Rams vs. Giants Point Spread: NFL Week 6 Odds, Prediction

Jordan Ramsay | Updated Oct 14, 2021

Can the L.A. Rams pick up a second straight road victory when they face the banged up New York Giants Sunday afternoon?

L.A. Rams
October 17, 2021, 1:00 PM ET
MetLife Stadium
Pointspread -8 -115
Moneyline -397
Over / Under o +49


Betting Action


Pointspread +8 -105
Moneyline +323
Over / Under u +49


Betting Action


The 4-1 L.A. Rams are riding high after a key 26-17 divisional win in Seattle last week.  The 1-4 New York Giants, on the other hand, are limping into this contest, figuratively and literally, after dropping a 44-20 decision in Dallas.

Los Angeles is a huge 9.5-point favourite to win on the NFL odds, with a total of 49.0.

NFL Point Spread and Betting Analysis

These teams met once last season, a Week 4 matchup in L.A.  The Rams came out with a 17-9 win, with Jared Goff (now in Detroit) throwing for 200 yards and a touchdown.  Daniel Jones led the Giants, finishing with 190 passing yards, no touchdowns and an interception.  Los Angeles is receiving an overwhelming 90 per cent of the early betting action, while the Under is favoured at 70 per cent.  Two of the last three games between these teams have gone Under.

Despite how heavily favoured the Rams are in this game, they’ve actually struggled against New York.  L.A. has lost seven of their last nine games against the Giants and only covered in one of those meetings.  They’re 4-1 against the spread this season.  High numbers have been a staple for the Rams.  The total has gone Over in six of L.A.’s last seven games overall, including four of five games this season.

The Giants have had success against L.A., but they’ve struggled against the NFC West in general.  New York has lost eight of their last 10 games against NFC West opponents.  They also haven’t had great results in the fall, as they’ve lost 13 of their last 15 games in the month of October.  The Giants are 3-6 ATS in their last nine games, including 2-3 ATS this season.  The total has gone Over in four of New York’s last five home games against L.A. and three of their five games this season.

Los Angeles Rams

With Arizona the only undefeated team left in the NFL, it was huge for L.A. to pick up a win in Seattle last week.  Matthew Stafford was 25-for-37, finishing with 365 passing yards, a touchdown and an interception.  There was concern when Stafford appeared to injure his finger sometime in the second quarter, although he didn’t miss any plays and is expected to be ready on Sunday.  Robert Woods and Cooper Kupp continued to pad their fantasy stats.  Woods finished with a game-high 150 receiving yards, while Kupp added 92.  Darrell Henderson Jr. is also a viable fantasy option.  Henderson has rushed for over 80 yards in two straight games and he’ll be facing a Giants rushing defence that ranks sixth-worst in the league, allowing 138.4 rushing yards per game.

New York Giants

If the Giants could go back in time, they’d likely just forfeit last week’s game and save themselves the injury headaches.  Jones (5-for-13, 98 passing yards) suffered a concussion, Saquon Barkley and Kadarius Toney suffered ankle injuries and Kenny Golladay is dealing with a knee injury.  Jones, Toney and Sterling Shepard, who has missed the last two games with a hamstring injury, are all listed as questionable for Sunday.  Barkley and Golladay have both been ruled out.  If Jones isn’t ready to play, Mike Glennon will take over under centre.  Glennon replaced Jones last week, going 16-for-25 and finishing with 196 passing yards, a touchdown and two interceptions.

NFL Prediction: Who Will Win Rams vs. Giants?