Sports Interaction
Promotions
Sports Interaction
Promotions

Houston Astros vs. Cleveland Guardians Odds, Stats April 22, 2026

Final Score
American League West
Apr 22nd, 1:10 PM EDT
Houston
Astros
Cleveland
Guardians
2
0
Houston Astros
Cleveland Guardians
Scoreboard 1 2 3 4 5 6 7 8 9 R ML H E
Houston Astros 81-81 2 0 0 0 0 0 0 0 - 2 +135 6 1
Cleveland Guardians 85-77 0 0 0 0 0 0 0 0 - 0 -160 5 0
Loading odds...

Latest Encounters

Date Result Competition Stats Recap
10/19/26
Cleveland Guardians CLE ( 85-77 )
Tampa Bay Rays TB ( 98-64 )
3   -   7
 American League Central
10/18/26
Tampa Bay Rays TB ( 98-64 )
Cleveland Guardians CLE ( 85-77 )
3   -   1
 American League East
10/17/26
Tampa Bay Rays TB ( 98-64 )
Cleveland Guardians CLE ( 85-77 )
7   -   3
 American League East

Matchup Odds

Team Runline Moneyline Over / Under
Houston Astros HOU
+1.5 0 0 U+8.50
Cleveland Guardians CLE
-1.5 0 0 O+8.50

Line History

time fav spread money line total
Opening 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110
Closing 22 Apr 5:31pm HOU -1.5 +155 -190 O +8 -110

Line History

Team Leaders

Houston Astros HOU
Cleveland Guardians CLE
Yordan Alvarez
Designated Hitter Cleveland
42 HR 18
Angel Martinez
Left Outfield Houston
Chase DeLauter
Right Outfield Houston
0.3 BA 0.3
Yordan Alvarez
Designated Hitter Cleveland
Jose Ramirez
Third Base Houston
37 SB 12
Jeremy Pena
Shortstop Cleveland
Houston Astros HOU
Cleveland Guardians CLE
Jose Ramirez
Third Base Houston
2 HR 1
Jose Altuve
Second Base Cleveland
Angel Genao
Second Base Houston
0.5 BA 0.4
Jeremy Pena
Shortstop Cleveland
Jose Ramirez
Third Base Houston
3 SB 0
Bryan Abreu
Reliever Cleveland

Matchup Details

Houston Astros HOU
Cleveland Guardians CLE
Stat
9 Wins 14
16 Losses 11
5-5 Last 10 8-2
-11.77 Units 5.17
7-6 Wins Home 8-4
2-10 Wins Away 6-7
18-7 Covers Against Ou 13-12
9-16 Run Line Wins Losses 15-10
-7.75 Runline Units 4.15

Odds Analysis

Team Rankings

Houston Astros HOU
Season stats rank
ERA 4.46 7
WHIP 1.34 10
KS 1343 16
CG - -
Errors 73 10
Cleveland Guardians CLE
Season stats rank
ERA 3.76 23
WHIP 1.26 23
KS 1271 26
CG - -
Errors 85 17
Houston Astros HOU
Season stats rank
Runs / G 4.53 13
BA 0.24 18
OPS 0.73 10
HR 226 1
SB 50 30
Cleveland Guardians CLE
Season stats rank
Runs / G 4.19 24
BA 0.24 24
OPS 0.7 25
HR 162 27
SB 146 7

Injuries

Houston Astros HOU
Cleveland Guardians CLE

Houston vs. Cleveland Betting News

Houston Vs Cleveland Betting Trends

Houston Astros HOU

Over is 5-1 in Astros last 6 games vs. a right-handed starter.

Under is 5-1 in Astros last 6 Wednesday games.

Over is 7-0 in Astros last 7 games with the total set at 9.0-10.5.

Astros are 19-7 in their last 26 games with the total set at 11.0 or higher.

Over is 10-4 in Astros last 14 games as a favorite.

Cleveland Guardians CLE

Under is 6-1-3 in Guardians last 10 Wednesday games.

Under is 3-1-2 in Guardians last 6 games with the total set at 9.0-10.5.

Guardians are 5-2 in their last 7 games with the total set at 11.0 or higher.

Over is 4-1 in Guardians last 5 games as a favorite.

Guardians are 3-7 in their last 10 when their opponent allows 5 runs or more in their previous game.

Pitchers & Umpires

Today - Overall

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (R) - - - - - - 81-81 - - - - -
Tanner Bibee (R) - - - - - - 85-77 - - - - -

Today - Last 3

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Peter Lambert (R) - - - - - - 81-81 - - - - -
Tanner Bibee (R) - - - - - - 85-77 - - - - -
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Jason Alexander (R) 4.53 1-1 9.33 14 8 0 2 21 19 19 4 0 1.58 21:10
Spencer Arrighetti (R) 5.18 7-5 4.6 87 50 0 17 68 47 45 12 0 1.34 69:53
Ronel Blanco (R) 4.15 0-1 6.68 29 16 0 5 30 25 25 9 0 1.37 27:26
Hunter Brown (R) 5.14 6-5 43.69 126 56 0 21 86 46 41 11 0 10.27 118:42
J.P. France (R) 2.07 0 8.1 4 5 0 0 6 6 6 1 0 1.65 8:6
Colton Gordon (L) 2.28 0 11.57 11 3 0 1 21 12 12 6 0 2.57 7:3
Cristian Javier (R) 3.71 2-6 5.14 59 28 0 12 64 36 36 10 0 1.46 32:61
Bryan King (L) 1 3-6 59.19 52 23 0 1 73 41 37 9 0 13.52 74:24
Lance McCullers Jr. (R) 4.89 2-3 6.86 43 22 0 8 38 32 30 7 0 1.53 32:18
Jayden Murray (R) 1.64 0 7.43 8 7 0 0 19 11 11 1 0 1.95 9:14
Ryan Weiss (R) 2.89 0-3 7.62 30 20 0 2 35 24 22 8 0 2.12 18:12
Mike Burrows (R) 5.23 4-9 5.99 75 35 0 17 112 69 63 21 0 1.55 85:60
Tatsuya Imai (R) 3.31 6-4 4.93 97 51 0 15 58 42 42 9 0 1.42 60:38
Kai-Wei Teng (R) 2.44 5-7 4.76 73 33 0 10 69 43 39 10 0 1.38 64:37
Ethan Pecko (R) 4.26 2-0 3.93 23 14 0 5 25 16 15 5 0 1.14 28:24
Amilcar Chirinos (R) 0.2 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Wilmy Sanchez (R) 2 0 0 3 0 0 0 0 0 0 0 0 0 2:1
Trey Dombroski (L) 1.05 0-1 11.57 1 0 0 0 3 3 3 2 0 1.29 1:3
Joey Mancini (R) 2 0 0 1 2 0 0 0 0 0 0 0 1 2:0
Alex Santos II (R) 0.1 0 0 0 0 0 0 1 0 0 0 0 3 0:1
Nolan DeVos (R) 2 0 0 1 0 0 0 1 0 0 0 0 0.5 4:1
Dylan Howard (R) 2 0 0 2 1 0 0 2 0 0 0 0 1.5 2:1
Josh Hendrickson (L) 1.37 0 8.78 3 1 0 0 5 2 2 0 0 3.15 4:2
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Logan Allen (L) 2.31 0 5.94 16 6 0 2 23 14 11 3 0 1.74 18:14
Tanner Bibee (R) 5.53 7-15 58.36 149 57 0 33 175 97 93 29 0 7.22 160:120
Slade Cecconi (R) 4.1 5-7 9.41 103 39 0 21 136 74 67 19 0 2.43 126:79
Daniel Espino (R) 1.01 0-1 7.71 33 11 0 4 16 9 9 3 0 2.84 14:9
Tim Herrin (L) 0.84 3-4 8.08 59 30 0 0 52 25 22 5 0 2.81 54:35
Doug Nikhazy (L) 0.8 0 14.73 3 4 0 0 8 6 6 0 0 3.27 4:2
Gavin Williams (R) 5.58 16-8 5.92 281 67 0 35 152 85 81 28 0 1.95 155:75
Yorman Gomez (R) 1.55 0 10.8 1 4 0 0 5 4 4 1 0 2.7 5:1
Austin Peterson (R) 3.5 0-1 2.57 8 2 0 0 4 2 2 2 0 0.86 8:4
Trenton Denholm (R) 1.55 0-1 13.5 2 2 0 0 7 5 5 1 0 2.7 5:2
Tommy Mace (R) 1 0 6 4 1 0 0 2 2 2 1 0 1 4:1
Ryan Webb (L) 1 1-0 6 4 1 0 0 4 2 2 0 0 1.67 3:2
Zane Petty (R) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 1:0
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Bryan Abreu (R) 0.97 6-4 6.19 87 42 0 0 45 29 27 10 0 1.9 44:30
AJ Blubaugh (R) 1.48 5-4 3.66 96 45 0 1 76 42 39 13 0 2.73 74:72
Enyel De Los Santos (R) 1.08 3-3 4.79 67 20 0 0 69 43 38 11 0 1.25 54:45
Josh Hader (L) 1 4-2 1.01 57 15 0 0 22 6 5 1 0 2.05 32:29
Steven Okert (L) 0.99 6-2 2.13 68 14 0 1 45 17 16 7 0 0.87 39:47
Nate Pearson (R) 1.25 1-0 3.6 16 12 0 0 16 10 8 1 0 1.4 17:14
Bennett Sousa (L) 0.86 1-3 15 33 18 0 1 38 23 21 5 0 3.8 19:27
Logan VanWey (R) 1.18 1-0 1.42 9 1 0 0 11 3 2 1 0 0.95 10:9
Hayden Wesneski (R) 5.55 6-2 3.25 46 20 0 11 49 27 22 4 0 1.13 61:27
Miguel Ullola (R) 1.6 2-0 5.16 20 5 0 2 8 5 5 3 0 1.05 11:15
Cody Bolton (R) 2.5 0-1 5.4 22 14 0 3 21 12 12 3 0 1.75 18:11
Sam Carlson (R) 1.28 0 0 7 1 0 0 4 0 0 0 0 0.94 5:3
Michael Knorr (R) 1.03 0 2.7 3 1 0 0 4 2 1 0 0 1.5 3:5
Peter Lambert (R) 5.27 8-10 9.82 156 61 0 29 136 70 68 17 0 1.92 119:113
Hudson Leach (R) 1 0 0 3 0 0 0 2 0 0 0 0 0.67 2:2
Anthony Maldonado (R) 1.02 1-0 2.84 2 1 0 0 3 2 2 1 0 0.63 6:5
Roddery Munoz (R) 1.33 0 15.75 6 6 0 0 7 7 7 3 0 3.25 2:1
Alimber Santa (R) 1.51 0-1 1.17 9 6 0 0 8 6 2 1 0 0.91 19:10
Amos Willingham (R) 1 0-3 10.5 10 4 0 0 9 9 7 1 0 2.17 9:0
Tom Cosgrove (L) 1.03 1-0 2.35 5 2 0 0 3 2 2 1 0 0.65 6:4
Trey McLoughlin (R) 0.5 0 0 0 0 0 0 0 0 0 0 0 0 1:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Franco Aleman (R) 1.05 0-1 4.43 28 10 0 0 25 12 11 4 0 1.57 10:13
Kolby Allard (L) 2.05 0 10.38 9 3 0 0 16 10 10 2 0 2.19 10:3
Joey Cantillo (L) 4.43 11-9 7.22 173 87 0 30 149 81 66 17 0 3.42 138:90
Matt Festa (R) 1 2-3 14.45 70 22 0 0 68 34 29 8 0 3.11 55:36
Hunter Gaddis (R) 0.9 7-3 5.06 65 24 0 0 64 22 22 8 0 2.55 55:47
Erik Sabrowski (L) 0.83 6-3 6.93 85 33 0 0 32 21 18 4 0 2.14 17:35
Connor Brogdon (R) 1 2-2 5.06 15 3 0 0 15 12 9 5 0 1.13 17:12
Colin Holderman (R) 0.97 6-4 2.73 50 20 0 0 35 18 16 1 0 1.04 60:26
Shawn Armstrong (R) 0.92 2-2 5.62 40 19 0 2 33 20 19 4 0 1.73 35:28
Pedro Avila (R) 1.35 0 3.24 4 1 0 0 10 4 3 1 0 1.32 12:4
Tanner Burns (R) 1 0-1 4.5 2 3 0 0 3 2 2 0 0 1.5 5:2
Carlos Hernandez (R) 1.5 0 6 4 1 0 0 5 2 2 1 0 2 2:0
Codi Heuer (R) 1.15 0-1 4.66 6 5 0 0 12 5 5 0 0 1.76 9:10
Jack Leftwich (R) 0.64 0 0 5 0 0 0 0 0 0 0 0 0 3:2
Jake Miller (R) 0.4 0-1 16.2 3 3 0 0 0 3 3 0 0 1.8 1:0
Peyton Pallette (R) 1.26 1-2 5.23 22 16 0 0 17 13 12 2 0 1.6 18:7
Steven Perez (L) 0.67 0 4.5 3 2 0 0 2 1 1 1 0 2 2:1
Trevor Stephan (R) 0.78 0 2.7 5 4 0 0 3 1 1 0 0 2.1 4:1
Jack Carey (R) 0.5 0 0 0 1 0 0 1 0 0 0 0 2 3:0
Jay Driver (R) 0.75 0 3 2 1 0 0 3 1 1 0 0 1.33 2:5
Magnus Ellerts (R) 0.7 0 3.86 4 0 0 0 1 1 1 1 0 0.43 2:1
Matt Jachec (R) 0.55 0 0 2 1 0 0 0 0 0 0 0 0.75 0:0
Jack Jasiak (R) 0.7 0 3.86 4 0 0 0 2 1 1 0 0 0.86 2:1
Izaak Martinez (L) 0.7 0 0 1 1 0 0 1 0 0 0 0 0.86 3:0
Xavier Martinez (R) 0.6 0 0 1 3 0 0 0 0 0 0 0 1.8 1:2
Zane Morehouse (R) 0.6 0 16.2 2 2 0 0 2 3 3 0 0 2.4 1:2
Cam Schuelke (R) 0.55 1-0 0 5 3 0 0 1 0 0 0 0 1.5 1:2
Hunter Stanley (R) 0.55 0 0 1 1 0 0 0 0 0 0 0 0.38 2:2
Tyler Thornton (R) 0.7 0 19.29 5 4 0 0 2 5 5 2 0 2.57 1:1
Adam Tulloch (L) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Alaska Abney (R) 1 0 0 0 1 0 0 1 0 0 0 0 2 2:1
Ross Carver (R) 1 0 0 0 1 0 0 1 0 0 0 0 2 1:0
Sean Matson (R) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Logan McGuire (R) 0.1 0 0 1 0 0 0 1 0 0 0 0 1.5 0:0
Reid Johnston (R) 0.1 0 0 1 0 0 0 0 0 0 0 0 0 0:0
Craig Yoho (R) 0.95 0-1 6.87 23 10 0 0 20 14 14 3 0 1.64 17:4
Umpire G W-L AVG PIT STR B STR% STR_ BB K/BB HR O/U
Alex Tosi 0 0-0 0 0 0 0 0 0 0 0 0 0-0

Line Up - Last Game

Houston Astros
Pitchers
POS Player
SP Sean Burke
RP Huascar Brazoban
RP Anthony Kay
RP Jordan Hicks
RP Erick Fedde
Hitters
POS Player
LF Sam Antonacci
C Kyle Teel
3B Miguel Vargas
1B Munetaka Murakami
DH Andrew Benintendi
CF Tristan Peters
2B Chase Meidroth
RF Braden Montgomery
SS Colson Montgomery
Cleveland Guardians
Pitchers
POS Player
SP Freddy Peralta
RP Cam Booser
RP Tyler Wells
RP Ian Seymour
RP Kevin Kelly
RP Bryan Baker
Hitters
POS Player
DH Yandy Diaz
1B Jonathan Aranda
C Liam Hicks
3B Junior Caminero
LF Chandler Simpson
RF Victor Mesa Jr.
CF Jonny DeLuca
2B Richie Palacios
SS Taylor Walls
  • HOU
  • CLE
MLB Odds