Bears vs. 49ers Point Spread: NFL Week 16 Odds, Prediction

Payton Matthews | Updated Dec 17, 2018

nick mullens 49ers

It has been a hugely disappointing season for the San Francisco 49ers as they close out their home schedule for 2018 on Sunday against the playoff-bound Chicago Bears.

December 23, 2018, 4:05 PM ET
Levi's Stadium
Pointspread -4 -110
Moneyline -190
Over / Under o +44.5


Betting Action


Pointspread +4 -110
Moneyline +160
Over / Under u +44.5


Betting Action


The 49ers were a chic playoff pick entering this season because they closed the 2017 campaign with five straight wins under new starting quarterback Jimmy Garoppolo. However, Jimmy G, who is from the Chicago area and went to Eastern Illinois, tore his ACL in a Week 3 loss in Kansas City and that was essentially that for the Niners. They could land the No. 1 overall pick in the 2019 draft, though, and potentially come back with a vengeance next year.

NFL Point Spread and Betting Analysis

One big reason the Bears are NFC North champions for the first time since 2010? Their trade for star linebacker Khalil Mack from the Raiders on the eve of the season. The 49ers actually made Oakland an offer for Mack first, but the Raiders preferred Chicago’s because it was presumed the Bears would stink this season again and thus send back better draft picks than San Francisco would.

These teams played Week 13 last season in the Windy City and the Niners won 15-14 in what was Garoppolo’s first start with the team and the beginning of that season-ending five-game win streak. Former Bear Robbie Gould had all the San Francisco points, including the winning 24-yard field goal with eight seconds left.

Chicago is 1-4 ATS in its past five at San Francisco.

Chicago Bears

Frankly, the Bears have very little to play for the last two weeks as they are nearly a lock to be the NFC’s No. 3 seed and host a playoff game on Wild-Card Weekend (although the Rams’ upset loss Sunday night left open a shot at the No. 2 seed). Chicago wrapped up its first NFC North title since 2010 on Sunday by beating Green Bay 24-17 to eliminate their arch-rivals from playoff contention. Mitchell Trubisky bounced back from a lousy game vs. the Rams by throwing for 235 yards and two scores.

The Bears lead the NFL by a mile in defensive interceptions and had another Sunday, ending Aaron Rodgers’ NFL record streak of 402 passes without a pick. Safety Eddie Jackson, a likely Pro Bowler, had the pick (his sixth of the year) but also sprained his ankle. Don’t expect him to play this week.  The Bears can be overly cautious with any injured players now.

San Francisco 49ers

San Francisco’s chances of landing the top overall pick in the 2019 draft took a big hit Sunday as the Niners upset Seattle 26-23 in overtime – just two weeks after losing to those Seahawks by 27 points. Gould hit the winning field goal with 3:06 left in OT to snap a 10-game losing streak in the series for the 49ers.

Nick Mullens threw for 275 yards and a score. The undrafted free agent has been one bright spot this season and likely has earned himself a spot as the No. 2 quarterback next year behind Garoppolo. Top running back Matt Breida was questionable to play with an ankle injury. He did go but then injured the ankle in the fourth quarter.

Bears vs. 49ers Prediction