The Cardinals are the NFL's only undefeated team (6-0) and are also 5-1 against the spread this spread.
There are big spreads – and then there’s the massive odds chasm between the Houston Texans and Arizona Cardinals, who square off Sunday afternoon in Glendale. The Cardinals are favoured by more than two touchdowns as they look to remain the lone unbeaten team in the NFL – and those looking for massive payday in Week 7 action might consider an outright play on the underdog Texans, though that’s a bold call given their road struggles in 2021.
NFL Point Spread and Betting Analysis
This is easily the biggest spread of the NFL season to date – and the most points the Cardinals have been favoured in franchise history. And despite the massive gap, 62 percent of the Sports Interaction betting public is siding with the unbeaten hosts. You have to lower the spread to seven or more points to get a recent sample relevant to this team – and Arizona has gone a perfect 3-0 SU and ATS in three games at -7 or better since 2020.
The totals trends are nearly identical, with 61 percent of SIA bettors siding with the O47.5 at -110. The Cardinals have converted the Under in all three games they’ve played as a fave of 7+ points, but have been a much stronger Over play overall, having gone 6-2 ATS in their last eight games at State Farm Stadium. Houston has gone below the total in two of three road games this season – and I’ll get into why in the very next section.
Houston Texans
The Texans have played the charitable visitors to near-perfection so far this season, giving other teams’ home fans plenty of reason to celebrate. Houston comes into Week 7 having not only lost all three games away from NRG Stadium, they’ve been outscored by a ridiculous 102-24 margin – including a 71-3 gap in consecutive losses at Buffalo and Indianapolis. Houston has dropped five straight road games dating back to 2020.
Arizona Cardinals
Looking for value outside of the spread or total? It’s a bit tougher when one team is favoured by so much – but there are potential value pockets here. Arizona is averaging 7.5 first-quarter points per game, second-most in the NFL behind only Dallas. Houston, on the other hand, is allowing 7.0 first-quarter points per contest on the road. Bettors might want to consider loading up on the “Quarter of First Touchdown: 1st” prop, which pays -345.
Who Will Win Texans vs. Cardinals?
Line History
Sports Interaction customers are placing their bets on:
time | fav | line | total |
---|---|---|---|
Opening 12 Oct 8:34pm | HOU | -14.5 -110 | O +49.5 -110 |
Closing 24 Oct 4:11pm | HOU | -20 -110 | O +47.5 -113 |
- Regular Season
- Playoffs
Texans Team Leaders
Touchdowns |
6 |
Rushing |
427 |
Passing |
2664 |
Receiving |
90 |
Sacks |
8 |
Interceptions |
3 |
Touchdowns |
18 |
Rushing |
752 |
Passing |
3787 |
Receiving |
77 |
Sacks |
11 |
Interceptions |
4 |
Touchdowns | |
Rushing | |
Passing | Did not qualify |
Receiving | |
Sacks | |
Interceptions |
Touchdowns |
1 |
Rushing |
28 |
Passing |
137 |
Receiving |
6 |
Sacks |
1 |
Interceptions |
0 |
- Regular Season
- Playoffs
Cardinals Team Leaders
Touchdowns |
6 |
Rushing |
427 |
Passing |
2664 |
Receiving |
90 |
Sacks |
8 |
Interceptions |
3 |
Touchdowns |
18 |
Rushing |
752 |
Passing |
3787 |
Receiving |
77 |
Sacks |
11 |
Interceptions |
4 |
Touchdowns | |
Rushing | |
Passing | Did not qualify |
Receiving | |
Sacks | |
Interceptions |
Touchdowns |
1 |
Rushing |
28 |
Passing |
137 |
Receiving |
6 |
Sacks |
1 |
Interceptions |
0 |
Weather

condition | dome |
Injuries
Jordan Akins (TE)
Chris Conley (WR)
Kamu Grugier-Hill (LB)
Justin Britt (OL)
Jonathan Greenard (DL)
Jonathan Owens (DB)
Justin Reid (DB)
Grayland Arnold (DB)
Kevin Pierre-Louis (LB)
Antony Auclair (TE)
Greg Mabin (CB)
Zach Allen (DE)
Justin Pugh (OL)
Isaiah Simmons (LB)
Antonio Hamilton (CB)
Jonathan Ward (RB)
Zach Allen (DE)
Chase Edmonds (RB)
Dennis Gardeck (LB)
Tanner Vallejo (LB)
Injuries
player (position) | status | ats*current | o/u* | notes | |
---|---|---|---|---|---|
Jordan Akins (TE) | Out Sun | Illness - 06 / 01 / 22 | 0-1 | 0-1 | + - |
Akins is nursing an illness, and he will not be active for Sunday's matchup with the Titans. |
|||||
Chris Conley (WR) | Out Sun | Knee - 05 / 01 / 22 | 0-1 | 0-1 | + - |
Conley is nursing a knee issue, and he will not partake in Sunday's matchup with the Titans. |
|||||
Kamu Grugier-Hill (LB) | Prob Sun | Knee - 05 / 01 / 22 | 0-1 | 0-1 | + - |
Grigier-Hill has a knee injury, but it is anticipated that he will partake in Sunday's showdown with the Titans. |
|||||
Justin Britt (OL) | Prob Sun | Knee - 05 / 01 / 22 | 0-1 | 0-1 | + - |
Britt has a knee injury, but it is projected that he will lace up against the Titans on Sunday. |
|||||
Jonathan Greenard (DL) | day-to-day | Foot - 03 / 01 / 22 | 0-1 | 0-1 | + - |
Greenard exited Sunday's tilt against the Titans with a foot injury, and he will not return. |
|||||
Jonathan Owens (DB) | I-R | Wrist - 03 / 01 / 22 | 0-1 | 0-1 | + - |
Owens has ended up on the injured reserve list due to a wrist injury. |
|||||
Justin Reid (DB) | Out indefinitely | Ankle - 03 / 01 / 22 | 0-1 | 0-1 | + - |
Reid is dealing with injuries to his ankle and knee. He has also been assigned to the IR/COVID-19 list, and it has yet to be established when he will be available. |
|||||
Grayland Arnold (DB) | I-R | Ankle - 03 / 01 / 22 | 0-1 | 0-1 | + - |
Arnold has landed on the injured reserve list with an ankle injury. |
|||||
Kevin Pierre-Louis (LB) | Out indefinitely | Illness - 31 / 12 / 21 | 1-1 | 1-1 | + - |
Pierre-Louis has been shifted to the IR/COVID-19 list, and it is unknown when he will return. |
|||||
Antony Auclair (TE) | Out indefinitely | Illness - 30 / 12 / 21 | 1-1 | 1-1 | + - |
Auclair has been assigned to the IR/COVID-19 list, and it is unclear when he will return. |
player (position) | status | ats*current | o/u* | notes | |
---|---|---|---|---|---|
Greg Mabin (CB) | Out indefinitely | Illness - 19 / 01 / 22 | 0-0 | 0-0 | + - |
Mabin has been added to the IR/COVID-19 list, and there is no timetable for return. |
|||||
Zach Allen (DE) | Prob Mon | Ankle - 14 / 01 / 22 | 0-1 | 1-0 | + - |
Allen has an ankle injury, but it is projected that he will take on the Rams in the NFC wild-card game. |
|||||
Justin Pugh (OL) | Ques Mon | Calf - 14 / 01 / 22 | 0-1 | 1-0 | + - |
Pugh is hobbled by a calf ailment, and it is undetermined if he will line up for the NFC wild-card game versus the Rams. |
|||||
Isaiah Simmons (LB) | Ques Mon | Personal - 14 / 01 / 22 | 0-1 | 1-0 | + - |
Simmons is tending to a personal matter, and it is unclear if he will be active for the NFC wild-card battle against the Rams. |
|||||
Antonio Hamilton (CB) | Prob Mon | Teeth - 14 / 01 / 22 | 0-1 | 1-0 | + - |
Hamilton is battling a tooth issue, but it is anticipated that he will face the Rams in the NFC wild-card game. |
|||||
Jonathan Ward (RB) | Ques Mon | Knee - 12 / 01 / 22 | 0-1 | 1-0 | + - |
Ward is managing a knee injury, and it is undecided if he will suit up for the NFC wild-card game against the Rams. |
|||||
Zach Allen (DE) | Ques Sun | Ankle - 06 / 01 / 22 | 1-1 | 1-1 | + - |
Allen is bothered by an ankle injury, and it is uncertain if he will take on the Seahawks on Sunday. |
|||||
Chase Edmonds (RB) | Prob Mon | Ribs - 06 / 01 / 22 | 1-1 | 1-1 | + - |
Edmonds has injuries to his ribs and toe, but it is anticipated that he will take the field against the Rams for the NFC wild-card game. |
|||||
Dennis Gardeck (LB) | Ques Sun | Thumb - 06 / 01 / 22 | 1-1 | 1-1 | + - |
Gardeck is hindered by a thumb injury, and it is unclear if he will partake in Sunday's contest against the Seahawks. |
|||||
Tanner Vallejo (LB) | Out indefinitely | Illness - 04 / 01 / 22 | 1-1 | 1-1 | + - |
Vallejo has been added to the IR/COVID-19 list, and it has yet to be decided when he will return to action. |
-
HOUSTON TEXANS
10 -
ARIZONA CARDINALS
34
Score
Prediction
-
Line History
Sports Interaction customers are placing their bets on:
time fav line total Opening 12 Oct 8:34pm HOU -14.5 -110 O +49.5 -110 Closing 24 Oct 4:11pm HOU -20 -110 O +47.5 -113 -
- Regular Season
- Playoffs
Texans Team Leaders
Touchdowns 6
Rushing 427
Passing 2664
Receiving 90
Sacks 8
Interceptions 3
Touchdowns 18
Rushing 752
Passing 3787
Receiving 77
Sacks 11
Interceptions 4
Touchdowns Rushing Passing Did not qualify Receiving Sacks Interceptions Touchdowns 1
Rushing 28
Passing 137
Receiving 6
Sacks 1
Interceptions 0
-
- Regular Season
- Playoffs
Cardinals Team Leaders
Touchdowns 6
Rushing 427
Passing 2664
Receiving 90
Sacks 8
Interceptions 3
Touchdowns 18
Rushing 752
Passing 3787
Receiving 77
Sacks 11
Interceptions 4
Touchdowns Rushing Passing Did not qualify Receiving Sacks Interceptions Touchdowns 1
Rushing 28
Passing 137
Receiving 6
Sacks 1
Interceptions 0
-
Weather
condition dome -
Injuries
Jordan Akins (TE)
Out Sun Illness - 06 / 01 / 22Chris Conley (WR)
Out Sun Knee - 05 / 01 / 22Kamu Grugier-Hill (LB)
Prob Sun Knee - 05 / 01 / 22Justin Britt (OL)
Prob Sun Knee - 05 / 01 / 22Jonathan Greenard (DL)
day-to-day Foot - 03 / 01 / 22Jonathan Owens (DB)
I-R Wrist - 03 / 01 / 22Justin Reid (DB)
Out indefinitely Ankle - 03 / 01 / 22Grayland Arnold (DB)
I-R Ankle - 03 / 01 / 22Kevin Pierre-Louis (LB)
Out indefinitely Illness - 31 / 12 / 21Antony Auclair (TE)
Out indefinitely Illness - 30 / 12 / 21Greg Mabin (CB)
Out indefinitely Illness - 19 / 01 / 22Zach Allen (DE)
Prob Mon Ankle - 14 / 01 / 22Justin Pugh (OL)
Ques Mon Calf - 14 / 01 / 22Isaiah Simmons (LB)
Ques Mon Personal - 14 / 01 / 22Antonio Hamilton (CB)
Prob Mon Teeth - 14 / 01 / 22Jonathan Ward (RB)
Ques Mon Knee - 12 / 01 / 22Zach Allen (DE)
Ques Sun Ankle - 06 / 01 / 22Chase Edmonds (RB)
Prob Mon Ribs - 06 / 01 / 22Dennis Gardeck (LB)
Ques Sun Thumb - 06 / 01 / 22Tanner Vallejo (LB)
Out indefinitely Illness - 04 / 01 / 22Injuries
player (position) status ats*current o/u* notes Jordan Akins (TE) Out Sun Illness - 06 / 01 / 22 0-1 0-1 + - Akins is nursing an illness, and he will not be active for Sunday's matchup with the Titans.
Chris Conley (WR) Out Sun Knee - 05 / 01 / 22 0-1 0-1 + - Conley is nursing a knee issue, and he will not partake in Sunday's matchup with the Titans.
Kamu Grugier-Hill (LB) Prob Sun Knee - 05 / 01 / 22 0-1 0-1 + - Grigier-Hill has a knee injury, but it is anticipated that he will partake in Sunday's showdown with the Titans.
Justin Britt (OL) Prob Sun Knee - 05 / 01 / 22 0-1 0-1 + - Britt has a knee injury, but it is projected that he will lace up against the Titans on Sunday.
Jonathan Greenard (DL) day-to-day Foot - 03 / 01 / 22 0-1 0-1 + - Greenard exited Sunday's tilt against the Titans with a foot injury, and he will not return.
Jonathan Owens (DB) I-R Wrist - 03 / 01 / 22 0-1 0-1 + - Owens has ended up on the injured reserve list due to a wrist injury.
Justin Reid (DB) Out indefinitely Ankle - 03 / 01 / 22 0-1 0-1 + - Reid is dealing with injuries to his ankle and knee. He has also been assigned to the IR/COVID-19 list, and it has yet to be established when he will be available.
Grayland Arnold (DB) I-R Ankle - 03 / 01 / 22 0-1 0-1 + - Arnold has landed on the injured reserve list with an ankle injury.
Kevin Pierre-Louis (LB) Out indefinitely Illness - 31 / 12 / 21 1-1 1-1 + - Pierre-Louis has been shifted to the IR/COVID-19 list, and it is unknown when he will return.
Antony Auclair (TE) Out indefinitely Illness - 30 / 12 / 21 1-1 1-1 + - Auclair has been assigned to the IR/COVID-19 list, and it is unclear when he will return.
player (position) status ats*current o/u* notes Greg Mabin (CB) Out indefinitely Illness - 19 / 01 / 22 0-0 0-0 + - Mabin has been added to the IR/COVID-19 list, and there is no timetable for return.
Zach Allen (DE) Prob Mon Ankle - 14 / 01 / 22 0-1 1-0 + - Allen has an ankle injury, but it is projected that he will take on the Rams in the NFC wild-card game.
Justin Pugh (OL) Ques Mon Calf - 14 / 01 / 22 0-1 1-0 + - Pugh is hobbled by a calf ailment, and it is undetermined if he will line up for the NFC wild-card game versus the Rams.
Isaiah Simmons (LB) Ques Mon Personal - 14 / 01 / 22 0-1 1-0 + - Simmons is tending to a personal matter, and it is unclear if he will be active for the NFC wild-card battle against the Rams.
Antonio Hamilton (CB) Prob Mon Teeth - 14 / 01 / 22 0-1 1-0 + - Hamilton is battling a tooth issue, but it is anticipated that he will face the Rams in the NFC wild-card game.
Jonathan Ward (RB) Ques Mon Knee - 12 / 01 / 22 0-1 1-0 + - Ward is managing a knee injury, and it is undecided if he will suit up for the NFC wild-card game against the Rams.
Zach Allen (DE) Ques Sun Ankle - 06 / 01 / 22 1-1 1-1 + - Allen is bothered by an ankle injury, and it is uncertain if he will take on the Seahawks on Sunday.
Chase Edmonds (RB) Prob Mon Ribs - 06 / 01 / 22 1-1 1-1 + - Edmonds has injuries to his ribs and toe, but it is anticipated that he will take the field against the Rams for the NFC wild-card game.
Dennis Gardeck (LB) Ques Sun Thumb - 06 / 01 / 22 1-1 1-1 + - Gardeck is hindered by a thumb injury, and it is unclear if he will partake in Sunday's contest against the Seahawks.
Tanner Vallejo (LB) Out indefinitely Illness - 04 / 01 / 22 1-1 1-1 + - Vallejo has been added to the IR/COVID-19 list, and it has yet to be decided when he will return to action.