NFL Week 11 Predictions: Best Picks Against the Spread

Sports Interaction Staff | Updated Nov 11, 2019

patriots vs eagles

Week 11 is highlighted by a rematch of Super Bowl LII between New England and Philadelphia. There are four teams on the bye: Green Bay, NY Giants, Seattle and Tennessee.

Here’s a quick look at all the Week 11 matchups with Sports Interaction’s NFL odds. Games Sunday unless noted.

Pittsburgh Steelers at Cleveland Browns, Thursday

The Browns almost never were able to beat Steelers QB Ben Roethlisberger, who took particular pride in beating Cleveland because the franchise passed on the Ohio native early in the first round of the 2004 NFL Draft. Well, Big Ben is out for the season – replaced by Mason Rudolph — so perhaps the disappointing Browns can get a rare win in this AFC North rivalry.

Point spread: Browns -2.5

Pick ATS: Cleveland

Dallas Cowboys at Detroit Lions

This spread could change if Lions quarterback Matthew Stafford doesn’t play. He was a surprise scratch Sunday in Chicago with back problems. Stafford had started 136 consecutive regular-season games. Jeff Driskel started in his place and wasn’t very good in a 20-13 loss. The Cowboys were upset Sunday night at home by Minnesota. Dallas rushed for just 50 yards.

Point spread: Cowboys -3.5

Pick ATS: Dallas

Jacksonville Jaguars at Indianapolis Colts

Jacksonville comes off its bye week and Coach Doug Marrone has said he’s benching rookie sensation Gardner Minshew II at quarterback despite a solid 4-4 record under him. Nick Foles, who signed a big off-season free-agent contract with the team but broke his collarbone in Week 1, is ready to return from injury and will start. Not clear if Indy will have starting QB Jacoby Brissett. He missed Sunday’s upset loss to Miami with a knee injury and veteran backup Brian Hoyer was largely terrible in his place.

Point spread: Colts -3

Pick ATS: Indianapolis if Brissett plays

Buffalo Bills at Miami Dolphins

Buffalo goes for the season sweep, although the Bills played terribly for three quarters at home against then-winless Miami in Week 7 before pulling away in the fourth quarter for a 31-21 victory. The Dolphins are ruining their tanking plans with back-to-back victories. Buffalo was a 19-16 loser in Cleveland on Sunday. Stephen Hauschka missed two field goals, including the potential tying kick from 53 yards in the final seconds.

Point spread: Bills -5

Pick ATS: Buffalo

Denver Broncos at Minnesota Vikings

Denver comes out of its bye week and again will go with Brandon Allen at quarterback with Joe Flacco perhaps done for the season due to injury. Allen made his first-ever NFL regular-season appearance and start in Week 9 and led a home upset of Cleveland. The Vikings were upset winners in Dallas on Sunday night. Minnesota had been 0-9-1 in its past 10 games against teams with a winning record.

Point spread: Vikings -10

Pick ATS: Minnesota

New Orleans Saints at Tampa Bay Buccaneers

The Saints were two-touchdown home favourites on Sunday against a Falcons team on a six-game losing streak, but New Orleans was stunned 26-9 to see its six-game winning streak end and ruin a lot of Survivor Pools. The Bucs snapped a four-game skid with a 30-27 win over Arizona. New Orleans goes for the season sweep, beating the Bucs 31-24 in Week 5. Teddy Bridgewater threw for 314 yards and four touchdowns. Michael Thomas was unstoppable with 11 catches for 182 yards and two scores.

Point spread: Saints -5.5

Pick ATS: New Orleans

New York Jets at Washington Redskins

Being honest, one of the least appealing games of the season between teams in a race for the No. 1 overall pick in the 2020 NFL Draft. Washington comes out of its bye week and will start rookie Dwayne Haskins at QB again. He made his first start in Week 9 and threw for just 144 yards in a loss in Buffalo. The Jets actually hurt their chances for the top overall pick by beating the Giants on Sunday.

Point spread: Redskins -1.5

Pick ATS: NY Jets

Atlanta Falcons at Carolina Panthers

Atlanta was easily the biggest upset winner of Week 10, snapping a six-game losing streak with a 26-9 stunner in New Orleans. Matt Ryan returned after missing a game with an ankle injury and had two touchdown passes. Carolina lost 24-16 in Green Bay when Christian McCaffrey was stopped just short of the goal line as time expired. Atlanta swept Carolina last year.

Point spread: Panthers -6

Pick ATS: Carolina

Houston Texans at Baltimore Ravens

Potential playoff preview with both these teams likely to win their respective divisions for a second straight year. Also a matchup of young QBs who are MVP candidates in Houston’s Deshaun Watson and Baltimore’s Lamar Jackson. The Texans are out of their bye, while Baltimore won its fifth in a row Sunday, 49-31 over winless Cincinnati. Jackson was spectacular again with three TD passes and a TD run.

Point spread: Ravens -4

Pick ATS: Baltimore

Arizona Cardinals at San Francisco 49ers

Arizona was a 30-27 loser in Tampa Bay on Sunday despite 324 yards and three touchdowns passing from rookie Kyler Murray. Short week for the Niners as they hosted Seattle in a big game Monday night. These teams played just two weeks ago in the desert and San Francisco escaped 28-25 behind a career game from QB Jimmy Garoppolo.

Point spread: 49ers -13.5 (may change depending on Monday)

Pick ATS: Arizona

Cincinnati Bengals at Oakland Raiders

Oakland won four games all of last season and won its fifth already in 2019 last Thursday, 26-24 over the Chargers. Running back Josh Jacobs burnished his case for NFL Offensive Rookie of the Year honours by scoring game-winning touchdown on an 18-yard run with 1:02 remaining. The winless Bengals came out of their bye and were destroyed at home by Baltimore. In his first NFL start, QB Ryan Finley was 16-for-30 for 167 yards with a touchdown and interception.

Point spread: Raiders -10.5

Pick ATS: Cincinnati

New England Patriots at Philadelphia Eagles

Behind unlikely game MVP Nick Foles (now with the Jaguars), the Eagles upset the Patriots 41-33 in Super Bowl LII two seasons ago; had New England won that, it would be going for an unprecedented three titles in a row this year. Both teams are off their bye for this one.

Point spread: Patriots -3.5

Pick ATS: Philadelphia

Chicago Bears at Los Angeles Rams

Sunday night game. Teams combined for 25 wins last regular season and each won division titles but neither may make the playoffs this year. The Rams came out of their bye Sunday and managed 12 points in a loss in Pittsburgh. Chicago stopped a four-game slide with a home win over Detroit behind three TD passes from embattled QB Mitchell Trubisky. The Bears shut down the Rams in a 15-6 victory in the Windy City late in the 2018 regular season.

Point spread: Rams -6.5

Pick ATS: Los Angeles

Kansas City Chiefs vs. Los Angeles Chargers, Monday

This game is at Estadio Azteca in Mexico City, but the Chargers are the designated home team. It’s the last international game of the 2019 season and first meeting between AFC West rivals who split last year. The Chargers’ playoff hopes are in major jeopardy after a 26-24 loss in Oakland last Thursday. Philip Rivers had the ball with about a minute left, only needing to get into field-goal range and three timeouts but couldn’t do anything. He simply wasn’t good in the loss, picked off three times. Patrick Mahomes returned from injury for the Chiefs and had a huge day at Tennessee but the Chiefs lost.

Point spread: Chiefs -3.5

Pick ATS: Los Angeles