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Panthers vs. Bills Prediction, Odds & Stats August 15, 2026

Final Score
NFC South
Aug 15th, 1:00 PM EDT
Carolina
Panthers
Buffalo
Bills
14
29
Carolina Panthers
Buffalo Bills
Scoreboard 1 2 3 4 Odds
Carolina Panthers 1-1 0 7 0 7 +0
Buffalo Bills 2-0 10 3 3 13
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Latest Encounters

Date Result Competition Stats Recap
09/20/26
Carolina Panthers CAR ( 1-1 )
Atlanta Falcons ATL ( 0-2 )
34   -   3
 NFC South
09/17/26
Detroit Lions DET ( 1-1 )
Buffalo Bills BUF ( 2-0 )
31   -   41
 NFC North
09/13/26
Chicago Bears CHI ( 1-1 )
Carolina Panthers CAR ( 1-1 )
59   -   37
 NFC North

Line History

Matchup Details

Carolina Panthers CAR
Buffalo Bills BUF
Stat
1 Games Won 0
0 Games Lost 0
1-1 Last 10 2-0
0-0 W L Streak 0-0
1-0 Against The Spread 0-0
0 Money 0
0-0 Home 0-0
0-0 Away 0-0
1-0 Total 0-0

Recent Meetings

date home-away ats o/u BUF:Total Net Yards BUF:Net Rushing Yards BUF:Passing Yards CAR:Total Net Yards CAR:Net Rushing Yards CAR:Passing Yards
08/15/2026 BUF 29 - CAR 14 BUF +1 Over 38 420 151 269 224 61 163
10/26/2025 CAR 9 - BUF 40 BUF -7.5 Over 48 410 245 165 244 114 130
08/24/2024 BUF 26 - CAR 31 CAR +4.5 Over 30.5 414 74 340 320 164 156
08/26/2022 CAR 21 - BUF 0 CAR -5 Under 38 191 81 110 238 50 188
12/19/2021 BUF 31 - CAR 14 BUF -12 Over 43.5 275 151 124 312 119 193
08/16/2019 CAR 14 - BUF 27 BUF +3 Over 40 373 94 279 258 103 155
08/09/2018 BUF 23 - CAR 28 CAR +1 Over 34 342 53 289 431 94 337
09/17/2017 CAR 9 - BUF 3 BUF +7 Under 43 176 69 107 255 77 178
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
09/20/2026 ATL 3 - CAR 34 W +1.5 Under 43 340 68 272
09/13/2026 CAR 37 - CHI 59 L +2.5 Over 45.5 552 291 261
08/28/2026 CAR 16 - HOU 13 W +1 Under 36.5 173 81 92
08/21/2026 JAC 17 - CAR 34 W +1 Over 40 385 147 238
08/15/2026 BUF 29 - CAR 14 L -1 Over 38 224 61 163
08/06/2026 ARI 30 - CAR 33 W -1.5 Over 35.5 378 141 237
date score ats o/u Total Net Yards Net Rushing Yards Passing Yards
09/17/2026 BUF 41 - DET 31 W -3 Over 52.5 446 203 243
09/13/2026 HOU 31 - BUF 36 W -1.5 Over 44.5 381 124 257
08/27/2026 BUF 28 - PIT 27 L -1 Over 35 266 89 177
08/22/2026 CLE 7 - BUF 31 W +1 Under 39.5 194 84 110
08/15/2026 BUF 29 - CAR 14 W +1 Over 38 420 151 269

Odds Analysis

Team Rankings

Carolina Panthers CAR
Season stats rank
Total Yards 419 30
Passing Yards 195 13
Rushing Yards 224 32
Points Scored 31 28
Field Goal % 0.67 5
Buffalo Bills BUF
Season stats rank
Total Yards 368 27
Passing Yards 273 30
Rushing Yards 95 13
Points Scored 31 30
Field Goal % 1 19
Carolina Panthers CAR
Season stats rank
Total Yards 409 5
Passing Yards 312.5 1
Rushing Yards 96.5 20
Points Scored 35.5 2
Field Goal % 1 2
Buffalo Bills BUF
Season stats rank
Total Yards 427.5 2
Passing Yards 283 4
Rushing Yards 144.5 6
Points Scored 38.5 1
Field Goal % 1 1

Injuries

Carolina Panthers CAR
Buffalo Bills BUF

Carolina vs. Buffalo Betting News

Carolina Panthers CAR

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Buffalo Bills BUF

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Carolina Vs Buffalo Betting Trends

Carolina Panthers CAR

Over is 5-2-1 in Panthers last 8 Saturday games.

Panthers are 4-1 ATS in their last 5 games as a road underdog.

Panthers are 34-16-2 ATS in their last 52 games as an underdog of 0.5-3.0.

Over is 14-4 in Panthers last 18 games as an underdog of 3.5-10.0.

Over is 48-20 in Panthers last 68 games as a road underdog of 3.5-10.0.

Buffalo Bills BUF

Under is 4-1 in Bills last 5 games as a home underdog of 3.5-10.0.

Bills are 4-1 ATS in their last 5 games as a home underdog of 0.5-3.0.

Over is 4-0 in Bills last 4 games as a home favorite of 10.5 or greater.

Over is 13-3 in Bills last 16 Saturday games.

Over is 4-1 in Bills last 5 games as a favorite.

National Football Conference Standings

American Football Conference Standings

Line Up - Last Game

Carolina Panthers
Pitchers
POS Player
Hitters
POS Player
Buffalo Bills
Pitchers
POS Player
Hitters
POS Player