Cardinals vs. Patriots Point Spread: NFL Week 12 Odds, Prediction

Sports Interaction Staff | Updated Nov 26, 2020

Kyler Murray, Cardinals, 2020

Kyler Murray leads all NFL quarterbacks with 619 rushing yards and his 10 rushing TDs is second among all players.

November 29, 2020, 1:00 PM ET
Gillette Stadium
Pointspread -2 -110
Moneyline -120
Over / Under o +51


Betting Action


Pointspread +2 -110
Moneyline +100
Over / Under u +51


Betting Action


Second year quarterback Kyler Murray has forced his way into the MVP conversation.  Can he keep up his sizzling pace when the 6-4 Cardinals head to New England for a Week 12 matchup with the 4-6 Pats?

Both teams are coming off Week 11 road losses, but only Arizona has managed to string together a winning record this season.  The Cardinals are 2.5-point favourites on the NFL odds with a total of 49.5.

NFL Point Spread and Betting Analysis

Arizona hasn’t put up big scoring totals on the road, recently.  The under is 6-0 in the Cardinals last six games on field turf, 5-0 in their last five road games and 4-0 in their last four games as a road favourite.  Arizona is 0-3-1 against the spread (ATS) in their last four November games.

The under is 5-1 in the Patriots last six home games and New England is 8-1 ATS in their last nine games as a home underdog.  The Pats walked away with a win the last time these teams squared off, a 23-21 Week 1 victory in 2016.

Arizona Cardinals

Despite suffering a shoulder injury during last week’s 28-21 road loss to the Seahawks, Kyler Murray (still expected to play against the Pats) threw for 269 yards and two TDs.  His name has crept its way into MVP consideration as this season Murray has thrown for 2,644 yards, 19 TDs and has completed 68.3 per cent of his passes.  Murray’s run game has been even better as his 619 rushing yards leads all quarterbacks and his 10 rushing TDs is second among all players.

Although they only picked up 57 rush yards as a team against the Seahawks, Arizona’s run-game has been instrumental to the offence all year.  The Cardinals 5.2 yards per carry is first in the league, while they are second in rushing yards per game with 152.7.  With the severity of Murray’s shoulder injury unknown and the weak rush defence of the Patriots, Arizona will likely elect to go run-heavy this week.

New England Patriots

With the Tom Brady era over in New England it’s not exactly surprising to see the Pats struggling this year.  One positive takeaway from their 27-20 loss in Houston last week was Cam Newton’s passing game.  Newton threw for 365 yards and unbelievably only his first passing touchdown to a wide receiver this season.  That wide receiver was Damiere Byrd, who had a monster game with 132 receiving yards.  Unfortunately, the Pats seem to either be able to throw the ball or run it, but not both in the same game.  New England, a team reliant on the run game this year, only put up 86 rushing yards against Houston, the worst rushing defence in the NFL.

The Patriots’ defence hasn’t been any better.  They allow 121.8 rushing yards per game, 236.1 passing yards per game and were picked apart by Texans QB Deshaun Watson, last week.  Watson threw for 344 yards and two TDs.  The Patriots’ offence isn’t likely to put up big numbers this year, so they’ll need to lock things down defensively if they want to salvage this season.

Who Will Win Cardinals vs. Patriots?