Cleveland Guardians vs. Toronto Blue Jays: Odds, Prediction

Payton Matthews | Updated Aug 11, 2022

Off a disappointing road trip, the Blue Jays return home for a six-game homestand starting Friday against AL Central leader Cleveland.

August 12, 2022, 7:07 PM ET
Rogers Centre
Runline +1.5 -136
Moneyline +142
Over / Under o +8.5


Betting Action


Runline -1.5 +113
Moneyline -170
Over / Under u +8.5


Betting Action


Toronto is a -190 favourite for the opener on the MLB odds.

Guardians vs. Jays Aug 12 Betting Analysis

This is the fourth straight series the Blue Jays will play against a potential American League playoff team following trips to Tampa Bay, Minnesota and Baltimore. The Guardians are battling the Twins for the AL Central title and also in the Wild-Card mix.

In early May, the Blue Jays lost three of four in Cleveland. Toronto hit just .208 in the series with two homers. Santiago Espinal was 5-for-12 with three doubles. Alejandro Kirk and Vladimir Guerrero Jr. were both 4-for-14 with a homer and two RBIs. Matt Chapman was 1-for-14 with six strikeouts. Cleveland hit .289 in the series with three homers. Franmil Reyes was 9-for-14 with a homer and three RBIs, but he was released not long ago and is now with the Cubs. Owen Miller was 4-for-10 with a homer and five RBIs. Kwan was 4-for-15 with a homer, four RBIs and four runs scored.

Toronto won three of four at home vs. Cleveland (then still the Indians) last season.

Cleveland Guardians

Apparently, just one player will not make the trip to Toronto because of COVID vaccination status: Right-hander reliever James Karinchak. Cleveland has a terrific bullpen, and he’s a big part of it with a 1.72 ERA. The team is pretty healthy otherwise. The Guardians have one of the better rookies in the AL in outfielder Steven Kwan, although he’s not going to win Rookie of the Year honours. All-Star third baseman Jose Ramirez is among the AL RBI leaders but not likely to catch the Yankees’ Aaron Judge for that title. It’s right-hander and Port Hope, Ontario native Cal Quantrill (8-5, 3.88 ERA) scheduled on the mound Friday. He was acquired in trade late in the 2020 season from San Diego in the deal that sent starting pitcher Mike Clevinger to the Padres. Quantrill is 6-0 with a 3.16 ERA at home and 2-5 with a 4.96 ERA away. He didn’t face Toronto in the first series. Whit Merrifield is 1-for-16 off Quantrill. The Guardians are 6-2 in their past eight series openers.

Toronto Blue Jays

Toronto got an unplanned two straight days off this week when Wednesday’s game in Baltimore was rained out ahead of a scheduled off day Thursday – the teams couldn’t make up the game on Thursday because the Orioles had to play in Boston. The game has been rescheduled as part of a doubleheader on Sept. 5. Toronto will at least have its full bullpen available Friday with the mini-break. The rainout has affected the rotation as now Jose Berrios will start Friday instead of Mitch White (Saturday). That works out well as Berrios (8-4, 5.19 ERA) is 6-0 with a 3.23 ERA at home compared to 2-4 with a 7.50 ERA on the road. The right-hander was not good in Cleveland on May 5, allowing six runs over 4.2 innings. Jose Ramirez has seen him the most career of any Guardians player and is 8-for-42 with two doubles and a homer. The Blue Jays are 5-1 in their past six series openers.

MLB Prediction: Who Will Win Guardians vs. Blue Jays?