Rams vs. Vikings Point Spread: NFL Week 16 Odds, Prediction

Daniel Coyle | Updated Dec 23, 2021

The Minnesota Vikings look to strengthen their tenuous grip on an NFC wild card spot when they play host to the Los Angeles Rams on Sunday in NFL Week 16 action.

L.A. Rams
December 26, 2021, 1:00 PM ET
U.S. Bank Stadium
Pointspread -3.5 -103
Moneyline -192
Over / Under o +48.5


Betting Action


Pointspread +3.5 -117
Moneyline +158
Over / Under u +48.5


Betting Action


The Vikings extended their current straight up win streak to two games with last weekend’s 17-9 win Chicago. The Rams return to action on just four days rest after extending their current win streak to three games with Tuesday’s 20-10 victory over the visiting Seattle Seahawks.

L.A. is a 3-point favourite to win on the NFL odds, with a total of 49.0.

NFL Point Spread and Betting Analysis

Backed by 77 per cent of sports bettors, the Rams have held steady since opening as 3-point road favourites. The total has dipped slightly since opening at 49.5, sliding to 49, with a narrow majority of 52 per cent of the betting action supporting the UNDER.

Sunday afternoon’s matchup at US Bank Stadium marks the first meeting between these NFC rivals since September 2018. The Rams powered to a narrow 38-31 win as 7-point home chalk in that contest. However, the Vikings have otherwise dominated in head-to-head action, claiming outright and against the spread win in each of their five previous meetings. The Vikings have also produced steady results when facing the Rams on home turf, going 6-1 straight up in seven home dates since 1987, and covering in three of their past four.

While the UNDER has paid out in three of the past four dates involving these teams, offensive explosions by Minnesota have not been uncommon. The Vikings have averaged over 30 points per game in their six against LA. Conversely, the Rams averaged just 12.6 points per game in their recent five-game losing streak against Minnesota.

Los Angeles Rams

The Rams have lifted themselves back into contention for the NFC West crown and the top seed in the conference with their current three-game win streak. And the team’s two NFL MVP candidates have played a huge role in that success. Quarterback Matthew Stafford’s two touchdown passes to receiver Cooper Kupp proved to be the difference in Tuesday’s victory. Stafford has now connected on 11 scoring tosses over his past four outings, with Kupp being on the receiving end of four TD passes over the past three weeks. Of course, the steady play of the Rams defence cannot be overlooked. LA has surrendered just 13.3 points per game during their current 3-0 run after allowing 31.7 points per game during a preceding three-game slide.

Minnesota Vikings

Injuries have emerged as a major concern for the Vikings ahead of yet another must-win contest. Quarterback Kirk Cousins was sacked four times in last week’s win over the Bears, and was limited at Wednesday practice with a rib injury. Cousins has been far from dominant in his past two outings, and compiled just 87 passing yards in Chicago. He still managed to connect on two scoring passes and has tossed for multiple TDs in eight of his past nine outings. The good news for the Vikings is that receiver Adam Thielen is on the mend. Thielen has not seen action since Week 13 while recovering from an ankle injury, but was a limited participant at Wednesday practice, and has been vocal about his intent to play on Sunday.

NFL Prediction: Who Will Win Rams vs. Vikings?