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Houston Astros vs. Cleveland Guardians Odds, Stats April 22, 2026

Final Score
American League West
Apr 22nd, 1:10 PM EDT
Houston
Astros
Cleveland
Guardians
2
0
Houston Astros
Cleveland Guardians
Scoreboard 1 2 3 4 5 6 7 8 9 R ML H E
Houston Astros 77-79 2 0 0 0 0 0 0 0 - 2 +135 6 1
Cleveland Guardians 81-75 0 0 0 0 0 0 0 0 - 0 -160 5 0
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Latest Encounters

Date Result Competition Stats Recap
09/20/26
Atlanta Braves ATL ( 92-64 )
Houston Astros HOU ( 77-79 )
4   -   2
 National League East
09/20/26
Athletics Athletics ATH ( 61-95 )
Cleveland Guardians CLE ( 81-75 )
0   -   1
 American League West
09/19/26
Atlanta Braves ATL ( 92-64 )
Houston Astros HOU ( 77-79 )
6   -   3
 National League East

Matchup Odds

Team Runline Moneyline Over / Under
Houston Astros HOU
+1.5 0 0 U+8.50
Cleveland Guardians CLE
-1.5 0 0 O+8.50

Line History

time fav spread money line total
Opening 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110
Closing 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110

Line History

Team Leaders

Houston Astros HOU
Cleveland Guardians CLE
Yordan Alvarez
Designated Hitter Cleveland
40 HR 17
Angel Martinez
Left Outfield Houston
Chase DeLauter
Right Outfield Houston
0.3 BA 0.3
Yordan Alvarez
Designated Hitter Cleveland
Jose Ramirez
Third Base Houston
35 SB 11
Cam Smith
Right Outfield Cleveland

Matchup Details

Houston Astros HOU
Cleveland Guardians CLE
Stat
9 Wins 14
16 Losses 11
3-7 Last 10 7-3
-11.77 Units 5.17
7-6 Wins Home 8-4
2-10 Wins Away 6-7
18-7 Covers Against Ou 13-12
9-16 Run Line Wins Losses 15-10
-7.75 Runline Units 4.15

Odds Analysis

Team Rankings

Houston Astros HOU
Season stats rank
ERA 4.53 7
WHIP 1.34 9
KS 1282 19
CG - -
Errors 70 9
Cleveland Guardians CLE
Season stats rank
ERA 3.77 23
WHIP 1.26 23
KS 1233 25
CG - -
Errors 82 17
Houston Astros HOU
Season stats rank
Runs / G 4.41 19
BA 0.24 19
OPS 0.72 14
HR 209 3
SB 46 30
Cleveland Guardians CLE
Season stats rank
Runs / G 4.16 26
BA 0.24 24
OPS 0.69 28
HR 152 27
SB 142 7

Injuries

Houston Astros HOU
Cleveland Guardians CLE

Houston vs. Cleveland Betting News

Houston Astros HOU

No posts found.
Cleveland Guardians CLE

No posts found.

Houston Vs Cleveland Betting Trends

Houston Astros HOU

Over is 5-1 in Astros last 6 games vs. a right-handed starter.

Under is 5-1 in Astros last 6 Wednesday games.

Over is 7-0 in Astros last 7 games with the total set at 9.0-10.5.

Astros are 19-7 in their last 26 games with the total set at 11.0 or higher.

Over is 10-4 in Astros last 14 games as a favorite.

Cleveland Guardians CLE

Under is 6-1-3 in Guardians last 10 Wednesday games.

Under is 3-1-2 in Guardians last 6 games with the total set at 9.0-10.5.

Guardians are 5-2 in their last 7 games with the total set at 11.0 or higher.

Over is 4-1 in Guardians last 5 games as a favorite.

Guardians are 3-7 in their last 10 when their opponent allows 5 runs or more in their previous game.

Pitchers & Umpires

Today - Overall

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (R) - - - - - - 77-79 - - - - -
Tanner Bibee (R) - - - - - - 81-75 - - - - -

Today - Last 3

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (R) - - - - - - 77-79 - - - - -
Tanner Bibee (R) - - - - - - 81-75 - - - - -
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Jason Alexander (R) 4.53 1-1 9.33 14 8 0 2 21 19 19 4 0 1.58 21:10
Spencer Arrighetti (R) 5.18 7-5 4.6 87 50 0 17 68 47 45 12 0 1.34 69:53
Ronel Blanco (R) 4.46 0-1 7.11 26 15 0 5 30 25 25 9 0 1.42 25:25
Hunter Brown (R) 5.37 6-3 3.26 120 51 0 19 79 40 37 11 0 1.27 108:40
J.P. France (R) 2.07 0 8.1 4 5 0 0 6 6 6 1 0 1.65 8:6
Colton Gordon (L) 2.28 0 11.57 11 3 0 1 21 12 12 6 0 2.57 7:3
Cristian Javier (R) 3.81 2-6 5.31 57 26 0 11 63 36 36 10 0 1.46 32:58
Bryan King (L) 1 3-6 5.4 46 22 0 1 66 39 35 9 0 1.51 73:24
Lance McCullers Jr. (R) 4.89 2-3 6.86 43 22 0 8 38 32 30 7 0 1.53 32:18
Jayden Murray (R) 1.64 0 7.43 8 7 0 0 19 11 11 1 0 1.95 9:14
Ryan Weiss (R) 2.89 0-3 7.62 30 20 0 2 35 24 22 8 0 2.12 18:12
Mike Burrows (R) 5.23 4-9 5.99 75 35 0 17 112 69 63 21 0 1.55 85:60
Tatsuya Imai (R) 3.42 6-4 5 96 51 0 15 58 42 42 9 0 1.44 60:36
Kai-Wei Teng (R) 2.44 5-7 4.76 73 33 0 10 69 43 39 10 0 1.38 64:37
Ethan Pecko (R) 4.7 1-0 3.77 19 12 0 4 20 13 12 5 0 1.12 25:20
Amilcar Chirinos (R) 0.2 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Wilmy Sanchez (R) 2 0 0 3 0 0 0 0 0 0 0 0 0 2:1
Trey Dombroski (L) 1.05 0-1 11.57 1 0 0 0 3 3 3 2 0 1.29 1:3
Joey Mancini (R) 2 0 0 1 2 0 0 0 0 0 0 0 1 2:0
Alex Santos II (R) 0.1 0 0 0 0 0 0 1 0 0 0 0 3 0:1
Nolan DeVos (R) 2 0 0 1 0 0 0 1 0 0 0 0 0.5 4:1
Dylan Howard (R) 2 0 0 2 1 0 0 2 0 0 0 0 1.5 2:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Logan Allen (L) 2.31 0 5.94 16 6 0 2 23 14 11 3 0 1.74 18:14
Tanner Bibee (R) 5.69 6-15 4.35 142 54 0 32 168 92 88 29 0 1.22 153:118
Slade Cecconi (R) 4.44 5-7 4.95 99 39 0 21 134 72 66 19 0 1.44 124:78
Daniel Espino (R) 1.09 0 4.73 22 7 0 2 12 7 7 3 0 1.43 11:5
Tim Herrin (L) 0.85 3-4 2.98 51 28 0 0 41 21 18 5 0 1.27 49:31
Doug Nikhazy (L) 0.8 0 14.73 3 4 0 0 8 6 6 0 0 3.27 4:2
Gavin Williams (R) 5.84 14-8 3.63 244 57 0 31 139 77 73 27 0 1.08 143:71
Yorman Gomez (R) 1.55 0 10.8 1 4 0 0 5 4 4 1 0 2.7 5:1
Austin Peterson (R) 2 0 0 3 0 0 0 1 0 0 0 0 0.5 3:0
Trenton Denholm (R) 1.55 0-1 13.5 2 2 0 0 7 5 5 1 0 2.7 5:2
Tommy Mace (R) 1 0 6 4 1 0 0 2 2 2 1 0 1 4:1
Ryan Webb (L) 1 1-0 6 4 1 0 0 4 2 2 0 0 1.67 3:2
Zane Petty (R) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 1:0
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Bryan Abreu (R) 0.94 6-4 3.88 79 40 0 0 42 28 26 9 0 1.36 41:28
AJ Blubaugh (R) 1.51 5-3 3.7 92 40 0 0 75 40 38 13 0 1.25 71:63
Enyel De Los Santos (R) 1.08 3-3 4.79 67 20 0 0 69 43 38 11 0 1.25 54:45
Josh Hader (L) 0.98 4-1 0.83 55 11 0 0 17 4 4 1 0 0.65 29:24
Steven Okert (L) 0.99 6-2 2.13 68 14 0 1 45 17 16 7 0 0.87 39:47
Nate Pearson (R) 1.25 1-0 3.6 16 12 0 0 16 10 8 1 0 1.4 17:14
Bennett Sousa (L) 0.85 1-3 5.27 27 16 0 1 30 18 16 4 0 1.68 17:25
Logan VanWey (R) 1.33 1-0 2.25 5 0 0 0 8 3 2 1 0 1 8:4
Hayden Wesneski (R) 5.4 5-2 3.5 41 19 0 10 43 25 21 4 0 1.15 51:26
Miguel Ullola (R) 1.28 0 3.38 10 4 0 2 5 4 4 2 0 0.84 6:9
Cody Bolton (R) 2.5 0-1 5.4 22 14 0 3 21 12 12 3 0 1.75 18:11
Sam Carlson (R) 1.28 0 0 7 1 0 0 4 0 0 0 0 0.94 5:3
Michael Knorr (R) 1.03 0 2.7 3 1 0 0 4 2 1 0 0 1.5 3:5
Peter Lambert (R) 5.59 8-10 3.7 147 57 0 27 128 64 62 15 0 1.23 112:110
Hudson Leach (R) 1 0 0 3 0 0 0 2 0 0 0 0 0.67 2:2
Anthony Maldonado (R) 1.02 1-0 2.84 2 1 0 0 3 2 2 1 0 0.63 6:5
Roddery Munoz (R) 1.33 0 15.75 6 6 0 0 7 7 7 3 0 3.25 2:1
Alimber Santa (R) 1.51 0-1 1.17 9 6 0 0 8 6 2 1 0 0.91 19:10
Amos Willingham (R) 1 0-3 10.5 10 4 0 0 9 9 7 1 0 2.17 9:0
Tom Cosgrove (L) 1.03 1-0 2.35 5 2 0 0 3 2 2 1 0 0.65 6:4
Trey McLoughlin (R) 0.5 0 0 0 0 0 0 0 0 0 0 0 0 1:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Franco Aleman (R) 1.05 0-1 4.43 28 10 0 0 25 12 11 4 0 1.57 10:13
Kolby Allard (L) 2.05 0 10.38 9 3 0 0 16 10 10 2 0 2.19 10:3
Joey Cantillo (L) 4.81 10-9 3.74 167 79 0 30 143 79 64 17 0 1.44 128:86
Matt Festa (R) 1.02 2-3 3.46 69 20 0 0 64 30 25 6 0 1.29 51:33
Hunter Gaddis (R) 0.88 4-3 2.67 54 21 0 0 49 17 17 5 0 1.22 48:39
Erik Sabrowski (L) 0.79 5-2 2.78 70 29 0 0 25 17 14 3 0 1.19 10:29
Connor Brogdon (R) 1 2-2 5.06 15 3 0 0 15 12 9 5 0 1.13 17:12
Colin Holderman (R) 0.97 6-4 2.73 50 20 0 0 35 18 16 1 0 1.04 60:26
Shawn Armstrong (R) 0.87 2-1 4.91 33 19 0 0 29 19 18 4 0 1.45 26:22
Pedro Avila (R) 1.35 0 3.24 4 1 0 0 10 4 3 1 0 1.32 12:4
Tanner Burns (R) 1 0-1 4.5 2 3 0 0 3 2 2 0 0 1.5 5:2
Carlos Hernandez (R) 1.5 0 6 4 1 0 0 5 2 2 1 0 2 2:0
Codi Heuer (R) 1.15 0-1 4.66 6 5 0 0 12 5 5 0 0 1.76 9:10
Jack Leftwich (R) 0.64 0 0 5 0 0 0 0 0 0 0 0 0 3:2
Jake Miller (R) 0.4 0-1 16.2 3 3 0 0 0 3 3 0 0 1.8 1:0
Peyton Pallette (R) 1.26 1-2 5.23 22 16 0 0 17 13 12 2 0 1.6 18:7
Steven Perez (L) 0.67 0 4.5 3 2 0 0 2 1 1 1 0 2 2:1
Trevor Stephan (R) 0.78 0 2.7 5 4 0 0 3 1 1 0 0 2.1 4:1
Jack Carey (R) 0.5 0 0 0 1 0 0 1 0 0 0 0 2 3:0
Jay Driver (R) 0.75 0 3 2 1 0 0 3 1 1 0 0 1.33 2:5
Magnus Ellerts (R) 0.7 0 3.86 4 0 0 0 1 1 1 1 0 0.43 2:1
Matt Jachec (R) 0.55 0 0 2 1 0 0 0 0 0 0 0 0.75 0:0
Jack Jasiak (R) 0.7 0 3.86 4 0 0 0 2 1 1 0 0 0.86 2:1
Izaak Martinez (L) 0.7 0 0 1 1 0 0 1 0 0 0 0 0.86 3:0
Xavier Martinez (R) 0.6 0 0 1 3 0 0 0 0 0 0 0 1.8 1:2
Zane Morehouse (R) 0.6 0 16.2 2 2 0 0 2 3 3 0 0 2.4 1:2
Cam Schuelke (R) 0.55 1-0 0 5 3 0 0 1 0 0 0 0 1.5 1:2
Hunter Stanley (R) 0.55 0 0 1 1 0 0 0 0 0 0 0 0.38 2:2
Tyler Thornton (R) 0.7 0 19.29 5 4 0 0 2 5 5 2 0 2.57 1:1
Adam Tulloch (L) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Alaska Abney (R) 1 0 0 0 1 0 0 1 0 0 0 0 2 2:1
Ross Carver (R) 1 0 0 0 1 0 0 1 0 0 0 0 2 1:0
Sean Matson (R) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Logan McGuire (R) 0.1 0 0 1 0 0 0 1 0 0 0 0 1.5 0:0
Reid Johnston (R) 0.1 0 0 1 0 0 0 0 0 0 0 0 0 0:0
Craig Yoho (R) 1.01 0-1 6.11 22 9 0 0 17 12 12 3 0 1.47 16:4
Umpire G W-L AVG PIT STR B STR% STR_ BB K/BB HR O/U
Alex Tosi 0 0-0 0 0 0 0 0 0 0 0 0 0-0

Line Up - Last Game

Houston Astros
Pitchers
POS Player
SP Cristian Javier
Hitters
POS Player
SS Jeremy Pena
DH Yordan Alvarez
3B Isaac Paredes
2B Jose Altuve
C Yainer Diaz
1B Christian Walker
LF Taylor Trammell
RF Cam Smith
CF Brice Matthews
Cleveland Guardians
Pitchers
POS Player
SP Payton Tolle
RP Alec Gamboa
RP Jovani Moran
RP Erik Miller
Hitters
POS Player
LF Roman Anthony
1B Nick Sogard
DH Jahmai Jones
RF Wilyer Abreu
C Adley Rutschman
3B Caleb Durbin
2B Andruw Monasterio
SS Isiah Kiner-Falefa
CF Nate Eaton
  • HOU
  • CLE
MLB Odds