Bills vs. Titans Point Spread: NFL Week 5 Odds, Prediction

Payton Matthews | Updated Oct 13, 2020

stefon diggs bills

One of the marquee matchups in Week 5 around the NFL features the Buffalo Bills visiting the Tennessee Titans.

October 13, 2020, 7:00 PM ET
Nissan Stadium
Pointspread -3.5 +105
Moneyline -165
Over / Under o +52


Betting Action


Pointspread +3.5 -126
Moneyline +137
Over / Under u +52


Betting Action


This game is off the board as of this writing because of COVID-19 issues on the Titans, but they should open as very short favourites on the NFL odds.

NFL Week 5 Point Spread and Betting Analysis

It’s important to note that there is a chance this game is postponed after Tennessee’s Week 4 home matchup vs. Pittsburgh was due to a COVID-19 outbreak on the Titans – 10 players reportedly have tested positive and another 10 staffers. Because of that, the team couldn’t even enter its facility all last week, much less practice.

Every day seemed to bring an additional positive test or two among Titans players. The NFL strengthened protocols league-wide after that. On Monday, the Titans returned all negative tests for the first time in a week. If they do again Tuesday, they should be allowed back in their facility Wednesday and able to practice.

Buffalo is 3-0 straight up and against the spread in the past three in this series and all three have gone under the total. The teams also played Week 5 last year in Nashville and the Bills prevailed 14-7. Josh Allen threw for 219 yards and two scores. Marcus Mariota was still the Titans’ QB then and Tennessee had just 252 yards offence. Derrick Henry rushed for 78 yards and the lone TD.

Buffalo Bills

Buffalo is 4-0 for the first time since 2008 (that team finished 7-9) and leads the AFC East. Allen is playing like an MVP candidate and threw for 288 yards and two scores and rushed for another in Sunday’s 30-23 game in Las Vegas. Allen joined Steve Grogan (1976 Patriots) as the only quarterbacks with at least two touchdown passes and one rushing touchdown in three of his team’s first four games of a season in league history. Allen did injure his shoulder Sunday but returned.

One of the best offseason acquisitions in the NFL has easily been Bills receiver Stefon Diggs, and he had 115 yards on six catches. Diggs is tied for the league lead with 403 yards receiving. After averaging just 19.6 points in 2019, the Bills have averaged 30.8 so far in 2020. Starting cornerback Levi Wallace left the Raiders game with an ankle injury.

Tennessee Titans

The three most notable Titans to have tested positive thus far have been receiver Adam Humphries, starting nose tackle DaQuan Jones and backup cornerback and rookie second-round pick Kristian Fulton (it’s possible any positive players could be cleared by this Sunday). The team could face major discipline from the league if found not to have followed all the protocols.

Tennessee is looking to start 4-0 for the second time in franchise history. The 2008 team did and finished 13-3 but lost in the Divisional Round of the playoffs. One semi-bright spot of Tennessee not playing last week is that top wideout AJ Brown wasn’t going to go with a bruised knee but should be ready for Week 5. Brown had a stellar rookie season in 2019 with 52 catches for 1,051 and eight TDs. He had five catches for 39 yards in the 2020 season opener and hasn’t played since.

NFL Prediction: Who Will Win Bills vs. Titans?