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Houston Astros vs. Cleveland Guardians Odds, Stats - April 21, 2026

Final Score
American League West
Apr 21st, 6:10 PM EDT
Houston
Astros
Cleveland
Guardians
5
8
Houston Astros
Cleveland Guardians
Scoreboard 1 2 3 4 5 6 7 8 9 R ML H E
Houston Astros 9-16 0 0 0 0 3 0 - - - 5 +130 10 0
Cleveland Guardians 14-11 1 1 0 0 0 0 - - - 8 -155 11 1

Latest Encounters

Date Result Competition Stats Recap
04/20/26
Houston Astros HOU ( 9-16 )
Cleveland Guardians CLE ( 14-11 )
9   -   2
 American League West
04/19/26
St. Louis Cardinals STL ( 14-9 )
Houston Astros HOU ( 9-16 )
7   -   5
 National League Central
04/19/26
Baltimore Orioles BAL ( 11-13 )
Cleveland Guardians CLE ( 14-11 )
4   -   8
 American League East
04/18/26
St. Louis Cardinals STL ( 14-9 )
Houston Astros HOU ( 9-16 )
7   -   5
 National League Central
04/18/26
Baltimore Orioles BAL ( 11-13 )
Cleveland Guardians CLE ( 14-11 )
2   -   4
 American League East
04/17/26
St. Louis Cardinals STL ( 14-9 )
Houston Astros HOU ( 9-16 )
9   -   4
 National League Central
04/17/26
Baltimore Orioles BAL ( 11-13 )
Cleveland Guardians CLE ( 14-11 )
6   -   4
 American League East
04/16/26
Colorado Rockies COL ( 9-15 )
Houston Astros HOU ( 9-16 )
3   -   2
 National League West
04/16/26
Baltimore Orioles BAL ( 11-13 )
Cleveland Guardians CLE ( 14-11 )
2   -   4
 American League East

Matchup Odds

Team Runline Moneyline Over / Under
Houston Astros HOU
+1.5 0 0 U+8.50
Cleveland Guardians CLE
-1.5 0 0 O+8.50

Line History

time fav line total
Opening 21 Apr 2:08am HOU O +8 -118
Closing 22 Apr 12:52am HOU O +11.5 -102

Line History

Team Leaders

Houston Astros HOU
Cleveland Guardians CLE
Yordan Alvarez
Left Outfield Cleveland
10 HR 6
José Ramírez
Third Base Houston
Christian Vázquez
Catcher Cleveland
0.4 BA 0.3
Daniel Schneemann
Second Base Houston
José Ramírez
Third Base Houston
11 SB 4
Cam Smith
Right Outfield Cleveland

Matchup Details

team win loss last 10 units home away o / u rl w/l rl units
Houston Astros Houston Astros
9 15 3-7 -10.77 7-6 2-9 17-7 9-15 -6.2
Cleveland Guardians Cleveland Guardians
13 11 5-5 4.17 7-4 6-7 12-12 14-10 2.85

Recent Meetings

date home-away ats o/u CLE:RBI CLE:Batting Average CLE:Home Runs HOU:RBI HOU:Batting Average HOU:Home Runs
04/21/2026 CLE 8 - HOU 5 CLE Over 8.5 8 .33 1 5 .3 0
04/20/2026 CLE 2 - HOU 9 HOU Over 7 2 .24 0 9 .34 3
07/09/2025 HOU 2 - CLE 4 CLE Under 7.5 4 .19 2 2 .19 0
07/08/2025 HOU 6 - CLE 10 CLE Over 7 10 .22 3 6 .28 0
07/07/2025 HOU 5 - CLE 7 CLE Over 7.5 7 .29 2 5 .16 3
06/08/2025 CLE 4 - HOU 2 CLE Under 7.5 2 .21 0 3 .28 1
06/07/2025 CLE 3 - HOU 5 HOU Over 7 4 .17 1 3 .17 1
06/06/2025 CLE 2 - HOU 4 HOU Under 7.5 4 .29 1 2 .28 1
09/28/2024 CLE 3 - HOU 4 HOU Under 7.5 2 .25 0 3 .26 1
09/27/2024 CLE 2 - HOU 5 HOU Under 8.5 4 .34 2 2 .1 0
05/02/2024 HOU 8 - CLE 2 HOU Over 9 2 .22 0 7 .3 1
05/01/2024 HOU 2 - CLE 3 CLE Under 8.5 3 .26 1 2 .2 1
04/30/2024 HOU 10 - CLE 9 HOU Over 9 9 .19 3 10 .29 3
08/02/2023 HOU 3 - CLE 2 HOU Under 9 2 .22 0 3 .3 2
08/01/2023 HOU 2 - CLE 0 HOU Under 7.5 0 0 0 2 .21 0
07/31/2023 HOU 7 - CLE 3 HOU Over 9.5 3 .28 0 6 .24 1
06/11/2023 CLE 5 - HOU 0 CLE Under 8 0 .13 0 5 .35 2
06/10/2023 CLE 4 - HOU 6 HOU Over 8 6 .27 1 4 .3 0
06/09/2023 CLE 10 - HOU 9 CLE Over 8 9 .29 1 9 .27 1
08/07/2022 CLE 1 - HOU 0 CLE Under 8 0 .07 0 1 .25 1
date score ats o/u RBI Batting Average Home Runs
04/21/2026 CLE 8 - HOU 5 L Over 8.5 5 .3 0
04/20/2026 CLE 2 - HOU 9 W Over 7 9 .34 3
04/19/2026 HOU 5 - STL 7 L Over 8.5 7 .21 0
04/18/2026 HOU 5 - STL 7 L Over 9 6 .25 3
04/17/2026 HOU 4 - STL 9 L Over 9 9 .28 2
04/16/2026 HOU 2 - COL 3 L Under 8.5 2 .27 1
04/15/2026 HOU 3 - COL 1 W Under 8.5 1 .1 0
04/14/2026 HOU 7 - COL 6 W Over 8.5 6 .32 3
04/13/2026 SEA 6 - HOU 2 L Over 7.5 1 .22 0
04/12/2026 SEA 6 - HOU 1 L Under 8 1 .17 1
date score ats o/u RBI Batting Average Home Runs
04/21/2026 CLE 8 - HOU 5 W Over 8.5 8 .33 1
04/20/2026 CLE 2 - HOU 9 L Over 7 2 .24 0
04/19/2026 CLE 8 - BAL 4 W Over 7 8 .25 2
04/18/2026 CLE 4 - BAL 2 W Under 7 4 .11 2
04/17/2026 CLE 4 - BAL 6 L Over 8 4 .21 1
04/16/2026 CLE 4 - BAL 2 W Under 8 4 .26 1
04/15/2026 STL 5 - CLE 3 L Under 9 5 .29 0
04/14/2026 STL 6 - CLE 5 L Over 9 6 .25 3
04/13/2026 STL 3 - CLE 9 W Over 8 3 .26 1
04/12/2026 ATL 13 - CLE 1 L Over 7 13 .48 1

Matchup Edge - Scoring Stats

Houston Astros HOU
Cleveland Guardians CLE
avg rank edge in rank avg
5.6 4 Runs Per 9 Innings 15 4.29
0.788 2 On Base Plus Slugging 13 0.704
0.261 3 Batting Average 14 0.231
30 5 Home Runs 8 26

Odds Analysis

Team Rankings

offence
Houston Astros HOU
Season stats rank
Runs / G 5.4 4
BA 0.26 3
OPS 0.79 3
HR 30 5
SB 12 26
Cleveland Guardians CLE
Season stats rank
Runs / G 4.2 20
BA 0.23 21
OPS 0.7 18
HR 26 13
SB 19 12
defence
Houston Astros HOU
Season stats rank
Runs / G 5.4 4
BA 0.26 3
OPS 0.79 3
HR 30 5
SB 12 26
Cleveland Guardians CLE
Season stats rank
Runs / G 4.2 20
BA 0.23 21
OPS 0.7 18
HR 26 13
SB 19 12

Injuries

Houston Astros HOU
Cleveland Guardians CLE

Houston vs. Cleveland Betting News

Houston Astros HOU

No posts found.
Cleveland Guardians CLE

No posts found.

Houston Vs Cleveland Betting Trends

Houston Astros HOU

Under is 50-23-3 in Astros last 76 Tuesday games.

Over is 7-0 in Astros last 7 games with the total set at 9.0-10.5.

Astros are 19-7 in their last 26 games with the total set at 11.0 or higher.

Over is 10-4 in Astros last 14 games as a favorite.

Astros are 2-6 in their last 8 when their opponent allows 5 runs or more in their previous game.

Cleveland Guardians CLE

Under is 9-4 in Guardians last 13 games vs. a right-handed starter.

Under is 3-1-2 in Guardians last 6 games with the total set at 9.0-10.5.

Guardians are 5-2 in their last 7 games with the total set at 11.0 or higher.

Over is 5-2 in Guardians last 7 games as a favorite.

Over is 5-1-1 in Guardians last 7 home games with the total set at 9.0-10.5.

Pitchers & Umpires

Today - Overall

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Ryan Weiss (R) - - - - - - 9-16 - - - - -
Parker Messick (-) - - - - - - 14-11 - - - - -

Today - Last 3

IP W-L ERA K BB SV TM W-L H WHIP AF AA OU
Ryan Weiss (R) - - - - - - 9-16 - - - - -
Parker Messick (-) - - - - - - 14-11 - - - - -
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Jason Alexander (-) 1.73 0 6.35 3 3 0 3 8 4 4 2 0 1.94 7:4
Spencer Arrighetti (-) 5.5 2-0 2.45 13 8 0 2 8 3 3 0 0 1.45 10:4
Hunter Brown (-) 5.1 1-0 0.84 17 6 0 2 5 1 1 0 0 1.03 6:5
J.P. France (-) 2.07 0 8.1 4 5 0 0 6 6 6 1 0 1.65 8:6
Colton Gordon (-) 2.37 0 8.59 11 1 0 1 14 7 7 4 0 2.05 5:2
Cristian Javier (-) 3.03 0-1 12.54 4 9 0 3 13 13 13 2 0 2.36 6:10
Lance McCullers Jr. (-) 5.03 1-1 6.2 21 9 0 4 18 14 14 2 0 1.33 18:8
Miguel Ullola (-) 1.7 0 10.13 4 6 0 0 6 6 6 3 0 2.25 2:5
Ryan Weiss (R) 2.57 0-2 6.5 22 14 0 2 25 14 13 5 0 2.17 11:8
Mike Burrows (-) 5.24 1-3 6.75 25 9 0 5 36 20 20 5 0 1.69 21:14
Tatsuya Imai (-) 2.73 1-0 7.27 13 11 0 3 7 7 7 0 0 2.08 8:2
Kai-Wei Teng (-) 1.61 1-0 1.65 16 6 0 0 7 3 3 2 0 0.8 17:7
Christian Roa (-) 1.17 0-1 5.19 6 7 0 0 10 5 5 1 0 1.96 6:6
Amilcar Chirinos (R) 0.2 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Wilmy Sanchez (-) 2 0 0 3 0 0 0 0 0 0 0 0 0 2:1
Trey Dombroski (-) 1.05 0-1 11.57 1 0 0 0 3 3 3 2 0 1.29 1:3
Joey Mancini (-) 2 0 0 1 2 0 0 0 0 0 0 0 1 2:0
Alex Santos II (-) 0.1 0 0 0 0 0 0 1 0 0 0 0 3 0:1
Nolan DeVos (-) 2 0 0 1 0 0 0 1 0 0 0 0 0.5 4:1
Dylan Howard (-) 2 0 0 2 1 0 0 2 0 0 0 0 1.5 2:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Logan Allen (-) 2.5 0-2 18 9 8 0 4 25 20 20 4 0 3.3 9:6
Tanner Bibee (-) 4.82 0-2 4.81 23 9 0 5 28 13 13 4 0 1.52 23:10
Slade Cecconi (-) 4.84 0-3 6.2 20 12 0 5 27 19 17 5 0 1.58 27:15
Daniel Espino (-) 1 0 0 3 0 0 1 1 0 0 0 0 0.5 1:0
Parker Messick (-) 6.04 3-0 1.76 29 8 0 5 19 6 6 1 0 0.88 30:9
Doug Nikhazy (-) 0.8 0 14.73 3 4 0 0 8 6 6 0 0 3.27 4:2
Gavin Williams (-) 5.84 3-1 2.12 40 17 0 5 13 7 7 4 0 1.01 27:12
Yorman Gomez (-) 1.55 0 10.8 1 4 0 0 5 4 4 1 0 2.7 5:1
Austin Peterson (-) 1.1 0 27 1 1 0 0 4 4 4 0 0 3.75 2:1
Trenton Denholm (-) 1.55 0-1 13.5 2 2 0 0 7 5 5 1 0 2.7 5:2
Tommy Mace (-) 1 0 6 4 1 0 0 2 2 2 1 0 1 4:1
Ryan Webb (-) 1 1-0 6 4 1 0 0 4 2 2 0 0 1.67 3:2
Zane Petty (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 1:0
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Bryan Abreu (-) 0.79 0-2 14.73 12 13 0 0 9 13 12 4 0 3 5:4
AJ Blubaugh (-) 1.5 2-2 6.6 13 9 0 0 15 11 11 3 0 1.6 10:14
Enyel De Los Santos (-) 1 0-1 4.5 7 2 0 0 7 4 4 1 0 1.13 6:8
Bryan King (-) 1.13 0-1 4.22 12 5 0 0 11 7 5 0 0 1.5 12:2
Jayden Murray (-) 2 0 4.5 5 4 0 0 4 2 2 0 0 2 1:4
Steven Okert (-) 0.93 0 3.18 9 5 0 0 6 4 4 1 0 0.97 8:5
Bennett Sousa (-) 1 0 3 2 2 0 0 1 1 1 0 0 1 3:2
Logan VanWey (-) 1.13 0-3 8 12 3 0 0 11 9 8 2 0 1.56 4:5
Cody Bolton (-) 2.7 0-1 5.4 11 7 0 2 7 5 5 1 0 1.68 6:4
Sam Carlson (-) 1.28 0 0 7 1 0 0 4 0 0 0 0 0.94 5:3
Michael Knorr (-) 1.03 0 2.7 3 1 0 0 4 2 1 0 0 1.5 3:5
Peter Lambert (-) 5 0-1 7.2 8 1 0 1 7 4 4 0 0 1.6 4:1
Hudson Leach (-) 1 0 0 3 0 0 0 2 0 0 0 0 0.67 2:2
Anthony Maldonado (-) 1.02 1-0 2.84 2 1 0 0 3 2 2 1 0 0.63 6:5
Roddery Munoz (-) 1.33 0 15.75 6 6 0 0 7 7 7 3 0 3.25 2:1
Alimber Santa (-) 1 0 3.6 6 6 0 0 5 2 2 0 0 2.2 8:0
Amos Willingham (-) 1 0-3 10.5 10 4 0 0 9 9 7 1 0 2.17 9:0
Tom Cosgrove (-) 1.03 1-0 2.35 5 2 0 0 3 2 2 1 0 0.65 6:4
Trey McLoughlin (-) 0.5 0 0 0 0 0 0 0 0 0 0 0 0 1:1
IP W-L ERA K BB SV G H R ER HR SO WHIP GB:FB
Franco Aleman (-) 0.8 0 4.91 2 3 0 0 5 2 2 1 0 2.18 5:3
Kolby Allard (-) 2.05 0 10.38 9 3 0 0 16 10 10 2 0 2.19 10:3
Joey Cantillo (-) 5.02 1-0 3.2 30 12 0 5 21 11 9 3 0 1.3 15:14
Matt Festa (-) 1.23 1-0 6.35 9 1 0 0 13 8 8 2 0 1.24 9:7
Hunter Gaddis (-) 1 0 6 6 1 0 0 3 2 2 1 0 1.33 1:1
Tim Herrin (-) 0.58 0-1 0 3 4 0 0 6 1 0 0 0 1.76 5:5
Erik Sabrowski (-) 0.85 0-1 3.38 18 5 0 0 5 4 4 1 0 0.94 2:7
Cade Smith (-) 1 2-0 4.5 15 4 0 0 13 7 6 1 0 1.42 9:8
Connor Brogdon (-) 0.92 2-2 6.52 9 2 0 0 9 9 7 3 0 1.14 10:9
Colin Holderman (-) 1.5 0 6 3 2 0 0 2 3 2 1 0 1.33 5:2
Shawn Armstrong (-) 0.85 1-0 4.22 13 7 0 0 8 5 5 2 0 1.41 6:6
Pedro Avila (-) 1.35 0 3.24 4 1 0 0 10 4 3 1 0 1.32 12:4
Tanner Burns (-) 1 0-1 4.5 2 3 0 0 3 2 2 0 0 1.5 5:2
Will Dion (-) 1.22 0 2.84 5 0 0 0 8 2 2 0 0 1.26 6:4
Codi Heuer (-) 0.89 0-1 9 11 5 0 0 11 8 8 1 0 2 6:3
Jack Leftwich (-) 0.64 0 0 5 0 0 0 0 0 0 0 0 0 3:2
Jake Miller (-) 0.4 0-1 16.2 3 3 0 0 0 3 3 0 0 1.8 1:0
Peyton Pallette (-) 1.46 1-1 3.38 11 4 0 0 7 4 4 1 0 1.03 7:4
Steven Perez (-) 0.67 0 4.5 3 2 0 0 2 1 1 1 0 2 2:1
Trevor Stephan (-) 0.78 0 2.7 5 4 0 0 3 1 1 0 0 2.1 4:1
Jack Carey (-) 0.5 0 0 0 1 0 0 1 0 0 0 0 2 3:0
Jay Driver (-) 0.75 0 3 2 1 0 0 3 1 1 0 0 1.33 2:5
Magnus Ellerts (-) 0.7 0 3.86 4 0 0 0 1 1 1 1 0 0.43 2:1
Matt Jachec (-) 0.55 0 0 2 1 0 0 0 0 0 0 0 0.75 0:0
Jack Jasiak (-) 0.7 0 3.86 4 0 0 0 2 1 1 0 0 0.86 2:1
Izaak Martinez (-) 0.7 0 0 1 1 0 0 1 0 0 0 0 0.86 3:0
Xavier Martinez (-) 0.6 0 0 1 3 0 0 0 0 0 0 0 1.8 1:2
Zane Morehouse (-) 0.6 0 16.2 2 2 0 0 2 3 3 0 0 2.4 1:2
Cam Schuelke (-) 0.55 1-0 0 5 3 0 0 1 0 0 0 0 1.5 1:2
Hunter Stanley (-) 0.55 0 0 1 1 0 0 0 0 0 0 0 0.38 2:2
Tyler Thornton (-) 0.7 0 19.29 5 4 0 0 2 5 5 2 0 2.57 1:1
Adam Tulloch (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Alaska Abney (-) 1 0 0 0 1 0 0 1 0 0 0 0 2 2:1
Ross Carver (-) 1 0 0 0 1 0 0 1 0 0 0 0 2 1:0
Sean Matson (-) 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0:0
Logan McGuire (-) 0.1 0 0 1 0 0 0 1 0 0 0 0 1.5 0:0
Reid Johnston (-) 0.1 0 0 1 0 0 0 0 0 0 0 0 0 0:0
Umpire G W-L AVG PIT STR B STR% STR_ BB K/BB HR O/U
Derek Thomas 0 0-0 0 0 0 0 0 0 0 0 0 0-0

Line Up - Last Game

Houston Astros
Pitchers
POS Player
SP Ryan Weiss
RP Colton Gordon
RP Kai-Wei Teng
RP Enyel De Los Santos
RP Bryan King
Hitters
POS Player
SS Carlos Correa
DH Yordan Alvarez
2B Jose Altuve
1B Christian Walker
3B Isaac Paredes
RF Cam Smith
C Yainer Diaz
CF Brice Matthews
LF Dustin Harris
Cleveland Guardians
Pitchers
POS Player
SP Parker Messick
RP Shawn Armstrong
RP Connor Brogdon
RP Tim Herrin
RP Peyton Pallette
RP Cade Smith
Hitters
POS Player
CF Steven Kwan
DH Chase DeLauter
3B José Ramírez
1B Kyle Manzardo
RF George Valera
2B Daniel Schneemann
LF Angel Martinez
C Austin Hedges
SS Brayan Rocchio
  • HOU
  • CLE
MLB Odds