The final Monday night game of the regular season is also a rematch of last season’s NFC Championship Game as the Detroit Lions visit the San Francisco 49ers.
The Lions are 3.5-point favourites on the NFL odds with a total of 51.
NFL Point Spread and Betting Analysis
The Detroit Lions are the only NFC club to never reach the Super Bowl. Back on Jan. 28 at Levi’s Stadium, it looked like that drought might end as the Lions were up 24-7 in the third quarter on the San Francisco 49ers in the NFC Championship Game. Of course, the Niners rallied for a 34-31 victory thanks in part to a fluke 51-yard catch by the Niners’ Brandin Aiyuk on a Brock Purdy pass that deflected off a defender’s facemask and into Aiyuk’s hands. That will be remembered forever in franchise history.
The Niners and Lions were the two betting favourites to win the NFC entering this season and Detroit has played up to expectations but San Francisco has not in part due to a lot of serious injuries and will not be in the postseason for the first time since 2020. The Pro Bowler Aiyuk and running back Christian McCaffrey, the 2023 NFL Offensive Player of the Year, are both out for the season among some others.
San Francisco leads the all-time series 40-28-1 (including three playoff matchups) and this is their first regular-season meeting since the 2021 season opener when the Lions were still a bad team.
Detroit Lions
Detroit was an easy 34-17 winner in Chicago on Sunday but Minnesota also won in Week 16 so the teams remain tied atop the NFC North ahead of the Lions hosting the Vikings in Week 18. That game could be not for just the division but also for the conference’s top seed after fellow contender Philadelphia lost on Sunday to fall a game back in that chase. Sunday was the Lions’ first game since losing co-No. 1 running back David Montgomery for at least the rest of the regular season, and Jahmyr Gibbs picked up the slack with 154 yards from scrimmage and a TD. Jared Goff continued his MVP-calibre season with 336 yards passing and three scores and became the fourth QB in league history with at least 800 passing yards and eight TD passes with no picks in any two-game span. His 33 pass TDs on the year are a career high and second in team history. Wideout Amon-Ra St. Brown, meanwhile, became the first player in team history with at least 100 catches, 1,000 receiving yards and 10 TDs in back-to-back seasons. Detroit’s 13 wins are a single-season franchise record. It is 7-0 SU in its past seven road games.
San Francisco 49ers
The Niners were eliminated from playoff contention before they took the field Sunday and then went out and lost 29-17 in Miami – I wonder if we see more than few banged-up key San Francisco players now shut down for the season. Pro Bowl left tackle Trent Williams, for example, hasn’t played in weeks and there’s no point bringing him back now. Linebacker Dre Greenlaw left early Sunday with an injury and as a pending free agent, it wouldn’t be smart for him to try and play the final two games. Guard Aaron Banks left with a right knee injury in the second half and we have seen the last of him in 2024. We should see Pro Bowl tight end George Kittle at least one more game as he’s 33 yards shy of becoming the fifth tight end in NFL history with four or more seasons with 1,000 receiving yards. San Francisco will become the third team in the last 15 seasons to finish with a losing record after a Super Bowl loss. It is 1-6 ATS in the past seven games.
NFL Prediction: Who Will Win Lions vs. 49ers?
Line History
Sports Interaction customers are placing their bets on:
time | fav | line | total |
---|---|---|---|
Opening 23 Dec 12:34am | - | - | O +52 -110 |
Closing 31 Dec 3:43am | - | - | O +5 -130 |
- Regular Season
- Playoffs
Lions Team Leaders
Touchdowns |
13 |
Rushing |
775 |
Passing |
62 |
Receiving |
60 |
Sacks |
7.5 |
Interceptions |
9 |
Touchdowns |
6 |
Rushing |
789 |
Passing |
3864 |
Receiving |
77 |
Sacks |
8.5 |
Interceptions |
2 |
Touchdowns |
1 |
Rushing |
61 |
Passing |
20 |
Receiving |
6 |
Sacks |
0 |
Interceptions |
0 |
Touchdowns | |
Rushing | |
Passing | Did not qualify |
Receiving | |
Sacks | |
Interceptions |
- Regular Season
- Playoffs
49ers Team Leaders
Touchdowns |
13 |
Rushing |
775 |
Passing |
62 |
Receiving |
60 |
Sacks |
7.5 |
Interceptions |
9 |
Touchdowns |
6 |
Rushing |
789 |
Passing |
3864 |
Receiving |
77 |
Sacks |
8.5 |
Interceptions |
2 |
Touchdowns |
1 |
Rushing |
61 |
Passing |
20 |
Receiving |
6 |
Sacks |
0 |
Interceptions |
0 |
Touchdowns | |
Rushing | |
Passing | Did not qualify |
Receiving | |
Sacks | |
Interceptions |
Weather

temp | 48 |
condition | sunny |
wind | Northwest 5mph |
Injuries
Amik Robertson (CB)
Pat O'Connor (DL)
Kevin Zeitler (G)
Terrion Arnold (CB)
Christian Mahogany (OL)
Craig Reynolds (RB)
Jack Campbell (LB)
Emmanuel Moseley (CB)
Amik Robertson (CB)
Penei Sewell (OT)
Ji'ayir Brown (S)
Deommodore Lenoir (DB)
Colton McKivitz (OL)
Ricky Pearsall (WR)
Deebo Samuel Sr. (WR)
Isaac Yiadom (CB)
Demetrius Flannigan-Fowles (LB)
Leonard Floyd (DL)
Brock Purdy (QB)
Charvarius Ward (CB)
Injuries
player (position) | status | ats*current | o/u* | notes | |
---|---|---|---|---|---|
Amik Robertson (CB) | Questionable | Elbow - 18 / 01 / 25 | 1-0 | 0-1 | + - |
Robertson left the game with an elbow injury, and it has yet to be determined if he will be available for the next game. |
|||||
Pat O'Connor (DL) | Questionable | Calf - 16 / 01 / 25 | 1-0 | 0-1 | + - |
O'Connor is nursing a calf injury, and it remains to be seen if he will dress against the Commanders on Saturday, January 18th. |
|||||
Kevin Zeitler (G) | Out | Hamstring - 07 / 01 / 25 | 1-0 | 0-1 | + - |
Zeitler is bothered by a hamstring injury, and he is unlikely to dress against the Commanders on Saturday, January 18th. |
|||||
Terrion Arnold (CB) | Questionable | Foot - 06 / 01 / 25 | 2-0 | 1-1 | + - |
Arnold suffered a foot injury, and it is uncertain if he will suit up against the Commanders on Saturday, January 18th. |
|||||
Christian Mahogany (OL) | Questionable | Illness - 03 / 01 / 25 | 2-0 | 1-1 | + - |
Mahogany is ailing with an illness, and it is uncertain if he will play against the Commanders on Saturday, January 18th. |
|||||
Craig Reynolds (RB) | Questionable | Back - 03 / 01 / 25 | 2-0 | 1-1 | + - |
Reynolds is dealing with a back injury, and it is up in the air if he will be active against the Vikings on Sunday, January 5th. |
|||||
Jack Campbell (LB) | Questionable | Ribs - 02 / 01 / 25 | 2-0 | 1-1 | + - |
Campbell is nursing a rib injury, and it is uncertain if he will dress against the Vikings on Sunday, January 5th. |
|||||
Emmanuel Moseley (CB) | Questionable | Illness - 02 / 01 / 25 | 2-0 | 1-1 | + - |
Moseley is ailing with an illness, and it is unclear if he will take the field against the Commanders on Saturday, January 18th. |
|||||
Amik Robertson (CB) | Questionable | Calf - 02 / 01 / 25 | 2-0 | 1-1 | + - |
Robertson is hampered with a calf injury, and it is unknown if he will take the field against the Vikings on Sunday, January 5th. |
|||||
Penei Sewell (OT) | Questionable | Thumb - 31 / 12 / 24 | 3-0 | 2-1 | + - |
Sewell is nursing a thumb injury, and it is up in the air if he will take the field against the Vikings on Sunday, January 5th. |
player (position) | status | ats*current | o/u* | notes | |
---|---|---|---|---|---|
Ji'ayir Brown (S) | Questionable | Ankle - 02 / 01 / 25 | 0-1 | 1-0 | + - |
Brown is dealing with an ankle injury, and it is unclear if he will be available against the Cardinals on Sunday, January 5th. |
|||||
Deommodore Lenoir (DB) | Out | Shoulder - 02 / 01 / 25 | 0-1 | 1-0 | + - |
Lenoir is battling with a shoulder injury, and he is unlikely to be active against the Cardinals on Sunday, January 5th. |
|||||
Colton McKivitz (OL) | Questionable | Knee - 02 / 01 / 25 | 0-1 | 1-0 | + - |
McKivitz is is hampered by a knee injury, and it is uncertain if he will play against the Cardinals on Sunday, January 5th. |
|||||
Ricky Pearsall (WR) | Questionable | Illness - 02 / 01 / 25 | 0-1 | 1-0 | + - |
Pearsall is dealing with an illness, and it is unclear if he will be available against the Cardinals on Sunday, January 5th. |
|||||
Deebo Samuel Sr. (WR) | Out | Ribs - 02 / 01 / 25 | 0-1 | 1-0 | + - |
Samuel is nursing a ribs injury, and he is unlikely to be active against the Cardinals on Sunday, January 5th. |
|||||
Isaac Yiadom (CB) | Questionable | Pelvis - 02 / 01 / 25 | 0-1 | 1-0 | + - |
Yiadom is nursing a pelvis injury, and it is unclear if he will play against the Cardinals, on Sunday, January 5th. |
|||||
Demetrius Flannigan-Fowles (LB) | Out indefinitely | Calf - 31 / 12 / 24 | 0-2 | 2-0 | + - |
Flannigan-Fowles has been placed on injured reserve with a calf injury, and it is unknown how long he will be debilitated. |
|||||
Leonard Floyd (DL) | Questionable | Shoulder - 31 / 12 / 24 | 0-2 | 2-0 | + - |
Floyd is battling a shoulder injury, and it is unclear if he will be active against the Cardinals on Sunday, January 5th. |
|||||
Brock Purdy (QB) | Out | Elbow - 31 / 12 / 24 | 0-2 | 2-0 | + - |
Purdy is nursing an elbow injury, and he is not expected to dress against the Cardinals on Sunday, January 5th. |
|||||
Charvarius Ward (CB) | Questionable | Personal - 29 / 12 / 24 | 0-2 | 2-0 | + - |
Ward is dealing with a personal matter, and it is uncertain if he will participate against the Cardinals on Sunday, January 5th. |
-
Line History
Sports Interaction customers are placing their bets on:
time fav line total Opening 23 Dec 12:34am - - O +52 -110 Closing 31 Dec 3:43am - - O +5 -130 -
- Regular Season
- Playoffs
Lions Team Leaders
Touchdowns 13
Rushing 775
Passing 62
Receiving 60
Sacks 7.5
Interceptions 9
Touchdowns 6
Rushing 789
Passing 3864
Receiving 77
Sacks 8.5
Interceptions 2
Touchdowns 1
Rushing 61
Passing 20
Receiving 6
Sacks 0
Interceptions 0
Touchdowns Rushing Passing Did not qualify Receiving Sacks Interceptions -
- Regular Season
- Playoffs
49ers Team Leaders
Touchdowns 13
Rushing 775
Passing 62
Receiving 60
Sacks 7.5
Interceptions 9
Touchdowns 6
Rushing 789
Passing 3864
Receiving 77
Sacks 8.5
Interceptions 2
Touchdowns 1
Rushing 61
Passing 20
Receiving 6
Sacks 0
Interceptions 0
Touchdowns Rushing Passing Did not qualify Receiving Sacks Interceptions -
Weather
temp 48 condition sunny wind Northwest 5mph -
Injuries
Amik Robertson (CB)
Questionable Elbow - 18 / 01 / 25Pat O'Connor (DL)
Questionable Calf - 16 / 01 / 25Kevin Zeitler (G)
Out Hamstring - 07 / 01 / 25Terrion Arnold (CB)
Questionable Foot - 06 / 01 / 25Christian Mahogany (OL)
Questionable Illness - 03 / 01 / 25Craig Reynolds (RB)
Questionable Back - 03 / 01 / 25Jack Campbell (LB)
Questionable Ribs - 02 / 01 / 25Emmanuel Moseley (CB)
Questionable Illness - 02 / 01 / 25Amik Robertson (CB)
Questionable Calf - 02 / 01 / 25Penei Sewell (OT)
Questionable Thumb - 31 / 12 / 24Ji'ayir Brown (S)
Questionable Ankle - 02 / 01 / 25Deommodore Lenoir (DB)
Out Shoulder - 02 / 01 / 25Colton McKivitz (OL)
Questionable Knee - 02 / 01 / 25Ricky Pearsall (WR)
Questionable Illness - 02 / 01 / 25Deebo Samuel Sr. (WR)
Out Ribs - 02 / 01 / 25Isaac Yiadom (CB)
Questionable Pelvis - 02 / 01 / 25Demetrius Flannigan-Fowles (LB)
Out indefinitely Calf - 31 / 12 / 24Leonard Floyd (DL)
Questionable Shoulder - 31 / 12 / 24Brock Purdy (QB)
Out Elbow - 31 / 12 / 24Charvarius Ward (CB)
Questionable Personal - 29 / 12 / 24Injuries
player (position) status ats*current o/u* notes Amik Robertson (CB) Questionable Elbow - 18 / 01 / 25 1-0 0-1 + - Robertson left the game with an elbow injury, and it has yet to be determined if he will be available for the next game.
Pat O'Connor (DL) Questionable Calf - 16 / 01 / 25 1-0 0-1 + - O'Connor is nursing a calf injury, and it remains to be seen if he will dress against the Commanders on Saturday, January 18th.
Kevin Zeitler (G) Out Hamstring - 07 / 01 / 25 1-0 0-1 + - Zeitler is bothered by a hamstring injury, and he is unlikely to dress against the Commanders on Saturday, January 18th.
Terrion Arnold (CB) Questionable Foot - 06 / 01 / 25 2-0 1-1 + - Arnold suffered a foot injury, and it is uncertain if he will suit up against the Commanders on Saturday, January 18th.
Christian Mahogany (OL) Questionable Illness - 03 / 01 / 25 2-0 1-1 + - Mahogany is ailing with an illness, and it is uncertain if he will play against the Commanders on Saturday, January 18th.
Craig Reynolds (RB) Questionable Back - 03 / 01 / 25 2-0 1-1 + - Reynolds is dealing with a back injury, and it is up in the air if he will be active against the Vikings on Sunday, January 5th.
Jack Campbell (LB) Questionable Ribs - 02 / 01 / 25 2-0 1-1 + - Campbell is nursing a rib injury, and it is uncertain if he will dress against the Vikings on Sunday, January 5th.
Emmanuel Moseley (CB) Questionable Illness - 02 / 01 / 25 2-0 1-1 + - Moseley is ailing with an illness, and it is unclear if he will take the field against the Commanders on Saturday, January 18th.
Amik Robertson (CB) Questionable Calf - 02 / 01 / 25 2-0 1-1 + - Robertson is hampered with a calf injury, and it is unknown if he will take the field against the Vikings on Sunday, January 5th.
Penei Sewell (OT) Questionable Thumb - 31 / 12 / 24 3-0 2-1 + - Sewell is nursing a thumb injury, and it is up in the air if he will take the field against the Vikings on Sunday, January 5th.
player (position) status ats*current o/u* notes Ji'ayir Brown (S) Questionable Ankle - 02 / 01 / 25 0-1 1-0 + - Brown is dealing with an ankle injury, and it is unclear if he will be available against the Cardinals on Sunday, January 5th.
Deommodore Lenoir (DB) Out Shoulder - 02 / 01 / 25 0-1 1-0 + - Lenoir is battling with a shoulder injury, and he is unlikely to be active against the Cardinals on Sunday, January 5th.
Colton McKivitz (OL) Questionable Knee - 02 / 01 / 25 0-1 1-0 + - McKivitz is is hampered by a knee injury, and it is uncertain if he will play against the Cardinals on Sunday, January 5th.
Ricky Pearsall (WR) Questionable Illness - 02 / 01 / 25 0-1 1-0 + - Pearsall is dealing with an illness, and it is unclear if he will be available against the Cardinals on Sunday, January 5th.
Deebo Samuel Sr. (WR) Out Ribs - 02 / 01 / 25 0-1 1-0 + - Samuel is nursing a ribs injury, and he is unlikely to be active against the Cardinals on Sunday, January 5th.
Isaac Yiadom (CB) Questionable Pelvis - 02 / 01 / 25 0-1 1-0 + - Yiadom is nursing a pelvis injury, and it is unclear if he will play against the Cardinals, on Sunday, January 5th.
Demetrius Flannigan-Fowles (LB) Out indefinitely Calf - 31 / 12 / 24 0-2 2-0 + - Flannigan-Fowles has been placed on injured reserve with a calf injury, and it is unknown how long he will be debilitated.
Leonard Floyd (DL) Questionable Shoulder - 31 / 12 / 24 0-2 2-0 + - Floyd is battling a shoulder injury, and it is unclear if he will be active against the Cardinals on Sunday, January 5th.
Brock Purdy (QB) Out Elbow - 31 / 12 / 24 0-2 2-0 + - Purdy is nursing an elbow injury, and he is not expected to dress against the Cardinals on Sunday, January 5th.
Charvarius Ward (CB) Questionable Personal - 29 / 12 / 24 0-2 2-0 + - Ward is dealing with a personal matter, and it is uncertain if he will participate against the Cardinals on Sunday, January 5th.