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Houston Astros vs. Cleveland Guardians Odds, Stats April 22, 2026

Final Score
American League West
Apr 22nd, 1:10 PM EDT
Houston
Astros
Cleveland
Guardians
2
0
Houston Astros
Cleveland Guardians
Scoreboard 1 2 3 4 5 6 7 8 9 R ML H E
Houston Astros 39-43 2 0 0 0 0 0 0 0 - 2 +135 6 1
Cleveland Guardians 42-39 0 0 0 0 0 0 0 0 - 0 -160 5 0

Latest Encounters

Date Result Competition Stats Recap
06/24/26
Houston Astros HOU ( 39-43 )
Toronto Blue Jays TOR ( 39-41 )
3   -   1
 American League West
06/24/26
Cleveland Guardians CLE ( 42-39 )
Chi. White Sox White Sox CHW ( 41-38 )
4   -   3
 American League Central
06/23/26
Cleveland Guardians CLE ( 42-39 )
Chi. White Sox White Sox CHW ( 41-38 )
1   -   2
 American League Central
06/23/26
Houston Astros HOU ( 39-43 )
Toronto Blue Jays TOR ( 39-41 )
9   -   7
 American League West
06/22/26
Cleveland Guardians CLE ( 42-39 )
Chi. White Sox White Sox CHW ( 41-38 )
5   -   6
 American League Central
06/22/26
Houston Astros HOU ( 39-43 )
Toronto Blue Jays TOR ( 39-41 )
2   -   4
 American League West
06/21/26
Cleveland Guardians CLE ( 42-39 )
Houston Astros HOU ( 39-43 )
1   -   2
 American League Central
06/20/26
Cleveland Guardians CLE ( 42-39 )
Houston Astros HOU ( 39-43 )
8   -   1
 American League Central
06/19/26
Cleveland Guardians CLE ( 42-39 )
Houston Astros HOU ( 39-43 )
3   -   9
 American League Central

Matchup Odds

Team Runline Moneyline Over / Under
Houston Astros HOU
+1.5 0 0 U+8.50
Cleveland Guardians CLE
-1.5 0 0 O+8.50

Line History

time fav spread money line total
Opening 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110
Closing 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110

Line History

Team Leaders

Houston Astros HOU
Cleveland Guardians CLE
Yordan Alvarez
Designated Hitter Cleveland
25 HR 11
Angel Martinez
Left Outfield Houston
Austin Hedges
Catcher Houston
0.3 BA 0.3
LaMonte Wade Jr.
First Base Cleveland
Jose Ramirez
Third Base Houston
24 SB 9
Cam Smith
Right Outfield Cleveland

Matchup Details

Houston Astros HOU
Cleveland Guardians CLE
Stat
9 Wins 14
16 Losses 11
6-4 Last 10 4-6
-11.77 Units 5.17
7-6 Wins Home 8-4
2-10 Wins Away 6-7
18-7 Covers Against Ou 13-12
9-16 Run Line Wins Losses 15-10
-7.75 Runline Units 4.15

Recent Meetings

date home-away ats o/u CLE:RBI CLE:Batting Average CLE:Home Runs HOU:RBI HOU:Batting Average HOU:Home Runs
06/21/2026 HOU 2 - CLE 1 HOU Under 8.5 1 .13 0 2 .24 1
06/20/2026 HOU 1 - CLE 8 CLE Over 8.5 8 .29 3 1 .16 0
06/19/2026 HOU 9 - CLE 3 HOU Over 8.5 3 .21 1 8 .33 3
04/22/2026 CLE 0 - HOU 2 HOU Under 8 0 .16 0 2 .19 1
04/21/2026 CLE 8 - HOU 5 CLE Over 8.5 8 .33 1 5 .3 0
04/20/2026 CLE 2 - HOU 9 HOU Over 7 2 .24 0 9 .34 3
07/09/2025 HOU 2 - CLE 4 CLE Under 7.5 4 .19 2 2 .19 0
07/08/2025 HOU 6 - CLE 10 CLE Over 7 10 .22 3 6 .28 0
07/07/2025 HOU 5 - CLE 7 CLE Over 7.5 7 .29 2 5 .16 3
06/08/2025 CLE 4 - HOU 2 CLE Under 7.5 2 .21 0 3 .28 1
06/07/2025 CLE 3 - HOU 5 HOU Over 7 4 .17 1 3 .17 1
06/06/2025 CLE 2 - HOU 4 HOU Under 7.5 4 .29 1 2 .28 1
09/28/2024 CLE 3 - HOU 4 HOU Under 7.5 2 .25 0 3 .26 1
09/27/2024 CLE 2 - HOU 5 HOU Under 8.5 4 .34 2 2 .1 0
05/02/2024 HOU 8 - CLE 2 HOU Over 9 2 .22 0 7 .3 1
05/01/2024 HOU 2 - CLE 3 CLE Under 8.5 3 .26 1 2 .2 1
04/30/2024 HOU 10 - CLE 9 HOU Over 9 9 .19 3 10 .29 3
08/02/2023 HOU 3 - CLE 2 HOU Under 9 2 .22 0 3 .3 2
08/01/2023 HOU 2 - CLE 0 HOU Under 7.5 0 0 0 2 .21 0
07/31/2023 HOU 7 - CLE 3 HOU Over 9.5 3 .28 0 6 .24 1
date score ats o/u RBI Batting Average Home Runs
06/24/2026 TOR 1 - HOU 3 W Under 8.5 2 .13 0
06/23/2026 TOR 7 - HOU 9 W Over 8.5 9 .33 4
06/22/2026 TOR 4 - HOU 2 L Under 7 2 .17 0
06/21/2026 HOU 2 - CLE 1 W Under 8.5 1 .13 0
06/20/2026 HOU 1 - CLE 8 L Over 8.5 8 .29 3
06/19/2026 HOU 9 - CLE 3 W Over 8.5 3 .21 1
06/17/2026 HOU 4 - DET 2 W Under 8.5 2 .1 2
06/16/2026 HOU 4 - DET 2 W Under 8.5 2 .17 0
06/15/2026 HOU 3 - DET 9 L Over 9 8 .29 5
06/14/2026 KC 4 - HOU 0 L Under 8.5 0 .17 0
date score ats o/u RBI Batting Average Home Runs
06/24/2026 CHW 3 - CLE 4 W Under 8 3 .28 2
06/23/2026 CHW 2 - CLE 1 L Under 7 2 .11 1
06/22/2026 CHW 6 - CLE 5 L Over 7.5 6 .29 1
06/21/2026 HOU 2 - CLE 1 L Under 8.5 2 .24 1
06/20/2026 HOU 1 - CLE 8 W Over 8.5 1 .16 0
06/19/2026 HOU 9 - CLE 3 L Over 8.5 8 .33 3
06/18/2026 MIL 2 - CLE 4 W Under 7.5 2 .17 0
06/17/2026 MIL 9 - CLE 4 L Over 7.5 9 .32 2
06/16/2026 MIL 2 - CLE 1 L Under 8 2 .14 2
06/13/2026 CLE 3 - DET 1 W Under 7.5 2 .27 1

Matchup Edge - Scoring Stats

Houston Astros HOU
Cleveland Guardians CLE
avg rank edge in rank avg
4.11 24 Runs Per 9 Innings 5 6.18
0.618 27 On Base Plus Slugging 9 0.819
0.197 24 Batting Average 13 0.256
19 21 Home Runs 3 46

Odds Analysis

Team Rankings

Houston Astros HOU
Season stats rank
ERA 4.76 4
WHIP 1.4 6
KS 674 13
CG - -
Errors 31 7
Cleveland Guardians CLE
Season stats rank
ERA 3.79 25
WHIP 1.25 23
KS 662 20
CG - -
Errors 37 13
Houston Astros HOU
Season stats rank
Runs / G 4.51 15
BA 0.24 20
OPS 0.73 14
HR 107 5
SB 27 28
Cleveland Guardians CLE
Season stats rank
Runs / G 3.95 28
BA 0.23 29
OPS 0.68 28
HR 75 25
SB 72 7

Injuries

Houston Astros HOU
Cleveland Guardians CLE

Houston vs. Cleveland Betting News

Houston Astros HOU

No posts found.
Cleveland Guardians CLE

No posts found.

Houston Vs Cleveland Betting Trends

Houston Astros HOU

Over is 5-1 in Astros last 6 games vs. a right-handed starter.

Under is 5-1 in Astros last 6 Wednesday games.

Over is 7-0 in Astros last 7 games with the total set at 9.0-10.5.

Astros are 19-7 in their last 26 games with the total set at 11.0 or higher.

Over is 10-4 in Astros last 14 games as a favorite.

Cleveland Guardians CLE

Under is 6-1-3 in Guardians last 10 Wednesday games.

Under is 3-1-2 in Guardians last 6 games with the total set at 9.0-10.5.

Guardians are 5-2 in their last 7 games with the total set at 11.0 or higher.

Over is 4-1 in Guardians last 5 games as a favorite.

Guardians are 3-7 in their last 10 when their opponent allows 5 runs or more in their previous game.

Pitchers & Umpires

Today - Overall

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (-) - - - - - - 39-43 - - - - -
Tanner Bibee (-) - - - - - - 42-39 - - - - -

Today - Last 3

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (-) - - - - - - 39-43 - - - - -
Tanner Bibee (-) - - - - - - 42-39 - - - - -
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Jason Alexander (-) 4.53 1-1 9.33 14 8 0 2 21 19 19 4 0 1.58 21:10
Spencer Arrighetti (-) 5.75 7-3 3.13 68 32 0 12 51 26 24 6 0 1.2 59:43
Hunter Brown (-) 4.78 1-0 1.4 28 11 0 4 12 3 3 1 0 1.19 14:8
J.P. France (-) 2.07 0 8.1 4 5 0 0 6 6 6 1 0 1.65 8:6
Colton Gordon (-) 2.28 0 11.57 11 3 0 1 21 12 12 6 0 2.57 7:3
Cristian Javier (-) 3.03 0-1 12.54 4 9 0 3 13 13 13 2 0 2.36 6:10
Lance McCullers Jr. (-) 4.89 2-3 6.86 43 22 0 8 38 32 30 7 0 1.53 32:18
Jayden Murray (-) 1.64 0 7.43 8 7 0 0 19 11 11 1 0 1.95 9:14
Miguel Ullola (-) 1.7 0 10.13 4 6 0 0 6 6 6 3 0 2.25 2:5
Ryan Weiss (-) 2.89 0-3 7.62 30 20 0 2 35 24 22 8 0 2.12 18:12
Mike Burrows (-) 5.32 3-8 5.48 69 31 0 15 97 55 52 19 0 1.5 74:52
Tatsuya Imai (-) 4.1 4-3 6.15 48 24 0 10 35 28 28 6 0 1.44 38:16
Kai-Wei Teng (-) 2.73 4-6 4.03 62 27 0 9 51 30 27 9 0 1.29 56:29
Amilcar Chirinos (R) 0.2 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Wilmy Sanchez (-) 2 0 0 3 0 0 0 0 0 0 0 0 0 2:1
Trey Dombroski (-) 1.05 0-1 11.57 1 0 0 0 3 3 3 2 0 1.29 1:3
Joey Mancini (-) 2 0 0 1 2 0 0 0 0 0 0 0 1 2:0
Alex Santos II (-) 0.1 0 0 0 0 0 0 1 0 0 0 0 3 0:1
Nolan DeVos (-) 2 0 0 1 0 0 0 1 0 0 0 0 0.5 4:1
Dylan Howard (-) 2 0 0 2 1 0 0 2 0 0 0 0 1.5 2:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Logan Allen (-) 4 0 0 7 1 0 0 5 2 0 0 0 1.5 3:3
Tanner Bibee (-) 5.57 2-8 4.03 78 28 0 16 77 41 40 16 0 1.18 77:53
Slade Cecconi (-) 5.26 3-6 4.48 66 27 0 16 91 44 42 12 0 1.4 89:56
Daniel Espino (-) 1 0 9 4 0 0 0 3 2 2 1 0 1.5 0:2
Parker Messick (-) 5.88 7-4 2.67 101 29 0 16 70 30 28 9 0 1.05 84:38
Doug Nikhazy (-) 0.8 0 14.73 3 4 0 0 8 6 6 0 0 3.27 4:2
Gavin Williams (-) 6.01 9-4 3.82 111 31 0 16 79 43 41 15 0 1.14 89:40
Yorman Gomez (-) 1.55 0 10.8 1 4 0 0 5 4 4 1 0 2.7 5:1
Austin Peterson (-) 1.1 0 27 1 1 0 0 4 4 4 0 0 3.75 2:1
Trenton Denholm (-) 1.55 0-1 13.5 2 2 0 0 7 5 5 1 0 2.7 5:2
Tommy Mace (-) 1 0 6 4 1 0 0 2 2 2 1 0 1 4:1
Ryan Webb (-) 1 1-0 6 4 1 0 0 4 2 2 0 0 1.67 3:2
Zane Petty (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 1:0
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Bryan Abreu (-) 0.87 2-3 6.39 33 24 0 0 22 20 18 6 0 1.82 18:12
AJ Blubaugh (-) 1.59 3-2 3.81 45 29 0 0 35 22 21 5 0 1.29 38:38
Enyel De Los Santos (-) 1.04 0-2 4.67 33 8 0 0 32 19 18 3 0 1.15 23:25
Josh Hader (-) 1 1-0 0.9 16 2 0 0 2 1 1 1 0 0.4 6:3
Bryan King (-) 1.06 2-1 2.38 26 14 0 0 29 11 9 1 0 1.26 36:16
Steven Okert (-) 1 1-0 2.35 36 11 0 1 24 10 10 3 0 0.91 21:27
Nate Pearson (-) 1.12 1-0 3.86 12 5 0 0 12 7 5 1 0 1.46 7:9
Bennett Sousa (-) 0.62 0 8.1 4 5 0 0 3 3 3 0 0 2.4 1:3
Logan VanWey (-) 1.2 1-0 1.5 5 0 0 0 5 2 1 0 0 0.83 5:4
Cody Bolton (-) 2.5 0-1 5.4 22 14 0 3 21 12 12 3 0 1.75 18:11
Sam Carlson (-) 1.28 0 0 7 1 0 0 4 0 0 0 0 0.94 5:3
Michael Knorr (-) 1.03 0 2.7 3 1 0 0 4 2 1 0 0 1.5 3:5
Peter Lambert (-) 5.68 6-4 3.28 64 28 0 12 52 25 25 7 0 1.17 57:51
Hudson Leach (-) 1 0 0 3 0 0 0 2 0 0 0 0 0.67 2:2
Anthony Maldonado (-) 1.02 1-0 2.84 2 1 0 0 3 2 2 1 0 0.63 6:5
Roddery Munoz (-) 1.33 0 15.75 6 6 0 0 7 7 7 3 0 3.25 2:1
Alimber Santa (-) 1.53 0-1 0.71 8 5 0 0 5 5 1 0 0 0.79 15:9
Amos Willingham (-) 1 0-3 10.5 10 4 0 0 9 9 7 1 0 2.17 9:0
Tom Cosgrove (-) 1.03 1-0 2.35 5 2 0 0 3 2 2 1 0 0.65 6:4
Trey McLoughlin (-) 0.5 0 0 0 0 0 0 0 0 0 0 0 0 1:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Franco Aleman (-) 1.1 0 3.38 1 1 0 0 3 1 1 1 0 1.5 2:1
Kolby Allard (-) 2.05 0 10.38 9 3 0 0 16 10 10 2 0 2.19 10:3
Joey Cantillo (-) 5 6-3 4.05 76 37 0 16 75 40 36 11 0 1.4 68:56
Matt Festa (-) 0.97 1-1 4.22 35 9 0 0 30 16 15 6 0 1.22 23:15
Hunter Gaddis (-) 0.84 1-2 3.8 17 8 0 0 24 9 9 3 0 1.5 19:16
Tim Herrin (-) 0.79 0-2 3.08 24 17 0 0 20 10 9 3 0 1.41 21:15
Erik Sabrowski (-) 0.81 2-1 2.53 40 14 0 0 8 6 6 1 0 1.03 3:9
Cade Smith (-) 1.07 2-1 2.78 54 9 0 0 30 13 11 1 0 1.09 22:18
Connor Brogdon (-) 1.01 2-2 5.28 14 3 0 0 14 12 9 5 0 1.11 17:12
Colin Holderman (-) 1.08 4-1 1.61 32 9 0 0 13 6 5 1 0 0.79 26:12
Shawn Armstrong (-) 0.88 1-1 3.32 24 10 0 0 16 9 8 2 0 1.2 16:14
Pedro Avila (-) 1.35 0 3.24 4 1 0 0 10 4 3 1 0 1.32 12:4
Tanner Burns (-) 1 0-1 4.5 2 3 0 0 3 2 2 0 0 1.5 5:2
Will Dion (-) 1.85 0 5.56 13 3 0 0 18 11 7 2 0 1.85 8:6
Codi Heuer (-) 1.14 0-1 5.63 6 5 0 0 10 5 5 0 0 1.88 7:8
Jack Leftwich (-) 0.64 0 0 5 0 0 0 0 0 0 0 0 0 3:2
Jake Miller (-) 0.4 0-1 16.2 3 3 0 0 0 3 3 0 0 1.8 1:0
Peyton Pallette (-) 1.26 1-2 5.23 22 16 0 0 17 13 12 2 0 1.6 18:7
Steven Perez (-) 0.67 0 4.5 3 2 0 0 2 1 1 1 0 2 2:1
Trevor Stephan (-) 0.78 0 2.7 5 4 0 0 3 1 1 0 0 2.1 4:1
Jack Carey (-) 0.5 0 0 0 1 0 0 1 0 0 0 0 2 3:0
Jay Driver (-) 0.75 0 3 2 1 0 0 3 1 1 0 0 1.33 2:5
Magnus Ellerts (-) 0.7 0 3.86 4 0 0 0 1 1 1 1 0 0.43 2:1
Matt Jachec (-) 0.55 0 0 2 1 0 0 0 0 0 0 0 0.75 0:0
Jack Jasiak (-) 0.7 0 3.86 4 0 0 0 2 1 1 0 0 0.86 2:1
Izaak Martinez (-) 0.7 0 0 1 1 0 0 1 0 0 0 0 0.86 3:0
Xavier Martinez (-) 0.6 0 0 1 3 0 0 0 0 0 0 0 1.8 1:2
Zane Morehouse (-) 0.6 0 16.2 2 2 0 0 2 3 3 0 0 2.4 1:2
Cam Schuelke (-) 0.55 1-0 0 5 3 0 0 1 0 0 0 0 1.5 1:2
Hunter Stanley (-) 0.55 0 0 1 1 0 0 0 0 0 0 0 0.38 2:2
Tyler Thornton (-) 0.7 0 19.29 5 4 0 0 2 5 5 2 0 2.57 1:1
Adam Tulloch (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Alaska Abney (-) 1 0 0 0 1 0 0 1 0 0 0 0 2 2:1
Ross Carver (-) 1 0 0 0 1 0 0 1 0 0 0 0 2 1:0
Sean Matson (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Logan McGuire (-) 0.1 0 0 1 0 0 0 1 0 0 0 0 1.5 0:0
Reid Johnston (-) 0.1 0 0 1 0 0 0 0 0 0 0 0 0 0:0
Umpire G W-L AVG PIT STR B STR% STR_ BB K/BB HR O/U
Alex Tosi 0 0-0 0 0 0 0 0 0 0 0 0 0-0

Line Up - Last Game

Houston Astros
Pitchers
POS Player
SP Mike Burrows
RP Steven Okert
RP Bryan King
RP Josh Hader
Hitters
POS Player
2B Jose Altuve
DH Yordan Alvarez
SS Jeremy Pena
1B Isaac Paredes
LF Joey Loperfido
C Yainer Diaz
RF Cam Smith
CF Brice Matthews
3B Raynel Delgado
Cleveland Guardians
Pitchers
POS Player
Hitters
POS Player
  • HOU
  • CLE
MLB Odds