3.25 2:1
Alimber Santa (R) 1.51 0-1 1.17 9 6 0 0 8 6 2 1 0 0.91 19:10
Amos Willingham (R) 1 0-3 10.5 10 4 0 0 9 9 7 1 0 2.17 9:0
Tom Cosgrove (L) 1.03 1-0 2.35 5 2 0 0 3 2 2 1 0 0.65 6:4
Trey McLoughlin (R) 0.5 0 0 0 0 0 0 0 0 0 0 0 0 1:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Franco Aleman (R) 1.01 0 3.38 22 8 0 0 19 7 7 2 0 1.45 8:12
Kolby Allard (L) 2.05 0 10.38 9 3 0 0 16 10 10 2 0 2.19 10:3
Joey Cantillo (L) 4.86 9-7 3.7 145 70 0 28 128 66 56 15 0 1.45 114:77
Matt Festa (R) 0.98 2-3 3.54 62 16 0 0 58 27 22 6 0 1.32 41:25
Hunter Gaddis (R) 0.85 2-3 3.18 44 19 0 0 42 16 16 5 0 1.35 33:35
Erik Sabrowski (L) 0.78 5-2 3 65 25 0 0 24 16 13 3 0 1.26 8:20
Connor Brogdon (R) 1.01 2-2 5.28 14 3 0 0 14 12 9 5 0 1.11 17:12
Colin Holderman (R) 1 6-3 2.25 50 19 0 0 30 14 13 1 0 0.94 57:25
Shawn Armstrong (R) 0.87 2-1 4.91 33 19 0 0 29 19 18 4 0 1.45 26:22
Pedro Avila (R) 1.35 0 3.24 4 1 0 0 10 4 3 1 0 1.32 12:4
Tanner Burns (R) 1 0-1 4.5 2 3 0 0 3 2 2 0 0 1.5 5:2
Codi Heuer (R) 1.15 0-1 4.66 6 5 0 0 12 5 5 0 0 1.76 9:10
Jack Leftwich (R) 0.64 0 0 5 0 0 0 0 0 0 0 0 0 3:2
Jake Miller (R) 0.4 0-1 16.2 3 3 0 0 0 3 3 0 0 1.8 1:0
Peyton Pallette (R) 1.26 1-2 5.23 22 16 0 0 17 13 12 2 0 1.6 18:7
Steven Perez (L) 0.67 0 4.5 3 2 0 0 2 1 1 1 0 2 2:1
Trevor Stephan (R) 0.78 0 2.7 5 4 0 0 3 1 1 0 0 2.1 4:1
Jack Carey (R) 0.5 0 0 0 1 0 0 1 0 0 0 0 2 3:0
Jay Driver (R) 0.75 0 3 2 1 0 0 3 1 1 0 0 1.33 2:5
Magnus Ellerts (R) 0.7 0 3.86 4 0 0 0 1 1 1 1 0 0.43 2:1
Matt Jachec (R) 0.55 0 0 2 1 0 0 0 0 0 0 0 0.75 0:0
Jack Jasiak (R) 0.7 0 3.86 4 0 0 0 2 1 1 0 0 0.86 2:1
Izaak Martinez (L) 0.7 0 0 1 1 0 0 1 0 0 0 0 0.86 3:0
Xavier Martinez (R) 0.6 0 0 1 3 0 0 0 0 0 0 0 1.8 1:2
Zane Morehouse (R) 0.6 0 16.2 2 2 0 0 2 3 3 0 0 2.4 1:2
Cam Schuelke (R) 0.55 1-0 0 5 3 0 0 1 0 0 0 0 1.5 1:2
Hunter Stanley (R) 0.55 0 0 1 1 0 0 0 0 0 0 0 0.38 2:2
Tyler Thornton (R) 0.7 0 19.29 5 4 0 0 2 5 5 2 0 2.57 1:1
Adam Tulloch (L) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Alaska Abney (R) 1 0 0 0 1 0 0 1 0 0 0 0 2 2:1
Ross Carver (R) 1 0 0 0 1 0 0 1 0 0 0 0 2 1:0
Sean Matson (R) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Logan McGuire (R) 0.1 0 0 1 0 0 0 1 0 0 0 0 1.5 0:0
Reid Johnston (R) 0.1 0 0 1 0 0 0 0 0 0 0 0 0 0:0
Craig Yoho (R) 0.91 0-1 6.75 11 6 0 0 11 7 7 2 0 1.82 10:1
Umpire G W-L AVG PIT STR B STR% STR_ BB K/BB HR O/U
Alex Tosi 0 0-0 0 0 0 0 0 0 0 0 0 0-0

Line Up - Last Game

Houston Astros
Pitchers
POS Player
SP Hayden Wesneski
RP Steven Okert
RP AJ Blubaugh
RP Josh Hader
Hitters
POS Player
SS Jeremy Pena
DH Yordan Alvarez
3B Isaac Paredes
2B Jose Altuve
CF Daulton Varsho
1B Christian Walker
C Yainer Diaz
LF Taylor Trammell
RF Cam Smith
Cleveland Guardians
Pitchers
POS Player
Hitters
POS Player
  • HOU
  • CLE
MLB Odds