Bills vs. 49ers Odds NFL Odds

December 7, 2020, 08:15 PM ET
State Farm Stadium

Matchup Odds

Sports Interaction customers are placing their bets on:

Team Spread Moneyline Over / Under
BUF +1 -115 -108 U+48.5-105
SF -1 -105 -112 O+48.5-115

Betting Action

Sports Interaction customers are placing their bets on:

team
BUF

78%

SF

22%

Over/Under
Over

73%

Under

27%

Line History

Sports Interaction customers are placing their bets on:

time fav line total
Opening 26 Nov 5:16am BUF -2.5 -115 O +48.5 -110
Closing 7 Dec 11:51pm BUF -1.5 -101 O +48 -115
Line History
Spread
Total
  • Regular Season
  • Playoffs

Team Leaders

BUF SF
Touchdowns

Stefon Diggs

8

Jeff Wilson Jr.

10

Rushing

Devin Singletary

687

Jeff Wilson Jr.

600

Passing

Josh Allen

4544

Nick Mullens

2437

Receiving

Stefon Diggs

127

Brandon Aiyuk

60

Sacks

A.J. Klein

5

Kerry Hyder Jr.

8.5

Interceptions

Tre'Davious White

3

Fred Warner

2

BUF SF
Touchdowns

Stefon Diggs

2

Rushing

Josh Allen

57

Passing

Josh Allen

530

Did not qualify
Receiving

Stefon Diggs

14

Sacks

Jerry Hughes

2

Interceptions

Taron Johnson

1

  • Regular Season
  • Playoffs

Team Leaders

Touchdowns

Stefon Diggs

8

Rushing

Devin Singletary

687

Passing

Josh Allen

4544

Receiving

Stefon Diggs

127

Sacks

A.J. Klein

5

Interceptions

Tre'Davious White

3

Touchdowns

Jeff Wilson Jr.

10

Rushing

Jeff Wilson Jr.

600

Passing

Nick Mullens

2437

Receiving

Brandon Aiyuk

60

Sacks

Kerry Hyder Jr.

8.5

Interceptions

Fred Warner

2

Touchdowns

Stefon Diggs

2

Rushing

Josh Allen

57

Passing

Josh Allen

530

Receiving

Stefon Diggs

14

Sacks

Jerry Hughes

2

Interceptions

Taron Johnson

1

Touchdowns
Rushing
Passing Did not qualify
Receiving
Sacks
Interceptions

Matchup Details

team win loss last 10 w/l streak ats money home away total
Orchard Park 8 3 9-1 6W 6-5 0 0-0 0-0 7-3-1
San Francisco 5 6 3-7 1L 5-6 0 0-0 0-0 5-6
  • Recent Meetings
  • BUF Last 10
  • SF Last 10

Recent Meetings

date home-away ats o/u SF:Total Net Yards SF:Net Rushing Yards SF:Passing Yards BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards
12/07/2020 SF 24 - BUF 34 BUF -3 Over 48 402 86 316 449 81 368
10/16/2016 BUF 45 - SF 16 BUF -7.5 Over 44 492 313 179 300 133 167
10/07/2012 SF 45 - BUF 3 SF -10 Over 45.5 621 311 310 204 89 115

Buffalo Last 10 Meetings

date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
01/16/2021 BUF 17 - BAL 3 W -3 Under 49.5 340 150 190
01/09/2021 BUF 27 - IND 24 L -6.5 Under 51.5 472 163 309
01/03/2021 BUF 56 - MIA 26 W -4.5 Over 43 454 70 384
12/28/2020 NE 9 - BUF 38 W -6.5 Under 47.5 474 130 344
12/19/2020 DEN 19 - BUF 48 W -6 Over 48 534 182 352
12/13/2020 BUF 26 - PIT 15 W Under 48.5 224 47 177
12/07/2020 SF 24 - BUF 34 W -3 Over 48 449 81 368
11/29/2020 BUF 27 - LAC 17 W -4.5 Under 51.5 367 76 291
11/15/2020 ARI 32 - BUF 30 W +3 Over 56 369 73 296
11/08/2020 BUF 44 - SEA 34 W +2.5 Over 55.5 419 57 362

San Francisco Last 10 Meetings

date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
01/03/2021 SF 23 - SEA 26 W +7 Over 44.5 328 86 242
12/26/2020 ARI 12 - SF 20 W +4 Under 49 350 120 230
12/20/2020 DAL 41 - SF 33 L -1 Over 45 291 87 204
12/13/2020 SF 15 - WAS 23 L -3 Under 43.5 344 108 236
12/07/2020 SF 24 - BUF 34 L +3 Over 48 402 86 316
11/29/2020 LAR 20 - SF 23 W +5 Under 45 308 126 182
11/15/2020 NO 27 - SF 13 L +9.5 Under 50 237 114 123
11/05/2020 SF 17 - GB 34 L +6 Under 52 337 55 282
11/01/2020 SEA 37 - SF 27 L +4 Over 54.5 350 101 249
10/25/2020 NE 6 - SF 33 W +3 Under 45.5 241 94 147

Matchup Edge - Scoring Stats

avg rank edge in rank avg
22 7 Points Per Game 1
13.5 1 Points Allowed Per Game 1
5 5 1st Quarter Scoring Per Game 1
1.5 1 1st Quarter Scoring Allowed Per Game 1
3.5 8 2nd Quarter Scoring Per Game 1
5 1 2nd Quarter Scoring Allowed Per Game 1
8.5 3 3rd Quarter Scording Per Game 1
1 3rd Quarter Scoring Allowed Per Game 1
5 6 4th Quarter Scoring Per Game 1
7 4 4th Quarter Scoring Allowed Per Game 1
75.0 2 Red Zone Efficiency 1
308.5 10 Total Yards Per Game 1
8.57 10 Total Yards Per Play 1
3.46 11 Rushing Yards Per Play 1
36 7 Passing Attempts Per Game 1
9.98 10 Passing Yards Per Completion 1
1.5 3 Passing Tds Per Game 1
24.5 4 Completions Per Game 1
68.1 4 Completion % 1
103.36 2 Qb Rating 15 2.1
2 4 Defense Sacks Per Game 1
1 Defense Interceptions Per Game 1
3 4 Opponent Fumbles Per Game 1
1 Opponent Fumbles Lost Per Game 1
2 1 Penalties Per Game 1
9 1 Penalty Yards Per Game 1
1 Takeaway / Giveaway Differential 1
1 9 Yards Per Punt Return 1
19 10 Yards Per Kickoff Return 1

Odds Analysis

Overall W/L Records

Team Overall Home Away Grass Turf Div Conf
Bills 15-3 9-1 5-2 4-2 11-1 6-0 12-2
49ers 6-9 1-4 5-3 2-6 4-3 3-2 4-7

ATS vs Closing Line

Team Overall Home Away Grass Turf Div Conf
Bills 12-6 7-3 4-3 4-2 8-4 3-3 8-6
49ers 6-9 1-4 5-3 2-6 4-3 3-2 4-7

O/U Records

Team Overall home away grass turf div conf
Bills 11-6-1 6-4 4-2-1 5-0-1 6-6 4-2 7-6-1
49ers 7-8 2-3 4-4 3-5 4-3 1-4 4-7

Team Rankings - offence

Season stats rank
Total Yards 396.4 3
Passing Yards 288.75 3
Rushing Yards 107.69 20
Points Scored 31.31 2
Field Goal % 0.82 18
Season stats rank
Total Yards 370.1 15
Passing Yards 252.06 12
Rushing Yards 118.06 15
Points Scored 23.5 21
Field Goal % 0.85 15

Team Rankings - defence

Season stats rank
Total Yards 352.5 14
Passing Yards 232.88 13
Rushing Yards 119.63 17
Points Scored 23.44 16
Field Goal % 0.92 30
Season stats rank
Total Yards 314.4 5
Passing Yards 207.94 4
Rushing Yards 106.44 7
Points Scored 24.38 17
Field Goal % 0.89 27

Weather

condition dome

Buffalo News + Tweets

San Francisco News + Tweets

Injuries

Prob Sun Knee - 21 / 01 / 21
Prob Sun Ankle - 20 / 01 / 21
Ques Sun Quadricep - 20 / 01 / 21
Ques Sun Ankle - 16 / 01 / 21
Prob Sat Knee - 12 / 01 / 21
Prob Sun Knee - 12 / 01 / 21
Prob Sat Ankle - 12 / 01 / 21
Prob Sat Groin - 12 / 01 / 21
I-R Ankle - 09 / 01 / 21
Prob Sat Ankle - 05 / 01 / 21
Out Sun Undisclosed - 01 / 01 / 21
Out Sun Calf - 01 / 01 / 21
Ques Sun Hamstring - 31 / 12 / 20
Ques Sun Knee - 31 / 12 / 20
out for season Ankle - 31 / 12 / 20
Out indefinitely Illness - 30 / 12 / 20
Ques Sun Illness - 30 / 12 / 20
Out Sun Shin - 30 / 12 / 20
Ques Sun Ankle - 28 / 12 / 20
Out Sun Ankle - 28 / 12 / 20

Injuries

player (position) status ats*current o/u* notes
Cole Beasley (WR) Prob Sun Knee - 21 / 01 / 21 1-0 0-1 + -

Beasley is tending to a knee injury, but it is likely that he will suit up for the AFC Championship game versus the Chiefs.

Quinton Jefferson (DL) Prob Sun Ankle - 20 / 01 / 21 1-0 0-1 + -

Jefferson has an injured ankle, but it is anticipated that he will line up against the Chiefs in the AFC Championship game.

Vernon Butler (DT) Ques Sun Quadricep - 20 / 01 / 21 1-0 0-1 + -

Butler is bothered by a quad injury, and it has yet to be established if he will take part in the AFC Championship game versus the Chiefs.

Gabriel Davis (WR) Ques Sun Ankle - 16 / 01 / 21 1-1 1-1 + -

Davis is nursing an ankle injury, and his status for the AFC Championship game versus the Chiefs is in question.

Cole Beasley (WR) Prob Sat Knee - 12 / 01 / 21 1-1 1-1 + -

Beasley is nursing a knee injury, but it is anticipated that he will be available for the AFC divisional round versus the Ravens.

Darryl Johnson (DE) Prob Sun Knee - 12 / 01 / 21 1-1 1-1 + -

Johnson is dealing with a knee injury, but it is anticipated that he will partake in the AFC Championship game against the Chiefs.

Ed Oliver (DT) Prob Sat Ankle - 12 / 01 / 21 1-1 1-1 + -

Oliver is tending to an ankle injury, but it is anticipated that he will be active for the AFC divisional round versus the Ravens.

Justin Zimmer (DT) Prob Sat Groin - 12 / 01 / 21 1-1 1-1 + -

Zimmer is bothered by a groin injury, but it is likely that he will line up against the Ravens in the AFC divisional round.

Zack Moss (RB) I-R Ankle - 09 / 01 / 21 2-1 2-1 + -

Moss has been posted to the injured reserve list due to an ankle injury.

Isaiah McKenzie (WR) Prob Sat Ankle - 05 / 01 / 21 2-1 2-1 + -

McKenzie is tending to an ankle injury, but it is expected that he will line up against the Colts in the AFC Wild Card game.

player (position) status ats*current o/u* notes
Kevin Givens (DL) Out Sun Undisclosed - 01 / 01 / 21 1-0 0-1 + -

Givens will be unavailable for Sunday's clash against the Seahawks for unlisted reasons.

Dre Greenlaw (LB) Out Sun Calf - 01 / 01 / 21 1-0 0-1 + -

Greenlaw has a calf injury, and it will keep him on the sidelines versus the Seahawks on Sunday.

Emmanuel Moseley (CB) Ques Sun Hamstring - 31 / 12 / 20 1-0 0-1 + -

Moseley is battling a hamstring issue, and it is unknown if he will be good to go against the Seahawks on Sunday.

Justin Skule (T) Ques Sun Knee - 31 / 12 / 20 1-0 0-1 + -

Skule has a knee injury, and it remains to be seen if he will partake in Sunday's game against the Seahawks.

Jordan Willis (DL) out for season Ankle - 31 / 12 / 20 1-0 0-1 + -

Willis has been placed on the injured reserve list as he has an ankle injury, ending his season.

Robbie Gould (K) Out indefinitely Illness - 30 / 12 / 20 1-0 0-1 + -

Gould has landed on the Injured Reserve/COVID-19 list, and will be out for an unknown length of time.

Mark Nzeocha (LB) Ques Sun Illness - 30 / 12 / 20 1-0 0-1 + -

Nzeocha is ailing from an illness, and it is unknown if he will participate against the Seahawks on Sunday.

K'Waun Williams (CB) Out Sun Shin - 30 / 12 / 20 1-0 0-1 + -

Williams is managing a shin injury, and it will prevent him from playing against the Seahawks on Sunday.

Tarvarius Moore (DB) Ques Sun Ankle - 28 / 12 / 20 1-0 0-1 + -

Moore is dealing with an ankle injury, leaving his status against the Seahawks on Sunday hazy.

Brandon Aiyuk (WR) Out Sun Ankle - 28 / 12 / 20 1-0 0-1 + -

Aiyuk is battling an ankle injury, and he will not be available Sunday versus the Seahawks.

American Football Conference Standings

Team Win / Loss ATS OU
14-2 12-6 11-6-1
13-3 12-6 11-6-1
12-4 6-10 9-7
11-5 10-6 7-9
11-5 11-6 7-10
11-5 7-10 10-7
11-5 8-8 9-7
10-6 11-4 6-9
8-8 8-7 11-3-1
7-9 6-9 6-9
7-9 8-7 8-7
5-11 8-7 11-3-1
4-11 9-6 7-8
4-12 7-8 11-3-1
2-14 6-9 6-9
1-15 6-9 8-7

National Football Conference Standings

Team Win / Loss ATS OU
13-3 10-8 10-8
12-4 9-8 10-7
12-4 9-7 4-12
7-9 9-7 9-7
11-5 10-8 10-8
10-6 10-7 5-12
8-8 8-8 8-8
8-8 7-8 5-10
7-9 6-9 10-5
6-10 6-9 7-8
6-10 5-10 9-6
6-10 5-10 9-6
5-11 8-7 10-5
5-11 6-9 10-5
4-11 9-6 5-10
4-12 7-8 6-9