49ers vs. Vikings Point Spread: NFL Week 1 Odds, Prediction

Andrew Rogers | Updated Sep 05, 2018

With quarterback Jimmy Garoppolo now entering his first full season at the helm, more scoring could be the norm for the 49ers, but they face a tough test against Minnesota's defence.

September 09, 2018, 1:00 PM ET
U.S. Bank Stadium
Pointspread +6 -110
Moneyline +220
Over / Under o +46


Betting Action


Pointspread -6 -110
Moneyline -270
Over / Under u +46


Betting Action


What carries a team with a stout defense into uncharted territory? The Vikings hope the answer to that question is a gun-slinging quarterback and a healthy franchise running back as they kick off their season Sunday afternoon against visiting San Francisco. With Kirk Cousins under center and Dalvin Cook close to 100 percent following last season’s devastating knee injury, Minnesota comes into the season with high hopes – and strong Super Bowl odds to boot.

NFL Point Spread and Betting Analysis

With the Vikings entering the season in the mix at +1,100 to win the Super Bowl, it’s no surprise that they’re favoured by nearly a touchdown against a 49ers team that earned five of its six wins over the final five weeks of the season. Minnesota has been ruthless in recent September home games, having won six straight while covering in each of them. Five of those victories came by double digits, with the Vikings averaging exactly 30 points in the six contests.

The total sits at 46, as bettors navigate a game featuring plenty of unknowns on both sides. The 49ers finished last season with three straight over conversions while averaging better than 34 points over that span – and with QB Jimmy Garoppolo now entering his first full season at the helm, more scoring could be the norm in San Fran. Minnesota, meanwhile, adds a talented QB in Cousins to a team that went 1-4 O/U over its final five regular-season games in 2017.

San Francisco 49ers

While the majority of the focus in San Francisco is on Garoppolo as the 49ers’ offensive saviour, this team has already been dealt a significant blow with the loss of No. 1 running back Jerick McKinnon to a season-ending knee injury. The 49ers ranked 21st in rushing yards last season, and having to rely on Alfred Morris and Matt Breida in the backfield could hamper their chances of going over on their win total of 8.5, a bet that presently pays out at +101.

Minnesota Vikings

The Vikings find themselves at the other end of the running back spectrum, with their No. 1 man returning to the fold after missing the majority of the 2017 campaign with a knee injury. Cook will lead a ground attack that produced the seventh-most rushing yards in football even with him only appearing in three games. Minnesota has a lofty 10-win Vegas total, and is a -131 favourite to surpass that number.

49ers vs. Vikings Prediction