Bills vs. Lions Point Spread: NFL Pre-Season Week 1 Odds, Prediction

Jordan Ramsay | Updated Aug 10, 2021

The Detroit Lions are pressing hard in the pre-season and they'll roll out all of their starters, led by new QB Jared Goff, for at least a quarter of action against the Buffalo Bills on Friday.

August 13, 2021, 7:00 PM ET
Ford Field
Pointspread +2 -110
Moneyline +122
Over / Under o +36.5
Pointspread -2 -110
Moneyline -147
Over / Under u +36.5

The NFL pre-season continues on Friday night with the Buffalo Bills heading to Ford Field in Detroit to face the Lions.  The Bills look like serious contenders in the AFC after they made their first conference championship appearance since 1993, last year.  The Lions, on the other hand, are ushering in the Jared Goff era, but look like they’ll struggle in the NFC.

Buffalo is a 2-point favourite to win on the NFL pre-season odds, with a total of 37.

NFL Point Spread and Betting Analysis

The Bills have won the last four regular season meetings and last two pre-season meetings between these teams.  There was no pre-season last year because of COVID, but Buffalo downed Detroit 24-20 at Ford Field in the 2019 pre-season.

The last time these teams met in the regular season ended in a 14-13 Buffalo win in 2018 during Josh Allen‘s rookie year.  Allen threw for 204 yards and one touchdown.  Robert Foster (now in Miami) had 108 receiving yards and a TD on four receptions.  For Detroit, Matthew Stafford (now on the Rams) threw for 208 yards and a TD.  Kenny Golladay (now with the Giants) picked up 146 receiving yards on seven receptions.

On Sports Interaction’s NFL futures board, Buffalo’s regular season win total is set at 10.5 with the Over at -233.  Detroit has one of the lowest win totals in the league at 5.5, with the Under a -175 favourite.  The Bills are -500 to make the playoffs, while the Lions are -1000 to miss out.

Buffalo Bills

Although there hasn’t been official word yet, it’s unlikely Josh Allen will get many reps, if any, in this game.  The attention will go to the other quarterbacks on the roster, as former Bears QB Mitch Trubisky is still in open competition for the backup spot with Jake Fromm and Davis Webb.  Receiver Stefon Diggs did not practice on Monday because of a knee injury, but he was on the field with the offence, so he could hook up with Allen for a rep or two.  Receiver Emmanuel Sanders looks like he’s over a minor foot injury and practiced at full speed on Tuesday.  It also looks like left tackle Dion Dawkins will be off the COVID list.

Detroit Lions

The Lions roster looks quite a bit different this season, so first-time head coach Dan Campbell has already said all of his starters will play at least one quarter.  It will be the first time fans get to see new quarterback Jared Goff take the field in a game situation after he was traded for Matthew Stafford in the off-season.  Receivers Kalif Raymond and rookie Amon-Ra St. Brown both reportedly had good camps and should get the most looks from Goff.  Running back Dedrick Mills has been taking first-team offensive reps and should get the majority of carries if rookie Jermar Jefferson’s ankle keeps him out of the game.

The injuries are already starting to pile up for Detroit.  It’s unclear if cornerbacks Quinton Dunbar (personal) and Corn Elder (hamstring), as well defensive tackle Da’Shawn Hand (lower-body), tight end T.J. Hockenson (undisclosed) and receiver Quintez Cephus (head) will be available.

NFL Prediction: Who Will Win Bills vs. Lions?