Packers vs. Saints Point Spread: NFL Week 1 Odds, Prediction

Payton Matthews | Updated Sep 01, 2021

It’s a new era for the Saints as they will begin life without future Hall of Fame quarterback Drew Brees. Jameis Winston gets the QB1 job in New Orleans' season-opener against the Green Bay Packers

Green Bay
September 12, 2021, 4:25 PM ET
TIAA Bank Field
Pointspread -4 -110
Moneyline -211
Over / Under o +50


Betting Action


Pointspread +4 -110
Moneyline +175
Over / Under u +50


Betting Action


The New Orleans Saints are the home team for their NFL Week 1 matchup vs. the Green Bay Packers on Sunday, Sept. 12, but the game will not be played in New Orleans due to hurricane damage. The Packers are 4-point favourites to win on the NFL odds.

NFL Point Spread and Betting Analysis

Hurricane Ida caused devastation in Louisiana and the Saints left the city of New Orleans ahead of the monster storm to practice, etc., in Dallas. While the New Orleans Superdome didn’t sustain major damage, many other parts of the city did – it may not be back to normal for weeks — and thousands remain without power.

Thus, the NFL had no choice but to move this game. It was never going to be played in Green Bay and give the Packers home-field advantage. Most thought it would be moved to Dallas since the Saints already are there and it’s close to New Orleans, but instead it will be played in Jacksonville, Fla. It’s certainly a bit of a break for Green Bay that it will be at a neutral site.

The favourite is 6-2 against the spread in the past eight meetings between these teams. Green Bay, though, was a 3.5-point underdog Week 3 in New Orleans last year and won 37-30. Aaron Rodgers threw for 283 yards and four scores. Drew Brees had 288 yards passing and three scores. More on both below.

Green Bay Packers

This could be the final season opener in a Packers uniform for Rodgers, the reigning NFL MVP and a +857 second-favourite on the NFL player props odds to win a fourth career MVP this season. Rodgers not wanting to play for the Packers was arguably the biggest NFL offseason story, but the sides came to an agreement that the team will trade him after this season if Rodgers still wants it.

Frankly, it never made sense for Rodgers to leave because this is still a Super Bowl-calibre team. Green Bay was the No. 1 seed in last season’s NFC playoffs but they were upset in the conference title game at home by Tom Brady and the Bucs. For the most part, every key player is back for the Pack, but All-Pro left tackle David Bakhtiari, who tore his ACL late last year, will miss at least the first six games on the PUP list. Pro Bowl linebacker Za’Darius Smith, who had 12.5 sacks and four forced fumbles in 2020, is in question for the opener with back troubles. Green bay is 7-1 ATS in its past eight September games.

New Orleans Saints

It’s a new era for the Saints as they will begin life without future Hall of Fame quarterback Drew Brees, arguably the best regular-season QB in history, for the first time since 2005. New Orleans was good enough the past few years to potentially win a second Super Bowl ring for Brees, but something always seemed to go wrong in the playoffs. The Saints lost at home in the divisional round back in January to the Bucs despite leading 20-13 late in the third quarter.

Jameis Winston beat out Taysom Hill for the starting QB job in camp, although Hill will still be used as a do-it-all player. All-Pro receiver Michael Thomas, the 2019 NFL Offensive Player of the Year, will miss at least the first six games on the PUP list. So will defensive tackle David Onyemata (six-game suspension), and Pro Bowl kicker Will Lutz (surgery) could miss that long, too. The Saints are 7-2 ATS in their past nine vs. the NFC

NFL Prediction: Who Will Win Packers vs. Saints?