The last of three Saturday games in Week 16 is also the final Saturday matchup of the 2019 regular season (there will be a few in the playoffs) as the Los Angeles Rams visit the San Francisco 49ers in an important NFC West matchup.

NFL Point Spread and Betting Analysis

The Rams are two-time NFC West champions, but they will relinquish that title this season to these 49ers or else the Seattle Seahawks. It could be decided in Week 17 when San Francisco visits Seattle. San Francisco, which has clinched at least a Wild-Card spot, hasn’t won the West since 2012.

The 49ers go for the season sweep as they beat the host Rams 20-7 in Week 6, Los Angeles’ third loss in a row at the time. San Francisco’s defence is one of the NFL’s best and that was on display after the Rams scored a touchdown on their opening possession. They obviously didn’t score again and finished with just 157 total yards. Jared Goff looked overwhelmed, sacked four times and completing 13 of 24 for a career-low 78 yards. The Rams didn’t have a completion longer than 12 yards while going 0 for 9 on third down and 0 for 4 on fourth down. Didn’t help that star running back Todd Gurley was out with a bruised thigh.

Jimmy Garoppolo passed for 243 yards and ran for a touchdown for the Niners. Pro Bowl tight end George Kittle caught eight balls for 103 yards. San Francisco didn’t score a TD in the final 27 minutes, settling for two Robbie Gould field goals.

The Rams are 2-6 against the spread (ATS) in the past eight meetings. The under is 5-1 in the previous six at the 49ers.

Los Angeles Rams

The Rams are defending conference champions but the only way they can get a Wild-Card spot now is to win out and have the Minnesota Vikings lose their final two games. The Vikings are home to Green Bay on Monday in Week 16 and home to a nothing-to-play for Bears team in Week 17. Los Angeles was a short favourite in Dallas in Week 15 but was routed 44-21. The Rams were outgained 475-289. They rushed for 3 yards in the first half and finished with a total of 22 rushing yards. Starting cornerback Troy Hill injured his thumb and will have surgery this week yet still might play Saturday. The Rams are 5-1 ATS in their past six vs. the NFC West.

San Francisco 49ers

The 49ers are in the playoffs, but they come off a shocking 29-22 home loss to a bad Falcons team. Atlanta went ahead on a 5-yard TD pass from Matt Ryan to Julio Jones with two seconds left. Then, probably the worst “bad beat” of the season happened on the total, which was set at 50. On the ensuing kickoff, the Niners tried a trick play, but it would end up being recovered in the end zone by Atlanta and that 29-22 final. The 49ers became the first team to win 10 games in a season and also lose at least three games in the final 10 seconds of regulation or overtime since the 2000 Philadelphia Eagles. San Francisco would still be the West champion and conference’s top seed by winning out. Right now, though, it would be a Wild-Card team. The Niners are 7-18-1 ATS in their past 26 as favourites.

Who Will Win Rams vs. 49ers?

Weather

temp	58
condition	cloudy
wind	Southwest 12mph

Injuries

L.A. Rams

Michael Brockers (DL)

Doub Sun Knee - 25 / 12 / 19

Nsimba Webster (WR)

Prob Sun Concussion - 25 / 12 / 19

Eric Weddle (S)

Ques Sun Groin - 25 / 12 / 19

Andrew Whitworth (T)

Doub Sun Quadricep - 25 / 12 / 19

Darrell Henderson (RB)

I-R Ankle - 22 / 12 / 19

Jared Goff (QB)

Prob Sat Thumb - 16 / 12 / 19

Greg Zuerlein (K)

p Quadricep - 16 / 12 / 19

Troy Hill (CB)

Out Sun Thumb - 15 / 12 / 19

Nsimba Webster (WR)

Prob Sun Hip - 11 / 12 / 19

Jojo Natson (WR)

I-R Hamstring - 02 / 12 / 19

San Francisco

Dante Pettis (WR)

Out Sun Illness - 23 / 01 / 20

Kwon Alexander (LB)

Prob Sun Pectoral - 22 / 01 / 20

Dee Ford (DL)

Prob Sun Quadricep - 22 / 01 / 20

Jaquiski Tartt (S)

Prob Sun Ribs - 20 / 01 / 20

Tevin Coleman (RB)

Prob Sun Shoulder - 19 / 01 / 20

Kwon Alexander (LB)

Prob Sun Pectoral - 15 / 01 / 20

Tevin Coleman (RB)

Prob Sun Ankle - 15 / 01 / 20

Dee Ford (DL)

Prob Sun Hamstring - 15 / 01 / 20

Raheem Mostert (RB)

Prob Sun Calf - 15 / 01 / 20

Joe Staley (T)

Prob Sun Shin - 15 / 01 / 20

Injuries

L.A. Rams

player (position)	status		ats*current	o/u*	notes
Michael Brockers (DL)	Doub Sun	Knee - 25 / 12 / 19	1-0	1-0	+ -
Brockers has a knee injury, and it is unlikely that he will play against the Cardinals on Sunday.
Nsimba Webster (WR)	Prob Sun	Concussion - 25 / 12 / 19	1-0	1-0	+ -
Webster is dealing with concussion-like symptoms, but it is expected that he will be cleared in time to face the Cardinals on Sunday.
Eric Weddle (S)	Ques Sun	Groin - 25 / 12 / 19	1-0	1-0	+ -
Weddle has a groin injury, and it is unknown if it will affect his status for Sunday's clash with the Cardinals.
Andrew Whitworth (T)	Doub Sun	Quadricep - 25 / 12 / 19	1-0	1-0	+ -
Whitworth is managing a quadriceps injury, and he is not expected to suit up against the Cardinals on Sunday.
Darrell Henderson (RB)	I-R	Ankle - 22 / 12 / 19	1-1	2-0	+ -
Henderson is on injured reserve with a high-ankle sprain.
Jared Goff (QB)	Prob Sat	Thumb - 16 / 12 / 19	1-1	2-0	+ -
Goff is expected to suit up against the 49ers on Saturday despite a thumb contusion.
Greg Zuerlein (K)	p	Quadricep - 16 / 12 / 19	1-1	2-0	+ -
Zuerlein has a right quadriceps strain, but he is expected to suit up for Saturday's matchup against the 49ers.
Troy Hill (CB)	Out Sun	Thumb - 15 / 12 / 19	2-1	2-1	+ -
Hill missed the previous game with a broken thumb, and he will not be available to play the Cardinals on Sunday.
Nsimba Webster (WR)	Prob Sun	Hip - 11 / 12 / 19	2-1	2-1	+ -
Webster has a hip injury, but he is expected to suit up Sunday against the Cowboys.
Jojo Natson (WR)	I-R	Hamstring - 02 / 12 / 19	3-1	2-2	+ -
Natson has wound up on the injured reserve list with a hamstring injury.

San Francisco

player (position)	status		ats*current	o/u*	notes
Dante Pettis (WR)	Out Sun	Illness - 23 / 01 / 20	1-0	1-0	+ -
Pettis is fighting off an illness, and he will not be active for the 2020 Super Bowl versus the Chiefs.
Kwon Alexander (LB)	Prob Sun	Pectoral - 22 / 01 / 20	1-0	1-0	+ -
Alexander has a pectoral injury, but he is projected to take on the Chiefs in the 2020 Super Bowl.
Dee Ford (DL)	Prob Sun	Quadricep - 22 / 01 / 20	1-0	1-0	+ -
Ford is dealing with injuries to his quadriceps and hamstring. It is anticipated that he will partake in the 2020 Super Bowl versus the Chiefs.
Jaquiski Tartt (S)	Prob Sun	Ribs - 20 / 01 / 20	1-0	1-0	+ -
Tartt is dealing with a rib injury, but he is expected to line up against the Chiefs in the 2020 Super Bowl.
Tevin Coleman (RB)	Prob Sun	Shoulder - 19 / 01 / 20	2-0	1-1	+ -
Coleman has a right shoulder dislocation but is expected to play against the Chiefs in the 2020 Super Bowl.
Kwon Alexander (LB)	Prob Sun	Pectoral - 15 / 01 / 20	2-0	1-1	+ -
Alexander has a pectoral injury, but he is likely to suit up for the NFC championship game against the Packers.
Tevin Coleman (RB)	Prob Sun	Ankle - 15 / 01 / 20	2-0	1-1	+ -
Coleman is tending to an ankle injury, but it is not expected to impede his status for the NFC championship game against the Packers.
Dee Ford (DL)	Prob Sun	Hamstring - 15 / 01 / 20	2-0	1-1	+ -
Ford is dealing with a hamstring injury, but it is projected that he will line up against the Packers in the NFC championship game.
Raheem Mostert (RB)	Prob Sun	Calf - 15 / 01 / 20	2-0	1-1	+ -
Mostert is tending to a calf injury but is projected to take on the Packers in the NFC championship.
Joe Staley (T)	Prob Sun	Shin - 15 / 01 / 20	2-0	1-1	+ -
Staley is hampered by a fibula injury, but he is likely to face the Packers in the NFC championship game.