St. Louis Blues vs. Colorado Avalanche Game 5 Prediction, NHL Odds

Jordan Ramsay | Updated May 24, 2022

It's win or you're done for the St. Louis Blues on Wednesday as they travel to Denver trailing 3-1 in their second-round playoff series against the Colorado Avalanche.

St. Louis
May 25, 2022, 8:00 PM ET
Pepsi Center
Puckline +1.5 -103
Moneyline +225
Over / Under o +6.5


Betting Action


Puckline -1.5 -117
Moneyline -272
Over / Under u +6.5


Betting Action


Public Enemy No. 1 made the biggest impact on Monday as Nazem Kadri‘s hat trick powered the Colorado Avalanche to a 6-3 victory over the St. Louis Blues in Game 4 of their second-round playoff series.  Kadri, who has received death threats following a collision with Blues goaltender Jordan Binnington in Game 3, had arguably the best game of his playoff career and now sees his Colorado Avalanche team one win away from punching their ticket to the Western Conference final.  Game 5 will go from Denver on Wednesday night.

Colorado is a -252 favourite to win Game 5, with a total of 6.5 on the NHL odds.

Blues vs. Avalanche NHL Playoffs Betting Odds

In an odd quirk, the road team has been dominant in this head-to-head, winning seven of the last nine meetings between the teams.  There has also been a consistent trend in terms of the total, with the Over hitting in eight of the last 10 games, including two of three in this playoff series.

St. Louis does have something going for them on Wednesday as they have won 10 of their last 13 road games and they’ve already won in Denver this series.  Unfortunately for the Blues, however, that Game 2 win was just their second victory in their last nine trips to Colorado.  St. Louis needs to win-out or they’re done, which lengthens their series odds to +903 underdogs.

With the intense turn this series has taken, the Avalanche will do everything they can to keep from going back to St. Louis.  Recent trends favour the Avs as they’ve won seven of their last eight games overall and 10 of their last 13 at home.  Their high scoring offence has hit the Over in five of eight playoff games this year.  Colorado now sits as a massive -3333 favourite to win the series.

The favoured exact series score sees the Avalanche winning in five games at -250.  The biggest long shot is a St. Louis comback in seven games at +1494.

St. Louis Blues

The Blues have their work cut out for them at this point.  They’ll need to win three straight games against the Avalanche and do it without Binnington.  St. Louis’ No. 1 goalie has been ruled out of this series with a lower-body injury following the collision with Kadri in Game 3.  Ville Husso has the reins now and made 31 saves on 36 shots in Game 4.  It was Husso’s first start since Game 3 of the first-round against Minnesota.  In five appearances and four starts in these playoffs, Husso has a 1-4 record with a 3.76 goals-against average and .884 save percentage.

David Perron scored twice on Monday, while Pavel Buchnevich also found the back of the net.  Perron’s first goal gave the Blues a 1-0 lead after the first period, despite being outshot 15-3 in the frame.  Ryan O’Reilly was held pointless for the first time in eight games and just the second time in these playoffs.

Colorado Avalanche

Kadri got the last laugh in Game 4 as his first career playoff hat trick has Colorado on the brink of their first appearance in the Western Conference final since 2002.  Erik Johnson, Devon Toews and Mikko Rantanen also scored, while Darcy Kuemper made 17 saves.  The Avalanche outshot St. Louis every period and 37-20 for the game.  They broke out early in the second period with three goals in less than a two-minute span and are now a perfect 4-0 on the road in the playoffs.  Teams that take a 3-1 lead are 296-31 in a best-of-7 NHL playoff series, although the Rangers overcame a 3-1 series deficit against the Penguins in the first-round this year.

NHL Prediction: Who Will Win Blues vs. Avalanche?