2025 NFL Week 16: L.A. Rams vs. Seattle Seahawks TNF same-game parlay
It’s a heavyweight showdown on Thursday that could decide the NFC West as the L.A. Rams travel to Seattle to face the Seahawks.
In addition to the division, top spot in the conference is up for grabs between these two 11-3 teams. L.A. has dominated in recent head-to-head history, winning four of the last five matchups.
This week’s Thursday Night Football same-game parlay focuses on Matthew Stafford leading the Rams to victory in a lower scoring contest.
Here’s what I have for a three-leg parlay priced at +575:
- Rams +1 (-118)
- Total Under 42.5 (-110)
- Matthew Stafford Over. 1.5 passing TDs (+105)
You can also take a look at our full game preview and score prediction here.
Don’t forget to check out Sports Interaction’s complete list of NFL game odds, NFL futures and NFL specials and props.
Rams +1
I’m pretty surprised at the line movement in this game. L.A. actually opened as a 1.5-point favourite, but early money coming in on the Seahawks has flipped the spread in Seattle’s favour.
That likely comes down to bettors believing it’s hard to win divisional games on the road and it’s hard to sweep a divisional season series. The Rams took a close home decision, 21-19, back in Week 11.
The trends all point to Los Angeles in this spot. They close out season’s strong, going 17-3 against the spread in their last 20 December games, and they’ve won five straight games at Lumen Field.
On the flip side, you have a Seahawks team that barely got by 44-year-old grandfather Philip Rivers last week, 18-16, as 13-point favourites. Plus, Sam Darnold has seriously cooled off with no TD passes in two of his last three games.
Darnold is 0-3 against the Rams since the start of last season. This team just has Darnold’s number, so I’ll take L.A. as a short road dog.
Under 42.5
I obviously liked the total better when it opened at 45.5, but I think it’s still worth taking the Under despite early betting action lowering it three full points.
Seattle has the second-best scoring defence in the NFL, limiting opponents to just 17.3 points per game, while the Rams are tied with Denver for third at 18.6 ppg. After some serious math calculations, that’s an average game total of 35.9 points.
The teams combined to finish below this number in their first meeting this year and even in that game, the total was at 26 combined points in the fourth quarter before each team scored a late touchdown.
I expect a tight, defensive game, not a shootout.
Matthew Stafford Over 1.5 passing TDs
Taking Matthew Stafford to throw multiple touchdown passes seems like free money in my mind.
The favourite to win MVP has thrown two or more touchdown passes in eight straight games and 12 of 14 this season. He also finished with two touchdown passes in that Week 11 game against the Seahawks.
And as good as Seattle’s total defence is, they’re still clearly better at defending the rush. L.A. should focus on the passing attack, with Stafford connecting multiple times in the end zone.
