Two teams that have combined to win the past four AFC South titles meet on Sunday morning from London when the disappointing Houston Texans take on the current division-leading Jaguars. Jacksonville is -2.5 on the NFL odds with a total of 42.5.

Texans vs. Jaguars Kickoff, Weather, TV, Streaming Info

All these London games kick off at 9:30 a.m. ET, and this is shown exclusively in the United States on Sunday via the NFL Network and DAZN. Wembley Stadium has a roof over all the seating but not the field. The forecast for Sunday in London: Partly to mostly cloudy. High 58F. Winds NNE at 10 to 20 mph.

NFL Betting Odds, Point Spread, Trends

This is the third straight week the NFL is staging a game in London but first at Wembley Stadium and that will be it for England in 2026. If Jacksonville wins this game, I don’t want to say the AFC South race is already finished in Week 6, but it might be short of the Jaguars losing starting QB Trevor Lawrence to serious injury. Jacksonville is 4-1 and the other three clubs in that division are a combined 3-12. Thus, the Jags are heavy -480 favourites to repeat.

No one expected much from Indianapolis or anything from Tennessee, but Houston at 1-4 after winning at least 10 games each of the past three seasons and reaching the Divisional Round of the AFC playoffs in each is a big surprise. But the team managed to accomplish that in 2025 after staring 0-3. Houston is +650 in the division and can all but forget about it with this head-to-head loss. The clubs play again Week 15 in Houston.

Last season, they split with each winning by a touchdown at home – Jacksonville is officially the home squad in London. That Jags loss was what dropped Houston to 0-3. It was the Jags’ first home win against the Texans since 2017. Houston is 7-3 SU in the past 10 overall and the over-under 4-6.

NFL Player Odds and Props

In a surprise, Parker Washington has become Trevor Lawrence’s top receiving target on Jacksonville, and I like Washington for his fifth TD catch already. The same prop on Houston running back Woody Marks, especially if fellow running back David Montgomery is out injured – he might be.

Houston Texans

It was a productive Sunday for Houston as not only did it temporarily save its season with a 26-3 win at awful Tennessee for that first W but also acquired former Ohio State All-American wideout Marvin Harrison Jr. in a trade with Arizona. Harrison was the No. 4 overall pick in the 2024 draft but had been a bust and fallen out of favour with the Cardinals. Now he’s reunited with his college quarterback in C.J. Stroud. While his team is 1-4, Stroud is having a nice season – passing and rushing score vs. the Titans — and still hasn’t been picked off. His 185 attempts without an interception are the fourth-most through five games in league history. No. 1 running back David Montgomery and cornerback Jalen Pitre left Sunday injured.

Jacksonville Jaguars

Jacksonville hosted Philadelphia at Tottenham Hotspur this past Sunday in London – the team will simply stay overseas – and stole a victory, 19-17. Simply put, Eagles coach Nick Sirianni made an utterly boneheaded decision to kick off in full after Philly had scored for a 17-16 lead with eight seconds left. The Jags returned that kickoff 57 yards with one second still on the clock to set up Cam Little’s walk-off 57-yard field goal. It was only the second game in the Super Bowl era in which both teams made a field goal in the final 10 seconds of regulation but second this season (Ravens-Cowboys). Trevor Lawrence threw for 331 yards and two scores. It was his third career international game with at least 300 passing yards to tie for the all-time league record. Offensive tackle Anton Harrison and cornerback Montaric Brown both left injured.

Texans vs. Jaguars Week 6 Score Prediction:

TEXANS

Away

20

JAGUARS

Home

23

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Predictions

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