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Kansas Jayhawks vs. Iowa State Cyclones Odds, Stats - November 22, 2025

Final Score
Nov 22nd, 12:00 PM EST
Kansas
Jayhawks
Iowa State
Cyclones
14
38
Kansas Jayhawks
Iowa State Cyclones
Scoreboard 1 2 3 4 Odds
Kansas Jayhawks 5-7 0 0 14 0 +55.5
Iowa State Cyclones 8-4 7 10 14 7 -3.5

Latest Encounters

Date Result Competition Stats Recap
11/29/25
Iowa State Cyclones ISU ( 8-4 )
Oklahoma State Cowboys OKST ( 1-11 )
20   -   13
11/28/25
Utah Utes UTAH ( 10-2 )
Kansas Jayhawks KU ( 5-7 )
31   -   21
11/08/25
Kansas Jayhawks KU ( 5-7 )
Arizona Wildcats ARIZ ( 9-3 )
20   -   24
11/08/25
Iowa State Cyclones ISU ( 8-4 )
Texas Christian Horned Frogs TCU ( 8-4 )
20   -   17
11/01/25
Oklahoma State Cowboys OKST ( 1-11 )
Kansas Jayhawks KU ( 5-7 )
21   -   38
11/01/25
Arizona State Sun Devils ASU ( 8-4 )
Iowa State Cyclones ISU ( 8-4 )
24   -   19
10/25/25
Brigham Young Cougars BYU ( 11-2 )
Iowa State Cyclones ISU ( 8-4 )
41   -   27
10/25/25
Kansas State Wildcats KSU ( 6-6 )
Kansas Jayhawks KU ( 5-7 )
42   -   17
10/11/25
Kansas Jayhawks KU ( 5-7 )
Texas Tech Red Raiders TTU ( 12-1 )
17   -   42
10/11/25
Iowa State Cyclones ISU ( 8-4 )
Colorado Buffaloes COLO ( 3-9 )
17   -   24

Matchup Odds

Team Spread Moneyline Over / Under
Kansas Jayhawks KU
+3.5 0 0 U+55.50
Iowa State Cyclones ISU
-3.5 0 0 O+55.50

Line History

time fav line total
Opening 16 Nov 8:54pm KU O +55.5 -110
Closing 22 Nov 7:41pm KU U +52.5 -175

Line History

Team Leaders

Kansas Jayhawks KU
Iowa State Cyclones ISU
Leshon Williams
Running Back Iowa State
9 Touchdowns 6
Benjamin Brahmer
Tight End Kansas
Carson Hansen
Running Back Kansas
952 Rushing 587
Daniel Hishaw Jr.
Running Back Iowa State
Rocco Becht
Quarterback Kansas
2584 Passing 2531
Jalon Daniels
Quarterback Iowa State
Emmanuel Henderson Jr.
Wide Receiver Iowa State
45 Receiving 37
Benjamin Brahmer
Tight End Kansas
Leroy Harris III
Defensive End Iowa State
4.5 Sacks 3
Caleb Bacon
Linebacker Kansas
Tre Bell
Defensive Back Kansas
2 Interceptions 1
Taylor Davis
Safety Iowa State

Matchup Details

team win loss last 10 w/l streak ats money home away total
Kansas Jayhawks Kansas Jayhawks
5 5 3-7 3L 4-6 0 0-0 0-0 5-5
Iowa State Cyclones Iowa State Cyclones
6 4 6-4 3W 4-5 0 0-0 0-0 4-6

Recent Meetings

date home-away ats o/u ISU:Total Net Yards ISU:Net Rushing Yards ISU:Passing Yards KU:Total Net Yards KU:Net Rushing Yards KU:Passing Yards
11/22/2025 ISU 38 - KU 14 ISU -4.5 Under 55.5 462 221 241 323 132 191
11/09/2024 KU 45 - ISU 36 KU +3 Over 53 461 78 383 532 237 295
11/04/2023 ISU 21 - KU 28 KU +2.5 Under 54 361 74 287 333 75 258
10/01/2022 KU 14 - ISU 11 KU +3 Under 59 313 26 287 213 112 101
10/02/2021 ISU 59 - KU 7 ISU -34.5 Over 58 302 175 127 564 290 274
10/31/2020 KU 22 - ISU 52 ISU -27.5 Over 54.5 552 258 294 240 73 167
11/23/2019 ISU 41 - KU 31 KU +22.5 Over 58 493 165 328 489 117 372
11/03/2018 KU 3 - ISU 27 ISU -18.5 Under 49.5 394 121 273 332 147 185
10/14/2017 ISU 45 - KU 0 ISU -20.5 Under 62.5 106 62 44 318 106 212
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
11/28/2025 KU 21 - UTAH 31 L +13.5 Under 60.5 414 161 253
11/22/2025 ISU 38 - KU 14 L +4.5 Under 55.5 323 132 191
11/08/2025 ARIZ 24 - KU 20 W +5.5 Under 56.5 369 170 199
11/01/2025 KU 38 - OKST 21 L -24.5 Over 55.5 316 72 244
10/25/2025 KU 17 - KSU 42 L -2.5 Over 54.5 371 140 231
10/11/2025 TTU 42 - KU 17 L +14 Over 58.5 319 47 272
10/04/2025 UCF 20 - KU 27 W -3.5 Under 55.5 358 123 235
09/27/2025 KU 34 - CIN 37 L -6 Over 56.5 603 215 388
09/20/2025 KU 41 - WVU 10 W -11.5 Under 54.5 324 182 142
09/06/2025 MIZZ 42 - KU 31 L +5.5 Over 49.5 254 31 223
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
11/29/2025 OKST 13 - ISU 20 L -14 Under 49.5 229 27 202
11/22/2025 ISU 38 - KU 14 W -4.5 Under 55.5 462 221 241
11/08/2025 TCU 17 - ISU 20 W +6 Under 57.5 432 113 319
11/01/2025 ISU 19 - ASU 24 L -7.5 Under 48.5 336 150 186
10/25/2025 ISU 27 - BYU 41 L -2.5 Over 48.5 495 184 311
10/11/2025 COLO 24 - ISU 17 L -4.5 Under 51.5 395 140 255
10/04/2025 CIN 38 - ISU 30 L +1.5 Over 51.5 474 260 214
09/27/2025 ISU 39 - ARIZ 14 W -4.5 Over 49.5 399 111 288
09/13/2025 ARST 16 - ISU 24 L Over 0 387 165 222
09/06/2025 ISU 16 - IOWA 13 W -1.5 Under 43 238 104 134

Matchup Edge - Scoring Stats

Kansas Jayhawks KU
Iowa State Cyclones ISU
avg rank edge in rank avg
28.08 70 Points Per Game 76 27.42
26.75 89 Points Allowed Per Game 29 20.17
6.67 38 1st Quarter Scoring Per Game 38 6.67
7.5 77 1st Quarter Scoring Allowed Per Game 17 3.42
8.83 53 2nd Quarter Scoring Per Game 56 8.67
6.5 37 2nd Quarter Scoring Allowed Per Game 45 6.83
8.5 18 3rd Quarter Scording Per Game 47 6.33
5.17 45 3rd Quarter Scoring Allowed Per Game 53 5.67
4.08 94 4th Quarter Scoring Per Game 70 5.75
7.58 71 4th Quarter Scoring Allowed Per Game 21 4.25
72.3 86 Red Zone Efficiency 53 83.0
390.67 67 Total Yards Per Game 62 396.25
13.59 50 Total Yards Per Play 46 13.7
4.72 35 Rushing Yards Per Play 53 4.41
28.75 68 Passing Attempts Per Game 67 28.92
12.64 39 Passing Yards Per Completion 38 12.65
1.92 14 Passing Tds Per Game 25 1.33
17.58 67 Completions Per Game 68 17.5
61.2 66 Completion % 73 60.5
143.46 53 Qb Rating 73 134.87
1.67 29 Defense Sacks Per Game 25 1.83
0.67 13 Defense Interceptions Per Game 11 0.75
0.42 13 Opponent Fumbles Lost Per Game 13 0.42
5 45 Penalties Per Game 38 4.58
39.75 70 Penalty Yards Per Game 71 40
13 11 Takeaway / Giveaway Differential 12 14
3.12 61 Yards Per Punt Return 30 5
21.67 57 Yards Per Kickoff Return 126 17.27

Odds Analysis

Team Rankings

offence
Kansas Jayhawks KU
Season stats rank
Total Yards 390.7 67
Passing Yards 222.25 73
Rushing Yards 168.42 60
Points Scored 28.08 304
Field Goal % 0.82 82
Iowa State Cyclones ISU
Season stats rank
Total Yards 396.3 62
Passing Yards 221.42 75
Rushing Yards 174.83 51
Points Scored 27.42 327
Field Goal % 0.76 117
defence
Kansas Jayhawks KU
Season stats rank
Total Yards 390.7 67
Passing Yards 222.25 73
Rushing Yards 168.42 60
Points Scored 28.08 304
Field Goal % 0.82 82
Iowa State Cyclones ISU
Season stats rank
Total Yards 396.3 62
Passing Yards 221.42 75
Rushing Yards 174.83 51
Points Scored 27.42 327
Field Goal % 0.76 117

Injuries

Kansas Jayhawks KU
Iowa State Cyclones ISU

Betting News + Tweets

Kansas Jayhawks KU

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Iowa State Cyclones ISU

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Kansas Vs Iowa State Betting Trends

Kansas Jayhawks KU

Jayhawks are 4-9-1 ATS in their last 14 games as a road underdog of 3.5-10.0.

Jayhawks are 0-4 ATS in their last 4 games following a ATS win.

Jayhawks are 4-9 ATS in their last 13 games as a road underdog.

Under is 5-1 in Jayhawks last 6 games as a favorite of 10.5 or greater.

Under is 3-1-1 in Jayhawks last 5 games in November.

Iowa State Cyclones ISU

Under is 4-0 in Cyclones last 4 games as a home underdog of 3.5-10.0.

Cyclones are 1-4 ATS in their last 5 conference games.

Cyclones are 1-5-1 ATS in their last 7 games as a home underdog of 0.5-3.0.

Over is 8-2 in Cyclones last 10 games as a home underdog of 10.5 or greater.

Cyclones are 1-4-1 ATS in their last 6 games following a ATS win.

Line Up - Last Game

Kansas Jayhawks
Pitchers
POS Player
Hitters
POS Player
Iowa State Cyclones
Pitchers
POS Player
Hitters
POS Player
  • KU
  • +3.5 -3.5
  • ISU
NCAAF Odds