Texans vs. Colts Point Spread: NFL Week 6 Odds, Prediction

Jordan Ramsay | Updated Oct 14, 2021

Can the Colts start to gain back ground in the AFC South when they host Houston on Sunday?

October 17, 2021, 1:00 PM ET
Lucas Oil Stadium
Pointspread +11.5 -105
Moneyline +410
Over / Under o +45


Betting Action


Pointspread -11.5 -114
Moneyline -511
Over / Under u +45


Betting Action


After stumbling in Baltimore on Monday night, the Indianapolis Colts will look to get things back on track when they host the division rival Houston Texans Sunday afternoon.  Indy will likely come into this game motivated after blowing a 25-9 fourth quarter lead and losing to the Ravens in overtime.  Houston, on the other hand, continued their train wreck of a season last week, dropping a 25-22 decision to New England for their fourth straight loss.

The Colts are heavy 10-point favourites to win on the NFL odds, with a total of 43.5.

NFL Point Spread and Betting Analysis

Indianapolis took both meetings against Houston last year, winning 26-20 at home and 27-20 on the road.  Sports Interaction bettors seem to be banking on the Texans covering that high number, as 61 per cent of early action is taking Houston.  The Over is receiving well over 80 per cent of bets, although the last three games between these teams have actually gone Under.

It’s going to be no easy task to turn this Houston team around.  The Texans have lost nine of their last 10 games dating back to last season and they’ve dropped 16 of their last 19 games in Indianapolis.  They’re 3-2 against the spread for the season, but have failed to cover in five of their last six games against the Colts.  The total has gone Over in three of Houston’s game this season.  Four of the Texans’ last six divisional games have gone Over.

Indy has been successful against Houston, going 5-1 straight up and ATS in their last six games against the Texans.  The total has gone Over in 12 of the Colts’ last 18 overall, including three times this season.  They’re 3-2 ATS for the year, but have failed to cover in four of their last five home games.

Houston Texans

It looked like Houston was in line for an upset win last week, as they held a 22-9 lead early in the third quarter.  That would be as far as they would get, though.  The Texans allowed 16 unanswered points in the second half and dropped their fourth straight game.  Rookie quarterback Davis Mills, however, looked better.  Mills was 21-for-29, throwing for a career-high 312 yards and three touchdowns.  It was a bounce-back performance with no picks, a week after throwing a franchise-record four interceptions.  Receiver Chris Moore also had a breakout game after being promoted from the practice squad.  Moore finished with a game-high 109 yards and a touchdown on five receptions.

Left tackle Laremy Tunsil was forced out of the game in the third quarter with a thumb injury.  Tunsil is set to undergo surgery to repair a torn ligament and will miss about four weeks.  There’s still be no update on veteran quarterback Tyrod Taylor‘s status, although he’s not expected to play this week.  Taylor hasn’t played since suffering a hamstring injury in Week 2.

Indianapolis Colts

The Colts had an absolute meltdown last week against the Ravens.  Indy had a 22-3 lead on the road in Baltimore at one point, before losing the game in overtime.  The Colts had a chance to avoid the extra period, but Rodrigo Blakenship missed a 47-yard field goal on the final play of regulation.  Blakenship had previously hurt his hip in warmup and it’s unclear if he’ll be able to play against Houston.  Carson Wentz looked good last week after dealing with two sprained ankles early in the season.  Wentz was 25-for-35 and finished with a career-high 402 passing yards.  He threw for two touchdowns and no interceptions.

Indianapolis’ secondary took a bit of a hit last week.  Cornerback Xavier Rhodes and safety Andrew Sendejo are both in concussion protocol.  The status of both players is unclear.  They each need to pass through five stages of concussion protocol, which will be made more difficult by the shorter week.

NFL Prediction: Who Will Win Texans vs. Colts?