Patriots vs. Colts Point Spread: NFL Week 15 Odds, Prediction

Jordan Ramsay | Updated Dec 16, 2021

Jonathan Taylor has established himself as one of the NFL's elite running backs. Taylor's 16 rushing TDs ties the Colts' franchise record and he has made it into the end zone in 10 straight games.

December 18, 2021, 8:15 PM ET
Lucas Oil Stadium
Pointspread 0 -110
Moneyline -105
Over / Under o +46.5


Betting Action


Pointspread 0 -110
Moneyline -115
Over / Under u +46.5


Betting Action


It’s a potential playoff preview in the AFC when the New England Patriots travel to Indianapolis to face the Colts on Saturday.  Both teams are coming off Week 14 byes.  New England downed the Bills 14-10 in Week 13 with a bizarre strategy that saw the Pats throw the ball just three times.  The Colts are also coming off a Week 13 win that saw saw them shut out the Texans 31-0.

Indy is a 2-point favourite to win on the NFL odds, with a total of 45.5.

NFL Point Spread and Betting Analysis

The Patriots have absolutely dominated this head-to-head series, winning the last eight games, although that was with Tom Brady under centre.  The series has been historically high scoring, with the Over hitting in the last nine games.  Sports Interaction bettors are banking on both streaks continuing as 58 per cent of action is taking the Pats, while 67 per cent of bettors are taking the Over.

Bill Belichick has cemented himself as a -104 favourite to win Coach of the Year this season.  Belichick has led New England to seven straight wins and a perfect 6-0 road record.  They’re 9-4 against the spread overall and have covered in each of their last seven games.  The total has gone Over in six of the Patriots’ last nine games.

Indianapolis has kept their playoff hopes alive with four wins in their last five games.  They’re 8-5 ATS overall and 7-3 ATS in their last 10 games.  The total has gone Over in five of the Colts’ last seven games.

New England Patriots

New England is in a prime position to claim top seed in the AFC and a first-round playoff bye as they sit tied with Kansas City and Tennessee for the conference lead.  They’ll likely need to win-out to claim the AFC’s top seed, but a win next week in Buffalo should at least claim the AFC East.  This team has been all about defence as evidenced by quarterback Mac Jones’ three pass attempts last game.  The Patriots average a league-best 15.4 points allowed per game.  They’ve been even better over their current seven-game win streak, allowing an average of 10.4 ppg.

It was a light work week for Jones in Week 13.  The rookie quarterback completed two of his three pass attempts for 19 yards.  Running backs Damien Harris and Rhamondre Stevenson led the offence.  Harris ran the ball 10 times for 111 yards and a touchdown, while Stevenson picked up 78 yards on 24 carries.  The Patriots out-gained the Bills 222-99 in rushing yards, which could be a big factor in next week’s game.

Indianapolis Colts

The Colts have bounced back from an early season stretch that saw them lose four of their first five games and they now sit in a playoff spot.  The offence has been a major factor in the turnaround, with Indy scoring at least 30 points in seven of their last eight games.  Carson Wentz had a relatively quiet game in the Week 13 win in Houston, passing for 158 yards and a touchdown.  Wentz has had a solid season overall, throwing for 22 touchdowns and just five interceptions.  Running back Jonathan Taylor’s season has been so strong, he has the best odds of any non-QB to win the MVP at +1600.  Taylor leads the NFL in rushing yards (1,348) and rushing touchdowns (16).  He’s had at least one touchdown in 10 straight games.

The Defensive unit has also been strong for the Colts.  Indy has held three of their last four opponents to 17 points or less.  The bye week also gave the defence a chance to let linebacker Darius Leonard (ankle) and tackle DeForest Buckner (knee) rest nagging injuries.

NFL Prediction: Who Will Win Patriots vs. Colts?