Broncos vs. 49ers NFL Betting Odds, Picks: Purdy Leads NFL-Best Offence
The Denver Broncos look to win their third straight game when they visit the unbeaten San Francisco 49ers on Sunday afternoon.
Denver improved to 2-1 with a dramatic 30-26 victory over the Los Angeles Rams last week. The Broncos trailed 16-0 at halftime before Bo Nix threw two touchdown passes and scored the winning TD with 47 seconds remaining.
San Francisco improved to 3-0 with a 36-30 victory over Arizona. Brock Purdy threw for 297 yards and four touchdowns, while Christian McCaffrey rushed for 75 yards and a score.
The Broncos have won 10 consecutive games against NFC opponents.
Broncos vs. 49ers Kickoff, Weather, TV, Streaming Info
Kickoff is Sunday at 4:25 PM ET at Levi’s Stadium in Santa Clara, California. The game airs on CBS.
Sunny skies are expected on Sunday afternoon, with temperatures around 81 degrees at kickoff and only a 1% chance of rain. Winds are expected to be light at around 4 mph.
NFL Betting Odds, Point Spread, Trends
San Francisco is currently a 2.5-point home favourite on the NFL odds board, with the 49ers -150 on the moneyline. Denver is +125, while the total is 47.5 points.
The Broncos are 2-1 against the spread this season, while San Francisco is also 2-1 ATS.
Denver is averaging 20 points per game, while the 49ers are averaging 32.7. San Francisco has allowed no sacks through three games.
NFL Player Odds and Props
Denver Broncos
Bo Nix over 225 passing yards (-112)
Nix has thrown for 605 yards, four touchdowns and three interceptions through three games. He was held to 186 yards against the Rams but faces a San Francisco defence that allowed Arizona to throw for 280 last week.
Jaylen Waddle over 58 receiving yards (-111)
Waddle leads Denver with 150 receiving yards through three games. He was a full participant in Wednesday’s practice after briefly wearing a walking boot following the Rams game.
San Francisco 49ers
Brock Purdy over 240 passing yards (+102)
Purdy has thrown for 789 yards, nine touchdowns and only one interception. He has surpassed 250 passing yards in each of San Francisco’s first three games.
George Kittle over 64 receiving yards (-111)
Kittle leads the 49ers with 174 receiving yards and three touchdowns. He caught two fourth-quarter touchdown passes against Arizona and remains one of Purdy’s top targets.
Denver Broncos
Denver has won consecutive games despite needing fourth-quarter comebacks in both.
Nix has completed 60.2% of his passes, while Denver is averaging only 275 total yards per game. The Broncos’ defence has helped compensate, allowing 23.3 points per contest and producing two crucial interceptions against the Rams.
Denver also received encouraging injury news on Wednesday. Receivers Marvin Mims Jr. and Waddle took full part in practice, while defensive lineman Zach Allen was limited.
San Francisco 49ers
San Francisco has opened 3-0 behind one of the NFL’s highest-scoring offences.
Purdy has completed 72.3% of his passes, while McCaffrey has rushed for 166 yards and three touchdowns. Kittle leads the receiving corps with 174 yards.
The 49ers have significant injury questions, however. Nick Bosa, Mike Evans and Dre Greenlaw missed Wednesday’s practice with injuries, while Christian McCaffrey was given a rest day. Bosa is expected to miss Sunday’s game, while Evans could return to practice later in the week.
Denver has made a habit of late comebacks, but San Francisco’s offensive efficiency presents its toughest challenge yet.