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Texans vs. Colts Prediction, Odds & Stats September 27, 2026

Final Score
AFC South
Sep 27th, 1:00 PM EDT
Houston
Texans
Indianapolis
Colts
17
19
Houston Texans
Indianapolis Colts
Scoreboard 1 2 3 4 Odds
Houston Texans 2-5 0 7 0 10 +45
Indianapolis Colts 2-6 3 10 0 6 +2.5
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Latest Encounters

Date Result Competition Stats Recap
11/01/26
Indianapolis Colts IND ( 2-6 )
Jacksonville Jaguars JAC ( 5-2 )
7   -   42
 AFC South
10/25/26
N.Y. Giants Giants NYG ( 4-2 )
Houston Texans HOU ( 2-5 )
27   -   21
 NFC East
10/25/26
Indianapolis Colts IND ( 2-6 )
Minnesota Vikings MIN ( 6-1 )
10   -   16
 AFC South

Line History

Matchup Details

Houston Texans HOU
Indianapolis Colts IND
Stat
0 Games Won 0
2 Games Lost 2
2-5 Last 10 2-6
0-0 W L Streak 0-0
0-2 Against The Spread 1-1
0 Money 0
0-0 Home 0-0
0-0 Away 0-0
1-1 Total 2-0

Recent Meetings

date home-away ats o/u IND:Total Net Yards IND:Net Rushing Yards IND:Passing Yards HOU:Total Net Yards HOU:Net Rushing Yards HOU:Passing Yards
09/27/2026 IND 19 - HOU 17 IND +2.5 Under 45 300 89 211 223 70 153
01/04/2026 HOU 38 - IND 30 IND +9.5 Over 37.5 354 76 278 339 134 205
11/30/2025 IND 16 - HOU 20 HOU +3.5 Under 44.5 364 108 256 281 86 195
10/27/2024 HOU 23 - IND 20 IND +4.5 Under 45.5 303 163 140 363 96 267
09/08/2024 IND 27 - HOU 29 IND +1.5 Over 48.5 417 213 204 303 104 199
01/06/2024 IND 19 - HOU 23 HOU +1 Under 47 306 60 246 360 227 133
09/17/2023 HOU 20 - IND 31 IND +2 Over 40.5 353 126 227 389 52 337
01/08/2023 IND 31 - HOU 32 HOU +3 Over 37.5 360 59 301 398 196 202
09/11/2022 HOU 20 - IND 20 HOU +8 Under 45.5 517 177 340 299 77 222
12/05/2021 HOU 0 - IND 31 IND -10 Under 46 389 238 151 141 84 57
10/17/2021 IND 31 - HOU 3 IND -9.5 Under 45.5 353 124 229 388 174 214
12/20/2020 IND 27 - HOU 20 IND -7.5 Under 52.5 425 83 342 350 127 223
12/06/2020 HOU 20 - IND 26 IND -2.5 Under 50 371 109 262 398 90 308
11/21/2019 HOU 20 - IND 17 HOU -4 Under 46 296 175 121 396 99 297
10/20/2019 IND 30 - HOU 23 IND -1.5 Over 46.5 391 100 291 383 62 321
01/05/2019 HOU 7 - IND 21 IND +2 Under 48 422 200 222 322 105 217
12/09/2018 HOU 21 - IND 24 IND +4 Under 49 436 50 386 315 89 226
09/30/2018 IND 34 - HOU 37 HOU +2 Over 48 466 119 347 478 41 437
12/31/2017 IND 22 - HOU 13 IND -5.5 Under 43 209 85 124 250 146 104
11/05/2017 HOU 14 - IND 20 IND +6 Under 48 371 92 279 288 94 194
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
10/25/2026 HOU 21 - NYG 27 L -8.5 Over 42.5 420 188 232
10/18/2026 JAC 31 - HOU 34 W +1.5 Over 42 426 114 312
10/11/2026 TEN 3 - HOU 26 W -7 Under 39.5 329 79 250
10/04/2026 HOU 30 - DAL 34 L -2.5 Over 48.5 399 75 324
09/27/2026 IND 19 - HOU 17 L -2.5 Under 45 223 70 153
09/20/2026 HOU 6 - CIN 20 L -2 Under 46.5 267 85 182
09/13/2026 HOU 31 - BUF 36 L +1.5 Over 44.5 409 86 323
08/28/2026 CAR 16 - HOU 13 L -1 Under 36.5 173 81 92
08/20/2026 HOU 20 - LV 22 L +1 Over 38.5 400 159 241
08/13/2026 HOU 7 - LAC 27 L -1.5 Under 38 379 104 275
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
11/01/2026 JAC 42 - IND 7 L +10 Over 46.5 366 183 183
10/25/2026 MIN 16 - IND 10 W +6 Under 42.5 275 136 139
10/18/2026 IND 20 - TEN 26 L -6.5 Over 43.5 399 165 234
10/11/2026 PIT 34 - IND 22 L +2.5 Over 42 352 127 225
10/04/2026 WAS 13 - IND 30 W +1.5 Under 49.5 317 100 217
09/27/2026 IND 19 - HOU 17 W +2.5 Under 45 300 89 211
09/20/2026 KC 33 - IND 30 L +6.5 Over 47 523 152 371
09/13/2026 IND 23 - BAL 41 L +4 Over 49.5 251 102 149
08/29/2026 IND 16 - DET 25 L -1 Over 36.5 229 34 195
08/22/2026 IND 6 - ATL 34 L -1 Over 37.5 164 85 79

Odds Analysis

Team Rankings

Houston Texans HOU
Season stats rank
Total Yards 342 19
Passing Yards 244 28
Rushing Yards 98 11
Points Scored 24.29 18
Field Goal % 0.76 9
Indianapolis Colts IND
Season stats rank
Total Yards 343.5 22
Passing Yards 211.75 12
Rushing Yards 131.75 27
Points Scored 27.75 30
Field Goal % 0.9 24
Houston Texans HOU
Season stats rank
Total Yards 338.1 16
Passing Yards 253.43 7
Rushing Yards 84.71 29
Points Scored 23.57 13
Field Goal % 0.94 5
Indianapolis Colts IND
Season stats rank
Total Yards 291.1 26
Passing Yards 174.63 28
Rushing Yards 116.5 16
Points Scored 20.13 26
Field Goal % 0.9 11

Injuries

Houston Texans HOU
Indianapolis Colts IND

Houston vs. Indianapolis Betting News

Houston Vs Indianapolis Betting Trends

Houston Texans HOU

Under is 9-4 in Texans last 13 games as a favorite.

Texans are 5-2-1 ATS vs. a team with a losing record.

Texans are 4-1 ATS in their last 5 road games.

Under is 4-0-2 in Texans last 6 games after scoring less than 15 points in their previous game.

Under is 8-1 in Texans last 9 games in September.

Indianapolis Colts IND

Over is 5-2 in Colts last 7 games as a home underdog of 3.5-10.0.

Colts are 0-5 ATS in their last 5 home games.

Colts are 4-0 ATS in their last 4 games as a home underdog of 0.5-3.0.

Over is 19-7 in Colts last 26 vs. a team with a losing record.

Over is 9-3 in Colts last 12 games as a favorite.

AFC South Standings

Line Up - Last Game

Houston Texans
Pitchers
POS Player
Hitters
POS Player
Indianapolis Colts
Pitchers
POS Player
Hitters
POS Player
  • HOU
  • -2.5 +2.5
  • IND
NFL Odds