Toronto Blue Jays vs. Tampa Bay Rays: Odds, Prediction

Payton Matthews | Updated Sep 22, 2022

It’s the penultimate road series of the 2022 season for the Blue Jays starting Thursday night as they visit the Tampa Bay Rays in a possible playoff preview.

September 22, 2022, 6:40 PM ET
Tropicana Field
Tampa Bay
Runline -1.5 +134
Moneyline -130
Over / Under o +7.5


Betting Action


Runline +1.5 -161
Moneyline +108
Over / Under u +7.5


Betting Action


Toronto is a -125 favourite on the MLB odds.

Jays vs Rays Sept 22nd Betting Analysis

One last reminder of how the next expanded playoff field works in each league: The top two seeds each get a bye to the divisional series. That will be Houston and the New York Yankees in the American League. The third seed is the division winner with the worst record and that will be Cleveland in the Central. It would host the Wild-Card team with the worst record in the Wild-Card series, and the WC team with the best record hosts the No. 2 WC team in the other.

Thus, it’s very possible the Blue Jays and Rays face off in that Wild-Card series. Toronto is in the pole position for that top Wild-Card spot and the second will come down to most likely Tampa Bay or Seattle (Baltimore is four games back of the No. 3 spot and not dead yet).

Tampa Bay leads the season series 8-7 and is 3-2 at home. Lourdes Gurriel Jr. is batting .353 vs. Tampa Bay pitching, Santiago Espinal .333 and Vladimir Guerrero Jr. .281 with two homers and 10 RBIs. Matt Chapman is almost impossibly 4-for-46 with 15 strikeouts in the series. Tampa’s Yandy Diaz is hitting .390 with two homers and six RBIs vs. Toronto.

Toronto Blue Jays

Toronto suffered a tough loss Wednesday, blowing a 3-0 eighth-inning lead in Philadelphia and falling 4-3 in 10 innings. All three Jays runs came on the 30th homer of the season from Vladimir Guerrero Jr. Santiago Espinal was removed from the game due to discomfort in his left side and replaced at second base by Cavan Biggio. Jose Berrios (11-5, 4.99 ERA) is scheduled on the mound Thursday for Toronto, which probably would like to avoid starting him on the road if possible as the right-hander is 4-4 with a 6.19 ERA and .303 opponents’ batting average away compared to 7-1 with a 3.98 ERA at home. Berrios is 1-0 with a 2.38 ERA in two starts this year vs. the Rays, both at Rogers Centre. Ji-Man Choi is 4-for-14 career off him with a homer and double. Former AL Rookie of the Year Randy Arozarena is 2-for-6. Toronto is 7-0 in its past seven after a loss.

Tampa Bay Rays

The Rays ran into a Houston buzzsaw to start this week as Tampa Bay was swept three at home by the Astros and managed only two runs – both in Wednesday’s 5-2 loss. It was Houston’s first-ever sweep at Tropicana Field. There are reports that two of the team’s best players, Yandy Diaz and Randy Arozarena, got into a fight Monday in the Tropicana Field parking lot. Neither played Tuesday, but Arozarena did Wednesday. Diaz was held out again with left shoulder soreness, and it’s not clear if that’s from the fight. Tampa Bay created the concept of using an opener and will do so here with JT Chargois (2-0, 2.76 ERA), but the bulk pitcher should be lefty Ryan Yarbrough (2-8, 4.33 ERA). He is 0-1 with a 4.15 ERA in 13 innings this year vs. Toronto. Teoscar Hernandez kills him, going 12-for-33 with six homers and two doubles. Tampa Bay is 1-5 in its past six vs. teams with a winning record.

MLB Prediction: Who Will Win Blue Jays vs. Rays?