This matchup features the largest point spread of the season, with the 2-0 Roughriders opening and staying as double-digit favourites to win at home on the CFL odds. The 1-0 Redblacks have shocked the CFL world already in Week 1, and will have another opportunity to do so in Regina.

Kickoff at Mosaic Stadium is scheduled for 7 p.m. EST.

CFL Odds and Betting

Saskatchewan comes in winners of five of their last six games, while Ottawa’s dropped 15 of their last 17. The Redblacks have only managed to cover the spread in two of their last 11 chances, whereas the Riders are rolling on that perspective, with a 6-2-1 ATS record over their last nine games.

Head-to-head, these teams have split their last 10 games with the over hitting in eight of those contests. Ottawa’s averaged 307 passing yards in those games, but it’s pretty safe to say they won’t be hitting anywhere near that Saturday after a 71-yard passing performance in Week 1.

Ottawa RedBlacks

Ottawa is 1-0, says the CFL standings. But let’s not dismiss the Redblacks putting up 127 yards of offence in their lone game, and surrendering almost 450. Ottawa looked as outmatched in Week 1 as many expected but were literally handed…I mean found a way to get the two points.

Matt Nichols did what he’s done throughout his CFL career — win games — but a 12-of-20, 71-yard outing won’t win you many CFL games. Nichols found some chemistry with rookie Ryan Davis in the win, who had six catches for 33 yards to lead all receivers. On defence in Week 1, middle linebacker Avery Williams was a force with 14 tackles and a sack, while Abdul Kanneh snatched two interceptions including the game-winning pick-six, also the game’s only touchdown.

Saskatchewan Roughriders

The CFL is back to normal when it’s tough to win at Saskatchewan. The Riders are 9-1 in their last 10 at homes and have played six phenomenal quarters of football in 2021, the other two featuring all kinds of fluke plays against them. They look like one of the few CFL teams with their game together, which is why Saturday night’s the first double-digit spread of the season and it’s in Saskatchewan’s favour.

The Riders will be without No. 1 receiver Shaq Evans (ankle) though, who is on the six-game injured list. Kyran Moore is a strong candidate to replace Evans’ production after putting up 10 receptions for 110 yards and two touchdowns in Saskatchewan’s first two games.

On the defensive side, A.C. Leonard has been everywhere with six tackles, two sacks, an interception, and a fumble recovery in two games.

CFL Prediction: Who Will Win RedBlacks vs. Roughriders?