NFL Point Spreads Week 8: Best Picks Against the Spread

Payton Matthews | Updated Oct 22, 2018

It's hard to believe that some NFL teams will already have played half their regular-season schedule by next Monday night.

Here’s a quick look at all the Week 8 matchups with Sports Interaction’s NFL odds. Games Sunday unless noted. Atlanta, Dallas, Tennessee and the LA Chargers are on the bye.

Miami Dolphins at Houston Texans, Thursday

Houston is one of the hottest teams in the league, following a 0-3 start with four consecutive wins. They pulled an upset Sunday in Jacksonville even though QB Deshaun Watson reportedly is playing with a collapsed lung. That’s hockey player tough! Miami is expected to be without injured starting QB Ryan Tannehill for a third straight game and has gone 1-1 without him.

Point spread: Texans -7

Pick ATS: Houston

Philadelphia Eagles vs. Jacksonville Jaguars

This is the final London game of the season and kicks off at 9:30 a.m. ET. Jacksonville is the “home” team as it plays one game a year overseas. Their owner would love to move the team there permanently as he owns the London soccer team Fulham. This should be the debut of running back Carlos Hyde for Jacksonville after he was acquired late last week from Cleveland. Jags star running back Leonard Fournette is out injured. Not clear who might start at QB for the team as Blake Bortles was pulled from Sunday’s home loss to Houston and has been a turnover machine in a three-game losing streak. Cody Kessler didn’t do much better in his place.

Point spread: Eagles -3

Pick ATS: Philadelphia

New York Jets at Chicago Bears

Third game in a row for Chicago against an AFC East team – it lost the first two, at Miami and home Sunday to New England. The Bears’ defence was one of the league’s best in a 3-1 start but has been torched the past two weeks. The Jets were blown out Sunday at home by Minnesota as rookie QB Sam Darnold had his worst game as a pro.

Point spread: Bears -6.5

Pick ATS: Chicago

Tampa Bay Buccaneers at Cincinnati Bengals

The Bucs tried their best to give Sunday’s home game away to the Browns but won in overtime on Chandler Catanzaro’s 59-yard field goal, the longest in league history in OT. He had earlier missed a 40-yarder at the end of regulation as well as a point-after try. He’d probably out of a job if he hadn’t made that OT kick. Cincinnati was blown out Sunday night in Kansas City.

Point spread: Bengals -6

Pick ATS: Cincinnati

Seattle Seahawks at Detroit Lions

Seattle is off its bye week and plays for the first time since team owner and Microsoft co-founder Paul Allen died of cancer. The Lions got to .500 with Sunday’s 32-21 victory in Miami. Rookie Kerryon Johnson rushed for 158 yards and Detroit rushed for 248 yards total, the franchise’s most in 21 years.

Point spread: Lions -2.5

Pick ATS: Detroit

Denver Broncos at Kansas City Chiefs

The Broncos are on extra rest after destroying the Cardinals on their own field last Thursday. Denver returned two interceptions for touchdowns in the first quarter. Already the last meeting between these AFC West rivals. Kansas City rallied for a 27-23 win in Denver on a Monday night in Week 4.

Point spread: Chiefs -9

Pick ATS: Kansas City

Washington Redskins at New York Giants

It’s a short week for the Giants as they visited Atlanta on Monday. Washington is the only team in the NFC East with a winning record after beating Dallas on Sunday, 20-17. The Redskins’ run defence was terrific in holding Ezekiel Elliott to just 34 yards on 15 carries. Now they get to face Rookie of the Year favourite Saquon Barkley.

Point spread: Redskins -1

Pick ATS: NY Giants

Cleveland Browns at Pittsburgh Steelers

Pittsburgh is off its bye week and could have Pro Bowl running back Le’Veon Bell back. There have been mixed reports about whether he reports to the team this week. Bell hasn’t played yet, refusing to sign his franchise tender. The Steelers and Browns tied 21-21 in Week 1 as kickers on both teams missed winning field goals. Tyrod Taylor was the Cleveland starting QB then; now it’s rookie Baker Mayfield.

Point spread: Steelers -7

Pick ATS: Pittsburgh

Baltimore Ravens at Carolina Panthers

Carolina was an upset winner Sunday in Philadelphia, 21-17. The Panthers trailed the reigning Super Bowl champions 17-0 in the fourth quarter. It was the biggest comeback win in franchise history. The Ravens went the other way, blowing a 10-point fourth-quarter lead at home and losing to the Saints 24-23 when Justin Tucker missed a PAT in the final seconds – his first-ever missed PAT.

Point spread: Ravens -1

Pick ATS: Carolina

Indianapolis Colts at Oakland Raiders

The Raiders are off their bye week but have lost starting running back Marshawn Lynch for at least a month due to a groin injury. The Colts stopped a four-game losing streak with a 37-5 rout of visiting Buffalo on Sunday. Andrew Luck threw four TD passes. Kicker Adam Vinatieri scored five points to move within five of breaking Morten Andersen’s NFL career record (2,544).

Point spread: Pick’em

Pick ATS: Oakland

Green Bay Packers at Los Angeles Rams

Potential NFC Championship Game preview? These two squaring off for a trip to the Super Bowl would surprise few. The Packers are off their bye week, while the Rams remained the NFL’s only unbeaten team with Sunday’s victory in San Francisco. This is the highest underdog price that Packers QB Aaron Rodgers has ever been in his pro career.

Point spread: Rams -8.5

Pick ATS: Green Bay

San Francisco 49ers at Arizona Cardinals

Arizona was so bad offensively in last Thursday’s embarrassing 45-10 home loss to Denver that offensive coordinator Mike McCoy was fired. The Cardinals still have yet to reach 300 yards on that side of the ball this season.  Quarterback Josh Rosen threw two pick-sixes in the first quarter vs. Denver, becoming the first rookie quarterback in NFL history to accomplish that unwanted feat. The Niners dropped their fifth in a row Sunday, falling at home to the Rams.

Point spread: Pick’em

Pick ATS: Arizona

New Orleans Saints at Minnesota Vikings

The Sunday night game and a rematch of last year’s divisional round playoff matchup, which the Vikings won in absolutely stunning and historic fashion. Minnesota’s Adam Thielen in Sunday’s win at the Jets became the first player in the Super Bowl era to record 100 yards receiving in each of his team’s first seven games. The Saints rallied from a 17-7 fourth-quarter deficit Sunday and won 24-23 in Baltimore thanks to a missed PAT.

Point spread: Vikings -1.5

Pick ATS: Minnesota

New England Patriots at Buffalo Bills, Monday

The clear mismatch of the week. The Patriots won their fourth straight Sunday, 38-31 in Chicago thanks in large part to two special teams touchdowns. Good-looking rookie running back Sony Michel left injured, however. The Bills are pretty clearly the NFL’s worst offensive team and that was evident in Sunday’s 37-5 loss at Indianapolis. Derek Anderson, just signed off the street a few weeks ago, started his first NFL game at QB since December 2016 and it went badly.

Point spread: Patriots -13

Pick ATS: Buffalo

NFL Week 8 Odds and Picks ATS

Time (ET)MatchupOddsPick ATS
8:20PMMiami Dolphins at Houston TexansTexans -7Houston
9:30AMPhiladelphia Eagles vs. Jacksonville JaguarsEagles -3Philadelphia
1:00PMNew York Jets at Chicago BearsBears -6.5Chicago
1:00PMTampa Bay Buccaneers at Cincinnati BengalsBengals -6Cincinnati
1:00PMSeattle Seahawks at Detroit LionsLions -2.5Detroit
1:00PMDenver Broncos at Kansas City ChiefsChiefs -9Kansas City
1:00PMWashington Redskins at New York GiantsRedskins -1NY Giants
1:00PMCleveland Browns at Pittsburgh SteelersSteelers -7Pittsburgh
1:00PMBaltimore Ravens at Carolina PanthersRavens -1Carolina
4:05PMIndianapolis Colts at Oakland RaidersPick'emOakland
4:25PMGreen Bay Packers at Los Angeles RamsRams -8.5Green Bay
4:25PMSan Francisco 49ers at Arizona CardinalsPick'emArizona
8:20PMNew Orleans Saints at Minnesota VikingsVikings -1.5Minnesota
8:15PMNew England Patriots at Buffalo BillsPatriots -13Buffalo