Saints vs. Rams Point Spread: NFL Week 16 Odds, Prediction

Payton Matthews | Updated Dec 18, 2023

It’s a potentially big game in the NFC playoff race to kick off Week 16 as the Saints visit the Rams in the penultimate Thursday night game of the 2023 regular season.

December 21, 2023, 8:15 PM ET
SoFi Stadium
L.A. Rams
Pointspread +4 -110
Moneyline +165
Over / Under o +46
Pointspread -4 -110
Moneyline -200
Over / Under u +46

The Rams opened as 4-point favourites on the NFL odds.

NFL Point Spread and Betting Analysis

While both teams enter at 7-7, the Saints are in a much better spot for making the playoffs because of not just the wild card but they also are tied for the NFC South lead with Tampa Bay, although the Bucs currently hold the tiebreaker and New Orleans sits eighth in the conference overall, one spot out of the final WC spot. 

Los Angeles, which can’t win the NFC West as it already has been clinched by San Francisco, imploded last season but Sean McVay has done a great job this year, and the Rams are the NFC’s final wild card team as things stand because as of now they win the tiebreak over New Orleans based on best win per centage in conference games. Needless to say, the head-to-head result will trump all. 

Including a couple of playoff matchups and dating to the Rams’ days in St. Louis, they lead the all-time series 43-35-0. They played Week 11 last year in New Orleans and the Saints won 27-20 as Andy Dalton, now a backup with Carolina, had one of the best games of his career in completing 21 of 25 for 260 yard and three scores for a 149.6 rating that’s not far from perfect. Rams counterpart Matthew Stafford also was good in completing 11-for-18 for 159 yards and two scores before leaving to be evaluated for a concussion in the second half. The former No. 1 overall pick would not end up playing again last season.

New Orleans Saints

The Saints played without No. 1 WR Chris Olave on Sunday but still managed to beat the Giants 24-6 to end New York’s three-game winning streak. Derek Carr has been very up-and-down this season but was up Sunday with three TD passes, only five incompletions and no turnovers. Carr has 3,098 passing yards this season and became the third player in NFL history with at least 3,000 passing yards in each of his first 10 career seasons, joining Peyton Manning and Russell Wilson. If New Orleans can score 24 points each game, it’s going to be in the playoffs because it has a very good defence. Tanoh Kpassagnon had three sacks against New York, and New Orleans totaled seven sacks while holding the Giants to 60 net rushing yards. “There have been a couple other games … where I feel like we put a complete game together,” said coach Dennis Allen, who is on a bit of a hot seat. “I do feel like this was a complete game for our team.” Not clear if Olave, the 2022 Offensive Rookie of the Year runner-up, will be able to return from his ankle injury in a quick turnaround. The Saints are also eligible to open the practice window for wide receiver and former Offensive Player of the Year Michael Thomas this week.

Los Angeles Rams

Los Angeles entered its Week 9 bye at 3-6 and on a three-game skid but is now 7-7 following Sunday’s 28-20 win over Washington. Matthew Stafford deserves Comeback Player of the Year votes as he threw two more TD passes in the win, his fourth straight game with multiple TD throws and third straight without a pick. Stafford connected with Cooper Kupp on a 62-yard TD, Kupp’s longest since a 69-yard receiving score against the Tampa Bay Buccaneers in Week 9 last season. It was his eighth career receiving touchdown of 50-plus yards, which is the most by any Rams player since the 1970 merger. Kyren Williams wasn’t even the No. 1 back when this season started but is having a Pro Bowl-calibre season as he rushed for 152 yards and a TD on 27 carries. He’s up to 11 total TDs. WR Tutu Atwell and offensive tackle Rob Havenstein both were out injured but should play Thursday. Ditto cornerback Akhello Witherspoon, who left with an injury. 

NFL Prediction: Who Will Win Saints vs. Rams?

NFL Predictions