Dolphins vs. Colts Week 10 Betting Odds, Prediction and Picks: Indianapolis Tries to Stop the Slide
The Miami Dolphins take on the Indianapolis Colts on Sunday afternoon in Week 10 of the NFL season.
Neither team has found much positivity this season. Miami enters with a 1-7 record, which puts them at the bottom of the AFC East standings.
On the other side, the Colts are 2-7 and have started trading away their veterans, leaving their current roster severely depleted and inexperienced.
The Colts won the most recent meeting 33-8 last season in Indianapolis on September 7, 2025. The Colts have dominated this series, winning eight of their last 10 head-to-head meetings with the Dolphins.
Dolphins vs. Colts Kickoff, Weather, TV, Streaming Info
Kickoff is set for 1 p.m. ET on Sunday at Lucas Oil Stadium in Indianapolis. The game airs on CBS in the United States. In Canada, it can be streamed nationwide on DAZN through NFL Game Pass, with selected Sunday afternoon games also available on CTV or RDS depending on regional coverage.
Conditions in Indianapolis are expected to be cool, with temperatures around 6 to 8°C and clear skies. Lucas Oil Stadium has a retractable roof, so weather is unlikely to play much of a role.
NFL Betting Odds, Point Spread, Trends
Playing at home, oddsmakers are giving Indianapolis a slight edge. The Colts are 3.5-point favourites, with moneyline odds of -192. The Dolphins have odds of +160 on the moneyline while the total is listed at 38.5.
Spread
NFL Player Odds and Props
Miami Dolphins
Miami RB Ollie Gordon II could see plenty of opportunities in this one. Kyle McCord is making his first-ever NFL start, so establishing the run could be key for Miami.
Gordon has taken over Miami’s RB1 role after De’Von Achane’s season-ending injury in Week 3. On the season, Gordon has rushed 107 times for 463 yards (4.3 yards per carry) and four scores.
Dolphins vs. Colts Player Props
Indianapolis Colts
Jonathan Taylor’s usage will be interesting to watch in this one. Taylor’s name continues to be surrounded by trade rumours, and there’s a legitimate chance this could be his last game as a Colt.
Taylor ran 13 times for 46 yards last week against the Cowboys. On the season, he has collected 656 yards and eight touchdowns on 161 attempts (4.1 yards per carry).
Miami Dolphins
The Jeff Hafley era in Miami is off to a rough start. The Dolphins have just one win this season, which came in Week 7 by a score of 28-25 against the Jets.
Miami’s offence has struggled mightily to find consistency. On the season, the Dolphins rank 31st in points per game (15.8) and 28th in total yards of offence per game (282.3).
Injuries have added to Miami’s problems. Most notably, QB Malik Willis recently landed on IR with a groin injury, and he is slated to miss at least four weeks.
With Willis sidelined, the Dolphins will turn to backup Kyle McCord, who they traded for in August. McCord has never attempted a pass in the NFL.
Indianapolis Colts
Going back to last season, the Colts have lost 14 of their last 16 games. A rebuild is already in motion, as Indianapolis has traded away a handful of veteran players over the last few weeks.
So far, the Colts have traded away DT DeForest Buckner, OT Quenton Nelson, WR Keenan Allen, and WR Josh Downs. The franchise has received some much-needed draft capital in return, but the Colts may not be done selling.
With the trade deadline looming, the biggest question surrounding the Colts right now is if star RB Taylor will get traded. Taylor would generate a significant return, so it will be interesting to see what the Colts decide to do.
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