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Houston Astros vs. Cleveland Guardians Odds, Stats - April 22, 2026

Final Score
American League West
Apr 22nd, 1:10 PM EDT
Houston
Astros
Cleveland
Guardians
2
0
Houston Astros
Cleveland Guardians
Scoreboard 1 2 3 4 5 6 7 8 9 R ML H E
Houston Astros 20-31 2 0 0 0 0 0 0 0 - 2 +135 6 1
Cleveland Guardians 29-22 0 0 0 0 0 0 0 0 - 0 -160 5 0

Latest Encounters

Date Result Competition Stats Recap
05/20/26
Cleveland Guardians CLE ( 29-22 )
Detroit Tigers DET ( 20-30 )
3   -   2
 American League Central
05/20/26
Houston Astros HOU ( 20-31 )
Minnesota Twins MIN ( 23-27 )
1   -   4
 American League West
05/19/26
Houston Astros HOU ( 20-31 )
Minnesota Twins MIN ( 23-27 )
2   -   1
 American League West
05/19/26
Cleveland Guardians CLE ( 29-22 )
Detroit Tigers DET ( 20-30 )
4   -   3
 American League Central
05/18/26
Houston Astros HOU ( 20-31 )
Minnesota Twins MIN ( 23-27 )
3   -   6
 American League West
05/18/26
Cleveland Guardians CLE ( 29-22 )
Detroit Tigers DET ( 20-30 )
8   -   2
 American League Central
05/17/26
Texas Rangers TEX ( 24-25 )
Houston Astros HOU ( 20-31 )
8   -   0
 American League West
05/17/26
Cincinnati Reds CIN ( 26-24 )
Cleveland Guardians CLE ( 29-22 )
3   -   10
 National League Central
05/16/26
Texas Rangers TEX ( 24-25 )
Houston Astros HOU ( 20-31 )
1   -   4
 American League West
05/16/26
Cincinnati Reds CIN ( 26-24 )
Cleveland Guardians CLE ( 29-22 )
4   -   7
 National League Central
05/15/26
Texas Rangers TEX ( 24-25 )
Houston Astros HOU ( 20-31 )
0   -   2
 American League West
05/15/26
Cincinnati Reds CIN ( 26-24 )
Cleveland Guardians CLE ( 29-22 )
7   -   6
 National League Central

Matchup Odds

Team Runline Moneyline Over / Under
Houston Astros HOU
+1.5 0 0 U+8.50
Cleveland Guardians CLE
-1.5 0 0 O+8.50

Line History

time fav line total
Opening 21 Apr 11:43pm HOU O +8 -110
Closing 22 Apr 7:29pm HOU U +2.5 -130

Line History

Team Leaders

Houston Astros HOU
Cleveland Guardians CLE
Yordan Alvarez
Designated Hitter Cleveland
15 HR 9
Angel Martinez
Left Outfield Houston
Travis Bazzana
Second Base Houston
0.3 BA 0.3
Taylor Trammell
Left Outfield Cleveland
Jose Ramirez
Third Base Houston
20 SB 6
Cam Smith
Right Outfield Cleveland

Matchup Details

team win loss last 10 units home away o / u rl w/l rl units
Houston Astros Houston Astros
9 16 4-6 -11.77 7-6 2-10 18-7 9-16 -7.75
Cleveland Guardians Cleveland Guardians
14 11 8-2 5.17 8-4 6-7 13-12 15-10 4.15

Recent Meetings

date home-away ats o/u CLE:RBI CLE:Batting Average CLE:Home Runs HOU:RBI HOU:Batting Average HOU:Home Runs
04/22/2026 CLE 0 - HOU 2 HOU Under 8 0 .16 0 2 .19 1
04/21/2026 CLE 8 - HOU 5 CLE Over 8.5 8 .33 1 5 .3 0
04/20/2026 CLE 2 - HOU 9 HOU Over 7 2 .24 0 9 .34 3
07/09/2025 HOU 2 - CLE 4 CLE Under 7.5 4 .19 2 2 .19 0
07/08/2025 HOU 6 - CLE 10 CLE Over 7 10 .22 3 6 .28 0
07/07/2025 HOU 5 - CLE 7 CLE Over 7.5 7 .29 2 5 .16 3
06/08/2025 CLE 4 - HOU 2 CLE Under 7.5 2 .21 0 3 .28 1
06/07/2025 CLE 3 - HOU 5 HOU Over 7 4 .17 1 3 .17 1
06/06/2025 CLE 2 - HOU 4 HOU Under 7.5 4 .29 1 2 .28 1
09/28/2024 CLE 3 - HOU 4 HOU Under 7.5 2 .25 0 3 .26 1
09/27/2024 CLE 2 - HOU 5 HOU Under 8.5 4 .34 2 2 .1 0
05/02/2024 HOU 8 - CLE 2 HOU Over 9 2 .22 0 7 .3 1
05/01/2024 HOU 2 - CLE 3 CLE Under 8.5 3 .26 1 2 .2 1
04/30/2024 HOU 10 - CLE 9 HOU Over 9 9 .19 3 10 .29 3
08/02/2023 HOU 3 - CLE 2 HOU Under 9 2 .22 0 3 .3 2
08/01/2023 HOU 2 - CLE 0 HOU Under 7.5 0 0 0 2 .21 0
07/31/2023 HOU 7 - CLE 3 HOU Over 9.5 3 .28 0 6 .24 1
06/11/2023 CLE 5 - HOU 0 CLE Under 8 0 .13 0 5 .35 2
06/10/2023 CLE 4 - HOU 6 HOU Over 8 6 .27 1 4 .3 0
06/09/2023 CLE 10 - HOU 9 CLE Over 8 9 .29 1 9 .27 1
date score ats o/u RBI Batting Average Home Runs
05/20/2026 MIN 4 - HOU 1 L Over 0 1 .16 0
05/19/2026 MIN 1 - HOU 2 W Over 0 2 .16 1
05/18/2026 MIN 6 - HOU 3 L Over 0 3 .23 0
05/17/2026 HOU 0 - TEX 8 L Over 0 8 .21 2
05/16/2026 HOU 4 - TEX 1 W Over 0 1 .19 0
05/15/2026 HOU 2 - TEX 0 W Over 0 0 .04 0
05/14/2026 HOU 3 - SEA 8 L Over 0 8 .3 2
05/13/2026 HOU 4 - SEA 3 W Over 0 3 .22 2
05/12/2026 HOU 2 - SEA 10 L Over 0 10 .31 2
05/11/2026 HOU 1 - SEA 3 L Over 0 3 .21 1
date score ats o/u RBI Batting Average Home Runs
05/20/2026 DET 2 - CLE 3 W Over 0 2 .15 0
05/19/2026 DET 3 - CLE 4 W Over 0 2 .21 1
05/18/2026 DET 2 - CLE 8 W Over 0 2 .17 1
05/17/2026 CLE 10 - CIN 3 W Over 0 10 .34 6
05/16/2026 CLE 7 - CIN 4 W Over 0 5 .29 1
05/15/2026 CLE 6 - CIN 7 L Over 0 6 .24 1
05/13/2026 CLE 4 - LAA 2 W Over 0 4 .21 1
05/12/2026 CLE 3 - LAA 2 W Over 0 3 .15 1
05/11/2026 CLE 7 - LAA 2 W Over 0 7 .23 0
05/10/2026 CLE 4 - MIN 5 L Over 7.5 4 .31 0

Matchup Edge - Scoring Stats

Houston Astros HOU
Cleveland Guardians CLE
avg rank edge in rank avg
4.4 17 Runs Per 9 Innings 14 4.48
0.724 9 On Base Plus Slugging 14 0.703
0.246 7 Batting Average 18 0.231
60 8 Home Runs 13 52

Odds Analysis

Team Rankings

offence
Houston Astros HOU
Season stats rank
Runs / G 4.27 18
BA 0.25 10
OPS 0.72 10
HR 60 8
SB 17 29
Cleveland Guardians CLE
Season stats rank
Runs / G 4.41 15
BA 0.23 24
OPS 0.7 19
HR 52 16
SB 53 3
defence
Houston Astros HOU
Season stats rank
Runs / G 4.27 18
BA 0.25 10
OPS 0.72 10
HR 60 8
SB 17 29
Cleveland Guardians CLE
Season stats rank
Runs / G 4.41 15
BA 0.23 24
OPS 0.7 19
HR 52 16
SB 53 3

Injuries

Houston Astros HOU
Cleveland Guardians CLE

Houston vs. Cleveland Betting News

Houston Astros HOU

No posts found.
Cleveland Guardians CLE

No posts found.

Houston Vs Cleveland Betting Trends

Houston Astros HOU

Over is 5-1 in Astros last 6 games vs. a right-handed starter.

Under is 5-1 in Astros last 6 Wednesday games.

Over is 7-0 in Astros last 7 games with the total set at 9.0-10.5.

Astros are 19-7 in their last 26 games with the total set at 11.0 or higher.

Over is 10-4 in Astros last 14 games as a favorite.

Cleveland Guardians CLE

Under is 6-1-3 in Guardians last 10 Wednesday games.

Under is 3-1-2 in Guardians last 6 games with the total set at 9.0-10.5.

Guardians are 5-2 in their last 7 games with the total set at 11.0 or higher.

Over is 4-1 in Guardians last 5 games as a favorite.

Guardians are 3-7 in their last 10 when their opponent allows 5 runs or more in their previous game.

Pitchers & Umpires

Today - Overall

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (-) - - - - - - 20-31 - - - - -
Tanner Bibee (-) - - - - - - 29-22 - - - - -

Today - Last 3

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (-) - - - - - - 20-31 - - - - -
Tanner Bibee (-) - - - - - - 29-22 - - - - -
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Jason Alexander (-) 4.03 1-0 7.3 10 6 0 1 15 10 10 2 0 1.7 13:5
Spencer Arrighetti (-) 6 5-1 1.5 35 21 0 6 22 8 6 1 0 1.19 31:25
Hunter Brown (-) 5.1 1-0 0.84 17 6 0 2 5 1 1 0 0 1.03 6:5
J.P. France (-) 2.07 0 8.1 4 5 0 0 6 6 6 1 0 1.65 8:6
Colton Gordon (-) 2.28 0 11.57 11 3 0 1 21 12 12 6 0 2.57 7:3
Cristian Javier (-) 3.03 0-1 12.54 4 9 0 3 13 13 13 2 0 2.36 6:10
Lance McCullers Jr. (-) 4.89 2-3 6.86 43 22 0 8 38 32 30 7 0 1.53 32:18
Jayden Murray (-) 1.59 0 7.15 5 7 0 0 16 9 9 0 0 2.03 9:13
Miguel Ullola (-) 1.7 0 10.13 4 6 0 0 6 6 6 3 0 2.25 2:5
Ryan Weiss (-) 2.89 0-3 7.62 30 20 0 2 35 24 22 8 0 2.12 18:12
Mike Burrows (-) 5.61 2-6 5.75 48 20 0 10 66 36 36 12 0 1.53 46:34
Tatsuya Imai (-) 3.42 1-2 8.31 21 14 0 5 17 16 16 4 0 1.79 19:6
Kai-Wei Teng (-) 1.94 2-3 2.61 30 12 0 3 22 9 9 3 0 1.1 29:17
Amilcar Chirinos (R) 0.2 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Wilmy Sanchez (-) 2 0 0 3 0 0 0 0 0 0 0 0 0 2:1
Trey Dombroski (-) 1.05 0-1 11.57 1 0 0 0 3 3 3 2 0 1.29 1:3
Joey Mancini (-) 2 0 0 1 2 0 0 0 0 0 0 0 1 2:0
Alex Santos II (-) 0.1 0 0 0 0 0 0 1 0 0 0 0 3 0:1
Nolan DeVos (-) 2 0 0 1 0 0 0 1 0 0 0 0 0.5 4:1
Dylan Howard (-) 2 0 0 2 1 0 0 2 0 0 0 0 1.5 2:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Logan Allen (-) 2.5 0-2 18 9 8 0 4 25 20 20 4 0 3.3 9:6
Tanner Bibee (-) 5.45 0-6 3.75 52 21 0 11 54 25 25 7 0 1.25 50:34
Slade Cecconi (-) 5.21 3-4 5.16 42 19 0 10 59 32 30 9 0 1.49 52:36
Daniel Espino (-) 1 0 0 3 0 0 1 1 0 0 0 0 0.5 1:0
Parker Messick (-) 5.82 5-1 2.45 64 17 0 10 43 17 16 6 0 1.02 49:21
Doug Nikhazy (-) 0.8 0 14.73 3 4 0 0 8 6 6 0 0 3.27 4:2
Gavin Williams (-) 6.11 6-3 3.67 73 22 0 10 51 26 25 9 0 1.19 56:22
Yorman Gomez (-) 1.55 0 10.8 1 4 0 0 5 4 4 1 0 2.7 5:1
Austin Peterson (-) 1.1 0 27 1 1 0 0 4 4 4 0 0 3.75 2:1
Trenton Denholm (-) 1.55 0-1 13.5 2 2 0 0 7 5 5 1 0 2.7 5:2
Tommy Mace (-) 1 0 6 4 1 0 0 2 2 2 1 0 1 4:1
Ryan Webb (-) 1 1-0 6 4 1 0 0 4 2 2 0 0 1.67 3:2
Zane Petty (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 1:0
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Bryan Abreu (-) 0.89 2-2 7.63 21 18 0 0 14 14 13 4 0 2.09 13:7
AJ Blubaugh (-) 1.46 2-2 4.55 24 20 0 0 22 15 15 4 0 1.42 22:24
Enyel De Los Santos (-) 1.01 0-1 4.91 16 4 0 0 20 10 10 1 0 1.31 11:17
Bryan King (-) 1.17 0-1 3 17 9 0 0 20 9 7 0 0 1.38 25:9
Steven Okert (-) 0.91 0 3.43 19 7 0 1 15 8 8 2 0 1.05 16:13
Nate Pearson (-) 1 0 0 0 0 0 0 0 0 0 0 0 0 1:1
Bennett Sousa (-) 0.62 0 8.1 4 5 0 0 3 3 3 0 0 2.4 1:3
Logan VanWey (-) 1 0 0 3 0 0 0 1 0 0 0 0 0.5 0:1
Cody Bolton (-) 2.5 0-1 5.4 22 14 0 3 21 12 12 3 0 1.75 18:11
Sam Carlson (-) 1.28 0 0 7 1 0 0 4 0 0 0 0 0.94 5:3
Michael Knorr (-) 1.03 0 2.7 3 1 0 0 4 2 1 0 0 1.5 3:5
Peter Lambert (-) 5.85 2-4 3.57 35 14 0 6 24 14 14 2 0 1.08 34:21
Hudson Leach (-) 1 0 0 3 0 0 0 2 0 0 0 0 0.67 2:2
Anthony Maldonado (-) 1.02 1-0 2.84 2 1 0 0 3 2 2 1 0 0.63 6:5
Roddery Munoz (-) 1.33 0 15.75 6 6 0 0 7 7 7 3 0 3.25 2:1
Alimber Santa (-) 1 0 3.6 6 6 0 0 5 2 2 0 0 2.2 8:0
Amos Willingham (-) 1 0-3 10.5 10 4 0 0 9 9 7 1 0 2.17 9:0
Tom Cosgrove (-) 1.03 1-0 2.35 5 2 0 0 3 2 2 1 0 0.65 6:4
Trey McLoughlin (-) 0.5 0 0 0 0 0 0 0 0 0 0 0 0 1:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Franco Aleman (-) 1.1 0 3.38 1 1 0 0 3 1 1 1 0 1.5 2:1
Kolby Allard (-) 2.05 0 10.38 9 3 0 0 16 10 10 2 0 2.19 10:3
Joey Cantillo (-) 5.01 3-1 3.4 45 24 0 10 44 23 19 6 0 1.35 43:32
Matt Festa (-) 1 1-0 4.71 21 5 0 0 19 12 11 4 0 1.14 12:14
Hunter Gaddis (-) 0.79 1-1 5.73 8 6 0 0 14 7 7 2 0 1.82 11:9
Tim Herrin (-) 0.76 0-1 1.15 11 11 0 0 13 3 2 0 0 1.53 15:11
Erik Sabrowski (-) 0.84 2-1 1.71 39 13 0 0 7 4 4 1 0 0.95 3:9
Cade Smith (-) 1.01 2-0 2.66 35 5 0 0 22 9 7 1 0 1.14 13:12
Connor Brogdon (-) 1.01 2-2 5.28 14 3 0 0 14 12 9 5 0 1.11 17:12
Colin Holderman (-) 1.38 2-0 1.5 21 4 0 0 9 4 3 1 0 0.72 15:8
Shawn Armstrong (-) 0.85 1-0 4.22 13 7 0 0 8 5 5 2 0 1.41 6:6
Pedro Avila (-) 1.35 0 3.24 4 1 0 0 10 4 3 1 0 1.32 12:4
Tanner Burns (-) 1 0-1 4.5 2 3 0 0 3 2 2 0 0 1.5 5:2
Will Dion (-) 1.22 0 2.84 5 0 0 0 8 2 2 0 0 1.26 6:4
Codi Heuer (-) 2 0 4.5 2 1 0 0 3 1 1 0 0 2 1:1
Jack Leftwich (-) 0.64 0 0 5 0 0 0 0 0 0 0 0 0 3:2
Jake Miller (-) 0.4 0-1 16.2 3 3 0 0 0 3 3 0 0 1.8 1:0
Peyton Pallette (-) 1.28 1-2 5.49 21 13 0 0 17 13 12 2 0 1.53 17:7
Steven Perez (-) 0.67 0 4.5 3 2 0 0 2 1 1 1 0 2 2:1
Trevor Stephan (-) 0.78 0 2.7 5 4 0 0 3 1 1 0 0 2.1 4:1
Jack Carey (-) 0.5 0 0 0 1 0 0 1 0 0 0 0 2 3:0
Jay Driver (-) 0.75 0 3 2 1 0 0 3 1 1 0 0 1.33 2:5
Magnus Ellerts (-) 0.7 0 3.86 4 0 0 0 1 1 1 1 0 0.43 2:1
Matt Jachec (-) 0.55 0 0 2 1 0 0 0 0 0 0 0 0.75 0:0
Jack Jasiak (-) 0.7 0 3.86 4 0 0 0 2 1 1 0 0 0.86 2:1
Izaak Martinez (-) 0.7 0 0 1 1 0 0 1 0 0 0 0 0.86 3:0
Xavier Martinez (-) 0.6 0 0 1 3 0 0 0 0 0 0 0 1.8 1:2
Zane Morehouse (-) 0.6 0 16.2 2 2 0 0 2 3 3 0 0 2.4 1:2
Cam Schuelke (-) 0.55 1-0 0 5 3 0 0 1 0 0 0 0 1.5 1:2
Hunter Stanley (-) 0.55 0 0 1 1 0 0 0 0 0 0 0 0.38 2:2
Tyler Thornton (-) 0.7 0 19.29 5 4 0 0 2 5 5 2 0 2.57 1:1
Adam Tulloch (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Alaska Abney (-) 1 0 0 0 1 0 0 1 0 0 0 0 2 2:1
Ross Carver (-) 1 0 0 0 1 0 0 1 0 0 0 0 2 1:0
Sean Matson (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Logan McGuire (-) 0.1 0 0 1 0 0 0 1 0 0 0 0 1.5 0:0
Reid Johnston (-) 0.1 0 0 1 0 0 0 0 0 0 0 0 0 0:0
Umpire G W-L AVG PIT STR B STR% STR_ BB K/BB HR O/U
Alex Tosi 0 0-0 0 0 0 0 0 0 0 0 0 0-0

Line Up - Last Game

Houston Astros
Pitchers
POS Player
SP Mike Burrows
RP AJ Blubaugh
RP Nate Pearson
Hitters
POS Player
SS Jeremy Pena
3B Isaac Paredes
DH Yordan Alvarez
1B Christian Walker
CF Jake Meyers
LF Zach Dezenzo
2B Brice Matthews
RF Cam Smith
C Cesar Salazar
Cleveland Guardians
Pitchers
POS Player
SP Casey Mize
Hitters
POS Player
CF Matt Vierling
3B Kevin McGonigle
C Dillon Dingler
LF Riley Greene
DH Jahmai Jones
1B Spencer Torkelson
RF Wenceel Perez
2B Hao Yu Lee
SS Zack Short
  • HOU
  • CLE
MLB Odds